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1دورية أكاديمية
المؤلفون: Stewart, Eva C. D., Bribiesca-Contreras, Guadalupe, Taboada, Sergi, Wiklund, Helena, Ravara, Ascensão, Pape, Ellen, De Smet, Bart, Neal, Lenka, Cunha, Marina R., Jones, Daniel O. B., Smith, Craig R., Glover, Adrian G., Dahlgren, Thomas G.
المصدر: Diversity and Distributions, 2023 Jun 01. 29(6), 727-747.
الوصول الحر: https://www.jstor.org/stable/48727338Test
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2دورية أكاديمية
المؤلفون: O’Brien, Kristin M, Crockett, Elizabeth L, Adams, Byron J, Amsler, Charles D, Appiah-Madson, Hannah J, Collins, Allen, Desvignes, Thomas, Detrich, H William, Distel, Daniel L, Eppley, Sarah M, Frable, Benjamin W, Franz, Nico M, Grim, Jeffrey M, Kocot, Kevin M, Mahon, Andrew R, Mayfield-Meyer, Teresa J, Mikucki, Jill A, Moser, William E, Schmull, Michaela, Seid, Charlotte A, Smith, Craig R, Todgham, Anne E, Watkins-Colwell, Gregory J
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 119(50)
مصطلحات موضوعية: Antarctic Regions
الوصول الحر: https://escholarship.org/uc/item/5bf6h4zhTest
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3دورية أكاديمية
المؤلفون: Shahim, Bahira, Redfors, Björn, Lindman, Brian R, Chen, Shmuel, Dahlen, Torsten, Nazif, Tamim, Kapadia, Samir, Gertz, Zachary M, Crowley, Aaron C, Li, Ditian, Thourani, Vinod H, Kodali, Susheel K, Zajarias, Alan, Babaliaros, Vasilis C, Guyton, Robert A, Elmariah, Sammy, Herrmann, Howard C, Cohen, David J, Mack, Michael J, Smith, Craig R, Leon, Martin B, George, Isaac
المصدر: Journal of the American Heart Association. 11(11)
مصطلحات موضوعية: Heart Disease, Clinical Research, Transplantation, Cardiovascular, Aortic Valve, Aortic Valve Stenosis, Heart Valve Prosthesis Implantation, Humans, Lymphocytes, Neutrophils, Registries, Risk Factors, Severity of Illness Index, Treatment Outcome, aortic stenosis, neutrophil-to-lymphocyte ratio, NLR, surgical aortic valve replacement, transcatheter aortic valve replacement, neutrophil‐to‐lymphocyte ratio, Cardiorespiratory Medicine and Haematology
الوصف: Background The neutrophil-to-lymphocyte ratio (NLR) as a marker of systemic inflammation has been associated with worse prognosis in several chronic disease states, including heart failure. However, few data exist on the prognostic impact of elevated baseline NLR or change in NLR levels during follow-up in patients undergoing transcatheter or surgical aortic valve replacement (TAVR or SAVR) for aortic stenosis. Methods and Results NLR was available in 5881 patients with severe aortic stenosis receiving TAVR or SAVR in PARTNER (Placement of Aortic Transcatheter Valves) I, II, and S3 trials/registries (median [Q1, Q3] NLR, 3.30 [2.40, 4.90]); mean NLR, 4.10; range, 0.5-24.9) and was evaluated as continuous variable and categorical tertiles (low: NLR ≤2.70, n=1963; intermediate: NLR 2.70-4.20, n=1958; high: NLR ≥4.20, n=1960). No patients had known baseline infection. High baseline NLR was associated with increased risk of death or rehospitalization at 3 years (58.4% versus 41.0%; adjusted hazard ratio [aHR], 1.39; 95% CI, 1.18-1.63; P
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/59d3w0cpTest
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4دورية أكاديمية
المؤلفون: Amon, Diva J, Gollner, Sabine, Morato, Telmo, Smith, Craig R, Chen, Chong, Christiansen, Sabine, Currie, Bronwen, Drazen, Jeffrey C, Fukushima, Tomohiko, Gianni, Matthew, Gjerde, Kristina M, Gooday, Andrew J, Grillo, Georgina Guillen, Haeckel, Matthias, Joyini, Thembile, Ju, Se-Jong, Levin, Lisa A, Metaxas, Anna, Mianowicz, Kamila, Molodtsova, Tina N, Narberhaus, Ingo, Orcutt, Beth N, Swaddling, Alison, Tuhumwire, Joshua, Palacio, Patricio Urueña, Walker, Michelle, Weaver, Phil, Xu, Xue-Wei, Mulalap, Clement Yow, Edwards, Peter ET, Pickens, Chris
مصطلحات موضوعية: Environmental Management, Environmental Sciences, Human Society, Policy and Administration, Political Science, Prevention, Life Below Water, Deep-sea mining, Hydrothermal vents, Cobalt-rich ferromanganese crusts, Polymetallic nodules, Seamounts, Polymetallic sulfides, Policy, International Seabed Authority, Environmental Science and Management, Law, Fisheries, Environmental management, Policy and administration, Political science
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/0w48f05qTest
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5دورية أكاديمية
المؤلفون: Amon, Diva J, Levin, Lisa A, Metaxas, Anna, Mudd, Gavin M, Smith, Craig R
