المؤلفون: Rongmei Liu, Qiuping Zhao, Wenyong Dong, Dan Guo, Zhanlei Shen, Yi Li, Wanliang Zhang, Dongfang Zhu, Jingbao Zhang, Junwen Bai, Ruizhe Ren, Mingyue Zhen, Jiajia Zhang, Jinxin Cui, Xinran Li, Yudong Miao

المصدر: BMC Health Services Research, Vol 24, Iss 1, Pp 1-11 (2024)

مصطلحات موضوعية: Primary healthcare personnel, Public health service capability, Urban and rural areas, Public aspects of medicine, RA1-1270

الوصف: Abstract Background The public health service capability of primary healthcare personnel directly affects the utilization and delivery of health services, and is influenced by various factors. This study aimed to examine the status, factors, and urban-rural differences of public health service capability among primary healthcare personnel, and provided suggestions for improvement. Methods We used cluster sampling to survey 11,925 primary healthcare personnel in 18 regions of Henan Province from 20th to March 31, 2023. Data encompassing demographics and public health service capabilities, including health lifestyle guidance, chronic disease management, health management of special populations, and vaccination services. Multivariable regression analysis was employed to investigate influencing factors. Propensity Score Matching (PSM) quantified urban-rural differences. Results The total score of public health service capability was 80.17 points. Chronic disease management capability scored the lowest, only 19.60. Gender, education level, average monthly salary, professional title, health status, employment form, work unit type, category of practicing (assistant) physician significantly influenced the public health service capability (all P

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1472-6963Test

الوصول الحر: https://doaj.org/article/ef4d36791e404ee98371beb05bce0998Test

المؤلفون: Yudong Miao, Wanliang Zhang, Yi Li, Jian Wu, Zhanlei Shen, Junwen Bai, Dongfang Zhu, Ruizhe Ren, Jingbao Zhang, Dan Guo, Clifford Silver Tarimo, Chengpeng Li, Wenyong Dong

المصدر: BMC Public Health, Vol 23, Iss 1, Pp 1-15 (2023)

مصطلحات موضوعية: COVID-19 Infection, Lifestyle behavior, Emotional expressivity, China, Public aspects of medicine, RA1-1270

الوصف: Abstract Background COVID-19 is still prevalent in most countries around the world at the low level. Residents’ lifestyle behaviors and emotions are critical to prevent COVID-19 and keep healthy, but there is lacking of confirmative evidence on how residents’ lifestyle behaviors and emotional expressivity affected COVID-19 infection. Methods Baseline study was conducted in August 2022 and follow-up study was conducted in February 2023. Baseline survey collected information on residents’ basic information, as well as their lifestyle behaviors and emotions. Follow-up study was carried out to gather data on COVID-19 infection condition. Binary logistic regression was utilized to identify factors that may influence COVID-19 infection. Attributable risk (AR) was computed to determine the proportion of unhealthy lifestyle behaviors and emotional factors that could be attributed to COVID-19 infection. Sensitivity analysis was performed to test the robustness of the results. Results A total of 5776 participants (46.57% males) were included in this study, yielding an overall COVID-19 infection rate of 54.8% (95%CI: 53.5 – 56.0%). The findings revealed that higher stress levels [aOR = 1.027 (95%CI; 1.005–1.050)] and lower frequency in wearing masks, washing hands, and keeping distance [aOR = 1.615 (95%CI; 1.087–2.401)], were positively associated with an increased likelihood of COVID-19 infection (all P

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1471-2458Test

الوصول الحر: https://doaj.org/article/4f326dcf85b3462c8165840bcbfb71a4Test

المؤلفون: Yudong Miao, Jingbao Zhang, Zhanlei Shen, Yi Li, Wanliang Zhang, Junwen Bai, Dongfang Zhu, Ruizhe Ren, Dan Guo, Clifford Silver Tarimo, Wenyong Dong, Qiuping Zhao, Jianping Hu, Miaojun Li, Rongmei Liu

المصدر: Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)

مصطلحات موضوعية: Free vaccination behavior, urban and rural, China, propensity score matching, interaction analysis, Immunologic diseases. Allergy, RC581-607, Therapeutics. Pharmacology, RM1-950

