المؤلفون: A. N. Goryainova, M. A. Antsupova, E. R. Samitova, N. V. Loba, V. V. Koroid, M. A. Churnosova, O. I. Elfimova, N. V. Koroid, N. E. Kuzina, I. N. Zakharova, А. Н. Горяйнова, М. А. Анцупова, Э. Р. Самитова, Н. В. Лобань, В. В. Короид, М. А. Чурносова, О. И. Елфимова, Н. В. Короид, Н. Е. Кузина, И. Н. Захаров

المصدر: Meditsinskiy sovet = Medical Council; № 1 (2024); 254–268 ; Медицинский Совет; № 1 (2024); 254–268 ; 2658-5790 ; 2079-701X

مصطلحات موضوعية: неотложная терапия, bronchoobstructive syndrome, symptoms, clinic, emergency therapy, бронхообструктивный синдром, симптомы, клиника

الوصف: Plastic bronchitis is a rare disease. Despite the fact that the clinical signs of plastic bronchitis were first described by Galen more than 1800 years ago, the pathogenesis of the disease remains poorly understood to this day. As a result, it is not always possible to choose a therapy that allows for complete clinical and laboratory remission or complete recovery of the patient. Treatment of plastic bronchitis should be multifaceted, including the appointment of medications, hardware and physiotherapy methods. Despite the increasing relevance of the topic, the number of published works dealing with the problems of plastic bronchitis, both in world literature and domestic, is small. This review presents historical information on the study of plastic bronchitis, discusses the pathogenesis of the disease, taking into account the results of research over the past decades, lists the main and secondary clinical signs and symptoms, discusses the principles of modern therapy, including both invasive and non-invasive, physiotherapy, and treatment methods. As a clinical example, a case of plastic bronchitis in a 3-year-old boy who was treated in the intensive care unit and then in the infectious diseases department of the Z.A. Bashlyaeva State Clinical Hospital with a diagnosis of Idiopathic plastic bronchitis during one of the relapses of the disease from March 7, 2020 to March 22, 2020 is given. The diagnosis was previously made at the Morozov City Clinical Hospital. ; Пластический бронхит относится к редким заболеваниям. Несмотря на то что клинические признаки пластического бронхита впервые были описаны Галеном более 1800 лет назад, патогенез болезни до настоящего времени остается малоизученным, вследствие этого не всегда удается подобрать терапию, позволяющую добиться полной клинико-лабораторной ремиссии или полного выздоровления больного. В клиническую картину пластического бронхита входит большой ряд симптомов, главным (эксклюзивным) клиническим признаком пластического бронхита, без которого его диагноз невозможен, ...

وصف الملف: application/pdf

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الإتاحة: https://doi.org/10.21518/ms2024-014Test
https://doi.org/10.1136/thx.15.4.325Test
https://doi.org/10.1183/16000617.0096-2021Test
https://doi.org/10.1136/bmj.2.2010.69-aTest
https://doi.org/10.26442/26586630.2020.3.200348Test
https://doi.org/10.1002/ppul.10179Test
https://doi.org/10.1097/ALN.0000000000003381Test
https://doi.org/10.1002/phar.1290Test
https://doi.org/10.2169/internalmedicine.8137-16Test
https://doi.org/10.1183/09031936.96.09030612Test

المؤلفون: Igor V. Leshchenko, Natalia A. Esaulova, Tatyana V. Glushkova, Sergey N. Skornyakov

المصدر: Терапевтический архив, Vol 95, Iss 3, Pp 203-209 (2023)

مصطلحات موضوعية: post-covid-19 syndrome, respiratory disorders, virus-induced bronchoobstructive syndrome, dlco, Medicine

الوصف: Aim. Assess the functional state of trespiratory system and effectiveness of therapeutic tactics for broncho-obstructive syndrome (BOS) in patients in the post-COVID period. Materials and methods. A two-center cohort prospective study included 10 456 and 89 patients, respectively. A comprehensive assessment of the respiratory system included clinical, laboratory and functional data, spirometry, body plethysmography, and a study of diffusive capacity of the lungs (DLCO). Therapy consisted of budesonide suspension or fixed combination beclomethasone dipropionate/formoterol (EMD BDP/FORM). Results. The frequency of BOS in the cohort was 72% (7497 patients). In 13% (n=974) of cases, bronchial asthma was diagnosed for the first time, in 4.4% (n=328) chronic obstructive pulmonary disease. Risk factors for the development and decrease in DLCO in the post-COVID period were identified. In the group of complex instrumental examination of lung function, the absence of violations of spirometric data and indicators determined by body plethysmography was determined. Conclusion. Risk factors for BOS in post-COVID period are atopy, a history of frequent acute respiratory infections, smoking, blood eosinophilia, moderate and severe forms of COVID-19. The advantage of a fixed combination of EMD BDP/FORM in MART mode compared with nebulized suspension budesonide + solution of salbutamol in treatment of BOS was shown. Risk factors for DLCO disorders were established: severe COVID-19, hospitalization in the intensive care unit, the need for additional oxygen therapy.

