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المؤلفون: Alison E. Ringel, Vincent Frappier, Leonard Guarente, Cynthia Wolberger, Caitlin R. Ondracek
المساهمون: Massachusetts Institute of Technology. Department of Biology, Frappier, Vincent
المصدر: Cell Reports, Vol 18, Iss 10, Pp 2310-2319 (2017)
Elsevierمصطلحات موضوعية: 0301 basic medicine, SIRT3, Sir2, Mutant, predictive protein modeling, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, SIRT1, NAD+, lcsh:QH301-705.5, chemistry.chemical_classification, 030102 biochemistry & molecular biology, biology, aging, adaptive mutations, kinetic analyses, yeast replicative lifespan, enzymes and coenzymes (carbohydrates), 030104 developmental biology, Enzyme, lcsh:Biology (General), chemistry, Biochemistry, Acetylation, Sirtuin, biology.protein, NAD+ kinase, Genetic screen, Protein deacetylation
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a8a7f0b89530a57b4ec2b7e3f08eb8Test
https://doi.org/10.1016/j.celrep.2017.02.031Test -
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المساهمون: Massachusetts Institute of Technology. Department of Biology, Massachusetts Institute of Technology. Department of Biological Engineering, Koch Institute for Integrative Cancer Research at MIT
المصدر: PMC
مصطلحات موضوعية: Protein Conformation, alpha-Helical, Computer science, Protein Data Bank (RCSB PDB), Gene Expression, Sequence (biology), Peptide, Peptide binding, Crystallography, X-Ray, Protein Engineering, 0302 clinical medicine, Protein sequencing, Structural Biology, Statistics, Cloning, Molecular, Structural motif, Conformational isomerism, chemistry.chemical_classification, 0303 health sciences, 030302 biochemistry & molecular biology, computer.file_format, Recombinant Proteins, Molecular Docking Simulation, Proto-Oncogene Proteins c-bcl-2, Thermodynamics, Protein Binding, Protein design, Genetic Vectors, Saccharomyces cerevisiae, Article, Protein–protein interaction, Minor Histocompatibility Antigens, 03 medical and health sciences, Structure-Activity Relationship, Humans, Protein Interaction Domains and Motifs, Amino Acid Sequence, Molecular Biology, 030304 developmental biology, Binding Sites, Atomic coordinates, Protein engineering, Protein Data Bank, Sequence identity, Term (time), Protein Structure, Tertiary, chemistry, Myeloid Cell Leukemia Sequence 1 Protein, Peptides, computer, Sequence Alignment, 030217 neurology & neurosurgery, Protein ligand
وصف الملف: application/pdf; application/octet-stream
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f83dd6352e1d801006c4f8859a872b4aTest
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المؤلفون: François Major, Vincent Frappier, Rafael Najmanovich, Olivier Mailhot
مصطلحات موضوعية: Physics, 0303 health sciences, Sequence, Conformational change, Anisotropic Network Model, 030302 biochemistry & molecular biology, Protein Data Bank (RCSB PDB), RNA, computer.file_format, Bioinformatics, Protein Data Bank, Measure (mathematics), 03 medical and health sciences, Nucleic acid, Biological system, computer, 030304 developmental biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5098ea499b607a53d0077081b68e3f82Test
https://doi.org/10.1101/198531Test -
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المؤلفون: Vincent Frappier, Matthieu Chartier, Rafael Najmanovich
المصدر: Nucleic Acids Research
مصطلحات موضوعية: Models, Molecular, Web server, Protein Conformation, Entropy, Biology, computer.software_genre, Vibration, Protein structure, Normal mode, Genetics, Entropy (information theory), Web Server issue, Point Mutation, Conformational ensembles, Thermostability, Quantitative Biology::Biomolecules, Internet, Protein Stability, Protein dynamics, Point mutation, Temperature, Quantitative Biology::Genomics, Biochemistry, Biological system, computer, Software
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb93f4db13e3f749419db98c400de869Test
http://europepmc.org/articles/PMC4489264Test -
