المؤلفون: Aleksander Stupnicki, Basil Suresh, Saurabh Jain

المصدر: Interactive Journal of Medical Research, Vol 13, p e50698 (2024)

مصطلحات موضوعية: Computer applications to medicine. Medical informatics, R858-859.7, Medical technology, R855-855.5

الوصف: BackgroundQuality and accuracy of online scientific data are crucial, given that the internet and social media serve nowadays as primary sources of medical knowledge. ObjectiveThis study aims to analyze the relationship between scientific relevance and online visibility of strabismus research to answer the following questions: (1) Are the most popular strabismus papers scientifically relevant? (2) Are the most high-impact strabismus studies shared enough online? MethodsThe Altmetric Attention Score (AAS) was used as a proxy for online visibility, whereas citations and the journal’s impact factor (IF) served as a metric for scientific relevance. Using “strabismus” as a keyword, 100 papers with the highest AAS and 100 papers with the highest number of citations were identified. Statistical analyses, including the Spearman rank test, linear regression, and factor analysis, were performed to assess the relationship between AAS, citations, a journal’s IF, and mentions across 18 individual Web 2.0 platforms. ResultsA weak, positive, statistically significant correlation was observed between normalized AAS and normalized citations (P

وصف الملف: electronic resource

العلاقة: https://www.i-jmr.org/2024/1/e50698Test; https://doaj.org/toc/1929-073XTest

الوصول الحر: https://doaj.org/article/6cc75d86c6c142ed866eda1cd1bfc99bTest

المؤلفون: Gaurav Kumar Jha, Rajesh Ashok Kshirsagar, Vikram Singh, Sudhir Ramlal Pawar, Vivek Nair, Daksh Manish Kedia, Ojas Desai, Saurabh Jain

المصدر: Journal of Clinical and Diagnostic Research, Vol 17, Iss 8, Pp 21-26 (2023)

مصطلحات موضوعية: non-steroidal anti-inflammatory drugs, postoperative sequalae, wisdom tooth surgery, Medicine

الوصف: Introduction: The surgical removal of mandibular third molars is generally followed by complaints of pain, trismus, and swelling. The duration of surgery and the reflection of a mucoperiosteal flap have been shown to affect the intensity and frequency of postoperative complaints. Pain from third molar surgery typically begins within one to three hours after surgery and ranges in intensity from moderate to severe. Numerous analgesics have been used to minimise pain and discomfort following the surgical removal of impacted third molars. Commonly used agents include ibuprofen, diclofenac sodium, paracetamol, or their combinations. Newer drugs, such as selective COX inhibitors, have not been extensively used for minor oral surgical procedures. Aim: To compare the clinical efficacy of celecoxib and diclofenac sodium on pain, swelling, and mouth opening after the surgical removal of impacted mandibular third molars. Materials and Methods: A split-mouth randomised controlled clinical trial was conducted in the Department of Oral and Maxillofacial Surgery at BharatiVidyapeeth DU Dental College and Hospital, Pune, Maharashtra, India. The study duration was six months, from August 2022 to January 2023. A total of 21 subjects (11 males and 10 females) who required surgical extraction of an impacted mandibular third molar were selected. All subjects were randomly allocated to receive one of the following treatments twice a day for five days after surgery: celecoxib 200 mg (n=11) or diclofenac sodium 75 mg (n=10). Pain scores were evaluated using the Visual Analogue Scale (VAS) on postoperative day one, two, and three. Swelling and mouth opening were evaluated on Postoperative Day (POD) two and seven. Intergroup comparison was done using Student’s t-test. Results: The mean age of the study participants was 28±1.5 years, and the mean VAS score for pain evaluation with celecoxib was 6.61, 5.38, and 5.00 on day 1 (p=0.027), 2 (p=0.972), and 3 (p=0.809), respectively. The difference in swelling values for the celecoxib group was significant, while there were no significant differences in the values of mouth opening. Conclusion: It was concluded that celecoxib 200 mg is a better analgesic and anti-inflammatory compared to diclofenac sodium 75 mg. Celecoxib was easily tolerable and comfortable for the patients. There was no significant difference in the values of mouth opening.

