المؤلفون: YANG Danni, ZHAO Mengna, FENG Xiaoye, TONG Jiyu, WANG Hua, CAI Hongbing

المصدر: Zhongliu Fangzhi Yanjiu, Vol 51, Iss 5, Pp 361-367 (2024)

مصطلحات موضوعية: inflammation, ovarian cancer, aged, prognosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

الوصف: Objective To explore the value of blood inflammatory load in predicting overall survival of elderly patients with epithelial ovarian cancer (EOC). Methods Elderly patients with EOC were selected, and their clinical data and peripheral blood parameters were collected. We constructed an inflammation-related blood scoring system using univariate and multivariate Cox regression analysis. The Kaplan-Meier method was used for survival analysis. We used Cox proportional hazards analysis to identify the independent prognostic factors. A nomogram model was constructed based on independent prognostic factors, and the receiver operating characteristic curve, C-index, and calibration curve were used to evaluate the model. Results Patients with high blood inflammatory load had worse prognosis (P=0.002). Compared with the low inflammatory load group, patients with high inflammatory load had later clinical stages and larger ascites volume (P

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1000-8578Test

الوصول الحر: https://doaj.org/article/d09e73b7f3b04bc9b1077403df05cf15Test

المؤلفون: Liang Chun-Bo, Li Wei-Zhong, Xu Lian-Hua, Wang Hua-Bin

المصدر: Zeitschrift für Kristallographie - New Crystal Structures, Vol 239, Iss 3, Pp 401-403 (2024)

مصطلحات موضوعية: 2336246, Physics, QC1-999, Crystallography, QD901-999

الوصف: C13H17NO4, monoclinic, Cc (no. 9), a = 11.6900(4) Å, b = 8.4868(2) Å, c = 14.1607(5) Å, β = 112.549(4)°, V = 1297.49(8) Å3, Z = 4, R gt(F) = 0.0373, wR ref(F 2) = 0.1071, T = 295.5 K.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1433-7266Test; https://doaj.org/toc/2197-4578Test

الوصول الحر: https://doaj.org/article/6e71e583359d4ff29f5c9cd0dd318cbaTest

المؤلفون: Xu Xiaoping, Wang Hua-bin, Cai Shu-qian, Wu Jun-Qi

المصدر: Journal of Laboratory Medicine, Vol 48, Iss 2, Pp 83-90 (2024)

مصطلحات موضوعية: anti-müllerian hormone, systemic lupus erythematosus (sle), antiphospholipid syndrome, antral follicle count, ovarian reserve, Medical technology, R855-855.5

الوصف: To evaluate the ovarian reserve (OR) in women with antiphospholipid syndrome (APS), systemic lupus erythematosus (SLE), especially SLE-associated APS, and to determine the association between OR and clinical and laboratory parameters.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2567-9430Test; https://doaj.org/toc/2567-9449Test

الوصول الحر: https://doaj.org/article/f4111bb751ed45f79b6f047505ac044dTest

المؤلفون: Wang Hua-Bin, Xu Lian-Hua, Shi Ju-Mei, An Jiang-Yong

المصدر: Zeitschrift für Kristallographie - New Crystal Structures, Vol 239, Iss 2, Pp 183-185 (2024)

مصطلحات موضوعية: 2322388, Physics, QC1-999, Crystallography, QD901-999

الوصف: C30H25O7P, monoclinic, P21/c (no. 14), a = 12.1091(3) Å, b = 8.0535(2) Å, c = 25.4435(6) Å, β = 92.169(2)°, V = 2479.49(10) Å3, Z = 4, Rgt(F) = 0.0438, wRref(F2) = 0.1219, T = 150 K.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1433-7266Test; https://doaj.org/toc/2197-4578Test

الوصول الحر: https://doaj.org/article/21006e3375084ce6a43b37ac9751770cTest

المؤلفون: WANG Jin⁃tao, MA Sha, WANG Han, BA Mao⁃wen, CHEN Xian⁃wen, HU Xing⁃yue, LIU Yi⁃ming, CHENG Ou⁃mei, WANG Yu⁃kai, ZHOU Fan, XU Shun⁃liang, SHEN Yue⁃fei, CHEN Wei, DOU Rong⁃hua, LIU Xue⁃dong, HAN Yan⁃qing, WANG Hua⁃long, DING Yan, PAN Xiao⁃ling, HUANG Wei, CHEN Lei, LU Hong, XU Gang, WANG Gang

