نتائج البحث - "Vinod K. Prasad"

الوصف: Unlike unrelated donor registries, transplant centers lack uniform approaches to related donor assessment and deferral. To test whether related donors are at increased risk for donation-related toxicities, we conducted a prospective observational trial of 11,942 related and unrelated donors aged 18–60 years. Bone marrow (BM) was collected at 37 transplant and 78 National Marrow Donor Program centers, and peripheral blood stem cells (PBSC) were collected at 42 transplant and 87 unrelated donor centers in North America. Possible presence of medical comorbidities was verified prior to donation, and standardized pain and toxicity measures were assessed pre-donation, peri-donation, and one year following. Multivariate analyses showed similar experiences for BM collection in related and unrelated donors; however, related stem cell donors had increased risk of moderate [odds ratios (ORs) 1.42; P

وصف الملف: electronic resource

العلاقة: https://haematologica.org/article/view/8859Test; https://doaj.org/toc/0390-6078Test; https://doaj.org/toc/1592-8721Test

الوصول الحر: https://doaj.org/article/fdcd298454b34e89b6d33b8ea6f81372Test

View record in DOAJ

النص الكامل

4

دورية أكاديمية

Disseminated Adenovirus Infection After Combined Liver-Kidney Transplantation

المؤلفون: Marion Hemmersbach-Miller, Emily S. Bailey, Matthew Kappus, Vinod K. Prasad, Gregory C. Gray, J. Andrew Alspaugh

المصدر: Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)

مصطلحات موضوعية: adenovirus, transplantation, immunocompromised host, brincidofovir, epidemiology, Microbiology, QR1-502

الوصف: Human adenovirus (HAdV) infections are well-described after hematopoietic stem cell transplantation but less well understood in solid organ transplantation (SOT). We describe a case of disseminated HAdV type 21 infection 5 months after combined liver-kidney transplantation, expanding the limited literature describing this infection in the SOT population.

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/article/10.3389/fcimb.2018.00408/fullTest; https://doaj.org/toc/2235-2988Test

الوصول الحر: https://doaj.org/article/773f7f4ee73a4843ba442664f3f5bf36Test

View record in DOAJ

النص الكامل

5

Allogenic Hematopoietic Cell Transplantations Are Effective in Patients with p47phox Chronic Granulomatous Disease: A Primary Immune Deficiency Treatment Consortium Study

المؤلفون: Eyal Grunebaum, Danielle E. Arnold, Brent Logan, Suhag Parikh, Rebecca A. Marsh, Linda M. Griffith, Kanwaldeep Mallhi, Deepak Chellapandian, Stephanie Si Lim, Christin L. Deal, Luis Murguía-Favela, Talal I. Mousallem, Prof. Vinod K. Prasad, Pierre Teira, Fabien Touzot, Nancy J. Bunin, Jennifer R. Heimall, Lauri M. Burroughs, Malika Kapadia, Susan Prockop, Sharat Chandra, Shanmuganathan Chandrakasan, Sonali Chaudhury, Larisa Broglie, Richard J. O’Reilly, Blachy J. Dávila Saldaña, Edo Schaefer, Hey Chong, Jeffrey J. Bednarski, Ahmad Rayes, Kenneth DeSantes, Donald B. Kohn, Luigi D. Notarangelo, Sung-Yun Pai, Jennifer Puck, Troy Torgerson, Morton J. Cowan, Christopher C. Dvorak, Lisa Forbes Satter, Elie Haddad, Michael Pulsipher, Harry L. Malech, Elizabeth M. Kang, Jennifer W. Leiding

المصدر: Transplantation and Cellular Therapy. 29:S289-S290

مصطلحات موضوعية: Transplantation, Molecular Medicine, Immunology and Allergy, Cell Biology, Hematology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::37a5ec26156f675b8a4efee7c33563c8Test
https://doi.org/10.1016/s2666-6367Test(23)00451-7

6

Comparison of Outcomes in Patients with Cerebral Adrenoleukodystrophy (CALD) Receiving Elivaldogene Autotemcel (eli-cel; Lenti-D) Gene Therapy in Clinical Trials Versus Those Receiving Allogeneic Hematopoietic Stem Cell Transplant in a Contemporaneous Comparator Study

المصدر: Transplantation and Cellular Therapy. 28:S2-S4

مصطلحات موضوعية: Transplantation, Molecular Medicine, Immunology and Allergy, Cell Biology, Hematology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::18b46d4287bb7aff695cf8f2232f64b4Test
https://doi.org/10.1016/s2666-6367Test(22)00164-6

7

Hematopoietic Cell Transplantation in 240 Patients with Chronic Granulomatous Disease: A Pidtc Report