وصف الملف: electronic resource

العلاقة: https://jcdr.net/articles/PDF/18307/63808_CETest[Ra1]_F(IS)_PF1(HB_KM_OM)_QC(SHK_SS)_PFA_NC(KM)_PN(KM).pdf; https://doaj.org/toc/2249-782XTest; https://doaj.org/toc/0973-709XTest

الوصول الحر: https://doaj.org/article/69d6fc0bae9c44e886de52e8fe4e2dc2Test

المؤلفون: Anand Ballabh Joshi, Megha Raj Banjara, Sachi Chuke, Axel Kroeger, Saurabh Jain, Abraham Aseffa, John C Reeder

المصدر: PLoS Neglected Tropical Diseases, Vol 17, Iss 11, p e0011714 (2023)

مصطلحات موضوعية: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

الوصف: Nepal, Bangladesh, and India signed a Memorandum of Understanding (MoU) in 2005 to eliminate visceral leishmaniasis (VL) as a public health problem from the Indian subcontinent by 2015. By 2021, the number of reported VL cases in these countries had declined by over 95% compared to 2007. This dramatic success was achieved through an elimination programme that implemented early case detection and effective treatment, vector control, disease surveillance, community participation, and operational research that underpinned these strategies. The experience offered an opportunity to assess the contribution of implementation research (IR) to VL elimination in Nepal. Desk review and a stakeholder workshop was conducted to analyse the relationship between key research outputs, major strategic decisions in the national VL elimination programme, and annual number of reported new cases over time between 2005 and 2023. The results indicated that the key decisions across the strategic elements, throughout the course of the elimination programme (such as on the most appropriate tools for diganostics and treatment, and on best strategies for case finding and vector management), were IR informed. IR itself responded dynamically to changes that resulted from interventions, addressing new questions that emerged from the field. Close collaboration between researchers, programme managers, and implementers in priority setting, design, conduct, and review of studies facilitated uptake of evidence into policy and programmatic activities. VL case numbers in Nepal are now reduced by 90% compared to 2005. Although direct attribution of disease decline to research outputs is difficult to establish, the Nepal experience demonstrates that IR can be a critical enabler for disease elimination. The lessons can potentially inform IR strategies in other countries with diseases targeted for elimination.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1935-2727Test; https://doaj.org/toc/1935-2735Test

الوصول الحر: https://doaj.org/article/7d18c0ab66284e7290aebcd3d9e5e8c6Test

المؤلفون: Saurabh Jain, Satish Rohra, Harshwardhan Dawar, Bhupendra Kushwah, Adit Agrawal

المصدر: Chinese Journal of Traumatology, Vol 26, Iss 4, Pp 223-227 (2023)

مصطلحات موضوعية: Intertrochanteric fracture, Lateral trochanteric wall, Intramedullary nail, Proximal femoral nail, Trochanteric buttress plate, Medicine (General), R5-920

الوصف: Purpose: Intramedullary implants are well accepted fixation of all types of intertrochanteric (IT) fractures, both stable and unstable types. Intramedullary nails have an ability to effectively support the posteromedial part, but fail to buttress the broken lateral wall requiring lateral augmentation. The aim of this study was to evaluate the outcome of proximal femoral nail augmented with trochanteric buttress plate for broken lateral wall with IT fractures, which was fixed to the femur through hip screw and anti-rotation screw nail. Methods: Of 30 patients, 20 had Jensen-Evan type III and 10 had type V fractures. Patients with IT fracture of broken lateral wall and aged more than 18 years, in whom satisfactory reduction was achieved by closed methods, were included in the study. Patients with pathologic or open fractures, polytrauma, prior hip surgery, non-ambulatory prior to surgery, and those who refused to participate were excluded. The operative time, blood loss, radiation exposure, quality of reduction, functional outcome, and union time were evaluated. All data were coded and recorded in Microsoft Excel spread sheet program. SPSS 20.0 was used for data analysis and normality of the continuous data was checked using Kolmogorv Smirnov test. Results: The mean age of patients in the study was 60.3 years. The mean duration of surgery (min), mean intra-operative blood loss (mL) and mean number of exposures were 91.86 ± 12.8 (range 70 – 122), 144.8 ± 3.6 (range 116 – 208), and 56.6 (range 38 – 112), respectively. The mean union time was 11.6 weeks and the mean Harris hip score was 94.1. Conclusion: Lateral trochanteric wall in IT fractures is significantly important, and needs to be reconstructed adequately. Nail-plate construct of trochanteric buttress plate fixed with hip screw and anti-rotation screw of proximal femoral nail can be successfully used to augment, fix or buttress the lateral trochanteric wall giving excellent to good results of early union and reduction.

