المؤلفون: Veettil, Sachin K. Thekke, Zheng, Yuxi, Acosta, Uwe Hernandez, Wicaksono, Damar, Hecht, Michael

مصطلحات موضوعية: Mathematics - Numerical Analysis

الوصف: We address classic multivariate polynomial regression tasks from a novel perspective resting on the notion of general polynomial $l_p$-degree, with total, Euclidean, and maximum degree being the centre of considerations. While ensuring stability is a theoretically known and empirically observable limitation of any computational scheme seeking for fast function approximation, we show that choosing Euclidean degree resists the instability phenomenon best. Especially, for a class of analytic functions, we termed Trefethen functions, we extend recent argumentations that suggest this result to be genuine. We complement the novel regression scheme, presented herein, by an adaptive domain decomposition approach that extends the stability for fast function approximation even further.

الوصول الحر: http://arxiv.org/abs/2212.11706Test

المؤلفون: Sheng, Wancheng, Zhang, Qinglong, Zheng, Yuxi

مصطلحات موضوعية: Mathematics - Numerical Analysis

الوصف: In this paper, we propose a direct Eulerian generalized Riemann problem (GRP) scheme for a blood flow model in arteries. It is an extension of the Eulerian GRP scheme, which is developed by Ben-Artzi, et. al. in J. Comput. Phys., 218(2006). By using the Riemann invariants, we diagonalize the blood flow system into a weakly coupled system, which is used to resolve rarefaction wave. We also use Rankine-Hugoniot condition to resolve the local GRP formulation. We pay special attention to the acoustic case as well as the sonic case. The extension to the two dimensional case is carefully obtained by using the dimensional splitting technique. We test that the derived GRP scheme is second order accuracy.

الوصول الحر: http://arxiv.org/abs/2103.02224Test

المؤلفون: Zhang, Qinglong, Sheng, Wancheng, Zheng, Yuxi

مصطلحات موضوعية: Mathematics - Analysis of PDEs, Mathematical Physics

الوصف: The Riemann problem of one dimensional shallow water equations with discontinuous topography has been constructed recently. The elementary waves include shock waves, rarefaction waves, and the stationary wave. The stationary wave appears when the water depth changes, especially when there exists a bottom step. In this paper, we are mainly concerned with the interaction between a stationary wave with either a shock wave or a rarefaction wave. By using the characteristic analysis methods, the evolution of waves is described during the interaction process. The solution in large time scale is also presented in each case. The results may contribute to research on more complicated wave interaction problems.

الوصول الحر: http://arxiv.org/abs/2103.00886Test

المؤلفون: Rongmei LIU, Shuaibin LIU, Quanshun ZHENG, Yuxi BAI, Xuzhu ZHAO, Changwei NIU, Shunli SHI, Guoping ZHOU

المصدر: Zhongguo quanke yixue, Vol 25, Iss 30, Pp 3810-3816 (2022)

مصطلحات موضوعية: child health, adolescent, seated position, sitting position, vision screening, health management, zhengzhou, Medicine

الوصف: Background The prevalence of health problems in Chinese children and adolescents is high. The mention of myopia, obesity, caries, scoliosis and other health problems in adolescents in the Healthy China 2030 Initiative Indicates that these problems have become the national concerns. The establishment of a long-term, standardized disease screening and management mode by the community health center (CHC) in combination with schools in service coverage areas of the CHC will provide a new idea for strengthening the health management of children and adolescents by the CHC. Objective To perform posture assessment and vision screening in full-time students receiving the nine-year compulsory education in schools in the service coverage area of Chaohe Community Health Center of Zhengzhou Economic-Technological Development Area using a CHC-school-based approach, to identify problems in disease screening and management for children and adolescents, to analyze the practice and advantages of CHC-school-based disease screening and management, and to develop a CHC-school-based health management model for children and adolescents. Methods This study was conducted from May to November 2021. Cluster sampling was used to select grades 1-9 full-time students (n=11 318) in 225 classes of 6 primary schools and 3 middle schools in the areas covered with health services delivered by the Chaohe Community Health Center of Zhengzhou Economic-Technological Development Area. All of them received posture assessment and vision screening. Results Among the participants, 6 260 were male and 5 058 were female; 7 979 were pupils, and 3 339 were junior high school students. The prevalence of abnormal posture was 41.34% (4 679/11 318) . With the increase of grade, the prevalence of uneven shoulders, thoracic kyphosis, scoliosis, O-shaped legs, and toe valgus increased, while that of knee hyperextension, flat feet and pes valgus decreased (P

