المؤلفون: Azevedo, Alline dos Reis Castro, Corrêa, Glaucy Rejani Amarante, Moreira, Antonio Carlos Laender

المصدر: Research, Society and Development; Vol. 11 No. 15; e54111536968 ; Research, Society and Development; Vol. 11 Núm. 15; e54111536968 ; Research, Society and Development; v. 11 n. 15; e54111536968 ; 2525-3409

مصطلحات موضوعية: Toxoplasma gondii, Toxoplasmosis, Ocular, Chorioretinitis, Uveitis, posterior, Toxoplasmosis ocular, Coriorretinitis, Uveítis posterior, Toxoplasmose ocular, Coriorretinite, Uveíte posterior

الوصف: A toxoplasmose é uma doença de origem infecciosa causada pelo protozoário Toxoplasma gondii e é responsável por diversas manifestações sistêmicas, seguindo um quadro clínico leve a grave de febre, dores musculares, linfonodomegalia, comprometimento neural e lesões oculares. A toxoplasmose ocular é responsável por gerar um comprometimento da mácula, do nervo óptico, da úvea posterior, gerando a uveíte posterior, e, principalmente, retinocoroidite. O toxoplasma é responsável por 50% dos casos de uveítes no Brasil. Portanto, este artigo tem como objetivo revisar a literatura acerca das principais manifestações oculares da toxoplasmose sistêmica, focando em prevalência, incidência, sinais e sintomas e principais métodos de abordagem. Trata-se de uma revisão integrativa da literatura e para a realização das pesquisas foram utilizadas as seguintes bases de dados: PUBMED, SCIELO e BVS. O processo de triagem contou com os seguintes critérios de inclusão: artigos que respondessem à questão norteadora, em inglês, português ou espanhol, e entre 2017 a 2021. Após as pesquisas, foram obtidos um total de 12 artigos para revisão. O Toxoplasma gondii é responsável pelo processo inflamatório granulomatoso secundário na coroide e, após a fase aguda, pode-se apresentar como uma cicatriz coriorretiniana com centro branco e bordas pigmentadas como complicação, sendo as principais manifestações oculares: retinocoroidite, papilite, neurorretinite e a esclerite. Como consequência desse trofismo ocular, o toxoplasma pode gerar redução da acuidade visual, em sua maioria menor ou igual a 20/200, evolução para perda visual parcial ou cegueira, presença de moscas volantes, pressão intraocular aumentada, fotofobia, hiperemia, simulando uma conjuntivite e turvação visual. A principal população acometida é a de baixo desenvolvimento socioeconômico e baixa escolaridade estando associados a um risco de maior exposição ao agente etiológico. Portanto, o presente estudo reafirma a necessidade de dar seguimento com novos estudos, a fim de prevenir ...

وصف الملف: application/pdf

العلاقة: https://rsdjournal.org/index.php/rsd/article/view/36968/30765Test; https://rsdjournal.org/index.php/rsd/article/view/36968Test

الإتاحة: https://doi.org/10.33448/rsd-v11i15.36968Test
https://rsdjournal.org/index.php/rsd/article/view/36968Test

المؤلفون: Dominika Pohlmann, Martin Berlin, Felix Reidl, Steffen Emil Künzel, Uwe Pleyer, Antonia M. Joussen, Sibylle Winterhalter

المصدر: Journal of Clinical Medicine; Volume 11; Issue 18; Pages: 5376

مصطلحات موضوعية: artifacts, longitudinal, optical coherence tomography angiography, uveitis posterior

الوصف: Background: Knowledge about artifacts in optical coherence tomography angiography (OCTA) is important to avoid misinterpretations. An overview of possible artifacts in posterior uveitis provides important information for interpretations. Methods: In this monocentric prospective study, OCTA images from a total of 102 eyes of 54 patients with posterior uveitis, and an age-matched control group including 34 healthy subjects (67 eyes), were evaluated (day 0, month 3, month 6). We assigned different artifacts to distinct layers. Various types of artifacts were examined in different retinal layers. The χ2 test for the comparison between the control and uveitis group and Cochran’s Q test for the longitudinal comparison within the uveitis group were used. Results: A total of 2238 images were evaluated; 1836 from uveitis patients and 402 from healthy subjects. A total of 2193 artifacts were revealed. Projection (812 [36.3%]), segmentation (579 [25.9%]), shadowing (404 [18.1%]), and blink artifacts (297 [13.3%]) were the most common artifact types. The uveitis group displayed significantly more segmentation artifacts and projection artifacts (p < 0.001). No segmentation artifacts were documented in healthy subjects. The consecutive examinations within the uveitis group revealed the same artifact types without significance (p > 0.1). Conclusions: The uveitis patients showed more segmentation and projection artifacts than the control group. Within the uveitis group, artifacts remained longitudinally constant in terms of artifact type and pattern. The artifacts therefore appear to be reproducible on an individual level.

