المؤلفون: CAO Feng-hua, XIE Song-yu, LI Xiao-min, WU Wen-ya, WU Xiao-ping, ZHANG Jun-li, FU Jun-sheng

المصدر: Liang you shipin ke-ji, Vol 30, Iss 5, Pp 197-204 (2022)

مصطلحات موضوعية: cordyceps militaris, noodles, alleviate physical fatigue, exhaustive swimming, blood lipid concentration, Food processing and manufacture, TP368-456, Nutrition. Foods and food supply, TX341-641

الوصف: This research studied the effect of cordyceps militaris noodles on alleviating physical fatigue and concentration of serum lipids in mouse. The mouse were divided into feed group, blank noodle group, low dose of C.militaris noodles group and high dose of C.militaris noodles group, and the animal model of swimming fatigue was established. The exhausted swimming time of mouse in each group was recorded, and the related indexes of alleviating physical fatigue and affecting lipid concentration in mouse were measured. The results show that there was no significant difference in body weight of mouse in each group. Compared with feed group and blank noodle group, cordyceps militaris noodles could effectively prolong the exhausted swimming time of mouse (P

وصف الملف: electronic resource

العلاقة: http://lyspkj.ijournal.cn/lyspkj/article/abstract/20220523?st=article_issueTest; https://doaj.org/toc/1007-7561Test

الوصول الحر: https://doaj.org/article/d53da5cf52894c248e0c2c500b083abdTest

المؤلفون: Zhang, Hai-Ming, Luo, Dan, Chen, Rui, Wang, Shu-Han, Zhao, Ya-Juan, Li, Jin-Xiao, Zhou, Min-Feng, Yu, Zhao-Min, Zhang, Jun-Li, Liang, Feng-Xia

المصدر: Frontiers in Neuroscience ; volume 17 ; ISSN 1662-453X

الوصف: Central nervous system (CNS) disorders exhibit complex neurophysiological and pathological mechanisms, which seriously affect the quality of life in patients. Acupuncture, widely accepted as complementary and alternative medicine, has been proven to exert significant therapeutic effects on CNS diseases. As a part of the innate immune system, NLRP3 inflammasome contributes to the pathogenesis of CNS diseases via regulating neuroinflammation. To further explore the mechanisms of acupuncture regulating NLRP3 inflammasome in CNS diseases, our study focused on the effects of acupuncture on neuroinflammation and the NLRP3 inflammasome in vascular dementia, Alzheimer’s disease, stroke, depression, and spinal cord injury. This study confirmed that the activation of NLRP3 inflammasome promotes the development of CNS diseases, and inhibiting the activation of NLRP3 inflammasome is a potential key target for the treatment of CNS diseases. In addition, it is concluded that acupuncture alleviates neuroinflammation by inhibiting the activation of the NLRP3 inflammasome pathway, thereby improving the progression of CNS diseases, which provides a theoretical basis for acupuncture to attenuate neuroinflammation and improve CNS diseases.

الإتاحة: https://doi.org/10.3389/fnins.2023.1118508Test

المؤلفون: Liu, Zhan-Bo, Zhang, Jun-Li, Papp, Viktor, Dai, Yu-Cheng

مصطلحات موضوعية: QH301 Biology / biológia

الوصف: Two new wood-inhabiting fungi Hermanssonia fimbriata sp. nov. and Phlebia austroasiana sp. nov. in the Meruliaceae family are described and illustrated from southwestern China based on molecular and morphological evidence. The characteristics of H. fimbriata include annual, resupinate basidiomata, the absence of cystidia and cystidioles, oblong ellipsoid basidiospores of 5–6 × 2.4–3 μm, and growth on rotten gymnosperm wood in the east Himalayas. Its basidiomata change drastically upon drying, from being a light-coloured, juicy, papillose-to-wrinkled hymenophore, to a dark-coloured, corky-to-gelatinous, and more or less smooth hymenophore. The characteristics of Ph. austroasiana include annual, resupinate basidiomata, a hydnoid hymenophore, 2–3 spines per mm, the presence of tubular cystidia of 20–25 × 3–3.5 µm, oblong ellipsoid basidiospores of 4.4–5.2 × 2.1–3 μm, and growth on angiosperm wood in tropical forests in the southern Yunnan Province. The phylogenetic analyses based on the combined 2-locus dataset (ITS1-5.8S-ITS2 (ITS) + nuclear large subunit RNA (nLSU)) confirm the placement of two new species, respectively, in Hermanssonia and Phlebia s. lato. Phylogenetically, the closely-related species to these two new species are discussed.