وصف الملف: electronic resource

العلاقة: https://ter-arkhiv.ru/0040-3660/article/viewFile/340913/118439Test; https://doaj.org/toc/0040-3660Test; https://doaj.org/toc/2309-5342Test

الوصول الحر: https://doaj.org/article/7943c5c253e24219a38a8167bceea307Test

المؤلفون: Azimova K.T, Garifulina L.M.

المصدر: JOURNAL OF CARDIORESPIRATORY RESEARCH 2023, Volume-4(Issue-2)

مصطلحات موضوعية: bronchoobstructive syndrome, bronchiolitis, cytokines, bronchitis, relapse, protective function

الوصف: To date in the pathology of childhood respiratory diseases occupies the first place, having a significant impact on infant mortality and the formation of persistent abnormalities in child health, among which a significant role belongs to bronchiolitis whose frequency depends on the period of the year, place of residence, epidemiological situation. As you know, the leading role in the formation and recurrence of many diseases of the bronchopulmonary system is given to inflammation of the respiratory tract. Therefore, the study of various mediators of inflammation allows us to clarify the nature and type of the inflammatory process and thus opens up great opportunities for assessing the severity and predicting the further course of the disease.

العلاقة: https://zenodo.org/record/8115079Test; https://doi.org/10.5281/zenodo.8115079Test; oai:zenodo.org:8115079

الإتاحة: https://doi.org/10.5281/zenodo.8115079Test
https://doi.org/10.5281/zenodo.8115078Test
https://zenodo.org/record/8115079Test

المؤلفون: Colmán Gómez, Deisy Beatriz, Oviedo Ramírez, Shirley Rocío, Cantero Noguera, Cielos Jemima, Cordone Ramos, Alba María

المصدر: Discover Medicine; Vol. 7 No. 2 (2023): DM; 67-74 ; Discover Medicine; Vol. 7 Núm. 2 (2023): DM; 67-74 ; 2521-5612 ; 2521-2273 ; 10.2300/dm.v7i2

مصطلحات موضوعية: Síndrome broncobstructivo, Pediatría, Signos y Síntomas, Manejo de la Vía Aérea, Bronchoobstructive Syndrome, Paediatrics, Signs and Symptoms, Airway Management

الوصف: Background: This study focuses on the analysis of Bronchial Obstructive Syndrome (BOS) in children hospitalised in 2019 at the Hospital de Clínicas. Specific data reveal a significant incidence of paediatric BBS, pointing to the need to understand its epidemiological, clinical and therapeutic aspects. Objective: To determine the approach to obstructive bronchial syndrome in paediatric patients hospitalised at the Hospital de Clínicas in 2019. Materials and Methods: A retrospective observational design was used. The sample included paediatric patients with a diagnosis of OBS in 2019, data collected from March to May 2023. Inclusion/exclusion criteria were rigorously applied. Measurement instruments such as patient charts were used to collect detailed data. Results: The results revealed a prominent prevalence in children under 2 years of age (80.5%), with prominent respiratory symptoms (51.3% respiratory distress). The association with underlying pathologies was notable (46.2%). Common treatment included oxygen therapy (76.9%) and salbutamol (97.4%). Conclusion: This detailed analysis underlines patterns consistent with the literature, highlighting the need for specific preventive strategies for children under 2 years of age. Furthermore, it highlights the importance of individualising the management of paediatric OBS, taking into account underlying pathologies and variability in clinical presentation. ; Introducción: Este estudio se centra en el análisis del Síndrome Bronquial Obstructivo (SBO) en niños hospitalizados en 2019 en el Hospital de Clínicas. Datos específicos revelan una importante incidencia de SBO pediátrico, señalando la necesidad de comprender sus aspectos epidemiológicos, clínicos y terapéuticos. Objetivo: Determinar el abordaje del síndrome bronquial obstructivo en pacientes pediátricos hospitalizados en el Hospital de Clínicas durante el año 2019 Materiales y Métodos: Se empleó un diseño observacional retrospectivo. La muestra incluyó pacientes pediátricos con diagnóstico de SBO en 2019, datos ...

