المؤلفون: Hemetsberger Rayyan, Mankerious Nader, Muntané-Carol Guillem, Temporal Justin, Sulimov Dmitriy, Gaede Luise, Woitek Felix, Fadeuilhe Grau Edgar, Scalamogna Maria, Olschewski Maximilian, Mitsis Andreas, Ruzsa Zoltán, Toth Gabor G, Heyer Hajo, Toelg Ralph, Gómez-Hospital Joan A, Mügge Andreas, Hengstenberg Christian, Mangner Norman, Gori Tommaso, Cassese Salvatore, Carrillo Suárez Xavier, Abdel-Wahab Mohamed, Johnson Thomas, Richardt Gert, Allali Abdelhakim

مصطلحات موضوعية: 03.02. Klinikai orvostan

الوصف: Although the use of rotational atherectomy (RA) is off-label in the setting of ST-elevation myocardial infarction (STEMI), it can be the only option in severely calcified culprit lesions to achieve procedural success. We sought to investigate the safety and feasibility of RA during primary percutaneous coronary intervention (PPCI).This was a retrospective observational study of patients who underwent RA during PPCI from 12 European centers. The main outcomes were procedural success (defined as successful stent implantation with final TIMI flow 3 and residual stenosis <30%) and in-hospital mortality. A comparison of patients presenting with and without shock was performed.In 104 patients with RA during STEMI the mean age was 72.8±9.1 years, 35% presented with cardiogenic shock. Bailout RA was performed in 76.9% of cases. Mean burr size was 1.42±0.21mm. Procedural success was achieved in 86.5% of cases, with no difference between shocked and non-shocked patients (94.4% vs. 82.4%, p=0.13). In-hospital stent thrombosis occurred in 0.96%, perforation in 1.9% and burr entrapment in 2.9% of cases. In-spite of equally high procedural success, in-hospital mortality was higher in shocked (50%) compared with non-shocked patients (1.5%, p<0.0001).Patients presenting with STEMI, requiring RA, represent a high-risk population, frequently presenting with cardiogenic shock. In this analysis of selected patients, RA was performed as a bailout strategy in the majority, and as such RA seems to be feasible with a high procedural success rate. In the absence of cardiogenic shock, RA-facilitated PCI seems to be associated with low in-hospital mortality.

وصف الملف: text

العلاقة: http://publicatio.bibl.u-szeged.hu/30463/1/Hemetsberger.pdfTest; Hemetsberger Rayyan; Mankerious Nader; Muntané-Carol Guillem; Temporal Justin; Sulimov Dmitriy; Gaede Luise; Woitek Felix; Fadeuilhe Grau Edgar; Scalamogna Maria; Olschewski Maximilian; Mitsis Andreas; Ruzsa Zoltán; Toth Gabor G; Heyer Hajo; Toelg Ralph; Gómez-Hospital Joan A; Mügge Andreas; Hengstenberg Christian; Mangner Norman; Gori Tommaso; Cassese Salvatore; Carrillo Suárez Xavier; Abdel-Wahab Mohamed; Johnson Thomas; Richardt Gert; Allali Abdelhakim: In-hospital Outcomes of Rotational Atherectomy in ST-Elevation Myocardial Infarction: Results From the Multicentre ROTA-STEMI Network. CANADIAN JOURNAL OF CARDIOLOGY. ISSN 0828-282X (2024)

الإتاحة: https://doi.org/10.1016/j.cjca.2023.12.018Test
http://publicatio.bibl.u-szeged.hu/30463Test/
http://publicatio.bibl.u-szeged.hu/30463/1/Hemetsberger.pdfTest

المؤلفون: Kanoun Schnur Sadeek S., Pranevičius Robertas, Stark Cosima, Prunea Dan, Andréka Judit, Schmidt Albrecht, Harb Stefan, Ruzsa Zoltán, Zweiker Robert, Kane Jesse, Toth Gabor G.

