المؤلفون: Jun Zhao^1,2, Na Liu^2,3, Xinhe Hao¹, Lin Que², Jiyuan Liu^2,4, Xiufa Tang^2,4 81561632@qq.com

المصدر: Oncology Letters. Dec2017, Vol. 14 Issue 6, p7705-7714. 10p. 1 Color Photograph, 1 Chart, 4 Graphs.

مصطلحات موضوعية: *SQUAMOUS cell carcinoma, *INTEGRIN-linked kinase, *FLOW cytometry, *PROTEIN expression, *APOPTOSIS, *PATIENTS

المؤلفون: ZHOU Li-ping, MAO Xiao-chun, LI Qin

المصدر: Jichu yixue yu linchuang, Vol 40, Iss 8, Pp 1090-1095 (2020)

مصطلحات موضوعية: retinal vascular endothelial cells, high glucose level, mir-1908, integrin-linked kinase, cell apoptosis, Medicine

وصف الملف: electronic resource

العلاقة: http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a190613.pdfTest; https://doaj.org/toc/1001-6325Test

الوصول الحر: https://doaj.org/article/a63ab48f407c46d9858c95ca04f636faTest

المؤلفون: Martin, Isabel M., Nava, Michele M., Wickström, Sara A., Graeter, Frauke

المساهمون: STEMM - Stem Cells and Metabolism Research Program, Helsinki Institute of Life Science HiLIFE, University of Helsinki

مصطلحات موضوعية: focal adhesion, integrin-linked kinase, molecular dynamics, traction force microscopy, STRUCTURAL BASIS, THERAPEUTIC TARGET, CELL-ADHESION, ALPHA-PARVIN, ILK, DOMAIN, PINCH, KINDLIN-2, BINDING, LOCALIZATION, 1182 Biochemistry, cell and molecular biology

وصف الملف: application/pdf

العلاقة: We acknowledge Anu M. Luoto for technical assistance. This work was supported by the Klaus Tschira Foundation; the state of BadenWurttemberg through bwHPC; the German Research Foundation through Grant INST 35/1134-1 FUGG (to F.G.); the Helsinki Institute of Life Science; the Sigrid Juselius Foundation; and Academy of Finland Grant 317597 (to S.A.W.). Molecular graphics and analyses were partially performed with UCSF Chimera, developed by the Resource for Biocomputing, Visualization, and Informatics at the University of California San Francisco, with support from NIH Grant P41GM103311.; Martin , I M , Nava , M M , Wickström , S A & Graeter , F 2022 , ' ATP allosterically stabilizes integrin-linked kinase for efficient force generation ' , Proceedings of the National Academy of Sciences of the United States of America , vol. 119 , no. 11 , 2106098119 . https://doi.org/10.1073/pnas.2106098119Test; ORCID: /0000-0001-8733-6364/work/117949109; ORCID: /0000-0001-6383-6292/work/156156175; http://hdl.handle.net/10138/347201Test; 27c74b8b-7cd2-4e16-9d73-a1a064961395; 000771757800001

الإتاحة: http://hdl.handle.net/10138/347201Test

المؤلفون: Ortega, Miguel A., Chaowen, Chen, Fraile Martínez, Oscar, García Montero, Cielo, Sáez García, Miguel Ángel, Cruza, Iris, Pereda Cerquella, Claude, Álvarez Mon, Miguel Ángel, Guijarro, Luis G., Fatych, Yuliia, Menor Salván, César, Álvarez Mon, Melchor, León Luis, Juan Antonio, Buján, Julia, García Honduvilla, Natalio, Bravo Arribas, Coral, Asúnsolo del Barco, Angel

مصطلحات موضوعية: 618.2, Chronic venous disease (CVD), Pregnancy, Integrin-linked kinase (ILK), Cadherins, Cell behavior, Extracellular matrix (ECM), Medicina, Ginecología y obstetricia, 32 Ciencias Médicas, 3201.08 Ginecología