وصف الملف: electronic resource

العلاقة: https://www.chinagp.net/fileup/1007-9572/PDF/zx20220251.pdfTest; https://doaj.org/toc/1007-9572Test

الوصول الحر: https://doaj.org/article/5d192a666a3e4ea99599efbcaf3e7978Test

المؤلفون: Li, Fengling, Shi, Qi, Xiong, Tao, Li, Yang, Zheng, Yuxi, Jiang, Guolu, Duan, Diana S., Wei, Xuemei, Cui, Lijun, Chen, Zhaoxia

المصدر: Maternal & Child Nutrition ; volume 20, issue 1 ; ISSN 1740-8695 1740-8709

الوصف: Limited studies have been conducted on Chinese women's willingness to donate milk following perinatal loss. In this study, we explore the relationship among childbirth trauma, willingness to donate milk, and resilience in women following perinatal loss, and the mediating effect of resilience between childbirth trauma and willingness to donate milk. A cross‐sectional study was carried out throughout 4 months. We used convenience sampling methods and recruited 241 women following a perinatal loss from eight tertiary hospitals in Sichuan Province, China. Participants completed four questionnaires during a face‐to‐face individual interview: the general information questionnaire, the Willingness to Donate Milk Scale (WMDS), the City Birth Trauma Scale, and the Brief Resilience Scale. SPSS 20.0 was used to analyze the collected data. In our study, childbirth trauma was negatively correlated with the total and each dimension score of WMDS ( p < 0.001). Resilience was positively correlated with the total and each dimension score of WMDS ( p < 0.001). Resilience partially mediated the relationship between childbirth‐related symptoms and willingness to donate milk ( β = −0.38, 95% confidence interval [CI]: −0.50 to −0.26), which accounted for 69.03% of the total effect. Resilience partially mediated the relationship between general symptoms and willingness to donate milk ( β = −0.31, 95% CI: −0.40 to −0.21), which accounted for 66.89% of the total effect. Resilience partially mediated the relationship between childbirth trauma and willingness to donate milk in women following perinatal loss. Our findings suggest that resilience can play a significant role in mediating the relationship between childbirth trauma and willingness to donate milk in women following perinatal loss. These results could help healthcare professionals design interventions for physical and mental recovery after perinatal loss.

الإتاحة: https://doi.org/10.1111/mcn.13557Test

المؤلفون: Fang, Jianxia, Zheng, Yuxi, Mou, Haochen, Shi, Meipan, Yu, Wangshu, Du, Chixin

المصدر: Frontiers in Pediatrics ; volume 10 ; ISSN 2296-2360

مصطلحات موضوعية: Pediatrics, Perinatology and Child Health

الوصف: Purpose Myopia treatment using orthokeratology (ortho-k) slows myopia progression. However, it is not equally effective in all patients. We aimed to predict the treatment effect of ortho-k using a machine-learning-assisted (ML) prediction model. Methods Of the 119 patients who started ortho-k treatment between January 1, 2019, and January 1, 2022, 91 met the inclusion criteria and were included in the model. Ocular parameters and clinical characteristics were collected. A logistic regression model with least absolute shrinkage and selection operator regression was used to select factors associated with the treatment effect. Results Age, baseline axial length, pupil diameter, lens wearing time, time spent outdoors, time spent on near work, white-to-white distance, anterior corneal flat keratometry, and posterior corneal astigmatism were selected in the model (aera under curve: 0.949). The decision curve analysis showed beneficial effects. The C-statistic of the predictive model was 0.821 (95% CI: 0.815, 0.827). Conclusion Ocular parameters and clinical characteristics were used to predict the treatment effect of ortho-k. This ML-assisted model may assist ophthalmologists in making clinical decisions for patients, improving myopia control, and predicting the clinical effect of ortho-k treatment via a retrospective non-intervention trial.

