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61دورية أكاديمية
المؤلفون: Martin, Thomas, Hajek, Roman, Moreau, Philippe, Augustson, Bradley, Castro, Nelson, Pika, Tomas, Delimpasi, Sosana, de la Rubia, Javier, Maiolino, Angelo, Reiman, Anthony, Martinez-Lopez, Joaquin, Mikhael, Joseph, Yong, Kwee, Risse, Marie-Laure, Casca, France, Marion, Sylvia, Macé, Sandrine, Dimopoulos, Meletios A.
المصدر: Clinical Lymphoma Myeloma and Leukemia ; volume 22, page S178 ; ISSN 2152-2650
مصطلحات موضوعية: Cancer Research, Oncology, Hematology
الإتاحة: https://doi.org/10.1016/s2152-2650Test(22)01095-3
https://api.elsevier.com/content/article/PII:S2152265022010953?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2152265022010953?httpAccept=text/plainTest -
62دورية أكاديمية
المؤلفون: Martin, Thomas, Hajek, Roman, Moreau, Philippe, Augustson, Bradley, Castro, Nelson, Pika, Tomas, Delimpasi, Sosana, de la Rubia, Javier, Maiolino, Angelo, Reiman, Anthony, Martinez-Lopez, Joaquin, Mikhael, Joseph, Yong, Kwee, Risse, Marie-Laure, Casca, France, Marion, Sylvia, Macé, Sandrine, Dimopoulos, Meletios A.
المصدر: Clinical Lymphoma Myeloma and Leukemia ; volume 22, page S411-S412 ; ISSN 2152-2650
مصطلحات موضوعية: Cancer Research, Oncology, Hematology
الإتاحة: https://doi.org/10.1016/s2152-2650Test(22)01601-9
https://api.elsevier.com/content/article/PII:S2152265022016019?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2152265022016019?httpAccept=text/plainTest -
63دورية أكاديمية
المؤلفون: Solves, Pilar, Tur, Susana, Gómez-Seguí, Inés, Viel, María, Eiris, Juan, Planells, Yolanda, Rodríguez, Raquel, Peñalver, Isabel, Castro, Emma, de la Rubia, Javier
المصدر: Transfusion and Apheresis Science ; volume 61, issue 3, page 103342 ; ISSN 1473-0502
مصطلحات موضوعية: Hematology
الإتاحة: https://doi.org/10.1016/j.transci.2021.103342Test
https://api.elsevier.com/content/article/PII:S1473050221003505?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1473050221003505?httpAccept=text/plainTest -
64دورية أكاديمية
المؤلفون: Mingot Castellano, María Eva, Pascual Izquierdo, Cristina, González, Ataulfo, Viejo Llorente, Aurora, Valcarcel Ferreiras, David, Sebastián, Elena, García Candel, Faustino, Sarmiento Palao, Héctor, Gómez Seguí, Inés, de la Rubia, Javier, Cid, Joan, Martínez Nieto, Jorge, Hernández Mateo, Luis, Goterris Viciedo, Rosa, Fidalgo, Teresa, Salinas, Ramon, del Rio-Garma, Julio
المصدر: Medicina Clínica ; volume 158, issue 12, page 630.e1-630.e14 ; ISSN 0025-7753
مصطلحات موضوعية: General Medicine
الإتاحة: https://doi.org/10.1016/j.medcli.2021.03.040Test
https://api.elsevier.com/content/article/PII:S0025775321003328?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0025775321003328?httpAccept=text/plainTest -
65دورية أكاديمية
المؤلفون: Maia, Catarina, Puig, Noemí, Cedena, Maria-Teresa, Gutiérrez, Norma, Calassanz, María-J, Martín-Ramos, Maria-L, Garcia, Miguel Teodoro Hernandez, Rosiñol, Laura, González, Mª Esther, de la Fuente, Felipe de Arriba, Oriol, Albert, González, Verónica, Escalante, Fernando, De la Rubia, Javier, Mesa, Mercedes Gironella, Ríos, Rafael, García-Sánchez, Ricarda, Arguiñano, José-M, Alegre, Adrián, San-Miguel, Jesus, Palacios, Juan José Lahuerta, Blade, Joan, Niesvizky, Ruben, Mateos, María-Victoria, Paiva, Bruno
المصدر: Clinical Lymphoma Myeloma and Leukemia ; volume 22, page S84-S85 ; ISSN 2152-2650
