المؤلفون: Nancy H.C. Loos, Irene A. Retmana, Jamie Rijmers, Yaogeng Wang, Changpei Gan, Maria C. Lebre, Rolf W. Sparidans, Jos H. Beijnen, Alfred H. Schinkel

المصدر: Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115304- (2023)

مصطلحات موضوعية: Adagrasib, KRASG12C inhibitor, ABCB1/P-glycoprotein, ABCG2/Breast cancer resistance protein, Cytochrome P450 3A, Carboxylesterase 1, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S0753332223010958Test; https://doaj.org/toc/0753-3322Test

الوصول الحر: https://doaj.org/article/d1dc8905ed1b43a4a3acf85b155c81d5Test

المؤلفون: Cian O’Leary, Grace Murphy, Yong Yeung, Ming Tang, Vikram Jain, Connor G O’Leary

المصدر: Cancers, Vol 15, Iss 23, p 5582 (2023)

مصطلحات موضوعية: NSCLC, KRAS, targeted therapy, sotorasib, adagrasib, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/2072-6694/15/23/5582Test; https://doaj.org/toc/2072-6694Test

الوصول الحر: https://doaj.org/article/61dbf7a4c323437985f77d9f4f507f45Test

المؤلفون: Yuchen Zhang, Cheukfai Li, Chenglai Xia, Keneth Kin Wah To, Zhixing Guo, Chongyang Ren, Lingzhu Wen, Fang Wang, Liwu Fu, Ning Liao

المصدر: Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-16 (2022)

مصطلحات موضوعية: Adagrasib (MRTX849), Multidrug resistance, ABC transporters, KRAS mutation, Cancer chemotherapy, Medicine, Cytology, QH573-671

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1478-811XTest

الوصول الحر: https://doaj.org/article/47ba05d7ed3f4389a67fd08e06ade868Test

المؤلفون: Ji J, Wang C, Fakih M

المصدر: OncoTargets and Therapy, Vol Volume 15, Pp 747-756 (2022)

مصطلحات موضوعية: krasg12c, sotorasib, adagrasib, colorectal cancer, targeted therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/targeting-krasg12c-mutated-advanced-colorectal-cancer-research-and-cli-peer-reviewed-fulltext-article-OTTTest; https://doaj.org/toc/1178-6930Test

الوصول الحر: https://doaj.org/article/83b4e05b3f1148b286b4813d966412a4Test

المؤلفون: Prakash Kulkarni, Atish Mohanty, Sravani Ramisetty, Herbert Duvivier, Ajaz Khan, Sagun Shrestha, Tingting Tan, Amartej Merla, Michelle El-Hajjaoui, Jyoti Malhotra, Sharad Singhal, Ravi Salgia

المصدر: Biomolecules, Vol 13, Iss 11, p 1587 (2023)

مصطلحات موضوعية: KRAS mutation, drug resistance, non-genetic mechanisms, sotorasib, adagrasib, Microbiology, QR1-502

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/2218-273X/13/11/1587Test; https://doaj.org/toc/2218-273XTest

الوصول الحر: https://doaj.org/article/2fb06324c434450dabc396224a13cca1Test

المؤلفون: Kruithof, Paul D, de Beer, Yvo M, Gulikers, Judith L, Stolk, Leo M L, Hendriks, Lizza E L, Croes, Sander, van Geel, Robin M J M

المصدر: Kruithof , P D , de Beer , Y M , Gulikers , J L , Stolk , L M L , Hendriks , L E L , Croes , S & van Geel , R M J M 2023 , ' Validated extended multiplexed LC-MS/MS assay for the quantification of adagrasib and sotorasib in human plasma, together with four additional SMIs ' , Journal of chromatography. B, Analytical technologies in the biomedical and life sciences , vol. 1231 , no. 1 , 123918 . https://doi.org/10.1016/j.jchromb.2023.123918Test

مصطلحات موضوعية: Adagrasib, Non-Small Cell Lung Cancer, Pharmacokinetics, Sotorasib, Validation

العلاقة: https://cris.maastrichtuniversity.nl/en/publications/b53c21bc-3f8f-44e2-9d83-94cfc8af2b91Test

الإتاحة: https://doi.org/10.1016/j.jchromb.2023.123918Test
https://cris.maastrichtuniversity.nl/en/publications/b53c21bc-3f8f-44e2-9d83-94cfc8af2b91Test

المؤلفون: Izabela Chmielewska, Paweł Krawczyk, Anna Grenda, Magdalena Wójcik-Superczyńska, Natalia Krzyżanowska, Michał Gil, Janusz Milanowski

المصدر: Cancers; Volume 15; Issue 14; Pages: 3732

مصطلحات موضوعية: KRAS gene, PD-L1, immunotherapy, non-small cell lung cancer, sotorasib, adagrasib

وصف الملف: application/pdf

العلاقة: Cancer Therapy; https://dx.doi.org/10.3390/cancers15143732Test

الإتاحة: https://doi.org/10.3390/cancers15143732Test

المؤلفون: Éabha O’Sullivan, Anna Keogh, Brian Henderson, Stephen P. Finn, Steven G. Gray, Kathy Gately

المصدر: Cancers; Volume 15; Issue 6; Pages: 1635

مصطلحات موضوعية: KRAS, G12C mutation, NSCLC, IMAs, sotorasib, adagrasib, drug resistance, BRAF, ACOX2

وصف الملف: application/pdf

العلاقة: Cancer Therapy; https://dx.doi.org/10.3390/cancers15061635Test

الإتاحة: https://doi.org/10.3390/cancers15061635Test

المؤلفون: Sahar F. Bannoura, Husain Yar Khan, Asfar S. Azmi

المصدر: Frontiers in Oncology, Vol 12 (2022)

مصطلحات موضوعية: KRAS, KRAS G12C, KRAS G12D, sotorasib, adagrasib, MRTX1133, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fonc.2022.1013902/fullTest; https://doaj.org/toc/2234-943XTest

الوصول الحر: https://doaj.org/article/bf8d5909f59d4a7ab5eb5fdc2beb73ecTest

المؤلفون: Albert K. Kwan, Gary A. Piazza, Adam B. Keeton, Caio A. Leite

المصدر: Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-23 (2022)

مصطلحات موضوعية: KRASG12C, Cancer, Clinical trial, Direct RAS inhibitor, Sotorasib, Adagrasib, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1756-9966Test

الوصول الحر: https://doaj.org/article/a9615ec9bc634026bc11a210feb232f3Test