المؤلفون: Spaegele, Nina, Ditzer, Julia, Rodrigues, Mariana, Talmon, Anat

المساهمون: Technische Universität Dresden

المصدر: BMC Pregnancy and Childbirth ; volume 24, issue 1 ; ISSN 1471-2393

مصطلحات موضوعية: Obstetrics and Gynecology

الوصف: Background Preterm birth, which occurs when a baby is born before 37 weeks, has enormous implications for public health. It is the leading cause of infant death and mortality in children under the age of five. Unfortunately, the multifaceted causes of preterm birth are not fully understood. One construct that has received increasing attention in women’s transition to motherhood is body boundaries, i.e., the metaphorical barriers that separate the self from the outer, surrounding “not self.” This study aims to examine the role of well-defined and disturbed body boundaries in predicting preterm birth. Methods A sample of 655 Israeli pregnant women reported their sense of body boundaries (BBS, as measured by the Sense of Body Boundaries Survey) pre- and postnatally. We performed a General Linear Model (GLM) testing the effect of the BBS total score on the days women delivered before their due date and controlling for whether it was the women’s first child. Results Our GLMs controlling for whether it was the women’s first child showed that the BBS total mean exhibited a significant predictive effect on the number of days delivered before the due date ( F (57,313) = 3.65, p < .001). Conclusions These results demonstrate heterogeneity in women’s sense of body boundaries during pregnancy and are the first to disentangle a link between disturbed body boundaries and preterm birth. Mediating mechanisms in this relation, e.g., psychosocial stress, as well as clinical implications are discussed in detail.

الإتاحة: https://doi.org/10.1186/s12884-023-06203-2Test

المؤلفون: Lewin, Tova, Spaegele, Nina, Attrash-Najjar, Afnan, Katz, Carmit, Talmon, Anat

المصدر: Journal of Sexual Aggression ; volume 29, issue 3, page 327-342 ; ISSN 1355-2600 1742-6545

الإتاحة: https://doi.org/10.1080/13552600.2023.2197929Test

المؤلفون: Spägele, Nina

المساهمون: female, N.N.

مصطلحات موضوعية: risk prediction, biomarkers, mortality, ddc:610

الوصف: Theoretical Background. The prevalence of non-communicable diseases are continuously increasing requiring simple and inexpensive ways to identify individuals at risk for developing these disorders to target with preventive approaches. Study Aims. The current study aims to introduce a novel biomarker-based risk indicator, to link this novel tool to commonly recognized health risk factors, to relate it to current disease burden, and to prospectively identify individuals at risk for premature mortality and reduced everyday functioning. Methods. K-mean clusters were identified based on C-reactive protein (CRP), interleukin-6 (IL-6), fibrinogen, cortisol, and creatinine concentrations in a U.S. American sample (N=1,234) and validated in a Japanese sample (N=378). The association of the resulting clusters with biological sex, age, body mass index (BMI), physical activity, alcohol, and smoking habits as well as early-life stress were examined. Odds ratios for depression, heart disease, hypertension, peptic ulcer disease, stroke, and cancer were compared between individuals in the identified biochemical clusters. The identified clusters were used to predict mortality and the inability to work (=number of sick days during the last 30 days) 10 years following the biomarker assessment. Results. Three distinct biochemical clusters were identified and validated. One of these clusters was characterized by average concentrations of all considered biomarkers (=reference cluster), one by average concentrations of CRP, IL-6, and fibrinogen but above-average levels of cortisol and creatinine (=metabo-endocrine cluster), and a third one characterized by above-average levels of CRP, IL-6, and fibrinogen, and average levels of cortisol and creatinine (=high-risk cluster). Compared to the other identified clusters, the high-risk cluster consisted of a significantly higher proportion of men vs. women, and individuals with a higher BMI, lower physical activity, and higher reported exposures to early-life stress. This cluster had the ...

وصف الملف: application/pdf

العلاقة: https://refubium.fu-berlin.de/handle/fub188/41496Test; http://dx.doi.org/10.17169/refubium-41218Test; urn:nbn:de:kobv:188-refubium-41496-9

الإتاحة: https://doi.org/10.17169/refubium-41218Test
https://refubium.fu-berlin.de/handle/fub188/41496Test
https://nbn-resolving.org/urn:nbn:de:kobv:188-refubium-41496-9Test

المؤلفون: Spaegele, Nina, Lewin, Tova, Talmon, Anat

المصدر: Psychological Trauma: Theory, Research, Practice, and Policy ; ISSN 1942-969X 1942-9681

الإتاحة: https://doi.org/10.1037/tra0001597Test
http://psycnet.apa.org/psycarticles/2024-14495-001.pdfTest