25
المؤلفون: Rafael Najmanovich, Vincent Frappier
المصدر: Protein Science. 24:474-483
مصطلحات موضوعية: chemistry.chemical_classification, Thermophile, Thermodynamics, Protein engineering, Biology, Elastic network, Biochemistry, Amino acid, Crystallography, chemistry, Atomic contact, Vibrational entropy, Molecular Biology, Mesophile, Thermostability
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c887811c6ad9374b8cbc007df3fdb6b2Test
https://doi.org/10.1002/pro.2592Test -
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المؤلفون: Vincent, Frappier, Matthieu, Chartier, Rafael, Najmanovich
المصدر: Methods in molecular biology (Clifton, N.J.). 1529
مصطلحات موضوعية: Models, Molecular, Protein Conformation, Protein Stability, Mutation, Computational Biology, Proteins, Thermodynamics, Computer Simulation, Web Browser, Protein Engineering, Software
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::39d8f18b59274d77183be963d303d4fcTest
https://pubmed.ncbi.nlm.nih.gov/27914052Test -
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المؤلفون: Vincent Frappier, Matthieu Chartier, Rafael Najmanovich
المصدر: Methods in Molecular Biology ISBN: 9781493966356
مصطلحات موضوعية: 0301 basic medicine, Flexibility (engineering), Quantitative Biology::Biomolecules, 030102 biochemistry & molecular biology, Computer science, Protein dynamics, Protein design, Stability (learning theory), Computational biology, Protein engineering, 03 medical and health sciences, 030104 developmental biology, Protein stability, Normal mode, Biological system, Conformational ensembles
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::8876f596d1be7b7eda53398cea035b74Test
https://doi.org/10.1007/978-1-4939-6637-0_9Test -
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المؤلفون: Caitlin R, Ondracek, Vincent, Frappier, Alison E, Ringel, Cynthia, Wolberger, Leonard, Guarente
المصدر: Cell reports. 18(10)
مصطلحات موضوعية: Models, Molecular, Kinetics, Sirtuin 2, Sequence Homology, Amino Acid, Protein Stability, Mutation, Humans, Acetylation, Saccharomyces cerevisiae, NAD, Article, Substrate Specificity
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::eb5c9ae7520d04b7688f4133a73b5928Test
https://pubmed.ncbi.nlm.nih.gov/28273448Test -
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المؤلفون: Jean-Guy Lehoux, Vincent Frappier, Pierre Lavigne, Aurélien Lorin, Andrée Lefebvre, Rafael Najmanovich, Francis Gaudreault, Danny Létourneau
المصدر: Journal of Lipid Research, Vol 53, Iss 12, Pp 2677-2689 (2012)
مصطلحات موضوعية: Models, Molecular, Circular dichroism, Magnetic Resonance Spectroscopy, Stereochemistry, Protein domain, STARD4, QD415-436, Cholic Acid, Chenodeoxycholic Acid, Ligands, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Endocrinology, Chenodeoxycholic acid, Humans, Cloning, Molecular, Binding site, Research Articles, bile acids, lipid transport, Binding Sites, Protein Stability, Isothermal titration calorimetry, Cell Biology, Reference Standards, isothermal titration calorimetry, circular dichroism, Adaptor Proteins, Vesicular Transport, chemistry, cholesterol metabolism, Thermodynamics, Farnesoid X receptor, Carrier Proteins, steroidogenic acute regulatory protein, Heteronuclear single quantum coherence spectroscopy
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ce6728e3f4b8348c0e3aca5120b3bd1Test
https://doi.org/10.1194/jlr.m031245Test -
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المؤلفون: Vincent Frappier, Martin Montagne, François-Olivier McDuff, Marie-Eve Beaulieu, Pierre Lavigne, Jean-François Naud
المصدر: Journal of Molecular Recognition. 25:414-426
مصطلحات موضوعية: Residue (chemistry), Molecular recognition, Zipper, Double mutant, Structural Biology, Chemistry, Stereochemistry, Helix, Sequence (biology), Molecular Biology, Transcription factor, In vitro
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4e44f21cc0f04941d2794f62fd4af2afTest
https://doi.org/10.1002/jmr.2203Test