وصف الملف: application/pdf

العلاقة: https://revistascientificas.una.py/index.php/DM/article/view/3948/3197Test; https://revistascientificas.una.py/index.php/DM/article/view/3948Test

الإتاحة: https://doi.org/10.2300/dm.v7i2Test
https://revistascientificas.una.py/index.php/DM/article/view/3948Test

المؤلفون: Лим , Максим, Шавази, Nurali

المصدر: International Journal of Scientific Pediatrics; Vol. 2 No. 11 (2023): november; 398-400 ; Международный журнал научной педиатрии; Том 2 № 11 (2023): ноябрь; 398-400 ; Xalqaro ilmiy pediatriya jurnali; Nashr soni. 2 No. 11 (2023): noyabr; 398-400 ; 2181-2926

مصطلحات موضوعية: бронхообструктивный синдром, предикторы, дети, bronchoobstructive syndrome, predictors, children, bronxoobstruktiv sindrom, bashorat qiluvchilar, bolalar

الوصف: Purpose of the study: to determine the significance of risk factors for the development of recurrent bronchial obstruction in children. Material and methods of research. A total of 240 children were examined and divided into 3 groups: Group I - patients with acute obstructive bronchitis (AOB), acute bronchiolitis (ABL), Group II - children with recurrent obstructive bronchitis (ROB) and bronchial asthma (BA), Group III - patients with acute bronchitis without bronchial obstruction (BA). To assess the significance of risk factors for the development of recurrent and relapsing course of BOS, we analysed genealogical, biological and social anamnesis, premorbid and family background, in children of the studied groups, characterising the state of family health and features of child development in the ante- and postnatal periods, as well as in the first years of the child's life. Results of the study and discussion. When studying the causes and factors influencing the development and course of BOS in children, the most important is the study of background diseases that aggravate and prolong the course of bronchial obstruction. The study of pre-mobilisation background in patients of the compared groups showed that a number of factors were significantly more frequent in patients with acute and recurrent course of bronchobstructive syndrome. Conclusions. It was found that the risk factors for the development of recurrent course of bronchial obstruction in children are: artificial feeding (P<0.002; OR=4.80), rickets (P<0.02; OR=2.15), overweight (P<0.002; OR=5.40), atopy (P<0.001; OR=18.32), first episode of BOS before the age of 1 year (P<0.002; OR=3.01), absence of fever (P<0.002; OR=12.95) and catarrhal syndrome (P<0.001; OR=60.0) during the episode of illness. ; Абстракт. Цель исследования: определить значимость факторов риска развития рецидивирующей бронхиальной обструкции у детей. Материал и методы исследования. Обследовано 240 детей, которые разделены на 3 группы: I группа - больные ...

وصف الملف: application/pdf

العلاقة: https://ijsp.uz/index.php/journal/article/view/179/160Test; https://ijsp.uz/index.php/journal/article/view/179Test

الإتاحة: https://doi.org/10.56121/2181-2926-2023-2-11-398-400Test
https://ijsp.uz/index.php/journal/article/view/179Test

المؤلفون: Шавази , Нурали, Лим, Максим

المصدر: International Journal of Scientific Pediatrics; Vol. 2 No. 11 (2023): november; 401-404 ; Международный журнал научной педиатрии; Том 2 № 11 (2023): ноябрь; 401-404 ; Xalqaro ilmiy pediatriya jurnali; Nashr soni. 2 No. 11 (2023): noyabr; 401-404 ; 2181-2926

مصطلحات موضوعية: бронхообструктивный синдром, модифицированная бронхофонография, дети, bronchoobstructive syndrome, modified bronchophonography, children, бронхообструктив синдром, модификацияланган бронхофонография, болалар

