المؤلفون: Jerold Chun, Gwendolyn E. Kaeser

المصدر: Frontiers in Genetics
Frontiers in Genetics, Vol 11 (2020)

مصطلحات موضوعية: 0301 basic medicine, lcsh:QH426-470, Disease, amyloid precursor protein, Genetic recombination, Pathogenesis, 03 medical and health sciences, 0302 clinical medicine, somatic gene recombination, gencDNA, mental disorders, Amyloid precursor protein, Genetics, Gene, Genetics (clinical), biology, Mechanism (biology), amyloid cascade hypothesis, Reverse transcriptase, Biochemistry of Alzheimer's disease, lcsh:Genetics, 030104 developmental biology, mosaicism, 030220 oncology & carcinogenesis, Perspective, biology.protein, Molecular Medicine, APP, Alzheimer’s disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6f7d5f94526a6db7b049ab55a5d2d7Test
https://pubmed.ncbi.nlm.nih.gov/32457796Test

المؤلفون: Walter H. Backes, Frans R.J. Verhey, Jacobus F.A. Jansen, Inge C.M. Verheggen, M.P.J. van Boxtel

المصدر: Neuroscience and Biobehavioral Reviews. 90:26-33

مصطلحات موضوعية: 0301 basic medicine, Amyloid beta, Cognitive Neuroscience, Central nervous system, Blood–brain barrier, BETA-PEPTIDE, Imaging, 03 medical and health sciences, Behavioral Neuroscience, 0302 clinical medicine, Cerebrospinal fluid, SMALL VESSEL DISEASE, Interstitial space, CEREBROSPINAL-FLUID, Interstitial fluid, Alzheimer Disease, medicine, Humans, A-BETA, Blood-brain barrier, Aquaporin 4, biology, Chemistry, DEMENTIA, CENTRAL-NERVOUS-SYSTEM, Brain, MOUSE MODEL, Alzheimer's disease, TRANSPORT, ALZHEIMERS-DISEASE, Kinetics, 030104 developmental biology, Neuropsychology and Physiological Psychology, medicine.anatomical_structure, AMYLOID CASCADE HYPOTHESIS, biology.protein, Glymphatic system, Clearance, Amyloid-beta, Neuroscience, BBB, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f02c3a0c7689bf091d8ad2d5c372a2Test
https://doi.org/10.1016/j.neubiorev.2018.03.028Test

المصدر: Neuroscience and Biobehavioral Reviews. 90:26-33

مصطلحات موضوعية: DEMENTIA, CENTRAL-NERVOUS-SYSTEM, MOUSE MODEL, Alzheimer's disease, BETA-PEPTIDE, TRANSPORT, Imaging, ALZHEIMERS-DISEASE, SMALL VESSEL DISEASE, CEREBROSPINAL-FLUID, AMYLOID CASCADE HYPOTHESIS, Glymphatic system, Clearance, Amyloid-beta, BBB, A-BETA, Blood-brain barrier

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=od________83::9a611ac59e3dd42b92c350256cc69eb0Test
https://cris.maastrichtuniversity.nl/en/publications/98bfeb58-0983-4cf5-92e9-693591eaf667Test

المؤلفون: Hasegawa Shin, Gotoh Leo, Taguchi Masayuki, Ogomori Koji, Kawasaki Hiroaki

مصطلحات موضوعية: Alzheimer's disease, Amyloid β protein (Aβ)-induced toxicity, Amyloid cascade hypothesis, Orexin, Dual orexin receptor antagonist (DORA), Suvorexant

وصف الملف: application/pdf

العلاقة: https://fukuoka-u.repo.nii.ac.jp/?action=repository_uri&item_id=5208Test; http://id.nii.ac.jp/1316/00005197Test/; 福岡大学医学紀要 = Medical Bulletin of Fukuoka University, 48(1), 49-55(2021-03); AN00216390; https://fukuoka-u.repo.nii.ac.jp/?action=repository_action_common_download&item_id=5208&item_no=1&attribute_id=22&file_no=1Test

الإتاحة: https://fukuoka-u.repo.nii.ac.jp/?action=repository_uri&item_id=5208Test
http://id.nii.ac.jp/1316/00005197Test/
https://fukuoka-u.repo.nii.ac.jp/?action=repository_action_common_download&item_id=5208&item_no=1&attribute_id=22&file_no=1Test

المؤلفون: Rashid, Maha H

المصدر: Senior Independent Study Theses

مصطلحات موضوعية: Alzheimer’s Disease, Aβ, Default Mode Network, Hypometabolism, Retrosplenial Cortes, Amyloid Cascade Hypothesis, Neuroscience, Molecular and Cellular Neuroscience, Other Neuroscience and Neurobiology