مصطلحات موضوعية: Cancer Research, Oncology, Hematology
الإتاحة: https://doi.org/10.1016/s2152-2650Test(22)00420-7
https://api.elsevier.com/content/article/PII:S2152265022004207?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2152265022004207?httpAccept=text/plainTest -
66دورية أكاديمية
المؤلفون: Palacios, Juan José Lahuerta, Ubieto, Ana Jiménez, Rosiñol, Laura, Paiva, Bruno, López, Joaquín Martinez, Cedena, María Teresa, Puig, Noemí, Ríos, Rafael, Oriol, Albert, Blanchard, María Jesús, Bargay, Joan, Martín, Jesús, martinez, Rafael, Sureda, Anna, De la Rubia, Javier, Hernández, Miguel teodoro, Cabañas, Valentín, krsnik, Isabel, Palomera, Luis, Casado, Felipe, Gonzalez-Montes, Yolanda, de la Fuente, Felipe de Arriba, Mateos, María-Victoria, San-Miguel, Jesus, Blade, Joan
المصدر: Clinical Lymphoma Myeloma and Leukemia ; volume 22, page S24-S25 ; ISSN 2152-2650
مصطلحات موضوعية: Cancer Research, Oncology, Hematology
الإتاحة: https://doi.org/10.1016/s2152-2650Test(22)00313-5
https://api.elsevier.com/content/article/PII:S2152265022003135?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2152265022003135?httpAccept=text/plainTest -
67دورية أكاديمية
المؤلفون: Villalba, Ana, Lloret, Pilar, Rodríguez, Ana Pilar González, Arzuaga-Méndez, Javier, Puig, Noemí, Arnao, Mario, Arguiñano, José María, Jiménez, María, Canet, Marta, Teruel, Ana I., Sola, María, Díaz, Francisco J., Encinas, Cristina, García, Antonio, Rosiñol, Laura, Suárez, Alexia, González, Marta Sonia, Izquierdo, Isabel, Hernández, Miguel Teodoro, Infante, María Stefania, Sánchez, María José, Sampol, Antonia, De la Rubia, Javier
المصدر: Clinical Lymphoma Myeloma and Leukemia ; volume 22, page S158 ; ISSN 2152-2650
مصطلحات موضوعية: Cancer Research, Oncology, Hematology
الإتاحة: https://doi.org/10.1016/s2152-2650Test(22)00554-7
https://api.elsevier.com/content/article/PII:S2152265022005547?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2152265022005547?httpAccept=text/plainTest -
68دورية أكاديمية
المؤلفون: Ghobrial, Irene M., Rodríguez-Otero, Paula, Koh, Youngil, Martínez-López, Joaquín, Parmar, Gurdeep, Prince, Miles, Quach, Hang, de la Rubia, Javier, Hermansen, Emil, Hungria, Vania, Kalayoglu Besisik, Sevgi, Kim, Jin Seok, Leleu, Xavier, Peceliunas, Valdas, Schjesvold, Fredrik, Dubin, Franck, Devisme, Christine, Lepine, Lucie, Macé, Sandrine, Oprea, Corina, Mateos, María-Victoria
المصدر: Clinical Lymphoma Myeloma and Leukemia ; ISSN 2152-2650
مصطلحات موضوعية: Cancer Research, Oncology, Hematology
الإتاحة: https://doi.org/10.1016/j.clml.2022.03.011Test
https://api.elsevier.com/content/article/PII:S2152265022000994?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2152265022000994?httpAccept=text/plainTest -
69دورية أكاديمية
المؤلفون: Alameda, Daniel, Goicoechea, Ibai, Vicari, Marco, Arriazu, Elena, Nevone, Alice, Rodriguez, Sara, Lasa, Marta, Puig, Noemi, Cedena, Maria Teresa, Alignani, Diego, Garate, Sonia, Lara-Astiaso, David, Vilas-Zornoza, Amaia, Sarvide, Sarai, Ocio, Enrique M, Lecumberri, Ramon, Garcia de Coca, Alfonso, Labrador, Jorge, Gonzalez, Maria-Esther, Palomera, Luis, Gironella, Mercedes, Cabañas, Valentin, Casanova, Maria, Oriol, Albert, Krsnik, Isabel, Perez-Montaña, Albert, de la Rubia, Javier, de la Puerta, Jose-Enrique, de Arriba, Felipe, Fazio, Vito Michele, Martinez-Lopez, Joaquin, Lahuerta, Juan-Jose, Mateos, Maria-Victoria, Odero, Maria-Dolores, Prosper, Felipe, Weiner, Assaf, Amit, Ido, Nuvolone, Mario, San Miguel, Jesus F, Paiva, Bruno