الوصف: This study aimed to evaluate how the duration of travel affects the behavior of urban and rural residents regarding free COVID-19 vaccination, and provide scientific evidence for promoting free vaccination and building an immune barrier to cope with future epidemics. From August 3, 2022 to February,18,2023, A follow-up survey was conducted in urban and rural adults in four cities in China to collect information on socio-demographic factors, vaccination status and travel time for vaccination. Propensity score matching (PSM) analysis was deployed to measure the net difference of the enhanced vaccination rate between urban and rural residents in different traffic time distribution. A total of 5780 samples were included in the study. The vaccination rate of the booster dose of COVID-19 vaccine among rural residents was higher than that of urban residents with a significant P-value (69.36% VS 64.49%,p

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2164-5515Test; https://doaj.org/toc/2164-554XTest

الوصول الحر: https://doaj.org/article/ba3c61f44c654a7ab2c5ad8e26f637e0Test

المؤلفون: Yudong Miao, Junwen Bai, Zhanlei Shen, Yi Li, Wanliang Zhang, Dongfang Zhu, Ruizhe Ren, Jingbao Zhang, Dan Guo, Clifford Silver Tarimo, Wenyong Dong, Rongmei Liu, Qiuping Zhao, Jianping Hu, Miaojun Li, Wei Wei

المصدر: Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)

مصطلحات موضوعية: COVID-19 booster vaccine, vaccine hesitancy, PSM analysis, urban-rural differences, China, Immunologic diseases. Allergy, RC581-607, Therapeutics. Pharmacology, RM1-950

الوصف: ABSTRACTDuring the COVID-19 pandemic, the vaccine hesitancy has significantly affected the vaccination. To evaluate the booster vaccine hesitancy and its influencing factors among urban and rural residents, as well as to estimate the net difference of booster vaccine hesitancy between urban and rural residents. We conducted a nationwide, cross-sectional Internet survey on 1–8 February 2023, and employed stratified random sampling technique to select participants (≥18 years old) from urban and rural areas. Multivariate logistic regression was used to determine the factors impacting booster vaccine hesitancy. Propensity Score Matching was used to estimate the net difference of COVID-19 booster vaccine hesitancy between urban and rural residents. The overall COVID-19 booster vaccine hesitancy rate of residents was 28.43%. The COVID-19 booster vaccine hesitancy rate among urban residents was found to be 34.70%, among rural residents was 20.25%. Chronic diseases, infection status, vaccination benefits, and trust in vaccine developers were associated with booster vaccine hesitancy among urban residents. Barriers of vaccination were associated with booster vaccine hesitancy among rural residents. PSM analysis showed that the urban residents have a higher booster vaccine hesitancy rate than rural residents, with a net difference of 6.20%. The vaccine hesitancy rate increased significantly, and the urban residents have a higher COVID-19 booster vaccine hesitancy than rural residents. It becomes crucial to enhance the dissemination of information regarding the advantages of vaccination and foster greater trust among urban residents toward the healthcare system.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2164-5515Test; https://doaj.org/toc/2164-554XTest

الوصول الحر: https://doaj.org/article/6e602ba4e9fd459e999026223250650aTest

المؤلفون: Yudong Miao, Wanliang Zhang, Yi Li, Jian Wu, Zhanlei Shen, Junwen Bai, Dongfang Zhu, Ruizhe Ren, Jingbao Zhang, Dan Guo, Clifford Silver Tarimo, Chengpeng Li, Wenyong Dong

مصطلحات موضوعية: Medicine, Biotechnology, Science Policy, Mental Health, Infectious Diseases, Virology, Computational Biology, COVID-19 Infection, Lifestyle behavior, Emotional expressivity, China

الوصف: Supplementary Material 1

العلاقة: https://figshare.com/articles/journal_contribution/Additional_file_1_of_Quantifying_the_benefits_of_healthy_lifestyle_behaviors_and_emotional_expressivity_in_lowering_the_risk_of_COVID-19_infection_a_national_survey_of_Chinese_population/24708979Test