الوصف: Purpose of the study: to establish the diagnostic and prognostic significance of modified bronchophonography in bronchobstructive syndrome in children. Material and methods of research. The paper presents the results of examinations of children with bronchoobstructive syndrome. The patients were divided into 3 groups of 60 patients: Group I - patients with acute obstructive bronchitis (AOB), acute bronchiolitis (ABL), Group II - children with recurrent obstructive bronchitis (ROB) and bronchial asthma (BA), Group III - patients with acute bronchitis without bronchial obstruction (BA). Results of the study and discussion. Analysis of modified bronchophonography indices in groups I-II showed that on admission, E:I index>1.6 indicating bronchial obstruction of the II degree (P<0.001). On the 2nd day of observation, E:I index significantly decreased in patients with ROB, BA and was significantly lower in comparison with indices of patients with OOB, OBL (P<0,05). On the 3rd day of observation and at discharge, the indices were relatively equal, no significant difference was observed (P>0.2; P>0.1). When constructing the ROC-curve and analysing the curve coordinates, it was found that in determining the risk of ROB and AD in children, the diagnostic significance of the E:I index≥1.78, with a sensitivity of 71.7% and specificity of 61.1%. Conclusions. The values of E:I index≥1.78 are predictors of the risk of ROS and BA development, the diagnostic significance of which is confirmed by high sensitivity and specificity, which can be recommended for detecting the risk of recurrent course of BOS in children. ; Аннотация. Цель исследования: yстановить диагностическую и прогностическую значимость модифицированной бронхофонографии при бронхообструктивном синдроме у детей. Материал и методы исследования. В работе представлены результаты обследований детей с бронхообструктивным синдромом. Больные были разделены на 3 группы по 60 больных: I группа - пациенты c острым обструктивным бронхитом (ООБ), ...

وصف الملف: application/pdf

العلاقة: https://ijsp.uz/index.php/journal/article/view/180/158Test; https://ijsp.uz/index.php/journal/article/view/180Test

الإتاحة: https://doi.org/10.56121/2181-2926-2023-2-11-401-404Test
https://ijsp.uz/index.php/journal/article/view/180Test

المؤلفون: I. V. Leshchenko, N. A. Esaulova, И. В. Лещенко, Н. А. Эсаулова

المساهمون: The authors express their gratitude to the administration and staff of the pulmonological service of the “Novaya bol’nitsa” Clinical Association Limited Liability Companies for their assistance, aid and support in conducting this scientific study., Авторы выражают благодарность администрации и сотрудникам пульмонологической службы Общества с ограниченной ответственностью «Медицинское объединение “Новая больница”» за содействие, помощь и поддержу в проведении данного научного исследования.

المصدر: PULMONOLOGIYA; Том 32, № 4 (2022); 539-547 ; Пульмонология; Том 32, № 4 (2022); 539-547 ; 2541-9617 ; 0869-0189

مصطلحات موضوعية: лечение, postcovid period, bronchoobstructive syndrome, risk factors, treatment, постковидный период, бронхообструктивный синдром, факторы риска

الوصف: It is hard to make a conclusion about relationship between Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) and Bronchoobstructive Syndrome (BOS) in the postcovid period based on the literature.The aim. To determine the optimal treatment approaches by conducting a comprehensive assessment of clinical, laboratory and functional parameters, taking into account the risk factors for the development of BOS.Methods. 10,456 patients with Coronavirus Disease-19 (COVID-19) were examined, and 7,459 patients were randomized into 2 groups with a newly diagnosed BOS. Group 1 (n = 3,245) was prescribed beclomethasone/formoterol (BDP/FORM) as Maintenance And Reliever Therapy (MART). Group 2 (n = 4,252) was prescribed budesonide suspension (BUD) and salbutamol solution (SAL). The study assessed severity of COVID-19, presence of atopy and frequency of acute respiratory viral infections (SARS) in the medical history, spirometric parameters, blood eosinophils, Asthma Control Questionnaire-5 (ACQ-5) score, use of pro re nata medications, and adverse events.Results. Patients who had mild COVID-19 were diagnosed with BOS at weeks 8 – 24 (73.3%), while patients with moderate or severe COVID-19 were diagnosed at week 4 (54.9%). Virus-induced BOS (VI BOS) was diagnosed in 71.8% of the cases. 13% of the patients with BOS in postcovid period were diagnosed with asthma.Conclusion. The incidence of BOS is significantly higher in patients with atopy and history of frequent SARS who had moderate or severe COVID-19. A fixed combination of extrafine BDP/FORM as MART was superior to nebulized BUD + SALM in the treatment of VI BOS. ; По данным литературы, о взаимосвязи Severe Acute Respiratory Syndrome CoronaVirus-2 (SARS-CoV-2) и бронхообструктивного синдрома (БОС) в постковидном периоде однозначного вывода сделать невозможно.Целью исследования являлось определение оптимальных подходов к лечению на основании комплексной оценки клинических, лабораторных и функциональных показателей с учетом факторов риска развития БОС.Материалы и ...

