المؤلفون: Benali, Faysal, Stolze, Lotte J, Rozeman, Anouk D, Dinkelaar, Wouter, Coutinho, Jonathan M, Emmer, Bart J, Gons, Rob A R, Yo, Lonneke F S, van Tuijl, Julia H, Boukrab, Issam, van Dam-Nolen, Dianne H K, van den Wijngaard, Ido R, Lycklama À Nijeholt, Geert J, de Laat, Karlijn F, van Dijk, Lukas C, den Hertog, Heleen M, Flach, H Zwenneke, Wermer, Marieke J H, van Walderveen, Marianne A A, Brouwers, Paul J A M, Bulut, Tomas, Vermeer, Sarah E, Bernsen, Marie Louise E, Uyttenboogaart, Maarten, Bokkers, Reinoud P H, Boogaarts, Jeroen D, de Leeuw, Frank-Erik, van der Worp, H Bart, van der Schaaf, Irene C, Schonewille, Wouter J, Vos, Jan A, Remmers, Michel J M, Imani, Farshad, Dippel, Diederik W J, van Zwam, Wim H, Nederkoorn, Paul J, van Oostenbrugge, Robert J

المساهمون: MS Radiologie, Neurologen, Brain, Circulatory Health

مصطلحات موضوعية: COVID-19, Communicable Disease Control, Endovascular Procedures, Humans, Netherlands/epidemiology, Pandemics, SARS-CoV-2, Stroke/drug therapy, Thrombectomy, Thrombolytic Therapy, Time-to-Treatment, Treatment Outcome, NIHSS, Acute stroke care, Endovascular thrombectomy, Lockdown, Intravenous thrombolytics, Clinical Neurology, Journal Article

الوصف: Introduction: We investigated the impact of the Corona Virus Disease 2019 (COVID-19) pandemic and the resulting lockdown on reperfusion treatments and door-to-treatment times during the first surge in Dutch comprehensive stroke centers. Furthermore, we studied the association between COVID-19-status and treatment times. Methods: We included all patients receiving reperfusion treatment in 17 Dutch stroke centers from May 11th, 2017, until May 11th, 2020. We collected baseline characteristics, National Institutes of Health Stroke Scale (NIHSS) at admission, onset-to-door time (ODT), door-to-needle time (DNT), door-to-groin time (DGT) and COVID-19-status at admission. Parameters during the lockdown (March 15th, 2020 until May 11th, 2020) were compared with those in the same period in 2019, and between groups stratified by COVID-19-status. We used nationwide data and extrapolated our findings to the increasing trend of EVT numbers since May 2017. Results: A decline of 14% was seen in reperfusion treatments during lockdown, with a decline in both IVT and EVT delivery. DGT increased by 12 min (50 to 62 min, p-value of < 0.001). Furthermore, median NIHSS-scores were higher in COVID-19 - suspected or positive patients (7 to 11, p-value of 0.004), door-to-treatment times did not differ significantly when stratified for COVID-19-status. Conclusions: During the first surge of the COVID-19 pandemic, a decline in acute reperfusion treatments and a delay in DGT was seen, which indicates a target for attention. It also appeared that COVID-19-positive or -suspected patients had more severe neurologic symptoms, whereas their EVT-workflow was not affected.

وصف الملف: application/pdf

العلاقة: https://dspace.library.uu.nl/handle/1874/447622Test

الإتاحة: https://dspace.library.uu.nl/handle/1874/447622Test

المؤلفون: Benali, Faysal, Stolze, Lotte J., Rozeman, Anouk D., Dinkelaar, Wouter, Coutinho, Jonathan M., Emmer, Bart J., Gons, Rob A. R., Yo, Lonneke F. S., van Tuijl, Julia H., Boukrab, Issam, van Dam-Nolen, Dianne H. K., van den Wijngaard, Ido R., Lycklama �� Nijeholt, Geert J., de Laat, Karlijn F., van Dijk, Lukas C., den Hertog, Heleen M., Flach, H. Zwenneke, Wermer, Marieke J. H., van Walderveen, Marianne A. A., Brouwers, Paul J. A. M., Bulut, Tomas, Vermeer, Sarah E., Bernsen, Marie Louise E., Uyttenboogaart, Maarten, Bokkers, Reinoud P. H., Boogaarts, Jeroen D., de Leeuw, Frank-Erik, van der Worp, H. Bart, van der Schaaf, Irene C., Schonewille, Wouter J., Vos, Jan A., Remmers, Michel J. M., Imani, Farshad, Dippel, Diederik W. J., van Zwam, Wim H., Nederkoorn, Paul J., van Oostenbrugge, Robert J.

الوصف: Additional file 1: Supplemental table 1. Subdivision in regions. *Total number of new COVID-19 hospital admissions in all hospital in a region from March 15th, 2020 until May 11th, 2020, based on data from the Dutch public health service (GGD)16 and Statistics Netherlands (CBS)17. This illustrates the severity of crowding due to COVID-19 in a region. Supplemental figure 1. Map of the different regions with corresponding EVT-centers. *Total number of new COVID-19 hospital admissions in all hospital in a region from March 15th, 2020 until May 11th, 2020, based on data from the Dutch public health service (GGD) [16] and Statistics Netherlands (CBS) [17]. This illustrates the severity of crowding due to COVID-19 in a region. Supplemental table 2. All treated AIS-patients from March 15th until May 11th, 2020 (lockdown) and 2019 (reference), subdivided in regions. * All times are displayed in minutes.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224cc51ba03ec15540fcb5cf31c9e050Test