المؤلفون: Noriyuki Nishiwaki, Yoshihiro Mikuriya, Fumiaki Takatsu, Ryoji Ochiai, Tomokazu Kakishita, Naruyuki Kobayashi, Takaya Kobatake, Shinji Hato, Norihiro Teramoto, Mototsugu Nagao, Izumi Fukuda, Koji Ohta

المصدر: Surgical Case Reports, Vol 9, Iss 1, Pp 1-6 (2023)

مصطلحات موضوعية: Liposarcoma, Insulin-like growth factor, Hypoglycemia, Surgery, RD1-811

الوصف: Abstract Background Tumor-produced high molecular weight insulin-like growth factor-II (big insulin-like growth factor-II) is considered to cause non-islet cell tumor hypoglycemia. This paper presents a case of surgically resected retroperitoneal liposarcoma that produced big insulin-like growth factor-II. Case presentation Here, we report the case of a 62-year-old woman who presented with an abdominal mass and hypoglycemia. Non-islet cell tumor hypoglycemia due to retroperitoneal liposarcoma was suspected. After complete resection of the tumor, the patient’s hypoglycemia improved and big insulin-like growth factor-II disappeared in the molecular weight analysis of serum insulin-like growth factor-II by western blotting. The patient had no tumor recurrence or reappearance of hypoglycemia 16 months after the operation without any adjuvant therapy. Conclusions Although insulin-like growth factor-II-producing tumors are generally large and difficult to operate on, surgical resection is currently the most effective and only treatment; thus, it is essential to attempt resection aggressively.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2198-7793Test

الوصول الحر: https://doaj.org/article/40db2401462546aca3915da0fc7a99c4Test

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المصدر: 日本臨床外科学会雑誌 / Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association). 2020, 81(6):1029

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المصدر: 日本臨床外科学会雑誌 / Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association). 2010, 71(2):541

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