المصدر: Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 23, Iss 12, Pp 1103-1108 (2023)

مصطلحات موضوعية: conversion disorder, motor disorders, epidemiology, Neurology. Diseases of the nervous system, RC346-429

الوصف: Objective To preliminarily summarize the epidemiological and clinical characteristics of functional movement disorder (FMD) based on movement disorders clinic in China. Methods and Results A total of 593 patients with movement disorders newly diagnosed in movement disorders clinic of 22 clinical medical centers from August to September in 2023 were included, including 37 patients (6.24%) with FMD and 556 patients (93.76%) with organic movement disorder. Comparison of the epidemiological characteristics of the 2 groups, the proportions of corona virus disease (COVID⁃19) infection (χ2 = 4.217, P = 0.040) and psychopsychological symptoms (χ2 = 18.694, P = 0.000) in the FMD group were higher than those in the organic movement disorder group, while age (t = 3.757, P = 0.000), age of onset (t = 3.720, P = 0.000) and proportion of hypertension (χ2 = 4.736, P = 0.030) were lower than those in the organic movement disorder group. Comparison of the clinical characteristics of the 2 groups, the FMD group had higher proportions of tremor (χ2 = 3.955, P = 0.047) and myoclonus (Fisher′s exact probability: P = 0.011) than the organic movement disorder group, and the proportions of parkinsonism (χ2 = 8.491, P = 0.004) and gait disorder (χ2 = 5.028, P = 0.025) were lower than those in the organic movement disorder group. Conclusions The age and age of onset, as well as the proportions of COVID⁃19 infection, hypertension, psychopsychological symptoms, tremor, myoclonus, parkinsonism and gait disorder with FMD were different from those with organic movement disorder in China.

وصف الملف: electronic resource

العلاقة: http://www.cjcnn.org/index.php/cjcnn/article/view/2800Test; https://doaj.org/toc/1672-6731Test

الوصول الحر: https://doaj.org/article/3a9222248783474fa033701a20b9d862Test

المؤلفون: Li Wei-Zhong, Xu Lian-Hua, Liang Chun-Bo, Wang Hua-Bin

المصدر: Zeitschrift für Kristallographie - New Crystal Structures, Vol 239, Iss 3, Pp 399-400 (2024)

مصطلحات موضوعية: 2336231, Physics, QC1-999, Crystallography, QD901-999

الوصف: C14H19N3O2, monoclinic, P21/c (no. 14), a = 8.62239(12) Å, b = 15.3515(3) Å, c = 10.86408(16) Å, β = 99.5170(14)°, V = 1418.25(4) Å3, Z = 4, Rgt (F) = 0.0452, wRref (F 2) = 0.1354, T = 295.52(10) K.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1433-7266Test; https://doaj.org/toc/2197-4578Test

الوصول الحر: https://doaj.org/article/839e56eba6564f799a15df5361a98503Test

المؤلفون: Liang Chao, Wang Hua, Tang Lixu

المصدر: 中国工程科学, Vol 25, Iss 5, Pp 30-42 (2023)

مصطلحات موضوعية: smart proactive health services, sports for health, technology system, application framework, construction ecology, Engineering (General). Civil engineering (General), TA1-2040

الوصف: The innovative application of smart proactive health services is an important component of the Healthy China initiative and an effective measure to satisfy the diversified health needs of the public in the post-epidemic era. This study focuses on building a new paradigm of smart proactive health services and aims to improve proactive health intervention and management capabilities and provide high-quality health services for the public. It analyzes the current status and challenges of proactive health services, summarizes the smart development trend, and proposes the concept of smart proactive health services. Moreover, the study constructs a technical system of smart proactive health services using a structured analysis method, establishes an application framework consisting of one center, one portal, and three endpoints, and proposes a construction ecology featuring internal and external collaboration. The application scenarios and practical cases of the smart proactive health services are summarized in terms of technology integration and smart application. Furthermore, we propose the following suggestions to promote the sustainable and high quality development of smart proactive health services in China: (1) strengthening macro policy tools to improve the development environment; (2) improving the public’s digital literacy to reshape the atmosphere for service participation; (3) building a service standards system to improve the internal digital ecology; (4) creating a multiple supply pattern to continuously improve service quality; and (5) accelerating the integration of industry, academia, research, and application to enhance the commercialization of research findings.