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S1008127523000214Test; https://doaj.org/toc/1008-1275Test

الوصول الحر: https://doaj.org/article/4f617d202bd94c65a389b4222a1e1596Test

المؤلفون: Sunil Rajan, Saurabh Jain, Chetan Singh Dhosariya, Ashish Goyal

المصدر: Journal of Orthopedics, Traumatology and Rehabilitation, Vol 15, Iss 1, Pp 68-72 (2023)

مصطلحات موضوعية: bilateral total knee arthroplasty, day-care total knee arthroplasty, outpatient, Orthopedic surgery, RD701-811

الوصف: Introduction: Outpatient total knee arthroplasty (TKA) in selected patients has proved to be beneficial to both patients and health-care systems in terms of safety, reoperations, readmission rate, complications, cost-effectiveness, increased patient satisfaction, and improved outcome scores. However, these benefits of outpatient TKA have been limited to unilateral TKA. Hence, we reviewed the results of bilateral outpatient TKA in five patients to educate surgeons about the feasibility, safety, benefit, and area of research for bilateral outpatient TKA and its worth consideration in selected groups of patients to decrease patient morbidity and cost. Materials and Methods: Five bilateral knee arthroplasties done as outpatient surgeries at our center were reviewed for patient satisfaction, readmission, reoperation, emergency visit without readmission, unplanned clinic visits, and complications. All these cases followed proper selection criteria, adequate preoperative planning, and strict adherence to our standard operating protocols. Results: Five patients of bilateral outpatient TKA with a mean age of 48.6 years were included in the study. All patients have excellent outcomes at 1-month follow-up. The mean Knee Society Score was 91. None of the patients required reoperation or revision surgery. All the patients demonstrated a high level of satisfaction, without any complications of instability, infection, ileus, urinary tract infection, or deep vein thrombosis. Conclusion: Bilateral outpatient TKA can be considered a suitable alternative with benefits of reduced hospital stay, and hence decreased morbidity and cost, early mobilization and recovery, economical advantages, minimal pain owing to multimodal analgesia, faster return to normalcy, and less mental stress or disturbances, but in selected patients at specialized center only. The study stresses on the fact of bilateral outpatient TKA should also considered a key area of research in the field of outpatient TKA in addition to other areas of universal selection criteria, ideal risk assessment tool, safety aspect, surgical duration, ambulation, and reasons for not able to discharge.

وصف الملف: electronic resource

العلاقة: http://www.jotr.in/article.asp?issn=0975-7341;year=2023;volume=15;issue=1;spage=68;epage=72;aulast=RajanTest; https://doaj.org/toc/0975-7341Test

الوصول الحر: https://doaj.org/article/194a40dc61cb4c7c9bc6cbb4e1d08b67Test

المؤلفون: Mrinal Pahwa, Mahendra Singh, Vipin Tyagi, Manu Gupta, Saurabh Jain, Sudhir Chaddha, Harsha Jauhari

المصدر: Indian Journal of Urology, Vol 39, Iss 1, Pp 46-52 (2023)

مصطلحات موضوعية: Diseases of the genitourinary system. Urology, RC870-923

الوصف: Introduction: Continuous ambulatory peritoneal dialysis (CAPD) catheter placement is a part of renal replacement therapy. We describe our 20-year experience in using the open technique and assess its safety, efficacy, and outcome in the treatment of end-stage renal disease patients. Methods: In a retrospective study, we analyzed data of all patients who had a CAPD catheter placed using our open dissection technique using local anesthesia over the previous 20 years, with minimum 1 year of follow-up. Intraoperative data, postoperative data, and complications were noted. Results: A total of 1410 cases were included in the study. The mean duration of follow-up was 72 ± 18 months (range 12–120 months). The mean operative time was 19 ± 7.5 min and mean hospital stay was 3 ± 1 days. No major intraoperative complications were noted. We observed a peritonitis rate of 0.49 episodes/patient/year. The most common reason for permanent catheter removal was refractory peritonitis in 21%, followed by flow failure in 7%, and ultrafiltration failure in 6.5%. The death-censored technical survival rate was 94.3%, 83.2%, 75.9%, 69.2%, and 60.6% patients at 1 year, 2 years, 3 years, 4 years, and 5 years, respectively. Conclusions: The open dissection method of peritoneal dialysis catheter insertion using local anesthesia at well-experienced center is a simple, painless, and uncomplicated procedure with excellent outcomes. Optimal exposure, judicious use of energy source, and using appropriate technique provide good technical success rate with lesser complications.

