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1دورية أكاديمية
المؤلفون: Xinhua Li, Xuejun Wang, Zhouyang Hu, Zhaoxiong Chen, Haoxi Li, Xiaoming Liu, Zhi Yao Yong, Shanjing Wang, Zhanying Wei, Yingchao Han, Jun Tan, Cong Li, Xiao bo He, Guixin Sun, Desheng Wu, Lijun Li
المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
الوصف: Abstract Epidemiological studies have concluded that hyperlipidemia and atherosclerosis were related to intervertebral disc degeneration (IVDD). The presence of oxidized low density lipoprotein (ox-LDL) and the expression of lectin-like oxidized low density lipoprotein receptor 1 (LOX-1) have not been explored in this tissue. In this study, we investigated the presence of ox-LDL and the expression of its receptor LOX-1 in non-degenerated, degenerated or herniated human intervertebral discs (IVDs). The expression of LOX-1 and matrix metalloproteinase 3 (MMP3) were studied after incubating nucleus pulposus cells (NPCs) with ox-LDL. The presence of ox-LDL and LOX-1 was positively related with the extent of IVDD in nucleus pulposus (NP), end-plate cartilage and outer annulus fibrous, but not with the extent of degeneration of inter annulus fibrous. Ox-LDL significantly reduced the viability of human NPCs in a dose and time-dependent manner, and increased the expression of MMP3 induced by LOX-1. Pretreatment with anti-human LOX-1 monoclonal antibody reversed these effects. Ox-LDL, principally mediated by LOX-1, enhanced MMP3 production in NPCs through the NF-κB signaling pathway. In conclusion, increased accumulation of ox-LDL and LOX-1 in IVDs indicates a specific role of the receptor-ligand interaction in degeneration or herniation of IVDs.
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2045-2322Test
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2
المؤلفون: Guan-ya Han, Xiao-li Wu, Dong-mei Li, Hai-rui Cai, Jun-jun Zhou, Xiao-bo He
المصدر: Chinese Journal of Integrative Medicine. 29:483-489
مصطلحات موضوعية: Complementary and alternative medicine, Pharmacology (medical), General Medicine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::e8b28f5f7c17ddba5294b3c0d4ac84dcTest
https://doi.org/10.1007/s11655-023-3730-0Test -
3دورية أكاديمية
المؤلفون: Guo-dong Cao, Xiao-bo He, Qiang Sun, Sihan Chen, Ke Wan, Xin Xu, Xudong Feng, Peng-ping Li, Bo Chen, Mao-ming Xiong
المصدر: Frontiers in Oncology, Vol 10 (2020)
مصطلحات موضوعية: cancer, oncolytic virus, application, review, diagnosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
الوصف: Cancer has always been an enormous threat to human health and survival. Surgery, radiotherapy, and chemotherapy could improve the survival of cancer patients, but most patients with advanced cancer usually have a poor survival or could not afford the high cost of chemotherapy. The emergence of oncolytic viruses provided a new strategy for us to alleviate or even cure malignant tumors. An oncolytic virus can be described as a genetically engineered or naturally existing virus that can selectively replicate in cancer cells and then kill them without damaging the healthy cells. There have been many kinds of oncolytic viruses, such as herpes simplex virus, adenovirus, and Coxsackievirus. Moreover, they have different clinical applications in cancer treatment. This review focused on the clinical application of oncolytic virus and predicted the prospect by analyzing the advantages and disadvantages of oncolytic virotherapy.