وصف الملف: application/pdf

العلاقة: Ophthalmology; https://dx.doi.org/10.3390/jcm11185376Test

الإتاحة: https://doi.org/10.3390/jcm11185376Test

المؤلفون: Patricio J. Rodríguez-Valdés, Angelina Espino-Barros-Palau

المصدر: Revista Mexicana de Oftalmología, Vol 96, Iss 2 (2022)

مصطلحات موضوعية: Sífilis. Enfermedad de transmisión sexual. Sífilis ocular. Coriorretinitis placoide. Uveítis posterior, Ophthalmology, RE1-994

الوصف: Introducción: La sífilis es una enfermedad de transmisión sexual ocasionada por la espiroqueta Treponema pallidum. La afectación ocular usualmente se presenta en la sífilis secundaria o terciaria, y puede afectar tanto el segmento anterior como el segmento posterior del ojo. La coriorretinitis placoide sifilítica aguda (CPSA) es una presentación ocular recientemente descrita, en la cual se encuentran lesiones placoides grandes, amarillas, circulares u ovaladas, en el epitelio pigmentario retiniano, en o cerca de la mácula. Caso clínico: Describimos el caso de un paciente de 37 años que presenta CPSA bilateral y secuencial. No tenía diagnóstico previo de sífilis y se encontraba bajo tratamiento inmunosupresor para artritis psoriásica. Presentó pérdida visual bilateral, secuencial, grave, asociada a los hallazgos característicos de CPSA. La serología para sífilis confirmó el diagnóstico y se indicó tratamiento con antibiótico intravenoso, con el apoyo del infectólogo. El paciente respondió favorablemente al tratamiento, con importante mejoría de su agudeza visual. Los oftalmólogos debemos conocer esta presentación poco conocida de la sífilis ocular.

العلاقة: https://www.rmo.com.mx/frame_esp.php?id=246Test; https://doaj.org/toc/0187-4519Test; https://doaj.org/article/71f64e7a70104fe88378989bfc7b2788Test

الإتاحة: https://doi.org/10.24875/RMO.M22000216Test
https://doaj.org/article/71f64e7a70104fe88378989bfc7b2788Test

المؤلفون: Paiva, Alexandre de Carvalho Mendes, Britto, Vinícius Secchim de, Criado, Guilherme Garcia, Simões, Kelma Macedo Pohlmann, Motta, Mário Martins dos Santos

المصدر: Revista Brasileira de Oftalmologia. January 2021 80(4)

مصطلحات موضوعية: Syphilis, Neurosyphilis, Uveitis, posterior, Night blindness, Retinitis pigmentosa

الوصف: Syphilis is a sexually transmitted infection caused by the spirochete Treponema pallidum. Ocular involvement can occur at any time, and it may affect 10% of patients in the secondary stage, and from 2% to 5% in the tertiary stage. Uveitis is the most common presentation of ocular syphilis, affecting 0.4% to 8% of patients with systemic disease. Chorioretinitis is the most common posterior alteration. We present the case of a 53-year-old male patient, presenting with bilateral low visual acuity and nyctalopia for 3 years. His physical examination revealed decreased pupillary reflex, anterior vitreous cells, physiologic papillae, arteriolar attenuation, reduced foveal reflex, diffuse retinal pigment epithelium atrophy, peripapillary and perivascular punctate pigment accumulation and peripheral chorioretinitis. Full-field electroretinogram was extinct in both eyes. Treponemal syphilis test was positive. Previously diagnosed as retinitis pigmentosa, evolved to blindness, despite proper treatment. Our case shows syphilis as a significant cause of blindness. Atypical presentations of retinitis pigmentosa must warn ophthalmologists to etiologies of pseudoretinitis pigmentosa, such as syphilis.