الإتاحة: https://doi.org/10.3389/fped.2022.1057863Test

المؤلفون: Zheng, Yuxi, Valikodath, Nita, Woodward, Richmond, Allen, Ariana, Grewal, Dilraj S., Fekrat, Sharon

المصدر: Retina ; ISSN 0275-004X

الوصف: Purpose: To evaluate outcomes of patients who underwent rhegmatogenous retinal detachment (RRD) repair and were started on oral curcumin for proliferative vitreoretinopathy (PVR) prevention. Methods: Retrospective, observational case series of eyes of patients undergoing high-risk RRD repair that were started on curcumin postoperatively. Recommended dosing was 500 mg twice daily for 30 days followed by 500 mg daily for 60 days. The primary outcome was recurrent PVR-related RRD within 6 months and single-surgery retinal reattachment rate (SSRRR). Secondary outcomes included epiretinal membrane (ERM) formation, visual acuity, and curcumin safety profile. Results: 32 eyes of 31 patients met study inclusion criteria. Postoperatively, 2 eyes developed a PVR-related detachment (6.3%), and 2 eyes redetached due to new breaks without PVR (6.3%). Overall, SSRRR was 87.5%. SSRRR without silicone oil was 92.6% (25/27). Of the 12 cases with Grade C PVR-related RD, the SSRRR was 91.7%. Postoperatively, 7 eyes developed an ERM (21.9%), of which 3 underwent ERM removal (9.4%). No patient had gastrointestinal upset or anemia. Conclusions: This proof-of-concept clinical study suggests that oral curcumin is well tolerated and warrants further investigation for its potential to reduce the risk of PVR after RRD repair in eyes at higher risk of PVR.

الإتاحة: https://doi.org/10.1097/iae.0000000000004182Test

المؤلفون: Chen, Liangqiang, Qin, Xing, Wang, Guozheng, Teng, Mengjing, Zheng, Yuxi, Yang, Fan, Du, Hai, Wang, Li, Xu, Yan

المصدر: Bioresour Technol ; ISSN:1873-2976 ; Volume:403

مصطلحات موضوعية: Baijiu fermentation, Microbial community succession, Oxygen, Spatiotemporal heterogeneity, Spontaneous solid-state stacking process

الوصف: The spontaneous solid-state stacking process (SSSP) of Baijiu is an environmentally friendly and cost-effective process for enriching and assembling environmental microorganisms to guarantee the subsequent fermentation efficiency. In this study, how SSSP create spatial heterogeneity of stacking piles were found through spatiotemporal sampling. The degree of difficulty in oxygen exchange categorizes the stacking pile into depleted (≤4%), transitional (4 %-17 %), and enriched (≥17 %) oxygen-defined layers. This results in variation in succession rates (Vdepleted > Vtransitional > Venriched), which accelerates spatial heterogeneity during SSSP. As a dominant species (65 %-99 %) in depleted and transitional layers, Acetilactobacillus jinshanensis can rapidly reduce oxygen disturbance by upregulating poxL and catE, that sustains spatial heterogeneity. The findings demonstrated the value of oxygen control in shaping spatial heterogeneity during SSSP processes, which can create specific functional microbiome. Adding spatial heterogeneity management will help achieve more precise control of such solid-state fermentation systems.