المصدر: One Earth. 5(3)
مصطلحات موضوعية: Affordable and Clean Energy
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/3sz1d3qxTest
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6دورية أكاديمية
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7دورية أكاديمية
المؤلفون: Levin, Lisa A, Bett, Brian J, Gates, Andrew R, Heimbach, Patrick, Howe, Bruce M, Janssen, Felix, McCurdy, Andrea, Ruhl, Henry A, Snelgrove, Paul, Stocks, Karen I, Bailey, David, Baumann-Pickering, Simone, Beaverson, Chris, Benfield, Mark C, Booth, David J, Carreiro-Silva, Marina, Colaco, Ana, Eble, Marie C, Fowler, Ashley M, Gjerde, Kristina M, Jones, Daniel OB, Katsumata, K, Kelley, Deborah, Le Bris, Nadine, Leonardi, Alan P, Lejzerowicz, Franck, Macreadie, Peter I, McLean, Dianne, Meitz, Fred, Morato, Telmo, Netburn, Amanda, Pawlowski, Jan, Smith, Craig R, Sun, Song, Uchida, Hiroshi, Vardaro, Michael F, Venkatesan, R, Weller, Robert A
مصطلحات موضوعية: deep sea, ocean observation, blue economy, essential ocean variables, biodiversity, ocean sensors, Oceanography, Ecology
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/4wx0d9b8Test
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8دورية أكاديمية
المؤلفون: Stewart, Eva C.D., Bribiesca-Contreras, Guadalupe, Taboada, Sergi, Wiklund, Helena, Ravara, Ascensaõ, Pape, Ellen, De Smet, Bart, Neal, Lenka, Cunha, M.R., Jones, Daniel O.B., Smith, Craig R., Glover, A.G., Dahlgren, Thomas G.
الوصف: Aim: the abyssal Clarion-Clipperton Zone (CCZ), Pacific Ocean, is an area of commercial importance owing to the growing interest in mining high-grade polymetallic nodules at the seafloor for battery metals. Research into the spatial patterns of faunal diversity, composition, and population connectivity is needed to better understand the ecological impacts of potential resource extraction. Here, a DNA taxonomy approach is used to investigate regional-scale patterns of taxonomic and phylogenetic alpha and beta diversity, and genetic connectivity, of the dominant macrofaunal group (annelids) across a 6 million km2 region of the abyssal seafloor. Location: the abyssal seafloor (3932–5055 m depth) of the Clarion-Clipperton Zone, equatorial Pacific Ocean. Methods: we used a combination of new and published barcode data to study 1866 polychaete specimens using molecular species delimitation. Both phylogenetic and taxonomic alpha and beta diversity metrics were used to analyse spatial patterns of biodiversity. Connectivity analyses were based on haplotype distributions for a subset of the studied taxa. Results: DNA taxonomy identified 291–314 polychaete species from the COI and 16S datasets respectively. Taxonomic and phylogenetic beta diversity between sites were relatively high and mostly explained by lineage turnover. Over half of pairwise comparisons were more phylogenetically distinct than expected based on their taxonomic diversity. Connectivity analyses in abundant, broadly distributed taxa suggest an absence of genetic structuring driven by geographical location. Main conclusions: species diversity in abyssal Pacific polychaetes is high relative to other deep-sea regions. Results suggest that environmental filtering, where the environment selects against certain species, may play a significant role in regulating spatial patterns of biodiversity in the CCZ. A core group of widespread species have diverse haplotypes but are well connected over broad distances. Our data suggest that the high environmental and ...
وصف الملف: text
العلاقة: https://eprints.soton.ac.uk/481647/1/Diversity_and_Distributions_2023_Stewart.pdfTest; Stewart, Eva C.D., Bribiesca-Contreras, Guadalupe, Taboada, Sergi, Wiklund, Helena, Ravara, Ascensaõ, Pape, Ellen, De Smet, Bart, Neal, Lenka, Cunha, M.R., Jones, Daniel O.B., Smith, Craig R., Glover, A.G. and Dahlgren, Thomas G. (2023) Biodiversity, biogeography, and connectivity of polychaetes in the world's largest marine minerals exploration frontier. Diversity and Distributions, 29 (6), 727-747. (doi:10.1111/ddi.13690 ).
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9دورية أكاديمية
المؤلفون: Simon-Lledó, Erik, Amon, Diva J., Bribiesca‐Contreras, Guadalupe, Cuvelier, Daphne, Durden, Jennifer M., Ramalho, Sofia P., Uhlenkott, Katja, Arbizu, Pedro Martinez, Benoist, Noëlie, Copley, Jonathan, Dahlgren, Thomas G., Glover, Adrian G., Fleming, Bethany, Horton, Tammy, Ju, Se Jong, Mejía-Saenz, Alejandra, McQuaid, Kirsty, Pape, Ellen, Park, Chailinn, Smith, Craig R., Jones, Daniel O.B.
