المؤلفون: Beck, Danielle, Asghar, Aliya, Kenworthy-Heinige, Tawni, Johnson, Marcus R, Willis, Cyenthia, Kantorowicz, Alexandra S, Condon, Debra L, Huang, Grant D, VA Cooperative Studies Program (CSP) Network of Dedicated Enrollment Sites (NODES)

مصطلحات موضوعية: VA Cooperative Studies Program (CSP) Network of Dedicated Enrollment Sites, Access to research, Innovative enrollment strategies, Mobile recruitment, Recruitment barriers, Veteran research

الوصف: Background:Access to healthcare delivery programs and systems is a primary correlate to the overall health and well-being of Veterans and the general population. Participation in clinical research is a gateway to novel therapies that are intended to address current global health issues. Meeting or exceeding recruitment goals in clinical research is one of the key determinants of the timely and successful completion of a study. The travel and time burdens experienced by study participants are often considered barriers to their enrollment into clinical research. The Department of Veterans Affairs (VA) Cooperative Studies Program (CSP) established a consortium of nine VA medical centers (VAMCs) called the Network of Dedicated Enrollment Sites (NODES). The NODES program provides study site-level expertise and innovative approaches that address challenges to clinical research execution. In alignment with our mission, our program developed an approach to increase study participant access to clinical research through implementing "Mobile Recruitment (MoRe)" units. This manuscript describes the utility and challenges associated with employing this strategy to address three common barriers to clinical research participation: 1) research participant travel burden, 2) participant access to study opportunities, and 3) low participant enrollment. Methods:A plan to introduce the Mobile Recruitment (MoRe) unit as a recruitment strategy was piloted for a high-volume, observational cohort study and mega biobank in the VA health care system, the "Million Veteran Program (MVP)". MoRe is a recruitment strategy for CSP research integrating mobile technology and atypical research recruitment locations. Recruitment locations include primary or main VA hospitals and their assigned VA Community-Based Outpatient Clinics (CBOCs). Each Node site (n = 9) received components of the MoRe unit including a laptop, printer, portable cart with storage space, cooler/ice packs for specimen storage and transport. Each site's usage of these components varied based on its respective needs. Activities focused on both VA main facilities and CBOC facilities for recruitment. Results:Seven of the nine Node sites compared the effectiveness of the MoRe unit on MVP study enrollment outcomes over three-time points: pre-intervention period, intervention period, and post-intervention period. The utilization of MoRe in the intervention period demonstrated a 36.9% increase in enrollment compared to the previous six months (pre-intervention period). There was a 2% enrollment increase at the six-month post-intervention period as compared to the intervention period. When comparing the pre-intervention period to the post-intervention period (duration of eighteen months), enrollment increased by 38.9%. Conclusion:Five of the seven sites experienced an increase in enrollment during the intervention and post-intervention periods. The two sites without an increase in enrollment experienced various extenuating factors. Characteristics of sites using MoRe included the ability to utilize a smaller, unconventional space, i.e. not a traditional clinical research exam space for recruitment. MoRe was utilized in hospital laboratory space, CBOCs, primary care clinics, and other subspecialty clinics that allowed recruitment activities but did not have dedicated space to offer the research teams for that purpose. This initiative successfully demonstrated the benefit of deploying the unit, proving its utility in cases in where there was a lack of space or alternative workstations for research activities. The implementation of MoRe by NODES as a recruitment strategy for MVP may be transferable to other VA clinical research studies, as well as to other healthcare settings executing similar clinical research activities.