المؤلفون: Danielle E. Arnold, Suhag Parikh, Brent Logan, Rebecca Marsh, Linda M. Griffith, Ruizhe Wu, Kanwaldeep Mallhi, Deepak Chellapandian, Stephanie Si, Eyal Grunebaum, Larisa Broglie, Vinod K. Prasad, Jennifer Heimall, Nancy J. Bunin, Pierre Teira, Fabien Touzot, Lauri M. Burroughs, Aleksandra Petrovic, Jack J. Bleesing, Sharat Chandra, Neena Kapoor, Jasmeen Dara, Morna Dorsey, Olatundun Williams, Malika Kapadia, Jeffrey Bednarski, Ahmad Rayes, Karin Chen, Hey Chong, Geoff D.E. Cuvelier, Lisa R. Forbes, Caridad Martinez, Mark T. Vander Lugt, Lolie C. Yu, Shanmuganathan Chandrakasan, Avni Joshi, Susan E. Prockop, Blachy J. Davila Saldana, Victor Aquino, Christen L. Ebens, Lisa Madden, Kenneth DeSantes, Jordan Milner, Hemalatha G. Rangarajan, Ami J Shah, Alfred P. Gillio, Alan P. Knutsen, Holly K. Miller, Theodore B. Moore, Nicola Wright, Morton J. Cowan, Christopher C. Dvorak, Elie Haddad, Donald B. Kohn, Luigi D. Notarangelo, Sung-Yun Pai, Jennifer Puck, Mike A. Pulsipher, Troy Torgerson, Harry L. Malech, Elizabeth M. Kang, Jennifer W. Leiding

المصدر: Transplantation and Cellular Therapy. 28:S101-S103

مصطلحات موضوعية: Transplantation, Molecular Medicine, Immunology and Allergy, Cell Biology, Hematology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::3da9f936473cbe58a610995dd7ab103aTest
https://doi.org/10.1016/s2666-6367Test(22)00286-x

8

Contemporary Comparison of Alternative Donor Transplantation Sources for Pediatric Hemophagocytic Lymphohistiocytosis Demonstrates Effective Outcomes for Umbilical Cord Blood Grafts: A Single Center Experience

المؤلفون: Dr. Taymour Hammoudi, Lauren A Stafford, Tonya Jolly, Andrea Bauchat, Timothy Alan Driscoll, Vinod K Prasad, Paul L. Martin

المصدر: Transplantation and Cellular Therapy. 29:S301

مصطلحات موضوعية: Transplantation, Molecular Medicine, Immunology and Allergy, Cell Biology, Hematology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::77436947920bd4a6b555b567e798e07fTest
https://doi.org/10.1016/s2666-6367Test(23)00466-9

9

Contemporary Comparison of Alternative Donor Transplantation Sources with Matched Related Donors for Pediatric Severe Aplastic Anemia Demonstrates Non-Inferior Outcomes: A Single Center Experience

المؤلفون: Dr. Taymour Hammoudi, Lauren A. Stafford, Tonya Jolly, Andrea Bauchat, Timothy Alan Driscoll, Vinod K Prasad, Paul L. Martin

المصدر: Transplantation and Cellular Therapy. 29:S155

مصطلحات موضوعية: Transplantation, Molecular Medicine, Immunology and Allergy, Cell Biology, Hematology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::63dc427019d34f42fefb2961b439d5a6Test
https://doi.org/10.1016/s2666-6367Test(23)00266-x

10

The critical role of psychosine in screening, diagnosis, and monitoring of Krabbe disease

المصدر: Genetics in Medicine. 22:1108-1118

الوصف: Newborn screening (NBS) for Krabbe disease (KD) is performed by measurement of galactocerebrosidase (GALC) activity as the primary test. This revealed that GALC activity has poor specificity for KD. Psychosine (PSY) was proposed as a disease marker useful to reduce the false positive rate for NBS and for disease monitoring. We report a highly sensitive PSY assay that allows identification of KD patients with minimal PSY elevations. PSY was extracted from dried blood spots or erythrocytes with methanol containing d5-PSY as internal standard, and measured by liquid chromatography–tandem mass spectrometry. Analysis of PSY in samples from controls (N = 209), GALC pseudodeficiency carriers (N = 55), GALC pathogenic variant carriers (N = 27), patients with infantile KD (N = 26), and patients with late-onset KD (N = 11) allowed for the development of an effective laboratory screening and diagnostic algorithm. Additional longitudinal measurements were used to track therapeutic efficacy of hematopoietic stem cell transplantion (HSCT). This study supports PSY quantitation as a critical component of NBS for KD. It helps to differentiate infantile from later onset KD variants, as well as from GALC variant and pseudodeficiency carriers. Additionally, this study provides further data that PSY measurement can be useful to monitor KD progression before and after treatment.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47210c51ffe5b05fc9c0888ea3c4791Test
https://doi.org/10.1038/s41436-020-0764-yTest

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