العلاقة: https://doi.org/10.1016/j.biortech.2024.130854Test; https://pubmed.ncbi.nlm.nih.gov/38761866Test

الإتاحة: https://doi.org/10.1016/j.biortech.2024.130854Test
https://pubmed.ncbi.nlm.nih.gov/38761866Test

المؤلفون: Zheng, Yuxi, Woodward, Richmond, Feng, Henry L., Lee, Terry, Zhang, Xinxin, Pant, Praruj, Thomas, Akshay S., Fekrat, Sharon

المصدر: Retina ; volume 44, issue 1, page 159-165 ; ISSN 0275-004X

الوصف: Background/Purpose: To evaluate the status of the posterior vitreous hyaloid on presenting optical coherence tomography images of the macula and its relationship to clinical characteristics, treatment patterns, and outcomes in eyes with central retinal vein occlusion. Methods: This is a retrospective longitudinal cohort study of consecutive patients with acute, treatment-naive central retinal vein occlusion diagnosed between 2009 and 2021 who had at least 12 months of follow-up. Clinical characteristics, treatment patterns, and outcomes were analyzed between eyes stratified based on the presence or absence of a complete posterior vitreous detachment (PVD) on optical coherence tomography at presentation. Results: Of 102 acute, treatment-naive central retinal vein occlusions identified, 52 (51%) had complete PVD at presentation and 50 (49%) did not. Central subfield thickness was significantly lower in those with complete PVD (12 months: 284.9 ± 122.9 µ m vs. 426.8 ± 286.4 µ m, P < 0.001; last follow-up: 278 ± 127.9 vs. 372.8 ± 191.0 µ m, P = 0.022). One-year intravitreal injection burden was significantly less for those with a complete PVD than those without (5.1 ± 3.6 injections vs. 6.7 ± 3.3 injections, P = 0.013). Conclusion: Central retinal vein occlusion with complete PVD on presentation had significantly lower central subfield thickness and 1-year injection burden. Assessment of the vitreomacular interface in central retinal vein occlusion may serve as a prognostic imaging biomarker.

الإتاحة: https://doi.org/10.1097/iae.0000000000003932Test

المؤلفون: Zheng, Yuxi, Wang, Yingwei, Jiang, Yi, Wang, Junwen, Li, Shiqiang, Xiao, Xueshan, Sun, Wenmin, Wang, Panfeng, Zhang, Qingjiong, Jia, Xiaoyun

المساهمون: National Natural Science Foundation of China, the Science and Technology Planning Projects of Guangzhou

المصدر: British Journal of Ophthalmology ; page bjo-2023-323557 ; ISSN 0007-1161 1468-2079

مصطلحات موضوعية: Cellular and Molecular Neuroscience, Sensory Systems, Ophthalmology

الوصف: Aims To investigate the clinical characteristics of Leber hereditary optic neuropathy (LHON) with mtDNA primary mutations to better understand features associated with prognosis. Methods This study enrolled 1540 LHON patients from 1516 unrelated families genetically confirmed by Sanger or whole-mitochondrial sequencing between 1997 and 2022. The spectrum of variants was summarised and compared in different ethnic groups. Clinical data from outpatients were collected, including onset age, disease course, optic disc categories and the corresponding visual acuity. Results Of the 1516 LHON families, 13 pathogenic mtDNA variants were detected, in which the proportion of m.11778G>A, m.3460G>A and m.3635G>A was significantly different from non-East Asians (p<0.0001). About 95% (1075/1131) of patients were between 8 and 40 years old at onset, with a median onset age of 16. The eyes of m.14484T>C patients presented with better visual acuity and slower progression across patients with different onset ages and initial severity. Eyes (N=439) with available fundus images were divided into four categories (C1–C4). The progression grades were derived from the category and the corresponding time course, where a higher grade (C3–C4 within 1 year) was associated with greater visual impairment than a lower grade (C1–C2 over 1 year) (p=4.60E-05) . A prognostic matrix showed that later onset and a higher progression grade are associated with higher risk of blindness. Conclusion Compared with non-East Asians, Chinese LHON patients had higher proportions of m.11778G>A and m.3635G>A and lower m.3460G>A mutations. A novel progression grade derived from optic disc category was proposed. The prognostic matrix indicated that lower grade and younger-onset age are the most favourable prognostic factors.

الإتاحة: https://doi.org/10.1136/bjo-2023-323557Test