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5bn368z5Test

المؤلفون: Reymert, Ingvild, Vabø, Agnete, Borlaug, Siri Brorstad, Jungblut, Jens Patrick Wilhelm

المصدر: Higher Education ; 1-21

مصطلحات موضوعية: Excellence, Recruitment barriers, Academic professions, Survey data, Cross-country studies

الوصف: Recruitment is one of the main strategic tools for universities, which aim to hire the best possible candidates for their academic positions. However, not every institution can hire whom they perceive as the best. Our paper investigates what are perceived to be the most pressing hindrances to attracting the best researchers. We focus on national and disciplinary differences in researchers’ perceptions of barriers to recruiting the best scholars in their fields. We surveyed researchers in economics and physics in the Netherlands, Norway, and the UK and fnd that economists emphasize salary level and institutional prestige as the main barriers, while physicists underline competition from non-academic actors and career development opportunities. We further find differences by country. In Norway, limited institutional prestige is a key barrier to attracting the best researchers, while researchers in the UK highlight salary levels. Respondents at Dutch universities claim that they experience multiple, equally important barriers. ; publishedVersion

وصف الملف: application/pdf

العلاقة: Higher Education; Higher Education. 2022, 1-21.; urn:issn:0018-1560; urn:issn:1573-174X; https://hdl.handle.net/11250/3049799Test; https://doi.org/10.1007/s10734-022-00967-wTest; cristin:2082998

الإتاحة: https://doi.org/10.1007/s10734-022-00967-wTest
https://hdl.handle.net/11250/3049799Test

المؤلفون: Martin Nagl‐Cupal, Julia Hauprich

المصدر: Nursing Open, Vol 7, Iss 4, Pp 1164-1172 (2020)

مصطلحات موضوعية: evaluation of services, family caregiving, family support, qualitative research, recruitment barriers, young carers, Nursing, RT1-120

الوصف: Abstract Aims To evaluate why no families could be recruited for a nurse‐led and family‐centred support programme in Austria which aimed to prevent an age‐inappropriate caring role for young carers. Design A qualitative study incorporating qualitative e‐interviews and telephone interviews. Method Twenty‐one interviews were conducted with statistically significant project stakeholders (N = 17) and with adult family members of children with caring responsibilities (N = 4). Data collection and analysis were guided by the “Social Marketing Framework.” Relevant statements were assigned to the main categories: product; price; promotion; place; and working with partners. Results The lack of awareness towards young carers, the unfamiliar, open outcome approach of the intervention, the inappropriate language used in promotional materials and the families' fear of stigma while seeking support were identified as central obstacles for successful recruitment of families and implementation of the support programme.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2054-1058Test

الوصول الحر: https://doaj.org/article/53b26b93b3b648f0bd78b08a14e03e55Test

المؤلفون: Danielle Beck, Aliya Asghar, Tawni Kenworthy-Heinige, Marcus R. Johnson, Cyenthia Willis, Alexandra S. Kantorowicz, Debra L. Condon, Grant D. Huang, Terence M. Keane, Pantel S. Vokonas, Dan Darroch, James LePage, Jennifer Compton, David Leehey, Conor McBurney, Stephanie Keen, Panagiotis Kougias, Sarah Perusich, Michael E. DeBakey, Timothy Morgan, Karyn Isip, Selcuk Adabag, Marti Donaire, Debra K. Johnson, Trisha Suppes, Karen Bratcher, Ann N. Roseman, Merritt Raitt, Daniel Clegg, Jennifer Romesser, Kandi Velarde, Cicilia Velarde, Christina Nessler, Sunder Mudaliar, Murray Stein, Catherine DeLue

المصدر: Contemporary Clinical Trials Communications, Vol 19, Iss , Pp 100623- (2020)

مصطلحات موضوعية: Mobile recruitment, Recruitment barriers, Veteran research, Access to research, Innovative enrollment strategies, Medicine (General), R5-920

