المؤلفون: Johan Wouters, Manon Mirgaux, Laurence Leherte

المصدر: Mirgaux, M, Leherte, L & Wouters, J 2020, ' Influence of the presence of the heme cofactor on the JK-loop structure in indoleamine-2,3-dioxygenase-1 ', Acta crystallographica. Section D: Structural Biology, vol. 76, pp. 1211-1221 . https://doi.org/10.1107/S2059798320013510Test

مصطلحات موضوعية: 3-dioxygenase-1, Stereochemistry, Heme, Crystal structure, Crystallography, X-Ray, 010402 general chemistry, Molecular Dynamics, 01 natural sciences, Cofactor, Substrate Specificity, 03 medical and health sciences, chemistry.chemical_compound, Molecular dynamics, Structural Biology, Catalytic Domain, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, Indoleamine 2,3-dioxygenase, tryptophan metabolism, 030304 developmental biology, 0303 health sciences, Binding Sites, cancer immunotherapy, biology, Chemistry, JK-loop conformation, Substrate (chemistry), Active site, 0104 chemical sciences, Loop (topology), biology.protein, human indoleamine-2,3-dioxygenase-1, human indoleamine-2

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab1aea99978399e7909dd482461b2abdTest
https://pure.unamur.be/ws/files/53018589/publi_ido.pdfTest

المؤلفون: Peyraud, Florent

المساهمون: Université de Bordeaux (UB), Antoine Italiano

المصدر: https://dumas.ccsd.cnrs.fr/dumas-03352840Test ; Sciences du Vivant [q-bio]. 2021.

مصطلحات موضوعية: Tryptophan metabolism, Immunotherapy, Immune checkpoint inhibitors, Predictive value, Mechanism of resistance, Indoleamine-2, 3-dioxygenase, Métabolisme du tryptophane, Kynurénine, Immunothérapie, Inhibiteur de checkpoint inhibiteur, Facteur prédictif, Mécanisme de résistance, [SDV]Life Sciences [q-bio], [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

العلاقة: dumas-03352840; https://dumas.ccsd.cnrs.fr/dumas-03352840Test; https://dumas.ccsd.cnrs.fr/dumas-03352840/documentTest; https://dumas.ccsd.cnrs.fr/dumas-03352840/file/Med_Spe_2021_Peyraud.pdfTest

الإتاحة: https://dumas.ccsd.cnrs.fr/dumas-03352840Test
https://dumas.ccsd.cnrs.fr/dumas-03352840/documentTest
https://dumas.ccsd.cnrs.fr/dumas-03352840/file/Med_Spe_2021_Peyraud.pdfTest

المؤلفون: Silvia Mezi, Simone Scagnoli, Alessio Cortellini, Andrea Botticelli, Bruna Cerbelli, Marianna Nuti, Ilaria Grazia Zizzari, Luana Lionetto, Maurizio Simmaco, Raffaele Giusti, Edoardo Cerbelli, Paolo Marchetti, Michela Roberto, Giulia Pomati

المصدر: Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)

مصطلحات موضوعية: 0301 basic medicine, Male, Programmed Cell Death 1 Receptor, indoleamine-2, Gastroenterology, Metastasis, 0302 clinical medicine, Renal cell carcinoma, Neoplasms, Odds Ratio, Medicine, Immunology and Allergy, Prospective cohort study, Immune Checkpoint Inhibitors, Original Research, Aged, 80 and over, education.field_of_study, Hazard ratio, Tryptophan, indoleamine-2,3-dioxygenase, anti-pd-1, kynurenine, tryptophan metabolism, tumor immunity, Middle Aged, Prognosis, Primary tumor, Treatment Outcome, 3-dioxygenase, Female, Nivolumab, lcsh:Immunologic diseases. Allergy, medicine.medical_specialty, Population, Immunology, 03 medical and health sciences, Internal medicine, Cell Line, Tumor, Biomarkers, Tumor, Humans, education, Aged, Neoplasm Staging, business.industry, medicine.disease, Head and neck squamous-cell carcinoma, 030104 developmental biology, Drug Resistance, Neoplasm, Neoplasm Grading, business, lcsh:RC581-607, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11e33e0a00cd114f54002e90f341879Test
http://hdl.handle.net/11573/1434713Test

المؤلفون: Marcel Jenny, Sebastian Schröcksnadel, Florian Überall, Dietmar Fuchs

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.mdpi.com/1424-8247/3/8/2647/pdfTest/.

