المؤلفون: Babangida Shehu Bappah, Idoo Womboh, Patrick Ayi Ewah, Lawan Umar, Jibril Mohammed

المصدر: Bulletin of the National Research Centre, Vol 48, Iss 1, Pp 1-5 (2024)

مصطلحات موضوعية: Guillain–Barré syndrome, Incentive spirometry, Progressive muscle training, Respiratory muscle weakness, Respiratory support, Science

الوصف: Abstract Background Guillain–Barré syndrome (GBS) is one of the most common causes of acute neuromuscular paralysis in developed and developing countries. It is a complex autoimmune disorder characterized by progressive skeletal muscle weakness, potentially involving respiratory muscles. The purpose of this case report was to explore the importance of combined use of incentive spirometry and progressive muscle training as essential therapies in a 20-year-old male diagnosed with GBS. Case presentation This is a case report of a 20-year-old Nigerian male university student who was brought to the trauma center on a wheelchair with weakness of both upper and lower limbs which was said to be progressive, and a diagnosis of GBS was made by the attending physician. On examination, he was discovered to have quadriparesis with mild respiratory muscle involvement. He deteriorated with cardiopulmonary compromise and was transferred into intensive care unit. He was managed with supplementary oxygen therapy until there was significant improvement and he was weaned off oxygen therapy and then needed further evaluation and management. The patient was placed on immunoglobulin in conjunction with incentive spirometry, progressive strengthening exercise and exercise training which proved to be effective as he regained all the lost function within a few weeks of symptoms. Results This intervention delves into the synergistic potential of fortifying respiratory muscles and improving respiratory function alongside overall muscle strength which resulted in the patient regaining all the lost function within a few weeks. Conclusions The combined use of incentive spirometry and progressive muscle training in addition to immunoglobulin was effective in modulating GBS related impairments. We recommend the use of a multifaceted strategy in the management of patients with GBS and other similar health conditions.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2522-8307Test

الوصول الحر: https://doaj.org/article/b715701d2682446a97cc37a082e6ef21Test

المؤلفون: Hassan M. Habib, Zahra M. Serry, Sabah A. Hussein, Ebtesam N. Nagy, Mona A. Ghallab

المصدر: Physiotherapy Quarterly, Vol 32, Iss 1, Pp 50-56 (2024)

مصطلحات موضوعية: chronic obstructive pulmonary disease, dyspnoea, exercise tolerance, respiratory muscle weakness, russian current, Medicine

الوصف: Introduction Expiratory muscle weakness and dyspnoea are common in patients suffering from chronic obstructive pulmonary disease (COPD) and negatively affect their exercise capacity. We aimed to highlight the combined effect of Russian current and a threshold positive expiratory pressure (PEP) device on expiratory muscle strength, dyspnoea, and functional capacity in patients with COPD. Methods A total of 60 males with COPD were involved in this controlled randomised trial (age ranged 55–65 years and median body mass index [BMI] was 28.68–25.96) and randomly assigned into two equal groups (30 for each), to receive combined Russian current and PEP device (study group) or PEP device only (control group), for three sessions per week over a ten-week period. Maximum expiratory pressure (MEP), dyspnoea (modified Borg scale – MBS), and functional capacity (6-minute walk test) were assessed before and after the intervention. Results There was statistically significant improvement in all measured variables (MEP, MBS, and 6-minute walk test) in either the study group or the control group according to Wilcoxon’s sign rank test (all were p < 0.001 and p < 0.01, respectively), however, the study group showed a more significant improvement compared to the control group according to the Mann–Whitney U -test ( p < 0.001). Conclusions Combined Russian current and PEP device had a superior beneficial effect on improving dyspnoea and functional capacity by boosting the expiratory muscle strength in COPD patients, which could be implemented in their management, although further studies are needed to evaluate its maintenance effect.