وصف الملف: application/pdf

العلاقة: https://openworks.wooster.edu/independentstudy/8744Test; https://openworks.wooster.edu/cgi/viewcontent.cgi?article=11016&context=independentstudyTest

الإتاحة: https://openworks.wooster.edu/independentstudy/8744Test
https://openworks.wooster.edu/cgi/viewcontent.cgi?article=11016&context=independentstudyTest

المؤلفون: Fertan, Emre

مصطلحات موضوعية: Alzheimer's disease, Amyloid cascade hypothesis, Beta-amyloid, Disease models, Single-molecule detection, Soluble aggregates, Super-resolution imaging

الإتاحة: https://doi.org/10.17863/cam.108416Test
https://www.repository.cam.ac.uk/handle/1810/368077Test

المؤلفون: Francesco Morena, Ilaria Tortorella, Chiara Argentati, Sabata Martino, Martina Bazzucchi, Carla Emiliani

المصدر: Journal of Personalized Medicine, Vol 10, Iss 115, p 115 (2020)
Journal of Personalized Medicine

مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, energetic metabolism, glucose metabolism, Type-3-Diabetes, lcsh:Medicine, Medicine (miscellaneous), Inflammation, Review, Disease, Bioinformatics, adipose tissue dysfunction, neuroinflammation, Pathogenesis, 03 medical and health sciences, 0302 clinical medicine, medicine, lysosomes dysfunction, Neuroinflammation, business.industry, amyloid cascade hypothesis, lcsh:R, Metabolic disorder, Neurodegeneration, neurodegeneration, Lipid metabolism, medicine.disease, 030104 developmental biology, medicine.symptom, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318ddb7e9eb4c16b1fe0dbe632694642Test
https://doi.org/10.3390/jpm10030115Test

المؤلفون: Yashin, Anatoliy I, Fang, Fang, Kovtun, Mikhail, Wu, Deqing, Duan, Matt, Arbeev, Konstantin, Akushevich, Igor, Kulminski, Alexander, Culminskaya, Irina, Zhbannikov, Ilya, Yashkin, Arseniy, Stallard, Eric, Ukraintseva, Svetlana

المصدر: Exp Gerontol ; ISSN:1873-6815 ; Volume:107

مصطلحات موضوعية: Amyloid cascade hypothesis, BBB, Cancer, Diabetes, Neurodegeneration, Neuroinflammation, Neuronal death, Pleiotropy, Response to infection, Synapse loss

العلاقة: https://doi.org/10.1016/j.exger.2017.10.020Test; https://pubmed.ncbi.nlm.nih.gov/29107063Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920782Test/

الإتاحة: https://doi.org/10.1016/j.exger.2017.10.020Test
https://pubmed.ncbi.nlm.nih.gov/29107063Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920782Test/

المؤلفون: Gandini A, Bartolini M, Tedesco D, Martinez-Gonzalez L, Roca C, Campillo NE, Zaldivar-Diez J, Perez C, Zuccheri G, Miti A, Feoli A, Castellano S, Petralla S, Monti B, Rossi M, Moda F, Legname G, Martinez A, Bolognesi ML

المصدر: Journal of medicinal chemistry 61 (2018): 7640–7656. doi:10.1021/acs.jmedchem.8b0061010.1021/acs.jmedchem.8b00610
info:cnr-pdr/source/autori:Gandini A, Bartolini M, Tedesco D, Martinez-Gonzalez L, Roca C, Campillo NE, Zaldivar-Diez J, Perez C, Zuccheri G, Miti A, Feoli A, Castellano S, Petralla S, Monti B, Rossi M, Moda F, Legname G, Martinez A, Bolognesi ML/titolo:Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3 beta and Tau-Aggregation Inhibitors/doi:10.1021%2Facs.jmedchem.8b0061010.1021%2Facs.jmedchem.8b00610/rivista:Journal of medicinal chemistry/anno:2018/pagina_da:7640/pagina_a:7656/intervallo_pagine:7640–7656/volume:61

مصطلحات موضوعية: ASSAY INTERFERENCE COMPOUNDS, AMYLOID CASCADE HYPOTHESIS, TARGET-DIRECTED LIGANDS, BLOOD-BRAIN-BARRIER, GSK-3-BETA INHIBITORS, DRUG DISCOVERY, NEURODEGENERATIVE DISEASES, ACTIVITY PROFILES, COMPOUNDS PAINS, PROTEIN-TAU

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=cnr_________::9cce7dd9e5c7b60c33c184ab24673788Test

المؤلفون: Michiko Konno, 金野 倫子

المصدر: 日大医学雑誌 / Journal of Nihon University Medical Association. 2012, 71(6):379