المؤلفون: Ortuño, Felipe, Moreno-Íñiguez, Miguel, Millán, Manuel, Soutullo, César A., Bonelli, Raphael M.

المصدر: Wiener Medizinische Wochenschrift ; volume 156, issue 5-6, page 179-184 ; ISSN 0043-5341 1563-258X

مصطلحات موضوعية: General Medicine

الإتاحة: https://doi.org/10.1007/s10354-005-0248-3Test

المؤلفون: Soutullo, César A, Chang, Kiki D, Díez‐Suárez, Azucena, Figueroa‐Quintana, Ana, Escamilla‐Canales, Inmaculada, Rapado‐Castro, Marta, Ortuño, Felipe

المصدر: Bipolar Disorders ; volume 7, issue 6, page 497-506 ; ISSN 1398-5647 1399-5618

الوصف: Objective: There is considerable skepticism outside the US over the prevalence of pediatric bipolar disorder (BD). We wished to evaluate the epidemiology of BD in children and adolescents in non‐US samples. Method: We reviewed studies on the prevalence of BD in children and adolescents in international samples. We also describe our sample of 27 children with BD at the University of Navarra. Results: There are important and frequently overlooked differences in the definition of BD between the International Classification of Diseases 10th edition (ICD‐10) and DSM‐IV and methodological differences in epidemiological studies that may partially explain international differences in prevalence of pediatric BD. The prevalence of bipolar spectrum disorder in young adults in Switzerland is 11%. In Holland the 6‐month prevalence of mania in adolescents was 1.9% and of hypomania 0.9%. Only 1.2% of hospitalized youth (<15 years) in Denmark and 1.7% of adolescents in Finland had BD. In our clinic, the prevalence of DSM‐IV BD in children 5–18 years old is 4%, and of any mood disorders 27%. There are also data from Brazil, India and Turkey with varying results. Conclusion: Relative lack of data, ICD‐10 and DSM‐IV differences in diagnostic criteria, different levels of recognition of Child and Adolescent Psychiatry as a true specialty in Europe, clinician bias against BD, an overdiagnosis of the disorder in USA and/or a true higher prevalence of pediatric BD in USA may explain these results. US–International differences may be a methodological artifact and research is needed in this field.

الإتاحة: https://doi.org/10.1111/j.1399-5618.2005.00262.xTest

المؤلفون: Romero, Soledad, DelBello, Melissa P, Soutullo, Cesar A, Stanford, Kevin, Strakowski, Stephen M

المصدر: Bipolar Disorders ; volume 7, issue 6, page 617-622 ; ISSN 1398-5647 1399-5618

الوصف: Objectives: To compare family environmental characteristics of families with at least one bipolar parent and families with parents without any Axis I disorder. Methods: Family environment of 24 families with at least one parent with bipolar disorder (BPD) and 27 families with healthy parents (healthy families, HF) were assessed using the Family Environment Scale (FES). We compared FES subscale scores between BPD and HF. We also compared FES normative scores with scores of BPD families. Results: Seventeen (71%) of the 24 BPD families had at least one child with a mood disorder and one (3.7%) of the 27 HF had a child with a mood disorder. Families with BPD reported lower cohesion (p = 0.009) and expressiveness (p = 0.03) scores compared with HF, after controlling for group socioeconomic status differences. Bilineal BPD families had higher cohesion scores than unilineal BPD families (p = 0.05). We found no significant differences in any subscales between BPD families with (n = 9) versus without (n = 15) children with BPD. Compared with normative FES data BPD families reported lower cohesion (C) (p = 0.02) and independence (IND) (p = 0.004) scores and higher conflict (CON) (p = 0.02), intellectual‐cultural orientation (ICO) (p = 0.05), moral‐religious emphasis (MRE) (p < 0.001) and control (CTL) (p < 0.001) scores. Conclusion: Our results suggest that members of BPD families may have difficulty communicating effectively with one another, suggesting that interventions aimed at improving this may be beneficial to patients with BPD. Results suggest that the impact of different lifestyles in different communities may influence FES scores, and thus it is important to use demographically matched comparison groups.