وصف الملف: text/html

الوصول الحر: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802021000400507Test

المؤلفون: Ying, Juni Eyat Juni, Tang, Chin Shi, Hanapi, Maya Sapira, Ngoo, Qi Zhe, Hitam, Wan Hazabbah Wan

المصدر: Revista Brasileira de Oftalmologia. January 2021 80(4)

مصطلحات موضوعية: Choroid diseases/diagnosis, Tuberculoma, Tuberculosis, ocular, Uveitis, posterior

الوصف: Choroidal tuberculomas are present in patients with ocular tuberculosis. They usually occur in a patient with previous history of tuberculosis, and are rarely the initial presentation, with no prior systemic manifestations. We present a patient with unilateral choroidal tuberculoma as the initial presentation of presumed ocular tuberculosis, which enabled earlier initiation of treatment.

وصف الملف: text/html

الوصول الحر: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802021000400501Test

المؤلفون: Alexandre de Carvalho Mendes Paiva, Vinícius Secchim de Britto, Guilherme Garcia Criado, Kelma Macedo Pohlmann Simões, Mário Martins dos Santos Motta

المصدر: Revista Brasileira de Oftalmologia, Vol 80, Iss 4 (2021)

مصطلحات موضوعية: Syphilis, Neurosyphilis, Uveitis, posterior, Night blindness, Retinitis pigmentosa, Ophthalmology, RE1-994

الوصف: ABSTRACT Syphilis is a sexually transmitted infection caused by the spirochete Treponema pallidum. Ocular involvement can occur at any time, and it may affect 10% of patients in the secondary stage, and from 2% to 5% in the tertiary stage. Uveitis is the most common presentation of ocular syphilis, affecting 0.4% to 8% of patients with systemic disease. Chorioretinitis is the most common posterior alteration. We present the case of a 53-year-old male patient, presenting with bilateral low visual acuity and nyctalopia for 3 years. His physical examination revealed decreased pupillary reflex, anterior vitreous cells, physiologic papillae, arteriolar attenuation, reduced foveal reflex, diffuse retinal pigment epithelium atrophy, peripapillary and perivascular punctate pigment accumulation and peripheral chorioretinitis. Full-field electroretinogram was extinct in both eyes. Treponemal syphilis test was positive. Previously diagnosed as retinitis pigmentosa, evolved to blindness, despite proper treatment. Our case shows syphilis as a significant cause of blindness. Atypical presentations of retinitis pigmentosa must warn ophthalmologists to etiologies of pseudoretinitis pigmentosa, such as syphilis.

وصف الملف: electronic resource

العلاقة: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802021000400507&tlng=enTest; https://doaj.org/toc/1982-8551Test

الوصول الحر: https://doaj.org/article/352e244c69314f2bbce9aa96cdee3c8fTest

المؤلفون: Juni Eyat Juni Ying, Chin Shi Tang, Maya Sapira Hanapi, Qi Zhe Ngoo, Wan Hazabbah Wan Hitam

المصدر: Revista Brasileira de Oftalmologia, Vol 80, Iss 4 (2021)

مصطلحات موضوعية: Choroid diseases/diagnosis, Tuberculoma, Tuberculosis, ocular, Uveitis, posterior, Ophthalmology, RE1-994

الوصف: ABSTRACT Choroidal tuberculomas are present in patients with ocular tuberculosis. They usually occur in a patient with previous history of tuberculosis, and are rarely the initial presentation, with no prior systemic manifestations. We present a patient with unilateral choroidal tuberculoma as the initial presentation of presumed ocular tuberculosis, which enabled earlier initiation of treatment.

وصف الملف: electronic resource

العلاقة: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802021000400501&tlng=enTest; https://doaj.org/toc/1982-8551Test

الوصول الحر: https://doaj.org/article/6ce35f64682f4beeadd687bc6ae1068aTest

المؤلفون: Rodríguez-Valdés,Patricio J., Espino-Barros-Palau,Angelina

المصدر: Revista mexicana de oftalmología v.96 n.2 2022

مصطلحات موضوعية: Sífilis, Enfermedad de transmisión sexual, Sífilis ocular, Coriorretinitis placoide, Uveítis posterior