مصطلحات موضوعية: tryptophan, indoleamine-2, 3-dioxygenase, Δ9-tetrahydrocannabinol, cannabidiolPharmaceuticals 2010, 3 2648

العلاقة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.429.7260Test; http://www.mdpi.com/1424-8247/3/8/2647/pdfTest/

الإتاحة: http://www.mdpi.com/1424-8247/3/8/2647/pdfTest/

المؤلفون: Christiane A. Opitz, Adam J. Rose, Ines Heiland, Saskia Trump, Michael Platten, Joram Mooiweer, Melanie Keil, Dyah L. Dewi, Soumya R. Mohapatra, Bianca Berdel, Jana K. Sonner, Isabell Adam, Kathrin Thedieck, Ahmed Sadik

المصدر: OncoImmunology, 7(12):1486353. Taylor & Francis Group
OncoImmunology, Vol 7, Iss 12 (2018)
Oncoimmunology

مصطلحات موضوعية: 0301 basic medicine, lcsh:Immunologic diseases. Allergy, ARYL-HYDROCARBON RECEPTOR, tumor, tRNA synthetase, AMINO-ACID TRANSPORTER, inflammation and cancer, proliferation, Immunology, cancer metabolism, immunosurveillance, Activating Transcription Factor 4, Indoleamine-2, TRANSLATIONAL CONTROL, lcsh:RC254-282, 03 medical and health sciences, tryptophan-2, 0302 clinical medicine, Downregulation and upregulation, nutrients, MAMMALIAN-CELLS, Protein biosynthesis, Immunology and Allergy, Initiation factor, tryptophan, Indoleamine 2,3-dioxygenase, INDOLEAMINE 2, Original Research, GENE-EXPRESSION, RESPONSE PATHWAY, immunosuppression, Kinase, Chemistry, ATF4, starvation, TUMORAL IMMUNE RESISTANCE, EPITHELIAL-CELLS, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Cell biology, 030104 developmental biology, 3-dioxygenase, Oncology, 030220 oncology & carcinogenesis, T-CELLS, Phosphorylation, Indoleamine-2, 3-dioxygenase, lcsh:RC581-607, INDOLEAMINE 2,3-DIOXYGENASE

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d850db9c0fda85f070d5c186bb8378Test
https://research.rug.nl/en/publications/5a66a80a-9fd2-4ca7-a2f4-5150526fd88bTest

المؤلفون: Barbara Wirleitner A, Gabriele Neurauter A, Markus Nagl C, Dietmar Fuchs A

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: https://www.i-med.ac.at/imcbc/molecularcellbiologyfolder/pdf/wirleitner_trpinvitro2004.pdfTest.

مصطلحات موضوعية: Taurine chloramine, Interferon-, Indoleamine-2, 3 dioxygenase, Neopterin

وصف الملف: application/pdf

العلاقة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.579.4580Test

المؤلفون: Abhishek Thakur, Firoz abdul Samad, Syed Hussain Basha

المصدر: Bioinformation

مصطلحات موضوعية: 0301 basic medicine, HOMO, LUMO, Molecular model, Stereochemistry, Indoleamine-2, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, Carboranes, Indoleamine 2,3-dioxygenase, chemistry.chemical_classification, Anti-cancer, molecular modeling, 010405 organic chemistry, Withaferin-A, General Medicine, Hypothesis, Ligand (biochemistry), molecular dynamic simulations, 0104 chemical sciences, 3-dioxygenase, 030104 developmental biology, Enzyme, chemistry, Docking (molecular), Withaferin A, docking, Carborane, immunotherapy, Macromolecule

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85e7a56e19ea7ad213fe5d9d4c561fbTest
https://doi.org/10.6026/97320630012374Test

المؤلفون: Korte-Bouws, Gerdien A.H., Albers, Eline, Voskamp, Marije, Hendriksen, Hendrikus, de Leeuw, Lidewij R., Güntürkün, Onur, de Roock, Sytze, Vastert, Sebastiaan J., Korte, S. Mechiel, Afd Pharmacology, Pharmacology