وصف الملف: application/pdf

العلاقة: FEDER; B2017/BMD-3804 MITIC-CM, B2020/MITICAD-CM; Plan Estatal de I + D+I 2013–2016 (FIS-PI18/00912, PI21/01244); https://doi.org/10.3390/jpm12020277Test; https://www.mdpi.com/2075-4426/12/2/277Test; https://hdl.handle.net/20.500.14352/73358Test

الإتاحة: https://doi.org/20.500.14352/73358Test
https://doi.org/10.3390/jpm12020277Test
https://hdl.handle.net/20.500.14352/73358Test
https://www.mdpi.com/2075-4426/12/2/277Test

المؤلفون: Griera Merino, Mercedes, Hatem Vaquero, Marco Antonio, Campillo de Blas, Sofía, Gutiérrez Calabrés, Elena, García Ayuso, Diego, Pardo, María, Calleros Basilio, Laura, Rodríguez Puyol, Manuel, Rodríguez Puyol, Diego María, Frutos García, Sergio de

المساهمون: Universidad de Alcalá. Departamento de Biología de Sistemas

مصطلحات موضوعية: Tirofban, Integrin-beta1, Integrin-linked kinase, AKT, Adipogenesis, Obesity, Hypertrophic adipocyte, Browning, White adipose tissue, Lipolysis, Inflammation, Biología y Biomedicina, Biology

وصف الملف: application/pdf

العلاقة: Info:eu-repo/grantAgreement/MINECO/ Programa Estatal de I+D+I Orientada a los Retos de la Sociedad/PI14%2F01939/ES/PAPEL DE LA KINASA LIGADA A INTEGRINAS EN LAS ALTERACIONES DEL METABOLISMO DE LOS HIDRATOS DE CARBONO Y EN LA GÉNESIS DEL DAÑO TISULAR ASOCIADO/; info:eu-repo/grantAgreement/MINECO/Programa Estatal de I+D+I Orientada a los Retos de la Sociedad/PI14%2F02075/ES/Importancia de la Kinasa Ligada a Integrinas en la progresión de la enfermedad renal crónica (ERC) y en la génesis del daño vascular asociado a la misma/; info.eu-repo/grantAgreement/MINECO/Programa Estatal de I+D+I Orientada a los Retos de la Sociedad/PI17%2F01513/ES/Kinasa ligada a integrinas: posible biomarcador de progresión de la enfermedad renal crónica (ERC) y modulador de la disfunción monocitaria responsable del daño cardiovascular/; info:eu-repo/grantAgreement/MINECO/Acción estratégica en Salud 2013-2016/PI17%2F00625/ES/Kinasa ligada a integrinas: papel en la progresión de la resistencia a la insulina y en el desarrollo de la obesidad/; info:eu-repo/grantAgreement/MINECO/Acción estratégica de Salud 2013-2016//ES/PI20%2F00634; info:eu-repo/grantAgreement/CAM//S2017%2FBMD-3751/ES/ENFERMEDAD RENAL CRÓNICA. NUEVAS ESTRATEGIAS PARA LA PREVENCIÓN, DIAGNÓSTICO Y TRATAMIENTO/; info:eu-repo/grantAgreement/MINECO/PN de I+D+I/RD12%2F0021%2F0006/ES/Enfermedades Renales/; info:eu-repo/grantAgreement/MINECO/ISCIII/RD16%2F0009%2F0018/ES/Red de Investigacion Renal REDINREN/; de Frutos, S., Griera, M., Hatem-Vaquero, M. et al. The integrin beta1 modulator Tirofiban prevents adipogenesis and obesity by the overexpression of integrin-linked kinase: a pre-clinical approach in vitro and in vivo. Cell Biosci 12, 10 (2022).; http://hdl.handle.net/10017/50868Test; AR/0000037821; Cell and Bioscience; 12; 18; 10

الإتاحة: https://doi.org/10.1186/s13578-022-00746-1Test
http://hdl.handle.net/10017/50868Test

المؤلفون: García Marin, Javier, Vaquero López, Juan José, Rodríguez Puyol, Diego María