وصف الملف: electronic resource
العلاقة: https://www.frontiersin.org/article/10.3389/fonc.2020.01786/fullTest; https://doaj.org/toc/2234-943XTest
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4
المؤلفون: Feng Li, Zhen-yu Yang, Jun-jun Shi, Xiao-bo He
المصدر: Optics express. 30(21)
مصطلحات موضوعية: Atomic and Molecular Physics, and Optics
الوصف: Plasmonic demultiplexers hold promise for the realization of the subwavelength and high-splitting ratio dichroic splitter and have a wide range of applications from optical communication, and manipulation to ultrafast data treatment. However, this vision has not been realized for a long time due to lacking the suitable splitting structure design, which limits its further development of integrated photonic circuits. Here, we demonstrate a plasmonic demultiplexer with subwavelength feature size (0.54 µm) and broadband spectral (620-870 nm) range, and high-splitting ratio (17 dB in experiments and 20 dB in calculations). It consists of two adjacent Fabry–Perot cavities (covered by PMMA polymer) and coupling gratings, which are integrated with the Au waveguide. The relatively simple double cavities design of our device has a simple theoretical analysis and fabrication process. Our work has relevance for various optical applications, such as multiple wavelength photodetectors and optical multichannel interconnects.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ae9e70cd01dfcd3b37de357d15147dTest
https://pubmed.ncbi.nlm.nih.gov/36258357Test -
5دورية أكاديمية
المؤلفون: Qiao Shi, Kang-Shu Liao, Kai-Liang Zhao, Wei-Xing Wang, Teng Zuo, Wen-Hong Deng, Chen Chen, Jia Yu, Wen-Yi Guo, Xiao-Bo He, Ablikim Abliz, Peng Wang, Liang Zhao
المصدر: Mediators of Inflammation, Vol 2015 (2015)
الوصف: Hydrogen (H2), a new antioxidant, was reported to reduce •OH and ONOO− selectively and inhibit certain proinflammatory mediators to product, without disturbing metabolic redox reactions or ROS involved in cell signaling. We herein aim to explore its protective effects on acute renal injury in sodium taurocholate-induced acute pancreatitis and its possible mechanisms. Rats were injected with hydrogen-rich saline (HRS group) or normal saline (SO and SAP group) through tail intravenously (6 mL/kg) and compensated subcutaneously (20 mL/kg) after successful modeling. Results showed that hydrogen-rich saline attenuated the following: (1) serum Cr and BUN, (2) pancreatic and renal pathological injuries, (3) renal MDA, (4) renal MPO, (5) serum IL-1β, IL-6, and renal TNF-α, HMGB1, and (6) tyrosine nitration, IκB degradation, and NF-κB activation in renal tissues. In addition, it increased the level of IL-10 and SOD activity in renal tissues. These results proved that hydrogen-rich saline attenuates acute renal injury in sodium taurocholate-induced acute pancreatitis, presumably because of its detoxification activity against excessive ROS, and inhibits the activation of NF-κB by affecting IκB nitration and degradation. Our findings highlight the potential value of hydrogen-rich saline as a new therapeutic method on acute renal injury in severe acute pancreatitis clinically.
وصف الملف: electronic resource
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6دورية أكاديمية
المؤلفون: Shun, Wu, Xiao-bo, He, Li-jun, Wang, Kuo-Chih, Chou
المصدر: International Journal of Minerals, Metallurgy and Materials
مصطلحات موضوعية: rutile titania, hydrolysis, spherical particles, adsorption
الوصف: Rutile titania (TiO2) was successfully prepared via hydrolysis of TiCl4 in the presence of AlCl3. The powders were characterized by X-ray powder diffraction (XRD), scanning electron microscopy (SEM), and Brunauer−Emmett−Teller (BET) surface area analysis. In the present system, AlCl3 functions as a nucleating agent and induces the formation of rutile TiO2. The influences of HCl and isopropanol concentrations on the purity and morphology of the rutile TiO2 were investigated. The purity of the rutile TiO2 increased with increasing concentration of HCl. Evenly dispersed rutile TiO2 particles with a spherical morphology were obtained when the HCl and isopropanol concentrations were 0.5 and 1 mol·L−l, respectively. Furthermore, the prepared TiO2 powders were used in adsorption tests of the heavy metal pollutant Cr(VI). Rutile TiO2 sample S-9 demonstrated greater adsorption performance and a removal efficiency that was greater than 99.95% after 60 min of adsorption when the Cr(VI) concentration was 200 mg·L−l. The maximum adsorption capacity on rutile TiO2 was 28.9 mg·g−1. This work provides an easy path to prepare a high-performance rutile TiO2 adsorbent with potential applications in water pollution treatment.
