نتائج البحث - "disease heterogeneity"

41

The Identification of Novel Biomarkers Is Required to Improve Adult SMA Patient Stratification, Diagnosis and Treatment

المؤلفون: Paul Langard, Maria Grazia Biferi, Giorgia Querin, Piera Smeriglio

المساهمون: Institut de Myologie, Centre National de la Recherche Scientifique (CNRS)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Association française contre les myopathies (AFM-Téléthon)-Sorbonne Université (SU), Centre de Recherche en Myologie, Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Gestionnaire, Hal Sorbonne Université, Centre de recherche en Myologie – U974 SU-INSERM, Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Association française contre les myopathies (AFM-Téléthon)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Journal of Personalized Medicine
Journal of Personalized Medicine, MDPI, 2020, 10 (3), pp.75. ⟨10.3390/jpm10030075⟩
Journal of Personalized Medicine, 2020, 10 (3), pp.75. ⟨10.3390/jpm10030075⟩
Journal of Personalized Medicine, Vol 10, Iss 75, p 75 (2020)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe4a0a4ddace8260c28c6b82aa916dcTest
http://europepmc.org/articles/PMC7564782Test

42

Addressing heterogeneity in amyotrophic lateral sclerosis CLINICAL TRIALS

المؤلفون: Namita Goyal, Leonard H. van den Berg, Chaim Lebovits, Nathan P. Staff, Angela Genge, Yael Gothelf, Robert G. Miller, Robert H. Baloh, James D. Berry, Ralph Kern, Anthony J. Windebank, Merit Cudkowicz, Nicholas J. Maragakis

المصدر: Muscle & nerve, vol 62, iss 2
Muscle & Nerve

مصطلحات موضوعية: 0301 basic medicine, Oncology, amyotrophic lateral sclerosis, Outcome Assessment, Physiology, 030105 genetics & heredity, Medical and Health Sciences, 0302 clinical medicine, Outcome Assessment, Health Care, Medicine, Invited Reviews, Amyotrophic lateral sclerosis, Precision Medicine, Therapeutic strategy, Clinical Trials as Topic, Biological Variation, Physical Functional Performance, Prognosis, Transcranial Magnetic Stimulation, Respiratory Function Tests, Drug development, Disease Progression, Biomarker (medicine), Early phase, Clinical risk factor, medicine.medical_specialty, Population, Risk Assessment, outcome measures, 03 medical and health sciences, Cellular and Molecular Neuroscience, Drug Development, Physiology (medical), Internal medicine, Humans, Speech, Muscle Strength, Predictive biomarker, clinical trials, Invited Review, Neurology & Neurosurgery, business.industry, Amyotrophic Lateral Sclerosis, biomarkers, Reproducibility of Results, disease heterogeneity, medicine.disease, Health Care, Clinical trial, enrichment strategies, Biological Variation, Population, Neurology (clinical), business, 030217 neurology & neurosurgery, Biomarkers

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c74f4d197772468205516f9bb84437f0Test
https://pubmed.ncbi.nlm.nih.gov/31899540Test

43

Atrophy subtypes in prodromal Alzheimer's disease are associated with cognitive decline

المؤلفون: Philip Scheltens, Mara ten Kate, Wiesje M. van der Flier, Ellen Dicks, Betty M. Tijms, Charlotte E. Teunissen, Pieter Jelle Visser, Frederik Barkhof

المساهمون: Radiology and nuclear medicine, Amsterdam Neuroscience - Neurodegeneration, Neurology, NCA - neurodegeneration, APH - Personalized Medicine, APH - Methodology, Epidemiology and Data Science, Laboratory Medicine, Psychiatrie & Neuropsychologie, RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience

المصدر: Brain : a journal of neurology, 141(12), 3443-3456
Brain, 141, 3443-3456. Oxford University Press
ten Kate, M, Dicks, E, van der Flier, W M, Teunissen, C E, Barkhof, F, Scheltens, P, Tijms, B M & Alzheimer’s Disease Neuroimaging Initiative 2018, ' Atrophy subtypes in prodromal Alzheimer's disease are associated with cognitive decline ', Brain : a journal of neurology, vol. 141, no. 12, pp. 3443-3456 . https://doi.org/10.1093/brain/awy264Test

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, medicine.medical_specialty, Prodromal Symptoms, Disease, Disease cluster, non-negative matrix factorization, 03 medical and health sciences, mild cognitive impairment, 0302 clinical medicine, Atrophy, Alzheimer Disease, Internal medicine, medicine, Cluster Analysis, Humans, Dementia, HETEROGENEITY, Cognitive Dysfunction, BRAIN ATROPHY, Effects of sleep deprivation on cognitive performance, Cognitive decline, Aged, business.industry, Brain, Cognition, Original Articles, Middle Aged, Alzheimer's disease, IMPAIRMENT, disease heterogeneity, medicine.disease, Magnetic Resonance Imaging, NEUROIMAGING INITIATIVE ADNI, MODEL, 030104 developmental biology, Disease Progression, PATTERNS, Female, prognosis, Neurology (clinical), TRAJECTORIES, business, Biomarkers, 030217 neurology & neurosurgery, Alzheimer's Disease Neuroimaging Initiative

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc2f4b4d1fcd3d2512958bf3a0d5f6dTest
https://doi.org/10.1093/brain/awy264Test

44

Moving toward endotypes in atopic dermatitis: Identification of patient clusters based on serum biomarker analysis

المؤلفون: Eszter Csomor, DirkJan Hijnen, Matthew A. Sleeman, Barbara Giovannone, Ian Strickland, Carla A.F.M. Bruijnzeel-Koomen, Bret R. Sellman, Marjolein S. de Bruin-Weller, Julia Drylewicz, Judith L. Thijs, Stefan Nierkens, Athula Herath, Tomas Mustelin, Richard D. May

المصدر: Journal of Allergy and Clinical Immunology, 140(3), 730. Mosby Inc.