المساهمون: Alameda, Daniel, Goicoechea, Ibai, Vicari, Marco, Arriazu, Elena, Nevone, Alice, Rodriguez, Sara, Lasa, Marta, Puig, Noemi, Cedena, Maria Teresa, Alignani, Diego, Garate, Sonia, Lara-Astiaso, David, Vilas-Zornoza, Amaia, Sarvide, Sarai, Ocio, Enrique M, Lecumberri, Ramon, Garcia de Coca, Alfonso, Labrador, Jorge, Gonzalez, Maria-Esther, Palomera, Lui, Gironella, Mercede, Cabañas, Valentin, Casanova, Maria, Oriol, Albert, Krsnik, Isabel, Perez-Montaña, Albert, de la Rubia, Javier, de la Puerta, Jose-Enrique, de Arriba, Felipe, Fazio, Vito Michele, Martinez-Lopez, Joaquin, Lahuerta, Juan-Jose, Mateos, Maria-Victoria, Odero, Maria-Dolore, Prosper, Felipe, Weiner, Assaf, Amit, Ido, Nuvolone, Mario, San Miguel, Jesus F, Paiva, Bruno
مصطلحات موضوعية: Adult, Human, Immunoglobulin Light-chain Amyloidosi, Multiple Myeloma, Plasma Cell, Tumor Cells, Cultured, Transcriptome
الوصف: Although light-chain amyloidosis (AL) and multiple myeloma (MM) are characterized by tumor plasma cell (PC) expansion in bone marrow (BM), their clinical presentation differs. Previous attempts to identify unique pathogenic mechanisms behind such differences were unsuccessful, and no studies have investigated the differentiation stage of tumor PCs in patients with AL and MM. We sought to define a transcriptional atlas of normal PC development in secondary lymphoid organs (SLOs), peripheral blood (PB), and BM for comparison with the transcriptional programs (TPs) of tumor PCs in AL, MM, and monoclonal gammopathy of undetermined significance (MGUS). Based on bulk and single-cell RNA sequencing, we observed 13 TPs during transition of normal PCs throughout SLOs, PB, and BM. We further noted the following: CD39 outperforms CD19 to discriminate newborn from long-lived BM-PCs; tumor PCs expressed the most advantageous TPs of normal PC differentiation; AL shares greater similarity to SLO-PCs whereas MM is transcriptionally closer to PB-PCs and newborn BM-PCs; patients with AL and MM enriched in immature TPs had inferior survival; and protein N-linked glycosylation-related TPs are upregulated in AL. Collectively, we provide a novel resource to understand normal PC development and the transcriptional reorganization of AL and other monoclonal gammopathies.
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34133718; info:eu-repo/semantics/altIdentifier/wos/WOS:000747506600010; volume:138; issue:17; firstpage:1583; lastpage:1589; numberofpages:7; journal:BLOOD; https://hdl.handle.net/11571/1467229Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85117749922; https://ashpublications.org/blood/article/138/17/1583/476203/Tumor-cells-in-light-chain-amyloidosis-and-myelomaTest
الإتاحة: https://doi.org/10.1182/blood.2020009754Test
https://hdl.handle.net/11571/1467229Test
https://ashpublications.org/blood/article/138/17/1583/476203/Tumor-cells-in-light-chain-amyloidosis-and-myelomaTest -
70دورية أكاديمية
المؤلفون: Dimopoulos, Meletios A., Moreau, Philippe, Augustson, Bradley, Castro, Nelson, Pika, Tomas, Delimpasi, Sosana, De la Rubia, Javier, Maiolino, Angelo, Reiman, Tony, Martinez‐Lopez, Joaquin, Martin, Thomas, Mikhael, Joseph, Yong, Kwee, Risse, Marie‐Laure, Asset, Gaelle, Marion, Sylvia, Hajek, Roman
المصدر: American Journal of Hematology; Jan2023, Vol. 98 Issue 1, pE15-E19, 5p