الوصف: Background: Access to healthcare delivery programs and systems is a primary correlate to the overall health and well-being of Veterans and the general population. Participation in clinical research is a gateway to novel therapies that are intended to address current global health issues. Meeting or exceeding recruitment goals in clinical research is one of the key determinants of the timely and successful completion of a study. The travel and time burdens experienced by study participants are often considered barriers to their enrollment into clinical research. The Department of Veterans Affairs (VA) Cooperative Studies Program (CSP) established a consortium of nine VA medical centers (VAMCs) called the Network of Dedicated Enrollment Sites (NODES). The NODES program provides study site-level expertise and innovative approaches that address challenges to clinical research execution. In alignment with our mission, our program developed an approach to increase study participant access to clinical research through implementing “Mobile Recruitment (MoRe)” units. This manuscript describes the utility and challenges associated with employing this strategy to address three common barriers to clinical research participation: 1) research participant travel burden, 2) participant access to study opportunities, and 3) low participant enrollment. Methods: A plan to introduce the Mobile Recruitment (MoRe) unit as a recruitment strategy was piloted for a high-volume, observational cohort study and mega biobank in the VA health care system, the “Million Veteran Program (MVP)”. MoRe is a recruitment strategy for CSP research integrating mobile technology and atypical research recruitment locations. Recruitment locations include primary or main VA hospitals and their assigned VA Community-Based Outpatient Clinics (CBOCs). Each Node site (n = 9) received components of the MoRe unit including a laptop, printer, portable cart with storage space, cooler/ice packs for specimen storage and transport. Each site's usage of these components varied based on its respective needs. Activities focused on both VA main facilities and CBOC facilities for recruitment. Results: Seven of the nine Node sites compared the effectiveness of the MoRe unit on MVP study enrollment outcomes over three-time points: pre-intervention period, intervention period, and post-intervention period. The utilization of MoRe in the intervention period demonstrated a 36.9% increase in enrollment compared to the previous six months (pre-intervention period). There was a 2% enrollment increase at the six-month post-intervention period as compared to the intervention period. When comparing the pre-intervention period to the post-intervention period (duration of eighteen months), enrollment increased by 38.9%. Conclusion: Five of the seven sites experienced an increase in enrollment during the intervention and post-intervention periods. The two sites without an increase in enrollment experienced various extenuating factors. Characteristics of sites using MoRe included the ability to utilize a smaller, unconventional space, i.e. not a traditional clinical research exam space for recruitment. MoRe was utilized in hospital laboratory space, CBOCs, primary care clinics, and other subspecialty clinics that allowed recruitment activities but did not have dedicated space to offer the research teams for that purpose. This initiative successfully demonstrated the benefit of deploying the unit, proving its utility in cases in where there was a lack of space or alternative workstations for research activities. The implementation of MoRe by NODES as a recruitment strategy for MVP may be transferable to other VA clinical research studies, as well as to other healthcare settings executing similar clinical research activities.

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2451865420301071Test; https://doaj.org/toc/2451-8654Test

الوصول الحر: https://doaj.org/article/acce5080d1f448978eeb9af98354d2a1Test

المؤلفون: Birthe Andrea Lehmann, Lara Lindert, Silke Ohlmeier, Lara Schlomann, Holger Pfaff, Kyung-Eun Choi

المصدر: International Journal of Environmental Research and Public Health; Volume 17; Issue 6; Pages: 1886

مصطلحات موضوعية: recruitment barriers, randomization, RCT, qualitative research, case managers

جغرافية الموضوع: agris

الوصف: Background: Randomized controlled trials (RCTs) are regarded as the most internally valid means of estimating the effectiveness of complex public health interventions, but the recruitment of participants can be difficult. The aim of this study was to explore factors that may have affected the recruitment of employees with musculoskeletal disorders (MSDs) to a multicenter worksite health promotion program from the perspective of recruiting case managers. Methods: Factors in recruitment to the RCT were explored using three focus group discussions with case managers. Data were processed using MAXQDA and analyzed with a combination of content and sequence analysis. Results: Findings showed that randomization is a major challenge for recruitment. Case managers adapted their communication with, and approaches to possible participants because of the randomization design and employed coping strategies to compensate for allocation into the control arm of the study. Perceptions of the superiority of the intervention group over the control group, perceptions of the (mis)match of participants to one of the groups, as well as the understanding of the necessity of randomization for effectiveness evaluations, further affected recruitment. Perceived expectations of possible participants and their (emotional) reactions to the randomization allocation also complicated recruitment. Conclusion: We were able to gain insight into the challenges of randomization for the recruitment of participants to a multicenter RCT. This study assisted the development of strategies to overcome barriers in the ongoing implementation process of the trial (i.e., the adaption of best practice information sheets and newsletters). There remains a need to develop effective interventions to help those recruiting to trials.