وصف الملف: application/pdf

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الإتاحة: https://doi.org/10.18093/0869-0189-2022-32-4-539-547Test
https://doi.org/10.1016/B978-1-4557-3383-5.00041-5Test
https://doi.org/10.1001/archinte.158.22.2453Test
https://doi.org/10.4049/jimmunol.1002456Test
https://doi.org/10.4049/jimmunol.169.10.5458Test
https://doi.org/10.1016/j.anai.2010.09.010Test
https://doi.org/10.1016/j.jaci.2004.09.025Test
https://doi.org/10.1016/s0022-3476Test(87)80295-0
https://doi.org/10.1001/jama.2020.6775Test
https://doi.org/10.1016/S2213-2600Test(21)00031-X

المؤلفون: Yu.K. Bolbot, K.K. Hodiatska

المصدر: Zdorovʹe Rebenka, Vol 14, Iss 4, Pp 218-224 (2019)

مصطلحات موضوعية: young children, bronchoobstructive syndrome, vitamin D, supplementation, Pediatrics, RJ1-570

الوصف: Background. Acute obstructive bronchitis (AOB) ranks second among the respiratory diseases in children. In recent years, the results of clinical studies demonstrate a correlation between the low level of vitamin D (VD) and the risk of recurrent respiratory infections in adults and children. At the same time, the impact of VD insufficiency/deficiency and timely compensation of these changes on the frequency and severity of broncho-obstructive syndrome (BOS) in young children remains poorly understood. Thus, the purpose of the research was to study the features of VD level in young children with recurrent BOS and the efficacy of vitamin D3 supplementation on incidence and severity of the disease. Materials and methods. We examined 120 children with acute obstructive bronchitis. Group I included 60 patients with episodic BOS (up to 3 episodes per year), group II consisted of 60 children with recurrent BOS (3 or more episodes per year). The control group represented 30 healthy children of the corresponding age. We evaluated the severity of BOS and determined the serum level of 25-hydroxyvitamin D (25(OH)D) using an electrochemiluminescence method. Subsequently, the group of children with recurrent BOS was divided into two subgroups: IIa subgroup included 30 children who received vitamin D3 1000 IU daily throughout the year, IIb included 30 patients who were not supplemented with VD. The effectiveness of vitamin D3 supplementation was determined by the changes in the blood level of 25(OH)D, frequency and severity of BOS episodes. We used non-parametric methods for statistical analysis of data. For all types of analysis, the critical value of the significance level (p) was taken to be < 0.05. Results. The analysis of the clinical features of BOS episode showed that in the group of children with recurrent BOS compared to patients with episodic BOS the disease was characterized by a more severe course (23.3 % vs. 10.0 %, respectively; p = 0.034). We found that the mean VD level in children with recurrent BOS was 13.68 (7.96; 19.51) ng/ml and in children with episodic BOS 33.0 (28.19, 41.97) ng/ml (p < 0.001). The VD supplementation in the group with recurrent BOS was significantly lower than in children who were ill episodically (5 % vs. 60 %; p

وصف الملف: electronic resource

العلاقة: http://childshealth.zaslavsky.com.ua/article/view/174034Test; https://doaj.org/toc/2224-0551Test; https://doaj.org/toc/2307-1168Test

الوصول الحر: https://doaj.org/article/c6803b0d1d544b75a6ba01012b6e5b23Test

المؤلفون: Зубаренко, О., Весілик, Н., Гурієнко, К.

المصدر: Bukovinian Medical Herald; Vol. 15 No. 4(60) (2011); 176-179 ; Буковинский медицинский вестник; Том 15 № 4(60) (2011); 176-179 ; Буковинський медичний вісник; Том 15 № 4(60) (2011); 176-179 ; 2413-0737 ; 1684-7903

مصطلحات موضوعية: діти, бронхообструктивний синдром, психовегетативний статус, дети, бронхообструктивный синдром, психовегетативный статус, children, bronchoobstructive syndrome, psycho-vegetative status