المساهمون: Universidad de Alcalá. Departamento de Medicina y Especialidades Médicas, Universidad de Alcalá. Departamento de Química Orgánica y Química Inorgánica

مصطلحات موضوعية: Integrin-linked kinase, ILK, Cpd22, Molecular dynamics, PELE, Pseudokinase, Química, Chemistry

وصف الملف: application/pdf

العلاقة: Journal of Computer-Aided Molecular Design, 2022, v. 36, n. 8, p. 575-589; http://hdl.handle.net/10017/53951Test; AR/0000041942; Journal of Computer-Aided Molecular Design; 36; 589; 575

الإتاحة: https://doi.org/10.1007/s10822-022-00466-1Test
http://hdl.handle.net/10017/53951Test

المؤلفون: Wang, SC, Makino, K, Xia, WY, Kim, JS, Im, SA, Peng, H, Mok, SC, Singletary, SE, Hung, MC

المساهمون: 임석아, Im, SA

مصطلحات موضوعية: INTEGRIN-LINKED KINASE, EPITHELIAL OVARIAN-CANCER, PHOSPHOINOSITIDE-3-OH KINASE, ACTIVATION, EXPRESSION, CLONING, DOMAIN, B/AKT, GENE, ILK, DOC-2/hDab-2, anoikis, breast cancer, HER-2, neu

العلاقة: Oncogene, Vol.20 No.47, pp.6960-6964; 158763; https://hdl.handle.net/10371/179215Test; 000171641000018; 2-s2.0-0035909524

الإتاحة: https://doi.org/10.1038/sj.onc.1204873Test
https://hdl.handle.net/10371/179215Test

المؤلفون: Paul C. McDonald, Shoukat Dedhar

المصدر: Cancers; Volume 14; Issue 13; Pages: 3209

مصطلحات موضوعية: integrin-linked kinase, cell signaling, invasion, colonization, metastasis, cell plasticity, epithelial mesenchymal transition, neutrophil extracellular trap, therapeutic resistance

وصف الملف: application/pdf

العلاقة: Tumor Microenvironment; https://dx.doi.org/10.3390/cancers14133209Test

الإتاحة: https://doi.org/10.3390/cancers14133209Test

المؤلفون: Miguel A. Ortega, Chen Chaowen, Oscar Fraile-Martinez, Cielo García-Montero, Miguel A. Saez, Iris Cruza, Claude Pereda-Cerquella, Miguel Angel Alvarez-Mon, Luis G. Guijarro, Yuliia Fatych, César Menor-Salván, Melchor Alvarez-Mon, Juan De Leon-Luis, Julia Buján, Natalio Garcia-Honduvilla, Coral Bravo, Angel Asúnsolo-del-Barco

المصدر: Journal of Personalized Medicine; Volume 12; Issue 2; Pages: 277

مصطلحات موضوعية: chronic venous disease (CVD), pregnancy, integrin-linked kinase (ILK), cadherins, cell behavior, extracellular matrix (ECM)

وصف الملف: application/pdf

العلاقة: Mechanisms of Diseases; https://dx.doi.org/10.3390/jpm12020277Test

الإتاحة: https://doi.org/10.3390/jpm12020277Test

المؤلفون: Condello, Salvatore, Prasad, Mayuri, Atwani, Rula, Matei, Daniela

المساهمون: Obstetrics and Gynecology, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Tissue transglutaminase, Integrin-linked kinase, Fibronectin, Integrin β1, β-catenin, Wnt signaling, Ovarian cancer

وصف الملف: application/pdf

العلاقة: Journal of Biological Chemistry; Condello S, Prasad M, Atwani R, Matei D. Tissue transglutaminase activates integrin-linked kinase and β-catenin in ovarian cancer. J Biol Chem. 2022;298(8):102242. doi:10.1016/j.jbc.2022.102242; https://hdl.handle.net/1805/34808Test

الإتاحة: https://doi.org/10.1016/j.jbc.2022.102242Test
https://hdl.handle.net/1805/34808Test