مصطلحات موضوعية: 03.02. Klinikai orvostan

وصف الملف: text

العلاقة: http://publicatio.bibl.u-szeged.hu/29724/1/Kanoun.pdfTest; Kanoun Schnur Sadeek S.; Pranevičius Robertas; Stark Cosima; Prunea Dan; Andréka Judit; Schmidt Albrecht; Harb Stefan; Ruzsa Zoltán; Zweiker Robert; Kane Jesse; Toth Gabor G.: Operator decision-making in angiography-only guided revascularization for lesions not indicated for FFR: a QFR-based functional assessment in chronic coronary syndrome. FRONTIERS IN CARDIOVASCULAR MEDICINE, 11. ISSN 2297-055X (2024)

الإتاحة: https://doi.org/10.3389/fcvm.2024.1336341Test
http://publicatio.bibl.u-szeged.hu/29724Test/
http://publicatio.bibl.u-szeged.hu/29724/1/Kanoun.pdfTest

المؤلفون: Nemes Attila, Kormányos Árpád, Ruzsa Zoltán, Achim Alexandru, Ambrus Nóra, Lengyel Csaba Attila

مصطلحات موضوعية: 03.02. Klinikai orvostan

وصف الملف: text

العلاقة: http://publicatio.bibl.u-szeged.hu/29492/1/Nemes.pdfTest; Nemes Attila; Kormányos Árpád; Ruzsa Zoltán; Achim Alexandru; Ambrus Nóra; Lengyel Csaba Attila: Right Ventricular Longitudinal Shortening is not Associated with Left Ventricular Rotational Mechanics in Healthy Adults - Insights from the Three-dimensional Speckle-tracking Echocardiographic MAGYAR-Healthy Study. REVIEWS IN CARDIOVASCULAR MEDICINE, 25 (2). ISSN 1530-6550 (2024)

الإتاحة: https://doi.org/10.31083/j.rcm2502053Test
http://publicatio.bibl.u-szeged.hu/29492Test/
http://publicatio.bibl.u-szeged.hu/29492/1/Nemes.pdfTest

المؤلفون: Andréka, Judit, Sasi, Viktor, Tóth, Gábor G., Ruzsa, Zoltán

المصدر: Catheterization and Cardiovascular Interventions ; volume 103, issue 5, page 803-807 ; ISSN 1522-1946 1522-726X

الوصف: In this paper, a case of an 82‐year‐old man who was admitted to our department with sever symptomatic degenerative aortic valve stenosis is presented and discussed. After all screening procedures, a successful transfemoral transcatheter aortic valve replacement was performed, but the closure of the femoral access was unsuccessful due to suture‐based device failure. We decided to perform a prolonged balloon dilatation and external compression at the bleeding site, but the bleeding did not stop; therefore, an iCover stent graft was implanted from distal radial artery access using slender technique. Following that, the bleeding was stopped, and the patient had an uneventful outcome.

الإتاحة: https://doi.org/10.1002/ccd.31001Test

المؤلفون: Achim, Alexandru, Jambrik, Zoltan, Nagy, Ferenc, Ruzsa, Zoltan

المساهمون: Cankovic, Milenko Zoran, Sen, Gautam, Musumeci, Giuseppe

المصدر: European Heart Journal - Case Reports ; volume 8, issue 5 ; ISSN 2514-2119

الإتاحة: https://doi.org/10.1093/ehjcr/ytae229Test
https://academic.oup.com/ehjcr/article-pdf/8/5/ytae229/57451150/ytae229.pdfTest

المؤلفون: Saba, Luca, Maindarkar, Mahesh, Khanna, Narendra N, Johri, Amer M, Mantella, Laura, Laird, John R, Paraskevas, Kosmas I, Ruzsa, Zoltan, Kalra, Manudeep K, Fernandes, Jose Fernandes E, Chaturvedi, Seemant, Nicolaides, Andrew, Rathore, Vijay, Singh, Narpinder, Fouda, Mostafa M, Isenovic, Esma R, Al-Maini, Mustafa, Viswanathan, Vijay, Suri, Jasjit S