وصف الملف: electronic resource

العلاقة: http://www.indianjurol.com/article.asp?issn=0970-1591;year=2023;volume=39;issue=1;spage=46;epage=52;aulast=PahwaTest; https://doaj.org/toc/0970-1591Test; https://doaj.org/toc/1998-3824Test

الوصول الحر: https://doaj.org/article/3911b8a393b9482fa533d9d0f4145e49Test

المؤلفون: Saurabh Jain, Mohammed E. Sayed, Wael I. Ibraheem, Abrar A. Ageeli, Sumir Gandhi, Hossam F. Jokhadar, Saad Saleh AlResayes, Hatem Alqarni, Abdullah Hasan Alshehri, Halah Mohammed Huthan, Atheer Alami, Mohammed Hussain Dafer Al Wadei, Yahya Aljabri

المصدر: Medicina, Vol 60, Iss 1, p 11 (2023)

مصطلحات موضوعية: dental implants, accuracy, computer-assisted implant surgery, robot-assisted implant surgery, navigation systems, surgical robot, Medicine (General), R5-920

الوصف: Background and Objectives: The present systematic review and meta-analysis undertake a comparison of studies that examine the accuracy of robot-assisted dental implant placement in relation to static computer-assisted implant surgery (SCAIS), dynamic computer-assisted implant surgery (DCAIS), and freehand procedures. This study aims to provide a comprehensive understanding of the precision of robot-assisted dental implant placement and its comparative efficacy in relation to other placement techniques. Methods: The guidelines recommended by Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) were used to organize and compose this review. Four electronic databases (PubMed, Web of Science, Scopus, and Cochrane) were systematically searched for pertinent articles. Articles were selected following the inclusion and exclusion criteria. Qualitative and quantitative analyses of the selected articles were performed. Results: The initial electronic search resulted in 1087 hits. Based on the inclusion and exclusion criteria, five articles were selected for qualitative analysis, out of which three were considered for quantitative analysis. Three parameters were considered for accuracy evaluation (angular, coronal, and apical deviation). The mean angular deviation was −1.22 degrees (95% CI, −1.06–−1.39), the mean coronal deviation was −0.15 mm (95% CI, −0.24–−0.07), and the mean apical deviation was −0.19 mm (95% CI, −0.27–−0.10). Conclusions: The robotic implant system was found to have significantly lower angular deviations and insignificantly lower coronal and apical deviations compared to DCAIS. Within the limitations of this review, it can be concluded that robot-assisted implant placement in resin models permits higher accuracy compared to DCAIS and SCAIS systems. However, due to the limited number of comparative studies with high heterogeneity, the findings of this review should be interpreted with caution. Further research is necessary to confirm the clinical application of robotics in implant surgery.

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/1648-9144/60/1/11Test; https://doaj.org/toc/1010-660XTest; https://doaj.org/toc/1648-9144Test

الوصول الحر: https://doaj.org/article/fd96cca0d3ae4457968a5b9c01f6e566Test

المؤلفون: Jorge Alvar, Saurabh Jain, Maria Teresa Beca-Martínez, Daniel Argaw, Jens Aagaard-Hansen

المصدر: BMJ Global Health, Vol 8, Iss 6 (2023)

مصطلحات موضوعية: Medicine (General), R5-920, Infectious and parasitic diseases, RC109-216

الوصف: Visceral leishmaniasis is a vector-borne, protozoan disease with severe public health implications. Following the successful implementation of an elimination programme in South Asia, there is now a concerted endeavour to replicate these efforts in Eastern Africa based on the five essential elimination pillars of case management, integrated vector management, effective surveillance, social mobilisation and operational research. This article highlights how key social determinants (SD) of health (poverty, sociocultural factors and gender, housing and clustering, migration and the healthcare system) operate at five different levels (socioeconomic context and position, differential exposure, differential vulnerability, differential outcomes and differential consequences). These SD should be considered within the context of increasing the success of the five-pillar elimination programme and reducing inequity in health.