الوصف: Resumen Introducción: La sífilis es una enfermedad de transmisión sexual ocasionada por la espiroqueta Treponema pallidum. La afectación ocular usualmente se presenta en la sífilis secundaria o terciaria, y puede afectar tanto el segmento anterior como el segmento posterior del ojo. La coriorretinitis placoide sifilítica aguda (CPSA) es una presentación ocular recientemente descrita, en la cual se encuentran lesiones placoides grandes, amarillas, circulares u ovaladas, en el epitelio pigmentario retiniano, en o cerca de la mácula. Caso clínico: Describimos el caso de un paciente de 37 años que presenta CPSA bilateral y secuencial. No tenía diagnóstico previo de sífilis y se encontraba bajo tratamiento inmunosupresor para artritis psoriásica. Presentó pérdida visual bilateral, secuencial, grave, asociada a los hallazgos característicos de CPSA. La serología para sífilis confirmó el diagnóstico y se indicó tratamiento con antibiótico intravenoso, con el apoyo del infectólogo. El paciente respondió favorablemente al tratamiento, con importante mejoría de su agudeza visual. Los oftalmólogos debemos conocer esta presentación poco conocida de la sífilis ocular.

وصف الملف: text/html

الإتاحة: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S2604-12272022000200098Test

المؤلفون: Deepak Soni, Bhavana Sharma, Samendra Karkhur

المصدر: BMJ Case Rep

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Choroidal granuloma, Visual acuity, Choroiditis, Case Report, Tuberculosis, Ocular, Uveitis, 03 medical and health sciences, 0302 clinical medicine, Posterior scleritis, Medicine, Humans, business.industry, Uveitis, Posterior, General Medicine, medicine.disease, Dermatology, Posterior uveitis, Granuloma, 030221 ophthalmology & optometry, Etiology, medicine.symptom, Neoplasm Recurrence, Local, business, 030217 neurology & neurosurgery

الوصف: Intraocular tuberculosis has protean clinical manifestations and remains an important etiological differential for uveitis in an endemic region. A 27-year-old male presented with visual acuity of counting fingers close to face in right (OD) and 20/25 in left eye (OS). Examination revealed a choroidal granuloma in OS and healed serpiginous-like choroiditis in OD. Antitubercular therapy was started with systemic corticosteroids. Granuloma resolved completely; however, the patient presented with neuroretinitis and posterior scleritis, as first and second recurrence, respectively, within a oneyear period. These were managed with systemic corticosteroids and immunosuppressive therapy was added, after second recurrence. The patient responded well and maintains remission. This case presented a clinical challenge with distinct recurrence patterns of tubercular posterior uveitis in the same eye, which has not been reported before. Successful management entailed use of antitubercular therapy, corticosteroids, and immunosuppressive therapy in a step-ladder approach, resulting in preservation of vision and achieving long-term remission.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c43a2c161e905863cbb0448ed15b43Test
https://pubmed.ncbi.nlm.nih.gov/34162610Test

المؤلفون: Sunil James, Karunakaran Pradeep Thozhuthumparambil

المصدر: BMJ Case Rep

مصطلحات موضوعية: medicine.medical_specialty, Lymphocytic meningitis, Optic Disk, Case Report, 03 medical and health sciences, 0302 clinical medicine, Cerebrospinal fluid, medicine, Humans, Meningitis, Syphilis, Pseudotumor Cerebri, business.industry, Cranial nerves, Uveitis, Posterior, General Medicine, Middle Aged, medicine.disease, eye diseases, Surgery, Posterior uveitis, 030221 ophthalmology & optometry, Optic disc swelling, Female, Presentation (obstetrics), business, 030217 neurology & neurosurgery, Papilledema

الوصف: Idiopathic intracranial hypertension (IIH) is being diagnosed more often in the UK due to the rise in obesity. In fact, patients who present with bilateral optic disc swelling are habitually put on the papilloedema pathway, often without consideration of other diagnoses. We report the case of a middle-aged woman diagnosed with papilloedema and managed as IIH, until, cerebrospinal fluid (CSF) analysis revealed evidence of lymphocytic meningitis secondary to syphilis. The patient was treated successfully with intravenous antibiotics. Syphilis is the great masquerader and should be a diagnosis to consider in patients who have CSF findings incongruent with their clinical presentation.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8a60902eca587eacaded7ded49fed2Test
https://pubmed.ncbi.nlm.nih.gov/34011659Test