وصف الملف: electronic resource

العلاقة: https://physioquart.awf.wroc.pl/Impact-of-combined-Russian-current-and-threshold-PEP-on-dyspnoea-and-functional-capacity,152984,0,2.htmlTest; https://doaj.org/toc/2544-4395Test

الوصول الحر: https://doaj.org/article/46b57f5944f94500bd90a622284ddae4Test

المؤلفون: Khanbabaee, Ghamartaj, Karim Zadeh, Parvaneh, Nasehi, Mohammad Mahdi, Tabatabaii, Seyed Ahmad, pourghasem, Matin, Alaei, Fariba, Sadr, Saeed, Farahbakhsh, Nazanin, Modarresi, Seyedeh Zalfa, Khazaii, Fatemeh, Soflaee, Maedeh, taghizadeh behbahani, Abdolhamid, Fadavi, Nafiseh, Pourghasem, Mahsa

المصدر: Iranian Journal of Child Neurology; Vol. 17 No. 2 (2023): spring; 9-17 ; 2008-0700 ; 1735-4668

مصطلحات موضوعية: Neuromuscular diseases (NMDs), respiratory muscle weakness(RMW), Respiratory involvement, Pulmonary Involvement in Neuromuscular Diseases: A review

الوصف: Neuromuscular diseases (NMDs) affect muscle function directly or indirectly by affecting nerves or neuromuscular junctions. One of the leading causes of death in patients with NMD is respiratory muscleweakness (RMW). Respiratory involvement in patients with NMD can manifest widely, from mild failure that may initially affect only sleep to severe failure that can be life-threatening. Care approaches include arranged and precise clinical follow-ups of signs of sleep-disordered breathing, daytime hypoventilation, coughing, and swallowing disturbances. This manuscript will review the mechanisms and abnormalities of respiratory function in patients with NMD and help optimize NMD management.

وصف الملف: application/pdf

العلاقة: https://journals.sbmu.ac.ir/ijcn/article/view/40131/31025Test; https://journals.sbmu.ac.ir/ijcn/article/view/40131Test

الإتاحة: https://doi.org/10.22037/ijcn.v17i2.40131Test
https://journals.sbmu.ac.ir/ijcn/article/view/40131Test

المؤلفون: Haiyan Cao, Xiaoming Chen, Xuyan Ren, Zhiguo Chen, Chuandao Liu, Jianqiang Ni, Haoyu Liu, Yingjie Fan, Dandan Xu, Huaping Jin, Jie Bao, Huang Yulun, Min Su

المصدر: Frontiers in Aging Neuroscience, Vol 14 (2022)

مصطلحات موضوعية: respiratory muscle weakness, pulmonary dysfunction, transcranial magnetic stimulation, respiratory muscle training, ischemic stroke, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

الوصف: Respiratory muscle weakness often occurs after stroke, which can lead to pulmonary dysfunction (PD). Pulmonary dysfunction prolongs the length of hospital stay and increases the risk of death. In a prospective, randomized, case-control study, we used musculoskeletal ultrasonography (MSUS), and pulmonary function tester to objectively evaluate the efficacy of repetitive transcranial magnetic stimulation (rTMS) combined with respiratory muscle training (RMT) in the treatment of PD in patients with acute ischemic stroke. Sixty-two stroke patients with PD were recruited and eventually 60 patients participated in this study. The control group was treated with RMT, and the treatment group was treated with rTMS on the basis of RMT. Treatment occurred five times a week for 8 weeks. Before and after treatment, diaphragmatic thickness (DT), diaphragmatic thickening fraction (DTF) and diaphragmatic mobility (DM) in patients, bilateral chest wall were measured by MSUS. Meanwhile, FVC, FEV1, FEV1/FVC, PEF, and MVV tested by pulmonary function tester was used to evaluate the improvement of lung functional. activities of daily living (ADL) was used as an objective criterion to evaluate the overall functional recovery of patients before and after treatment. After treatment, DT, DTF, and DM values improved significantly in both the affected and unaffected sides. The FVC, FEV1, FEV1/FVC, PEF, MVV, and ADL were all increased after the treatment. Combined treatment showed a stronger increase than that by RMT treatment alone. The study preliminarily shows that rTMS and RMT could improve lung functional after acute ischemic stroke.