المساهمون: Saba, Luca, Maindarkar, Mahesh, Khanna, Narendra N, Johri, Amer M, Mantella, Laura, Laird, John R, Paraskevas, Kosmas I, Ruzsa, Zoltan, Kalra, Manudeep K, Fernandes, Jose Fernandes E, Chaturvedi, Seemant, Nicolaides, Andrew, Rathore, Vijay, Singh, Narpinder, Fouda, Mostafa M, Isenovic, Esma R, Al-Maini, Mustafa, Viswanathan, Vijay, Suri, Jasjit S

مصطلحات موضوعية: Bia, Biomarker, Cardiovascular disease, Cloud, Deep learning, Explainable artificial intelligence, Genomic, Multicenter, Pharmaceutical, Pruning, Radiomic, Stroke

الوصف: Background: Cardiovascular disease (CVD) is challenging to diagnose and treat since symptoms appear late during the progression of atherosclerosis. Conventional risk factors alone are not always sufficient to properly categorize at-risk patients, and clinical risk scores are inadequate in predicting cardiac events. Integrating genomic-based biomarkers (GBBM) found in plasma/serum samples with novel non-invasive radiomics-based biomarkers (RBBM) such as plaque area, plaque burden, and maximum plaque height can improve composite CVD risk prediction in the pharmaceutical paradigm. These biomarkers consider several pathways involved in the pathophysiology of atherosclerosis disease leading to CVD. Objective: This review proposes two hypotheses: (i) The composite biomarkers are strongly correlated and can be used to detect the severity of CVD/Stroke precisely, and (ii) an explainable artificial intelligence (XAI)-based composite risk CVD/Stroke model with survival analysis using deep learning (DL) can predict in preventive, precision, and personalized (aiP3) framework benefiting the pharmaceutical paradigm. Method: The PRISMA search technique resulted in 214 studies assessing composite biomarkers using radiogenomics for CVD/Stroke. The study presents a XAI model using AtheroEdgeTM 4.0 to determine the risk of CVD/Stroke in the pharmaceutical framework using the radiogenomics biomarkers. Conclusions: Our observations suggest that the composite CVD risk biomarkers using radiogenomics provide a new dimension to CVD/Stroke risk assessment. The proposed review suggests a unique, unbiased, and XAI model based on AtheroEdgeTM 4.0 that can predict the composite risk of CVD/Stroke using radiogenomics in the pharmaceutical paradigm.

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37919080; info:eu-repo/semantics/altIdentifier/wos/WOS:001106813700016; volume:28; issue:10; numberofpages:24; journal:FRONTIERS IN BIOSCIENCE; https://hdl.handle.net/11584/388283Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85176200449

الإتاحة: https://doi.org/10.31083/j.fbl2810248Test
https://hdl.handle.net/11584/388283Test

المؤلفون: Khanna, Narendra N, Singh, Manasvi, Maindarkar, Mahesh, Kumar, Ashish, Johri, Amer M, Mentella, Laura, Laird, John R, Paraskevas, Kosmas I, Ruzsa, Zoltan, Singh, Narpinder, Kalra, Mannudeep K, Fernandes, Jose Fernandes E, Chaturvedi, Seemant, Nicolaides, Andrew, Rathore, Vijay, Singh, Inder, Teji, Jagjit S, Al-Maini, Mostafa, Isenovic, Esma R, Viswanathan, Vijay, Khanna, Puneet, Fouda, Mostafa M, Saba, Luca, Suri, Jasjit S