الوصف: Abyssal seafloor communities cover more than 60% of Earth’s surface. Despite their great size, abyssal plains extend across modest environmental gradients compared to other marine ecosystems. However, little is known about the patterns and processes regulating biodiversity or potentially delimiting biogeographical boundaries at regional scales in the abyss. Improved macroecological understanding of remote abyssal environments is urgent as threats of widespread anthropogenic disturbance grow in the deep ocean. Here, we use a new, basin-scale dataset to show the existence of clear regional zonation in abyssal communities across the 5,000 km span of the Clarion–Clipperton Zone (northeast Pacific), an area targeted for deep-sea mining. We found two pronounced biogeographic provinces, deep and shallow-abyssal, separated by a transition zone between 4,300 and 4,800 m depth. Surprisingly, species richness was maintained across this boundary by phylum-level taxonomic replacements. These regional transitions are probably related to calcium carbonate saturation boundaries as taxa dependent on calcium carbonate structures, such as shelled molluscs, appear restricted to the shallower province. Our results suggest geochemical and climatic forcing on distributions of abyssal populations over large spatial scales and provide a potential paradigm for deep-sea macroecology, opening a new basis for regional-scale biodiversity research and conservation strategies in Earth’s largest biome.
وصف الملف: text
العلاقة: https://eprints.soton.ac.uk/480577/1/s41559_023_02122_9.pdfTest; Simon-Lledó, Erik, Amon, Diva J., Bribiesca‐Contreras, Guadalupe, Cuvelier, Daphne, Durden, Jennifer M., Ramalho, Sofia P., Uhlenkott, Katja, Arbizu, Pedro Martinez, Benoist, Noëlie, Copley, Jonathan, Dahlgren, Thomas G., Glover, Adrian G., Fleming, Bethany, Horton, Tammy, Ju, Se Jong, Mejía-Saenz, Alejandra, McQuaid, Kirsty, Pape, Ellen, Park, Chailinn, Smith, Craig R. and Jones, Daniel O.B. (2023) Carbonate compensation depth drives abyssal biogeography in the northeast Pacific. Nature Ecology and Evolution, 7 (9), 1388-1397. (doi:10.1038/s41559-023-02122-9 ).
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10دورية أكاديمية
المؤلفون: Galper, Benjamin Z., Chinnakondepalli, Khaja M., Wang, Kaijun, Magnuson, Elizabeth A., Lu, Michael, Thourani, Vinod H., Kodali, Susheel, Makkar, Raj, Herrmann, Howard C., Kapadia, Samir, Williams, Mathew, Webb, John, Smith, Craig R., Mack, Michael J., Leon, Martin B., Cohen, David J.
المساهمون: Edwards Lifesciences
المصدر: Circulation ; volume 147, issue 21, page 1594-1605 ; ISSN 0009-7322 1524-4539
الوصف: Background: In patients with severe symptomatic aortic stenosis at low surgical risk, transfemoral transcatheter aortic valve replacement (TAVR) with the SAPIEN 3 valve has been shown to reduce the composite of death, stroke, or rehospitalization at 2-year follow-up compared with surgical aortic valve replacement (SAVR). Whether TAVR is cost-effective compared with SAVR for low-risk patients remains uncertain. Methods: Between 2016 and 2017, 1000 low-risk patients with aortic stenosis were randomly assigned to TAVR with the SAPIEN 3 valve or SAVR in the PARTNER 3 trial (Placement of Aortic Transcatheter Valves). Of these patients, 929 underwent valve replacement, were enrolled in the United States, and were included in the economic substudy. Procedural costs were estimated using measured resource use. Other costs were determined by linkage with Medicare claims or by regression models when linkage was not feasible. Health utilities were estimated using the EuroQOL 5-item questionnaire. With the use of a Markov model informed by in-trial data, lifetime cost-effectiveness from the perspective of the US health care system was estimated in terms of cost per quality-adjusted life-year gained. Results: Although procedural costs were nearly $19 000 higher with TAVR, total index hospitalization costs were only $591 more with TAVR compared with SAVR. Follow-up costs were lower with TAVR such that TAVR led to 2-year cost savings of $2030/patient compared with SAVR (95% CI, –$6222 to $1816) and a gain of 0.05 quality-adjusted life-years (95% CI, –0.003 to 0.102). In our base-case analysis, TAVR was projected to be an economically dominant strategy with a 95% probability that the incremental cost-effectiveness ratio for TAVR would be <$50 000/quality-adjusted life-year gained (consistent with high economic value from a US health care perspective). These findings were sensitive to differences in long-term survival, however, such that a modest long-term survival advantage with SAVR would render SAVR cost-effective (although ...
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