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fnagi.2022.1006696/fullTest; https://doaj.org/toc/1663-4365Test

الوصول الحر: https://doaj.org/article/4949290835d64937b1d3e5922f946307Test

المؤلفون: Palaparthi Sai Krishna Chaitanya, V Suresh, Alladi Mohan, Alok Sachan

المصدر: Journal of Clinical and Scientific Research, Vol 8, Iss 2, Pp 89-94 (2019)

مصطلحات موضوعية: hypothyroidism, obstructive sleep apnoea, respiratory muscle weakness, restrictive lung disease, Medicine

الوصف: Hypothyroidism is one of the most common endocrine disorders in adults. While it affects almost all systems of the body, little attention has been paid to the involvement of the respiratory system and its function in hypothyroidism. The present review summarises the available literature on respiratory function in patients with hypothyroidism. Hypothyroidism has myriad effects on respiratory function. It is known to cause upper airway obstruction during sleep causing sleep disordered breathing (obstructive sleep apnoea). It affects the respiratory drive causing reduced responsiveness to hypoxia or hypercapnia, potentially causing life-threatening hypoventilation on rare occasions. Pleural effusions solely attributable to hypothyroidism are a relatively uncommon occurrence. Deficiency of thyroid hormones reduces the strength of the respiratory muscles. A reduction in diffusion lung capacity for carbon monoxide points to lung parenchymal involvement as well. These two changes lead to a predominantly restrictive pulmonary physiology on spirometry. Studies show that the restrictive pattern improves after thyroxin replacement. Since pulmonary involvement is a relatively underevaluated aspect of hypothyroidism, more studies in this area are the need of the hour, to fill the current lacunae in our knowledge and understanding.

وصف الملف: electronic resource

العلاقة: http://www.jcsr.co.in/article.asp?issn=2277-5706;year=2019;volume=8;issue=2;spage=89;epage=94;aulast=KrishnaTest; https://doaj.org/toc/2277-5706Test; https://doaj.org/toc/2277-8357Test

الوصول الحر: https://doaj.org/article/24da1e31a9814a9b85abe91ea0cfa6a0Test

المؤلفون: Akitoshi Takeda, Hiroko Kimura, Ichizo Nishino, Kenta Aohara, Yasuhiro Izumiya, Yoshiaki Itoh, 伊藤 義彰, 木村 裕子, 武田 景敏, 泉家 康宏, 西野 一三, 青原 健太

المصدر: 臨床神経学 / Rinsho Shinkeigaku. 2022, 62(9):726

المؤلفون: Tomoyuki Morisawa, Yota Kunieda, Shingo Koyama, Mizue Suzuki, Yuma Takahashi, Tomokazu Takakura, Yuta Kikuchi, Tadamitsu Matsuda, Yuji Fujino, Ryuichi Sawa, Akihiro Sakuyama, Masakazu Saitoh, Tetsuya Takahashi, Toshiyuki Fujiwara

المصدر: International Journal of Environmental Research and Public Health; Volume 18; Issue 24; Pages: 13257

مصطلحات موضوعية: sarcopenia, respiratory muscle weakness, older adults, physical performance, physical activity

جغرافية الموضوع: agris

الوصف: An association between respiratory muscle weakness and sarcopenia may provide a clue to the mechanism of sarcopenia development. We aimed to clarify this relationship among community-dwelling older adults. In total, 117 community-dwelling older adults were assessed and classified into 4 groups: robust, respiratory muscle weakness, sarcopenia, and respiratory sarcopenia. The respiratory sarcopenia group (12%) had a significantly higher percentage of males and had lower BMI, skeletal muscle index, skeletal muscle mass, phase angle, and oral function than the robust group (32.5%). All physical functions were significantly lower. The respiratory muscle weakness group (54.7%) had a significantly lower BMI and slower walking speed, compared with the robust group. The sarcopenia group (0.8%) was excluded from the analysis. The percent maximum inspiratory pressure was significantly lower in both the respiratory muscle weakness and respiratory sarcopenia groups, compared with the robust group. Almost all participants with sarcopenia showed respiratory muscle weakness. In addition, approximately 50% had respiratory muscle weakness, even in the absence of systemic sarcopenia, suggesting that respiratory muscle weakness may be the precursor of sarcopenia. The values indicating physical function and skeletal muscle mass in the respiratory muscle weakness group were between those in the robust and the respiratory sarcopenia groups.