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Chemokine, Thymic stromal lymphopoietin, Immunology, Principal component analysis, Inflammation, Comorbidity, Disease, Immunoglobulin E, Unsupervised cluster analysis, Dermatitis, Atopic, Clusters, 030207 dermatology & venereal diseases, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Journal Article, medicine, Humans, Immunology and Allergy, Rhinitis, Atopic dermatitis, Body surface area, biology, business.industry, Endotypes, Allergens, medicine.disease, Personalized medicine, Asthma, Disease heterogeneity, Vascular endothelial growth factor, Phenotypes, 030104 developmental biology, chemistry, biology.protein, Cytokines, Female, medicine.symptom, business, Biomarkers

وصف الملف: image/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a5cdc33b8a7cc544b09f60de971d4cTest
https://doi.org/10.1016/j.jaci.2017.03.023Test

45

تقرير

Systems Medicine: from molecular features and models to the clinic in COPD

المؤلفون: Gomez-Cabrero, David, Menche, Jörg, Cano, Isaac, Abugessaisa, Imad, Huertas-Migueláñez, Mercedes, Tenyi, Akos, de Mas, Igor, Kiani, Narsis A, Marabita, Francesco, Falciani, Francesco, Burrowes, Kelly, Maier, Dieter, Wagner, Peter, Selivanov, Vitaly, Cascante, Marta, Roca, Josep, Barabási, Albert-László, Tegnér, Jesper

مصطلحات موضوعية: Chronic diseases, COPD, Disease heterogeneity, Systems Medicine, Predictive Modeling, Co-morbidity

العلاقة: http://www.translational-medicine.com/content/12/S2/S4Test

الإتاحة: http://www.translational-medicine.com/content/12/S2/S4Test

View record in BASE

46

Clinical and genetic correlates of islet-autoimmune signatures in juvenile-onset type 1 diabetes

المؤلفون: Laura A. Claessens, Flip Mulder, Joris Wesselius, Bart O. Roep, Henk-Jan Aanstoot, Dick Mul, Bobby P. C. Koeleman, Menno van Lummel, Tanja Nikolic, Sandra Laban

المصدر: Diabetologia

مصطلحات موضوعية: 0301 basic medicine, Male, Endocrinology, Diabetes and Metabolism, T-Lymphocytes, Autoimmunity, Disease, medicine.disease_cause, 0302 clinical medicine, Autoreactive T cells, Genotype, Autoimmune disease, Insulin, Child, Principal Component Analysis, geography.geographical_feature_category, biology, Precision medicine, Islet, Patient heterogeneity, Disease heterogeneity, medicine.anatomical_structure, Child, Preschool, Female, Immunotherapy, Adult, Adolescent, T cell, 030209 endocrinology & metabolism, Islet autoantigen, Major histocompatibility complex, Article, 03 medical and health sciences, Young Adult, HLA-DQ Antigens, Internal Medicine, medicine, Humans, Protein Precursors, Disease endotypes, Cell Proliferation, Retrospective Studies, Type 1 diabetes, geography, business.industry, HLA-DR Antigens, Epitope spreading, medicine.disease, 030104 developmental biology, Cross-Sectional Studies, Diabetes Mellitus, Type 1, Immunology, biology.protein, Personalised medicine, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46570700d2046750f60dc91295dbf29eTest
https://pubmed.ncbi.nlm.nih.gov/31754749Test

47

Therapies for prion diseases

المؤلفون: Saima Zafar, Aneeqa Noor, Inga Zerr

المصدر: Amsterdam [u.a.] : Elsevier, Handbook of Clinical Neurology 165, 47-58 (2019). doi:10.1016/B978-0-444-64012-3.00004-6
Psychopharmacology of Neurologic Disease / Zafar, Saima ; : Elsevier, 2019, ; ISSN: 00729752 ; ISBN: 9780444640123 ; doi:10.1016/B978-0-444-64012-3.00004-6

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, drug therapy [Creutzfeldt-Jakob Syndrome], PrPSc Proteins, Survival, media_common.quotation_subject, diagnosis [Creutzfeldt-Jakob Syndrome], Disease, therapeutic use [Quinine], 03 medical and health sciences, Presentation, analogs & derivatives [Quinine], PrP(Sc), 0302 clinical medicine, pathology [Brain], methods [Clinical Trials as Topic], mental disorders, medicine, Animals, Humans, ddc:610, Intensive care medicine, therapeutic use [Sulfonylurea Compounds], media_common, drug therapy [Prion Diseases], Quinine, business.industry, therapeutic use [Anti-Bacterial Agents], Therapeutic trial, diagnosis [Prion Diseases], nervous system diseases, Disease heterogeneity, Anti-Bacterial Agents, Clinical trial, 030104 developmental biology, Sulfonylurea Compounds, Prion, Therapy, business, 030217 neurology & neurosurgery