المساهمون: Khanna, Narendra N, Singh, Manasvi, Maindarkar, Mahesh, Kumar, Ashish, Johri, Amer M, Mentella, Laura, Laird, John R, Paraskevas, Kosmas I, Ruzsa, Zoltan, Singh, Narpinder, Kalra, Mannudeep K, Fernandes, Jose Fernandes E, Chaturvedi, Seemant, Nicolaides, Andrew, Rathore, Vijay, Singh, Inder, Teji, Jagjit S, Al-Maini, Mostafa, Isenovic, Esma R, Viswanathan, Vijay, Khanna, Puneet, Fouda, Mostafa M, Saba, Luca, Suri, Jasjit S

مصطلحات موضوعية: Artificial Intelligence, Cardiovascular Disease, Genomic, Polygenic Risk Score, Precision Medicine

الوصف: Cardiovascular disease (CVD) related mortality and morbidity heavily strain society. The relationship between external risk factors and our genetics have not been well established. It is widely acknowledged that environmental influence and individual behaviours play a significant role in CVD vulnerability, leading to the development of polygenic risk scores (PRS). We employed the PRISMA search method to locate pertinent research and literature to extensively review artificial intelligence (AI)-based PRS models for CVD risk prediction. Furthermore, we analyzed and compared conventional vs. AI-based solutions for PRS. We summarized the recent advances in our understanding of the use of AI-based PRS for risk prediction of CVD. Our study proposes three hypotheses: i) Multiple genetic variations and risk factors can be incorporated into AI-based PRS to improve the accuracy of CVD risk predicting. ii) AI-based PRS for CVD circumvents the drawbacks of conventional PRS calculators by incorporating a larger variety of genetic and non-genetic components, allowing for more precise and individualised risk estimations. iii) Using AI approaches, it is possible to significantly reduce the dimensionality of huge genomic datasets, resulting in more accurate and effective disease risk prediction models. Our study highlighted that the AI-PRS model outperformed traditional PRS calculators in predicting CVD risk. Furthermore, using AI-based methods to calculate PRS may increase the precision of risk predictions for CVD and have significant ramifications for individualized prevention and treatment plans.

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/38013648; info:eu-repo/semantics/altIdentifier/wos/WOS:001112924300006; volume:38; issue:46; numberofpages:32; journal:JOURNAL OF KOREAN MEDICAL SCIENCE; https://hdl.handle.net/11584/384164Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85179437659

الإتاحة: https://doi.org/10.3346/jkms.2023.38.e395Test
https://hdl.handle.net/11584/384164Test

المؤلفون: Sasi Viktor, Szántó Gyula Tamás, Achim Alexandru, Ungi Imre, Varga Albert, Ruzsa Zoltán

مصطلحات موضوعية: 03.02. Klinikai orvostan

وصف الملف: text

العلاقة: http://publicatio.bibl.u-szeged.hu/29529/1/Sasi.pdfTest; Sasi Viktor; Szántó Gyula Tamás; Achim Alexandru; Ungi Imre; Varga Albert; Ruzsa Zoltán: Combination of laser atherectomy and super high-pressure non-compliant balloon to treat stent under-expansion in cases of failed interventional options. INTERVENTIONAL CARDIOLOGY, 18. ISSN 1755-5302 (2023)

الإتاحة: https://doi.org/10.15420/icr.2022.36Test
http://publicatio.bibl.u-szeged.hu/29529Test/
http://publicatio.bibl.u-szeged.hu/29529/1/Sasi.pdfTest

المؤلفون: Ludman Peter, Zeymer Uwe, Danchin Nicolas, Kala Petr, Laroche Cecile, Sadeghi Masoumeh, Caporale Roberto, Shaheen Sameh Mohamed, Legutko Jacek, Iakobishvili Zaza, Alhabib Khalid F., Motovska Zuzana, Studencan Martin, Mimoso Jorge, Becker Dávid, Kollaborációs szervezet: ESC, Ruzsa Zoltán