وصف الملف: electronic resource

العلاقة: https://gh.bmj.com/content/8/6/e012638.fullTest; https://doaj.org/toc/2059-7908Test

الوصول الحر: https://doaj.org/article/4e3b9b8bb3dc4b0a9f55302693ec2a26Test

المؤلفون: Joanne Khabsa, Saurabh Jain, Amena El-Harakeh, Cynthia Rizkallah, Dhruv K Pandey, Nigus Manaye, Gladys Honein-AbouHaidar, Christine Halleux, Daniel Argaw Dagne, Elie A Akl

المصدر: PLoS Neglected Tropical Diseases, Vol 16, Iss 8, p e0010624 (2022)

مصطلحات موضوعية: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

الوصف: BackgroundIn visceral leishmaniasis (VL) patients coinfected with human immunodeficiency virus (HIV), combination therapy (liposomal amphotericin B infusion and oral miltefosine) is being considered as an alternative to liposomal amphotericin B monotherapy. We aimed to assess the views of stakeholders in relation to these treatment options.MethodologyIn a mixed methods study, we surveyed and interviewed patients, government functionaries, programme managers, health service providers, nongovernmental organizations, researchers, and World Health Organization (WHO) personnel. We used the Evidence to Decision (EtD) framework for data collection planning and analysis. Constructs of interest included valuation of outcomes, impact on equity, feasibility and acceptability of the treatment options, implementation considerations, monitoring and evaluation, and research priorities.Principal findings/conclusionMortality and non-serious adverse events were rated as "critical" by respectively the highest (61%) and lowest percentages (47%) of survey participants. Participants viewed clinical cure as essential for patients to regain productivity. Non-patient stakeholders emphasized the importance of "sustained" clinical cure. For most survey participants, combination therapy, compared with monotherapy, would increase health equity (40%), and be more acceptable (79%) and feasible (57%). Interviews revealed that combination therapy was more feasible and acceptable than monotherapy when associated with a shorter duration of hospitalization. The findings of the interviews provided insight into those of the survey. When choosing between alternative options, providers should consider the outcomes that matter to patients as well as the impact on equity, feasibility, and acceptability of the options.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1935-2727Test; https://doaj.org/toc/1935-2735Test

الوصول الحر: https://doaj.org/article/ecc60649b79849389e3742ec17b40273Test

المؤلفون: Maryam H. Mugri, Saurabh Jain, Mohammed E. Sayed, Amjad Hussain Asiri Halawi, Safa Ahmed Ibrahim Hamzi, Raniya Abdulaziz Saad Aljohani, Zainab Mousa Ali Madkhali, Asaad Khalid, Hossam F. Jokhadar, Mai Almarzouki, Ghaida A. Alhumaidan, Ahid Amer Alshahrani, Saeed M. Alqahtani, Nasser M. Alqahtani, Honey Lunkad

المصدر: Biomedicines, Vol 11, Iss 2, p 491 (2023)

مصطلحات موضوعية: 3D printing, heat polymerization, CAD/CAM, milling, tabbaq, khaini, Biology (General), QH301-705.5

الوصف: Tobacco consumption in its different forms can affect the optical and surface properties of dental materials that are used in the oral cavity. Thus, the present study was conducted to evaluate the effects of two commercially available smokeless tobacco products on the color stability and surface roughness of denture base resins that were fabricated using three different techniques (CAD/CAM milling, 3D printing, and conventional heat polymerization). A total of 126 denture base resin specimens were fabricated using the three different manufacturing techniques (n = 42 each). Specimens from each group were further subdivided into three subgroups (n = 14 each) and immersed in three different immersion media (a khaini suspension, a tabbaq suspension, and artificial saliva). The differences in color and surface roughness were assessed according to data that were collected and statistically analyzed using SPSS version 24.0. The tabbaq smokeless tobacco was found to cause greatest changes in color and surface roughness; the effect was observed to be highest in the 3D-printed specimens followed by the conventional heat-polymerized and CAD/CAM milled specimens. The mean changes in color and surface roughness were the highest for the tabbaq smokeless tobacco followed by the khaini smokeless tobacco and the artificial saliva. Statistically significant (p-value < 0.05) differences were observed among all techniques and suspensions. We concluded that the mean changes in color and surface roughness were significantly higher for the 3D-printed dentures compared to the conventional heat-polymerized and CAD/CAM-milled dentures. Thus, the results of the present study strengthened the concept that tobacco in any form can lead to changes in the color and surface roughness of denture base materials.

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/2227-9059/11/2/491Test; https://doaj.org/toc/2227-9059Test

الوصول الحر: https://doaj.org/article/edf13964efbd412db7df08a02482a1b9Test