وصف الملف: electronic resource

العلاقة: http://www.engineering.org.cn/en/10.15302/J-SSCAE-2023.05.014Test; https://doaj.org/toc/2096-0034Test

الوصول الحر: https://doaj.org/article/ca024175ed4141128b9856b58d2180d0Test

المؤلفون: WANG Hua;WANG Meng;HUANG Shun;SUN Penghui;HU Kongzheng;XIANG Xianhong;LIN Weiyuan;ZHI Shengfang;TANG Ganghua;HAN Yanjiang

المصدر: Journal of Isotopes, Vol 36, Iss 4, Pp 397-406 (2023)

مصطلحات موضوعية: fibroblast activation protein, 18f-fapi-42, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798

الوصف: Fibroblast activation protein is highly expressed in most epithelial malignant tumors. FAP inhibitor (FAPI) has been used in the early diagnosis of tumors after radionuclide labeling. Objective to achieve automated synthesis and quality control of PET imaging agent 18F-FAPI-42. This study was based on the Allinone synthesizer and its accompanying blank kit, and 18F-FAPI-42 was prepared through one-pot reaction automation. Then, Positron Emission Tomography/Computed Tomography (PET/CT) dynamic imaging was performed on the U87-MG model mouse bearing glioblastoma to evaluate its value. The automated synthesis time of 18F-FAPI-42 was within 60 minutes, with a yield of (15.8±3.2)% (n=10, without decay correction), radiochemical purity than 95%, and specific activity of 14.52 GBq/μmol. micro PET/CT dynamic imaging showed that 18F-FAPI-42 had clear tumor development, long radiation retention time, high tumor to muscle uptake ratio, and activity time curve showed that it was mainly excreted through the kidney. The Allinone synthesizer can stably and efficiently synthesize 18F-FAPI-42 that meets drug quality control standards, and the resulting product quality meets clinical requirements. This synthesis method can provide reference and guidance for 18F labeling of NOTA modified compounds.

وصف الملف: electronic resource

العلاقة: http://www.tws.org.cn/CN/10.7538/tws.2023.36.04.0397Test; https://doaj.org/toc/1000-7512Test

الوصول الحر: https://doaj.org/article/e6bc4be823464604911c5a093fbf7a23Test

المؤلفون: An Jiang-Yong, Wang Hua-Bin, Xu Lian-Hua, Shi Ju-Mei

المصدر: Zeitschrift für Kristallographie - New Crystal Structures, Vol 239, Iss 2, Pp 187-188 (2024)

مصطلحات موضوعية: 2314318, Physics, QC1-999, Crystallography, QD901-999

الوصف: C15H16N2O, monoclinic, P21/c (no. 14), a = 5.1351(4) Å, b = 19,9377(14) Å, c = 12.3576(9) Å, β = 95.951(7)°$95.951(7){}^{\circ}$, Z = 4, V = 1258.38(16) Å3, Rgt(F) = 0.0762, wRref (F2) = 0.2224, T = 150 K.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1433-7266Test; https://doaj.org/toc/2197-4578Test

الوصول الحر: https://doaj.org/article/3487277326184b6583498cb50a443189Test

المؤلفون: Wang Hua-Bin, Xu Lian-Hua, Shi Ju-Mei, Li Wei-Zhong

المصدر: Zeitschrift für Kristallographie - New Crystal Structures, Vol 239, Iss 2, Pp 239-240 (2024)

مصطلحات موضوعية: 2322099, Physics, QC1-999, Crystallography, QD901-999

الوصف: C18H19NO3, monoclinic, P21/c (no. 14), a = 8.9529(3) Å, b = 13.5984(4) Å, c = 12.8403(5) Å, β = 101.572(4)°, Rgt(F) = 0.0458, wRref(F2) = 0.1395, V = 1532.54(9) Å3, Z = 4, T = 150 K.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1433-7266Test; https://doaj.org/toc/2197-4578Test

الوصول الحر: https://doaj.org/article/4f06726422604aa89565c4803412cdf8Test