الإتاحة: https://doi.org/10.6084/m9.figshare.24708979.v1Test
https://figshare.com/articles/journal_contribution/Additional_file_1_of_Quantifying_the_benefits_of_healthy_lifestyle_behaviors_and_emotional_expressivity_in_lowering_the_risk_of_COVID-19_infection_a_national_survey_of_Chinese_population/24708979Test

المؤلفون: Jielong Li, Diwei Liu, Ruizhe Ren, Chuanhong Xiao, Zongjun Shi, Tao Zhao, Min Hu, Yanyu Wei, Zhaoyun Duan, Yubin Gong, Zhenhua Wu

المصدر: IEEE Transactions on Electron Devices. 70:2780-2785

مصطلحات موضوعية: Electrical and Electronic Engineering, Electronic, Optical and Magnetic Materials

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::400de6aab0f95bf8de3a97e3f4ba2516Test
https://doi.org/10.1109/ted.2022.3232312Test

المؤلفون: Ruizhe Ren, Kefan Ma, Yuanqing Jiang, Junbo Chen, Yaohui Kou, Zhen Ge, Zhaoming Chen, Xiyang Wei, Luyang Yu

المصدر: American Journal of Physiology-Cell Physiology. 324:C407-C419

مصطلحات موضوعية: Physiology, Cell Biology

الوصف: Angiogenesis is involved in development, reproduction, wound healing, homeostasis, and other pathophysiological events. Imbalanced angiogenesis predisposes patients to various pathological processes, such as angiocardiopathy, inflammation, and tumorigenesis. MicroRNAs (miRNAs) have been found to be important in regulating cellular processing and physiological events including angiogenesis. However, the role of miRNAs that regulate angiogenesis (angiomiRs) is not fully understood. Here, we observed a downregulation of the miR-196 family in endothelial cells upon hypoxia. Functionally, miR-196b-5p inhibited the angiogenic functions of endothelial cells in vitro and suppressed angiogenesis in Matrigel plugs and skin wound healing in vivo. Mechanistically, miR-196b-5p bound onto the 3′ untranslated region (UTR) of high-mobility group AT-hook 2 (HMGA2) mRNA and repressed the translation of HMGA2, which in turn represses HIF1α accumulation in endothelial cells upon hypoxia. Together, our results establish the role of endothelial miR-196b-5p as an angiomiR that negatively regulates endothelial growth in angiogenesis via the hypoxia/miR-196b-5p/HMGA2/HIF1α loop. miR-196b-5p and its regulatory loop could be an important addition to the molecular mechanisms underlying angiogenesis and may serve as potential targets for antiangiogenic therapy.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6cd311e1611d8bbd071bdd4530f217Test
https://doi.org/10.1152/ajpcell.00309.2022Test

المؤلفون: Ruizhe Ren, Sha Ding, Kefan Ma, Yuanqing Jiang, Yiran Wang, Junbo Chen, Yunyun Wang, Yaohui Kou, Xiao Fan, Xiaolong Zhu, Lingfeng Qin, Cong Qiu, Simons, Michael, Xiyang Wei, Luyang Yu

المصدر: Circulation Research; 1/19/2024, Vol. 134 Issue 2, p203-222, 20p

المؤلفون: Xiaofei Zhou, Yuanqing Jiang, Yuewen Wang, Linge Fan, Yunhui Zhu, Yefeng Chen, Yiran Wang, Yingyi Zhu, Hongkun Wang, Zihang Pan, Zhoubin Li, Xiaolong Zhu, Ruizhe Ren, Zhen Ge, Dongwu Lai, En Yin Lai, Ting Chen, Kai Wang, Ping Liang, Lingfeng Qin

المصدر: Circulation Research; Sep2023, Vol. 133 Issue 6, p508-531, 24p

المؤلفون: John K. Cowell, Josephine Tidwell, Ruizhe Ren, Haiyan Qin, Mingqiang Ren

الوصف: PDF file - 138K

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313c333003cf72abd3bbbf58d0ab8392Test
https://doi.org/10.1158/0008-5472.22389407.v1Test