وصف الملف: application/pdf

العلاقة: https://dx.doi.org/10.3390/ijerph17061886Test

الإتاحة: https://doi.org/10.3390/ijerph17061886Test

المؤلفون: Schneider, Christine, author, Kahana, Eva, author

المصدر: Research Involving Participants with Cognitive Disability and Difference : Ethics, Autonomy, Inclusion, and Innovation, 2019.

الإتاحة: https://doi.org/10.1093/oso/9780198824343.003.0009Test

المؤلفون: Ganz, Patricia A., Land, Stephanie R., Antonio, Cynthia, Zheng, Ping, Yothers, Greg, Petersen, Laura, Wickerham, D. Lawrence, Wolmark, N., Ko, Clifford Y.

المصدر: Journal of Cancer Survivorship: Research and Practice. 3(3)

مصطلحات موضوعية: Medicine & Public Health, Primary Care Medicine, Quality of Life Research, Health Informatics, Health Promotion and Disease Prevention, Oncology, Public Health/Gesundheitswesen, Colorectal cancer survivors, Clinical trials, Recruitment barriers

الوصف: With the growing number of adult cancer survivors, there is increasing need for information that links potential late and long term effects with specific treatment regimens. Few adult cancer patients are treated on clinical trials; however, patients previously enrolled in these trials are an important source of information about treatment-related late effects.Focusing on colorectal cancer survivors, we used the database from five phase III randomized clinical trials from the National Surgical Adjuvant Breast & Bowel Project (NSABP) to recruit and enroll long term survivors in a study of late health outcomes and quality of life. We describe the challenges to recruitment of patients more than 5 –20 years after treatment.Sixty-five NSABP treatment sites were invited to enroll patients in the study. Sixty participated with the potential to recruit 2,408 patients. We received registration forms on only 976 patients (41%) of whom 744 (76%) expressed interest in participating and 708 completed interviews (95% of those expressing interest; 29% of total potential sample). There were multiple barriers to recruitment (difficulty locating patients, lack of institutional commitment, lack of patient interest).Patients treated on clinical trials are an important potential source for examining the late effects of cancer treatments. Retrospective recruitment has substantial limitations. In the future, mechanisms should be established for prospective long-term follow-up to identify and understand the frequency and type of late effects associated with cancer treatments.As cancer patients are living longer, it will be important to learn from participants in clinical trials whether or not specific treatment regimens are associated with any serious late effects.

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8th7f420Test

المؤلفون: Ingvild Reymert, Agnete Vabø, Siri B. Borlaug, Jens Jungblut

المصدر: Journal of Higher Education
Higher Education

مصطلحات موضوعية: Recruitment barriers, Survey data, Excellence, Academic professions, Cross-country studies, Education

الوصف: Recruitment is one of the main strategic tools for universities, which aim to hire the best possible candidates for their academic positions. However, not every institution can hire whom they perceive as the best. Our paper investigates what are perceived to be the most pressing hindrances to attracting the best researchers. We focus on national and disciplinary differences in researchers’ perceptions of barriers to recruiting the best scholars in their fields. We surveyed researchers in economics and physics in the Netherlands, Norway, and the UK and find that economists emphasize salary level and institutional prestige as the main barriers, while physicists underline competition from non-academic actors and career development opportunities. We further find differences by country. In Norway, limited institutional prestige is a key barrier to attracting the best researchers, while researchers in the UK highlight salary levels. Respondents at Dutch universities claim that they experience multiple, equally important barriers.