وصف الملف: application/pdf

العلاقة: https://dx.doi.org/10.3390/ijerph182413257Test

الإتاحة: https://doi.org/10.3390/ijerph182413257Test

المؤلفون: Sahara N. Saltijeral, Maria Cabanillas, Anne Kleiman, Horiana B. Grosu

المصدر: Journal of Clinical and Translational Endocrinology Case Reports, Vol 17, Iss , Pp 100066- (2020)

مصطلحات موضوعية: Medullary thyroid cancer, Vandetanib, Tyrosine kinase inhibitor, Respiratory muscle weakness, Chronic hypercapnic respiratory failure, Tremor, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

الوصف: The present report describes the case of a 65-year-old white woman with a longstanding diagnosis of medullary thyroid cancer with metastatic disease and an extensive surgical history.She presented with late-onset folliculitis, hypertension, parkinsonian-type syndrome, and respiratory muscle weakness, and she developed chronic hypercapnic respiratory failure during treatment with Vandetanib. Her symptoms improved with reduction of the dosage but then worsened again when the dosage was increased. Prescribing physicians should reduce the dose of Vandetanib to the minimal levels required for therapeutic effect to avoid potentially life-threatening toxic effects.

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2214624520300113Test; https://doaj.org/toc/2214-6245Test

الوصول الحر: https://doaj.org/article/4679ba2915db4f4192c3f50f34df8a79Test

المؤلفون: Shuhei Yamamoto, Yasunari Sakai, Takayoshi Yamaga, Takashi Ichiyama

المصدر: BMJ case reports. 14(7)

مصطلحات موضوعية: Male, medicine.medical_specialty, Vital capacity, Adolescent, medicine.medical_treatment, Breathing Exercises, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Respiratory muscle weakness, Lung transplantation, Humans, Respiratory function, Pulmonary rehabilitation, 030212 general & internal medicine, Child, Paediatric patients, business.industry, Inspiratory muscle training, General Medicine, Respiratory Muscles, Transplantation, Dyspnea, 030228 respiratory system, Cardiology, Quality of Life, business, Lung Transplantation

الوصف: Pulmonary rehabilitation is a cornerstone of management for patients after lung transplantation (LT), but the benefits of inspiratory muscle training (IMT) after LT in children are unclear. Therefore, we examined whether IMT can improve respiratory function and dyspnoea in a paediatric patient after LT.The patient was a 13-year-old boy who underwent double LT. However, mild physical activity such as walking triggered dyspnoea for the patient. The patient underwent IMT with the intensity of approximately 30% of his maximal inspiratory pressure (MIP) for 2 months.The patient’s MIP was increased by approximately 60% after 2 months, and his forced vital capacity as a percent of the predicted normal value increased from 74.6% to 83.4%, with improvement of dyspnoea.IMT may help improve dyspnoea after LT in children with respiratory muscle weakness and a decline in respiratory function.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6177fe341fd90a07616385f10fc95e80Test
https://pubmed.ncbi.nlm.nih.gov/34290002Test

المؤلفون: Amy M. Pastva, Julia K. L. Walker

المصدر: Frontiers in Physiology, Vol 9 (2018)

مصطلحات موضوعية: respiratory muscle weakness, exercise training, heterodimer receptor, blood-brain barrier, ventilatory overdrive, angiotensin drive to breathe, Physiology, QP1-981

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/article/10.3389/fphys.2018.00554/fullTest; https://doaj.org/toc/1664-042XTest

الوصول الحر: https://doaj.org/article/ec46f299136c48c4b18708f281c19510Test