المساهمون: Afd Pharmacology, Pharmacology

المصدر: Pharmaceuticals
Volume 12
Issue 1
Pharmaceuticals, 12(1). Multidisciplinary Digital Publishing Institute
Pharmaceuticals, 12(9). MDPI AG
Pharmaceuticals, Vol 12, Iss 1, p 9 (2019)

مصطلحات موضوعية: musculoskeletal diseases, medicine.medical_specialty, Indoleamine-2,3-dioxygenase (IDO), 3-dioxygenase (IDO), Phenylalanine, lcsh:Medicine, lcsh:RS1-441, Arthritis, Guanosinetriphosphate-Cyclohydrolase-1 (GTP-CH1), Pharmaceutical Science, Inflammation, Indoleamine-2, Neopterin, Article, Proinflammatory cytokine, lcsh:Pharmacy and materia medica, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Drug Discovery, Medicine, guanosinetriphosphate–cyclohydrolase-1 (GTP–CH1), Sickness behavior, Fatigue, Kynurenine, Tetrahydrobiopterin (BH4), 030203 arthritis & rheumatology, business.industry, lcsh:R, Tryptophan, Tetrahydrobiopterin, indoleamine-2,3-dioxygenase (IDO), medicine.disease, Endocrinology, chemistry, Tyrosine, Molecular Medicine, Animal studies, medicine.symptom, business, 030217 neurology & neurosurgery, Biomarkers, medicine.drug

وصف الملف: application/pdf; image/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56533f657cbb4c81022d73f837e2dbe6Test
https://doi.org/10.3390/ph12010009Test

المؤلفون: Paolo Puccetti, Claudia Feriotti, Luigina Romani, Carmine Vacca, Eliseu Frank de Araújo, Tania Alves da Costa, Flávio V. Loures, Vera Lúcia Garcia Calich

المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Immunology

مصطلحات موضوعية: 0301 basic medicine, Disease tolerance, T cell, Immunology, Inflammation, Biology, 3 dioxygenase, Indoleamine-2, ENZIMAS OXIRREDUTORAS, Microbiology, Proinflammatory cytokine, 03 medical and health sciences, 0302 clinical medicine, Pulmonary dendritic cells, Immunity, medicine, Immunology and Allergy, Indoleamine 2,3-dioxygenase, Pathogen, Indoleamine-2,3 dioxygenase, Paracoccidioidomycosis, Phosphorylated indoleamine-2,3 dioxygenase, Signaling function, indoleamine-2,3 dioxygenase, phosphorylated indoleamine-2,3 dioxygenase, Original Research, Phosphorylated indoleamine-2, Phenotype, 030104 developmental biology, medicine.anatomical_structure, Phosphorylation, medicine.symptom, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0b26f462e70a7a7443857304ebcb70Test
http://hdl.handle.net/11391/1425780Test

المؤلفون: Young-Seung Kim, Martin W. Brechbiel, Kwong Y. Tsang, Anna R. Kwilas, Massimo Fantini, Ravi A. Madan, James L. Gulley, Caroline Jochems, Christopher R. Heery, Robert C. Newton, Italia Grenga, Lauren M. Lepone, Jeffrey Schlom, Romaine I. Fernando, James W. Hodge, Renee N. Donahue

المصدر: Oncotarget

مصطلحات موضوعية: Lipopolysaccharides, Male, 0301 basic medicine, 3-dioxygenase (IDO), indoleamine-2, Lymphocyte Activation, 0302 clinical medicine, Oximes, Cytotoxic T cell, Medicine, Kynurenine, Sulfonamides, Tryptophan, hemic and immune systems, Middle Aged, Healthy Volunteers, Tumor antigen, Phenotype, Oncology, 030220 oncology & carcinogenesis, Female, Tumor necrosis factor alpha, Research Paper, Adult, T cells, chemical and pharmacologic phenomena, Tregs, Cancer Vaccines, Peripheral blood mononuclear cell, Interferon-gamma, Young Adult, 03 medical and health sciences, Immune system, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, dendritic cells, Aged, business.industry, Granulocyte-Macrophage Colony-Stimulating Factor, Cancer, Dendritic cell, medicine.disease, CTL, 030104 developmental biology, Immunology, Leukocytes, Mononuclear, Peptides, business, T-Lymphocytes, Cytotoxic, IDO inhibitor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1070afce2000de3f9372fe1029410bbeTest
https://doi.org/10.18632/oncotarget.9326Test