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b35174ed20f895795a7e12f3ae43a294Test
https://hdl.handle.net/11250/3036321Test

المؤلفون: Silke Ohlmeier, Lara Schlomann, Holger Pfaff, Birthe A. Lehmann, Kyung-Eun Choi, Lara Lindert

المصدر: International Journal of Environmental Research and Public Health
Volume 17
Issue 6
International Journal of Environmental Research and Public Health, Vol 17, Iss 6, p 1886 (2020)

مصطلحات موضوعية: Randomization, Health, Toxicology and Mutagenesis, Best practice, Applied psychology, lcsh:Medicine, Intervention group, randomization, Article, law.invention, Random Allocation, 03 medical and health sciences, 0302 clinical medicine, Effective interventions, Randomized controlled trial, law, Humans, Multicenter Studies as Topic, 030212 general & internal medicine, Randomized Controlled Trials as Topic, Patient Selection, lcsh:R, Public Health, Environmental and Occupational Health, Focus Groups, Focus group, recruitment barriers, Health promotion, case managers, Psychology, RCT, qualitative research, 030217 neurology & neurosurgery, Qualitative research

الوصف: Background: Randomized controlled trials (RCTs) are regarded as the most internally valid means of estimating the effectiveness of complex public health interventions, but the recruitment of participants can be difficult. The aim of this study was to explore factors that may have affected the recruitment of employees with musculoskeletal disorders (MSDs) to a multicenter worksite health promotion program from the perspective of recruiting case managers. Methods: Factors in recruitment to the RCT were explored using three focus group discussions with case managers. Data were processed using MAXQDA and analyzed with a combination of content and sequence analysis. Results: Findings showed that randomization is a major challenge for recruitment. Case managers adapted their communication with, and approaches to possible participants because of the randomization design and employed coping strategies to compensate for allocation into the control arm of the study. Perceptions of the superiority of the intervention group over the control group, perceptions of the (mis)match of participants to one of the groups, as well as the understanding of the necessity of randomization for effectiveness evaluations, further affected recruitment. Perceived expectations of possible participants and their (emotional) reactions to the randomization allocation also complicated recruitment. Conclusion: We were able to gain insight into the challenges of randomization for the recruitment of participants to a multicenter RCT. This study assisted the development of strategies to overcome barriers in the ongoing implementation process of the trial (i.e., the adaption of best practice information sheets and newsletters). There remains a need to develop effective interventions to help those recruiting to trials.

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ca0fbc797fbac00099954251aae443Test
https://doi.org/10.3390/ijerph17061886Test

المؤلفون: Jegzentis, Kati

مصطلحات موضوعية: clinical trials, recruiting, IT algorithm, 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit, stroke, recruitment barriers