وصف الملف: text

العلاقة: http://real.mtak.hu/150650/1/Liu_etal_2022_Journal_of_Fungi.pdfTest; Liu, Zhan-Bo and Zhang, Jun-Li and Papp, Viktor and Dai, Yu-Cheng (2022) Taxonomy and Phylogeny of Meruliaceae with Descriptions of Two New Species from China. JOURNAL OF FUNGI, 8 (5). No.-501. ISSN 2309-608X

الإتاحة: https://doi.org/10.3390/jof8050501Test
http://real.mtak.hu/150650Test/
http://real.mtak.hu/150650/1/Liu_etal_2022_Journal_of_Fungi.pdfTest

المؤلفون: CAO Feng-hua, ZENG Bao-jia, HU Xin, QIU Shao-feng, WU Xiao-ping, ZHANG Jun-li, FU Jun-sheng

المصدر: Feed Research; 2023, Vol. 46 Issue 21, p58-63, 6p

مصطلحات موضوعية: MICE, LACTATE dehydrogenase, WHEAT bran, BRAN

مستخلص: The experiment was to study the effects of Tremella fuciformis by-product on the growth status, liver function, immune function and endurance of mice. Three kinds of Tremella fuciformis by-product were taken and low-mediumhigh dose groups were set respectively. The growth status indexes of mice in each group were recorded, and the immune functional indexes and liver functional indexes were determined. The animal fatigue model was established by swimming experiment to explore the effects of feed on the endurance of mice. The results showed that the low-dose fungus bran group and low-dose fungus bran group could not damage the liver tissue of mice and promote the growth and development of mice. The average daily gain of mice in low-dose fungus bran group, medium-dose fungus bran group and low-dose fungus bran material group was 14.52%, 11.29% and 14.52% higher than that in control group. The activity of lactate dehydrogenase was extremely increased (P<0.01) and the content of serum urea nitrogen was extremely decreased (P<0.01), and the endurance of mice was increased. The experiment indicates taht using the bran or pedicle of Tremella fuciformis as feed excipients can promote mouse growth performance, improve immunity ability and endurance without affecting liver function. [ABSTRACT FROM AUTHOR]

: Copyright of Feed Research is the property of Editorial Board of Feed Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Wang, Di, Zhang, Jun Li, Wang, Yun, Zambonelli, Alessandra, Hall, Ian, Xiong, Wei-Ping

المصدر: Italian Journal of Mycology; V. 50 (2021); 63-77 ; Italian Journal of Mycology; Vol. 50 (2021); 63-77 ; 2531-7342

مصطلحات موضوعية: saffron milk cap, cultivation, New Zealand, China, productivity

الوصف: From the early 1800s science virtually ignored the cultivation of edible mycorrhizal mushrooms other than the true truffles. The drought was finally broken by Nicole Poitou when she cultivated Lactarius deliciosus and Suillus granulatus in the Institut National de la Recherche Agronomique’s laboratories at Pont-de-la-Maye, France, in the mid-1970s. However, another 20 years were to pass before Yun Wang working at Invermay Agricultural Centre near Dunedin, New Zealand, was able to begin the routine cultivation of L. deliciosus. The purpose of this paper is to document the history of the cultivation of L. deliciosus in New Zealand since its introduction in the late 1990s, its spread back to Europe and its subsequent introduction into Yunnan, Tibet and Sichuan starting about 2014.