العلاقة: https://ustb.researchcommons.org/ijmmm/vol27/iss8/15Test; https://link.springer.com/content/pdf/10.1007/s12613-020-1965-8.pdfTest
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7دورية أكاديمية
المؤلفون: Shi-yuan, Liu, Yu-lan, Zhen, Xiao-bo, He, Li-jun, Wang, Kuo-chih, Chou
المصدر: International Journal of Minerals, Metallurgy and Materials
مصطلحات موضوعية: vanadium slag, molten salt electrolysis, separation, electrochemical analysis
الوصف: Tailings from the vanadium extraction process are discarded each year as waste, which contain approximately 30wt% of Fe. In our previous work, we extracted Fe and Mn from vanadium slag, and Fe and Mn existed in the form of FeCl2 and MnCl2 after chlorination by NH4Cl to achieve effective and green usage of waste containing Fe and Mn. In this work, square wave voltammetry (SWV) and cyclic voltammetry (CV) were applied to investigate the electrochemical behaviors of Fe2+ and Mn2+ in NaCl–KCl melt at 800°C. The reduction processes of Fe2+ and Mn2+ were found to involve one step. The diffusion coefficients of FeCl2 and MnCl2 in molten salt of eutectic mixtures NaCl–KCl molten salt were measured. The electrodeposition of Fe and Mn were performed using two electrodes at a constant cell voltage. The Mn/Fe mass ratio of the electrodeposited product in NaCl–KCl–2.13wt%FeCl2–1.07wt%MnCl2 was 0.0625 at 2.3 V. After the electrolysis of NaCl–KCl–2.13wt%FeCl2–1.07wt%MnCl2 melted at 2.3 V, the electrolysis was again started under 3.0 V and the Mn/Fe mass ratio of the electrodeposited product was 36.4. This process provides a novel method to effectively separate Fe and Mn from simulated chlorinated vanadium slag.
العلاقة: https://ustb.researchcommons.org/ijmmm/vol27/iss12/12Test; https://link.springer.com/content/pdf/10.1007/s12613-020-2140-y.pdfTest
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8
المؤلفون: Shao-Yong, Wang, Qiao-Li, Wang, Jin-Kui, Wu, Xiao-Bo, He, Yong-Jian, Ding, Li-Hui, Wang, Zhao-Fu, Hu
المصدر: Huan jing ke xue= Huanjing kexue. 40(6)
الوصف: Based on the stable isotopes of 73 precipitation samples continuously collected from May to October 2014 and related meteorological statistics in the Dongkemaldi Basin, the characteristics of
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::4f20edb5bdfe2fc1fc4c934a28ea12f1Test
https://pubmed.ncbi.nlm.nih.gov/31854652Test -
9
المؤلفون: Shao-Yong, Wang, Xiao-Bo, He, Jing-Kui, Wu, Yong-Jian, Ding, Zhao-Fu, Hu, Li-Hui, Wang, Gui-Sen, Yang
المصدر: Huan jing ke xue= Huanjing kexue. 40(10)
الوصف: Using 64 precipitation samples collected from June to September 2013 in the Dongkemadi Basin in the source region of the Yangtze River, the pH, conductivity, and main ionic concentration characteristics of precipitation were analyzed. The main ionic sources of precipitation and their relationships with atmospheric circulation were examined using factor analysis, correlation analysis, enrichment factor analysis, and backward trajectory analysis. The results showed that the range of precipitation pH values varied from 5.26 to 9.25 with a weighted average of 6.70, and conductivity ranged from 0.23 to 28.70 μS·cm
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::7941798b867c36c9504a2a9a8d36c4f6Test
https://pubmed.ncbi.nlm.nih.gov/31854810Test -
10
المؤلفون: Shao-Yong, Wang, Xiao-Bo, He, Yong-Jian, Ding, Fu-Xuan, Chang, Jin-Kui, Wu, Zhao-Fu, Hu, Li-Hui, Wang, Gui-Sen, Yang, Ming-Shan, Deng
المصدر: Huan jing ke xue= Huanjing kexue. 41(1)
الوصف: We use 84 rainfall samples collected during June to September 2017 from the Dongkemadi basin, source region of the Yangtze River, China, to analyze the characteristics and influencing factors of stable isotopes in groundwater, and further discuss the groundwater recharge sources. The results showed that the range of groundwater
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::b58b0ba106446ffdc69da0bb4fbc09a1Test
https://pubmed.ncbi.nlm.nih.gov/31854917Test
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