الإتاحة: https://doi.org/10.1111/j.1399-5618.2005.00270.xTest

المؤلفون: Cervera-enguix, Salvador, Soutullo, Cesar A., Landecho, Ignacio, Murillo-jelsbak, Ricardo

المصدر: International Journal of Psychiatry in Clinical Practice ; volume 7, issue 3, page 193-197 ; ISSN 1365-1501 1471-1788

الإتاحة: https://doi.org/10.1080/13651500310001446Test

المؤلفون: Gamazo-Garrán, Pilar, Soutullo, Cesar A., Ortuño, Felipe

المصدر: Journal of Child and Adolescent Psychopharmacology ; volume 12, issue 3, page 259-263 ; ISSN 1044-5463 1557-8992

مصطلحات موضوعية: Pharmacology (medical), Psychiatry and Mental health, Pediatrics, Perinatology and Child Health

الإتاحة: https://doi.org/10.1089/104454602760386950Test

المؤلفون: Soutullo, Cesar A, DelBello, Melissa P, Ochsner, Jennifer E, McElroy, Susan L, Taylor, Siobhan A, Strakowski, Stephen M, Keck, Paul E

المصدر: Journal of Affective Disorders ; volume 70, issue 3, page 323-327 ; ISSN 0165-0327

مصطلحات موضوعية: Psychiatry and Mental health, Clinical Psychology

الإتاحة: https://doi.org/10.1016/s0165-0327Test(01)00336-6
https://api.elsevier.com/content/article/PII:S0165032701003366?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0165032701003366?httpAccept=text/plainTest

المؤلفون: DelBello, Melissa P, Soutullo, Cesar A, Hendricks, Wendi, Niemeier, R Todd, McElroy, Susan L, Strakowski, Stephen M

المصدر: Bipolar Disorders ; volume 3, issue 2, page 53-57 ; ISSN 1398-5647 1399-5618

الوصف: Objectives: To compare demographic and clinical characteristics between bipolar adolescents with and without a history of stimulant treatment, we hypothesized that adolescents treated with stimulants would have an earlier age at onset of bipolar disorder, independent of co‐occurring attention‐deficit‐hyperactivity disorder (ADHD). Method: Thirty‐four adolescents hospitalized with mania were assessed using the Washington University at St Louis Kiddie Schedule for Affective Disorders and Schizophrenia (WASH‐U‐KSADS). We systematically evaluated age at onset of bipolar disorder and pharmacological treatment history. Results: Bipolar adolescents with a history of stimulant exposure prior to the onset of bipolar disorder had an earlier age at onset of bipolar disorder than those without prior stimulant exposure. Additionally, bipolar adolescents treated with at least two stimulant medications had a younger age at onset compared with those who were treated with one stimulant. There was no difference in age at onset of bipolar disorder between bipolar adolescents with and without ADHD. Conclusions: Our results suggest that stimulant treatment, independent of ADHD, is associated with younger age at onset of bipolar disorder. A behavioral sensitization model is proposed to explain our findings. There are several limitations to our study including the small sample size, the retrospective assessment of stimulant exposure and age at onset of bipolar disorder, and the inclusion of only hospitalized patients, who may be more likely to present with a severe illness. Nonetheless, future prospective longitudinal investigations that systematically assess the effects of stimulant medications in children with or at genetic risk for bipolar disorder are warranted.

الإتاحة: https://doi.org/10.1034/j.1399-5618.2001.030201.xTest

المؤلفون: Schlatter, F. Javier, Soutullo, Cesar A., Cervera-Enguix, Salvador

المصدر: Journal of Clinical Psychopharmacology ; volume 21, issue 4, page 464-466 ; ISSN 0271-0749

الإتاحة: https://doi.org/10.1097/00004714-200108000-00021Test
https://journals.lww.com/00004714-200108000-00021Test

المؤلفون: Delbello, Melissa P., Lopez-Larson, Melissa P., Soutullo, Cesar A., Strakowski, Stephen M.

المصدر: Journal of Child and Adolescent Psychopharmacology ; volume 11, issue 1, page 95-103 ; ISSN 1044-5463 1557-8992

الإتاحة: https://doi.org/10.1089/104454601750143528Test

المؤلفون: Nelson, Erik, Brusman, Lori, Holcomb, Jeff, Soutullo, Cesar, Beckman, Deanna, Welge, Jeffrey A., Kuppili, Naveen, McElroy, Susan L.

المصدر: Journal of Affective Disorders ; volume 64, issue 2-3, page 249-255 ; ISSN 0165-0327

مصطلحات موضوعية: Psychiatry and Mental health, Clinical Psychology

الإتاحة: https://doi.org/10.1016/s0165-0327Test(00)00255-x
https://api.elsevier.com/content/article/PII:S016503270000255X?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S016503270000255X?httpAccept=text/plainTest