وصف الملف: application/pdf

العلاقة: https://italianmycology.unibo.it/article/view/12908/12803Test; https://italianmycology.unibo.it/article/view/12908/12804Test; https://italianmycology.unibo.it/article/view/12908Test

الإتاحة: https://doi.org/10.6092/issn.2531-7342/12908Test
https://italianmycology.unibo.it/article/view/12908Test

المؤلفون: Gong, Xun, Liu, Wei-Xiang, Tang, Xiao-Po, Wang, Jian, Liu, Jian, Huang, Qing-Chun, Liu, Wei, Fang, Yong-Fei, He, Dong-Yi, Liu, Ying, Gao, Ming-Li, Wu, Qing-Jun, Chen, Shi, Li, Zhen-Bin, Wang, Yue, Xie, Yan-Ming, Zhang, Jun-Li, Zhou, Cai-Yun, Ma, Li, Wang, Xin-Chang, Zhang, Chi, Jiang, Quan

المصدر: Frontiers in Pharmacology ; volume 12 ; ISSN 1663-9812

الوصف: Traditional Chinese medicine (TCM) has been used successfully to treat rheumatoid arthritis (RA). Qingre Huoxue treatment (Qingre Huoxue decoction (QRHXD)/Qingre Huoxue external preparation (QRHXEP)) is a therapeutic scheme of TCM for RA. To date, there have been few studies comparing the efficacy and safety of QRHXD and conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) for the treatment of active RA. This was investigated in a multicenter, double-blind, randomized controlled trial involving 468 Chinese patients with active RA [disease activity score (DAS)-28 > 3.2] treated with QRHXD/QRHXEP (TCM group), methotrexate plus hydroxychloroquine [Western medicine (WM) group], or both [integrative medicine (IM) group]. Patients were followed up for 24 weeks. The primary outcome measure was the change in DAS-28 from baseline to 24 weeks. The secondary outcome measures were treatment response rate according to American College of Rheumatology 20, 50, and 70% improvement criteria (ACR-20/50/70) and the rate of treatment-related adverse events (TRAEs). The trial was registered at ClinicalTrials.gov (NCT02551575). DAS-28 decreased in all three groups after treatment ( p < 0.0001); the score was lowest in the TCM group ( p < 0.05), while no difference was observed between the WM and IM groups ( p > 0.05). At week 24, ACR-20 response was 73.04% with TCM, 80.17% with WM, and 73.95% with IM (based on the full analysis set [FAS], p > 0.05); ACR-50 responses were 40.87, 47.93, and 51.26%, respectively, (FAS, p > 0.05); and ACR-70 responses were 20.87, 22.31, and 25.21%, respectively, (FAS, p > 0.05). Thus, treatment efficacy was similar across groups based on ACR criteria. On the other hand, the rate of TRAEs was significantly lower in the TCM group compared to the other groups ( p < 0.05). Thus, QRHXD/QRHXEP was effective in alleviating the symptoms of active RA—albeit to a lesser degree than csDMARDs—with fewer side effects. Importantly, combination ...

الإتاحة: https://doi.org/10.3389/fphar.2021.679588Test

المؤلفون: Gao, Wei, Xu, Fu‐Chun, Long, Lu, Li, Yang, Zhang, Jun‐Li, Chong, Leelyn, Botella, Jose Ramon, Song, Chun‐Peng

المساهمون: National Natural Science Foundation of China

المصدر: Plant Biotechnology Journal ; volume 18, issue 7, page 1573-1584 ; ISSN 1467-7644 1467-7652