الوصف: The diseases of the respiratory organs rank first in the pattern of children‟s morbidity. In order to evaluate psycho-vegetative correlations in children with acute obstructive bronchitis the authors examined 111 patients aged from 7 to 14 years with this particular pathology, undergoing inpatient treatment at the pulmonological department. Derangements of the vegetative balance and psychological characteristics were detected. Such factors as the presence of a high level of anxiety, initial vagotonia, asympathicotonic reactivity in children afflicted with acute obstructive bronchitis prognostically unfavourable factors in. ; В структуре заболеваемости детей болезни органов дыхания занимают первое место. Для определения психовегетативных соотношений у детей при остром обструктивном бронхите обследовано 111 пациентов с данной патологией в возрасте от 7 до 14 лет, которые находились на стационарном лечении в пульмонологическом отделении. Обнаружены сдвиги вегетативного баланса и психологических характеристик, где наличие высокого уровня тревожности, исходной ваготонии, асимпатикотонической реактивности у детей, больных острым обструктивным бронхитом, является прогностически неблагоприятными факторами. ; У структурі захворюваності дітей хвороби органів дихання посідають перше місце. Для визначення психовегетативних співвідношень у дітей при гострому обструктивному бронхіті було обстежено 111 пацієнтів із даною патологією віком від 7 до 14 років, що перебували на стаціонарному лікуванні в пульмонологічному відділенні. Виявлені зрушення вегетативного балансу та психологічних характеристик, де наявність високого рівня тривожності, вихідної вагототонії, асимпатикотонічної реактивності в дітей, хворих на гострий обструктивний бронхіт, є прогностично несприятливими факторами.

وصف الملف: application/pdf

العلاقة: http://e-bmv.bsmu.edu.ua/article/view/231413/230400Test; http://e-bmv.bsmu.edu.ua/article/view/231413Test

الإتاحة: http://e-bmv.bsmu.edu.ua/article/view/231413Test

المؤلفون: V. Sokolovskaya V., A. Grekova I., В. Соколовская В., А. Грекова И.

المصدر: CHILDREN INFECTIONS; Том 19, № 1 (2020); 17-20 ; ДЕТСКИЕ ИНФЕКЦИИ; Том 19, № 1 (2020); 17-20 ; 2072-8107 ; 10.22627/2072-8107-2020-19-1

مصطلحات موضوعية: respiratory syncytial viral infection, morbidity, children, bronchoobstructive syndrome, immunity, респираторно-синцитиальная вирусная инфекция, заболеваемость, дети, бронхообструктивный синдром, иммунитет

الوصف: Acute respiratory infections (ARI) consistently occupy a leading place in the structure of infectious pathology, especially among children. The spectrum of pathogens is usually determined by the season and age aspect of the observed. In a large number of respiratory viruses, respiratory syncytial virus (RSV) occupies a special place due to the variety and severity of clinical manifestations of the disease caused by it in young children. This article is devoted to the analysis of the clinical course of RSV infection in children, the study of the features of the immune status against the background of this disease.It was found that in most cases of RSV infection in children was characterized by signs of bronchial obstruction syndrome and as a consequence in this group of children were found to have dysfunction of the immune system and reduction in the total number of T-lymphocytes, the hyperactivation In-cell component of adaptive immunity, manifested disimmunoglobulinemia (increase in the content of total IgE at lower IgA and IgG), that is, with the formation of immunodeficiency states from T- and B-cell links of adaptive immunity, with long-term recovery of impaired performance, even against the background of effective antiviral therapy. ; Острые респираторные инфекции (ОРИ) неизменно занимают ведущее место в структуре инфекционной патологии, особенно среди детей. Спектр возбудителей, как правило, обусловлен сезоном и возрастным аспектом наблюдаемых. В многочисленном ряду респираторных вирусов, респираторно-синцитиальный вирус (РСВ) занимает особое место в связи с многообразием и тяжестью клинических проявлений вызываемой им болезни у детей раннего возраста. Данная статья посвящена анализу клинического течения РСВ инфекции у детей, изучению особенностей иммунного статуса на фоне данного заболевания.Было установлено, что в большинстве случаев РСВ инфекция у детей протекала с признаками бронхообструктивного синдрома и как следствие у данной группы детей была выявлена дисфункция иммунной системы в виде снижения ...

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الإتاحة: https://doi.org/10.22627/2072-8107-2020-19-1-17-20Test
https://doi.org/10.22627/2072-8107-2020-19-1Test
https://detinf.elpub.ru/jour/article/view/477Test