مصطلحات موضوعية: 03.02. Klinikai orvostan

الوصف: Aims To use quality indicators to study the management of ST-segment elevation myocardial infarction (STEMI) in different regions. Methods and results Prospective cohort study of STEM I within 24 h of symptom onset (11 462 patients, 196 centres, 26 European Society of Cardiology members, and 3 affiliated countries). The median delay between arrival at a percutaneous cardiovascular intervention (PCI) centre and primary PCI was 40 min (interquartile range 20-74) with 65.8% receiving PCI within guideline recommendation of 60 min. A third of patients (33.2%) required transfer from their initial hospital to one that could perform emergency PCI for whom only 27.2% were treated within the quality indicator recommendation of 120 min. Radial access was used in 56.6% of all primary PCI, but with large geographic variation, from 76.4 to 9.1%. Statins were prescribed at discharge to 98.7% of patients, with little geographic variation. Of patients with a history of heart failure or a documented left ventricular ejection fraction <= 40%, 84.0% were discharged on an angiotensin-converting enzyme inhibitor/angiotensin receptor blocker and 88.7% were discharged on beta-blockers. Conclusion Care for STEMI shows wide geographic variation in the receipt of timely primary PCI, and is in contrast with the more uniform delivery of guideline-recommended pharmacotherapies at time of hospital discharge. [GRAPHICS] .

وصف الملف: text

العلاقة: http://publicatio.bibl.u-szeged.hu/29314/1/Ludman.pdfTest; Ludman Peter; Zeymer Uwe; Danchin Nicolas; Kala Petr; Laroche Cecile; Sadeghi Masoumeh; Caporale Roberto; Shaheen Sameh Mohamed; Legutko Jacek; Iakobishvili Zaza; Alhabib Khalid F.; Motovska Zuzana; Studencan Martin; Mimoso Jorge; Becker Dávid; Kollaborációs szervezet: ESC; Ruzsa Zoltán; et al. (kollab. közrem.): Care of patients with ST-elevation myocardial infarction: an international analysis of quality indicators in the acute coronary syndrome STEMI Registry of the EURObservational Research Programme and ACVC and EAPCI Associations of the European Society of Cardiology in 11 462 patients. EUROPEAN HEART JOURNAL: ACUTE CARDIOVASCULAR CARE, 12 (1). pp. 22-37. ISSN 2048-8726 (2023)

الإتاحة: https://doi.org/10.1093/ehjacc/zuac143Test
http://publicatio.bibl.u-szeged.hu/29314Test/
http://publicatio.bibl.u-szeged.hu/29314/1/Ludman.pdfTest

المؤلفون: Nagy Ferenc Tamás, Olajos Dorottya Lilla, Vattay Borbála, Borzsák Sarolta, Boussoussou Melinda, Deák Mónika, Vecsey-Nagy Milán, Sipos Barbara, Jermendy Ádám Levente, Tóth Gábor G., Nemes Balázs, Merkely Béla Péter, Szili-Török Tamás, Ruzsa Zoltán, Szilveszter Bálint

مصطلحات موضوعية: 03.02. Klinikai orvostan

وصف الملف: text

العلاقة: http://publicatio.bibl.u-szeged.hu/29104/1/NagyF.pdfTest; Nagy Ferenc Tamás; Olajos Dorottya Lilla; Vattay Borbála; Borzsák Sarolta; Boussoussou Melinda; Deák Mónika; Vecsey-Nagy Milán; Sipos Barbara; Jermendy Ádám Levente; Tóth Gábor G.; Nemes Balázs; Merkely Béla Péter; Szili-Török Tamás; Ruzsa Zoltán; Szilveszter Bálint: Dynamic Perfusion Computed Tomography for the Assessment of Concomitant Coronary Artery Disease in Patients with a History of Percutaneous Transluminal Angioplasty for Chronic Limb-Threatening Ischemia—A Pilot Study. JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE, 10 (11). ISSN 2308-3425 (2023)

الإتاحة: https://doi.org/10.3390/jcdd10110443Test
http://publicatio.bibl.u-szeged.hu/29104Test/
http://publicatio.bibl.u-szeged.hu/29104/1/NagyF.pdfTest