الوصف: Summary Pigment glands, also known as black glands or gossypol glands, are specific for Gossypium spp. These glands strictly confine large amounts of secondary metabolites to the lysigenous cavity, leading to the glands’ intense colour and providing defence against pests and pathogens. This study performed a comparative transcriptome analysis of glanded versus glandless cotton cultivars. Twenty‐two transcription factors showed expression patterns associated with pigment glands and were characterized. Phenotypic screening of the genes, via virus‐induced gene silencing, showed an apparent disappearance of pigmented glands after the silencing of a pair of homologous MYB‐encoding genes in the A and D genomes (designated as CGP1 ). Further study showed that CGP1a encodes an active transcription factor, which is specifically expressed in the gland structure, while CGP1d encodes a non‐functional protein due to a fragment deletion, which causes premature termination. RNAi‐mediated silencing and CRISPR knockout of CGP1 in glanded cotton cultivars generated a glandless‐like phenotype, similar to the dominant glandless mutant Gl 2 e . Microscopic analysis showed that CGP1 knockout did not affect gland structure or density, but affected gland pigmentation. The levels of gossypol and related terpenoids were significantly decreased in cgp1 mutants, and a number of gossypol biosynthetic genes were strongly down‐regulated. CGP1 is located in the nucleus where it interacts with GoPGF, a critical transcription factor for gland development and gossypol synthesis. Our data suggest that CGP1 and GoPGF form heterodimers to control the synthesis of gossypol and other secondary metabolites in cotton.

الإتاحة: https://doi.org/10.1111/pbi.13323Test

المؤلفون: Liu, Ding-qian, Zhang, Jun-li, Pan, Zhi-fen, Mai, Jun-tao, Mei, Heng-jun, Dai, Yue, Zhang, Lu, Wang, Qing-zhong

المساهمون: National Key R&D Program of China, International cooperation and exchange program of Shanghai Municipal, Shanghai Municipal health commission, Jiaxing Municipal science & technology project, Open Fund of Shanghai Key Laboratory of Tuberculosis

المصدر: International Journal of Medical Microbiology ; volume 310, issue 1, page 151378 ; ISSN 1438-4221

مصطلحات موضوعية: Infectious Diseases, Microbiology (medical), General Medicine, Microbiology

الإتاحة: https://doi.org/10.1016/j.ijmm.2019.151378Test
https://api.elsevier.com/content/article/PII:S1438422119301092?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1438422119301092?httpAccept=text/plainTest

المؤلفون: Lu, Wei, Yang, Chao, Du, Peng, Zhang, Jun-Li, Zhang, Jia-Cheng

المصدر: Artificial Cells, Nanomedicine, and Biotechnology ; volume 47, issue 1, page 1466-1470 ; ISSN 2169-1401 2169-141X

الإتاحة: https://doi.org/10.1080/21691401.2019.1601102Test

المؤلفون: Tian, Huai Zhen, Han, Li Xia, Zhang, Jun Li, Li, Xing Lin, Kawahara, Takayuki, Yukawa, Tomohisa, López-Pujol, Jordi, Kumar, Pankaj, Chung, Myong Gi, Chung, Mi Yoon

المصدر: Scientific Reports ; volume 8, issue 1 ; ISSN 2045-2322

مصطلحات موضوعية: Multidisciplinary

الوصف: Little is known about levels and patterns of genetic diversity for the entire range of endangered orchids native to China, Korea, and Japan. In this study, we focus on Cypripedium japonicum and suggest three hypotheses: 1) that genetic drift has been a primary evolutionary force; 2) that populations in central and western China harbor higher levels of genetic variation relative to those from eastern China; and 3) that C . japonicum in China maintains the highest genetic variation among the three countries. Using ISSR and SCoT markers, we investigated genetic diversity in 17 populations to test the three hypotheses. As anticipated, we found low levels of genetic diversity at the species level with substantially high degree of genetic divergence, which can be mainly attributed to random genetic drift. Chinese populations harbor the highest within-population genetic variation, which tends to increase from east to west. We also found a close relationship between Korean populations and central/western Chinese populations. Historical rarity coupled with limited gene flow seems to be important factors for shaping genetic diversity and structure of C . japonicum . Our results indicate that the mountain areas in central and western China were likely refugia at the Last Glacial Maximum.

الإتاحة: https://doi.org/10.1038/s41598-018-24912-zTest
https://www.nature.com/articles/s41598-018-24912-z.pdfTest
https://www.nature.com/articles/s41598-018-24912-zTest