الوصف: Die Rekrutierungsphase ist ein entscheidender Abschnitt jeder klinischen Prüfung und bestimmt maßgeblich die Dauer einer Studie. Eine realistische Planung dieser zentralen Studienphase muss neben der laut Fallzahlplanung erforderlichen Teilnehmerzahl die erwartete Verfügbarkeit von Patienten bzw. Probanden berücksichtigen. Um die solchermaßen prognostizierten Rekrutierungsraten zu realisieren, ist eine möglichst vollständige Erfassung potentieller Studienteilnehmer in der Rekrutierungsphase von fundamentaler Bedeutung. Ziel der vorliegenden Dissertation ist die Charakterisierung der Zusammenhänge zwischen Selektionskriterien und der Patientenverfügbarkeit bzw. den daraus resultierenden Rekrutierungsraten sowie die Evaluierung von IT- Algorithmen, die das Auffinden potentiell geeigneter Studienteilnehmer unterstützen. Im Projekt BIAS wurden die Ursachen für die unerwarteten Rekrutierungsschwierigkeiten einer am Centrum für Schlaganfallforschung Berlin (CSB) durchgeführten Studie analysiert. Zu diesem Zweck wurden in einem intensivierten Screening die Gründe, die zum Nicht-Einschluss von Schlaganfallpatienten führten, erfasst. In der Studie konnte die Bedeutung des kumulativen Effektes der Selektionskriterien auf die Patientenverfügbarkeit gezeigt werden: unter Berücksichtigung aller Selektionskriterien waren weniger als fünf Prozent der Schlaganfallpatienten für die Studie geeignet. Die Ergebnisse legen nahe, dass Rekrutierungsprognosen, die kumulative Effekte nicht einbeziehen und die Selektionskriterien unabhängig voneinander betrachten, zu unrealistischen Rekrutierungserwartungen führen. Im Projekt STREAM wurde ein Algorithmus evaluiert, der einen zeitnahen, automatisierten SMS-Versand für jeden im Krankenhaus neu aufgenommenen Schlaganfallpatienten an die Studienärztin auslöste. Für den Algorithmus wurden ausschließlich Routinedaten aus dem Krankenhaus-Informationssystem verarbeitet, so dass keine zusätzliche Datenerhebung und –dokumentation notwendig war. In den Projektauswertungen erwies sich der Algorithmus als technisch stabil und gewährleistete eine nahezu vollständige Identifikation aller Schlaganfallpatienten und den anschließenden SMS-Versand. Für den Einsatz im Akutstudienbereich, speziell im Bereich der akuten Schlaganfallstudien, war der Algorithmus aufgrund der zeitlichen Verzögerung des SMS-Versandes von durchschnittlich 62 Minuten nach Aufnahme des Patienten im Krankenhaus nur bedingt geeignet. Die Anwendung des Algorithmus in weniger zeitkritischen Studien erscheint dagegen sinnvoll und machbar. Im Projekt Study Matcher wurde ein IT-Algorithmus untersucht, der aus einer Vielzahl an Schlaganfallstudien die für den jeweiligen Patienten passenden Studien automatisiert identifizierte und eine Studienvorschlagsliste erstellte. Auch dieser Algorithmus nutzte ausschließlich Routinedaten aus dem Krankenhaus- Informationssystem, wobei die Besonderheit darin lag, dass neben strukturierten Daten auch unstrukturiert vorliegende Informationen für die Auswertung aufbereitet und nutzbar gemacht wurden. Es konnte gezeigt werden, dass sich durch den Algorithmus der Aufwand für das manuelle Patientenscreening verringern lässt. Dennoch bleibt das manuelle Screening aufgrund unsicherer Faktoren oder unvollständiger Daten zumindest für den Bereich der Schlaganfallstudien bis auf weiteres unerlässlich.
The recruiting phase is a crucial part of a clinical trial und substantially determines the duration of the whole study. A realistic scheduling of this central phase has to take into consideration both the required number of patients as well as the potential availability of participants. The ability to identify all potential study participants is of utmost relevance to fulfil the intended recruiting rates. This thesis analyzed the relation between selection criteria, availability of patients and the resulting recruiting rates and evaluated IT-algorithms that support the identification of potential trial participants. The project BIAS examines a stroke trial that was conducted in the Center for Stroke Research Berlin (CSB) and encountered unexpected recruiting problems. To analyze complications in patient recruitment, an intensified screening was initiated and the reasons for trial non-inclusion were documented for all CSB stroke patients. The project demonstrates the strong cumulative effects of selection criteria, i.e. less than 5% of stroke patients are potential participants when the whole of the selection criteria are taken into account. The results show that recruiting prognoses that ignore possible cumulative effects and regard selection criteria as independent factors will lead to unrealistic expectations. The project STREAM evaluates an IT-algorithm that sent an automated text message to a study physician for every new stroke patient admitted to the hospital. The algorithm operates on routine data from the clinical information system. The analysis shows that the algorithm proved to be technically stable and ensured a nearly complete identification of stroke patients. The algorithm provides only a limited benefit for acute trials, especially acute stroke trials, because of an average delay of 62 minutes between admission to hospital and transmission of text message. The implementation of the algorithm in less time critical trials seems to be feasible. The project Study Matcher investigates an IT-algorithm that provides an automated matching of appropriate trials to a stroke patient based on routinely documented information. The strength of this algorithm was the semantic processing of unstructured data from the clinical information system into data ready for automated utilization. Results show that the manual screening effort for identification of trial participants can be reduced by automatic algorithms. Yet, for stroke studies, additional manual screening remains crucial mostly to account for uncertain or incomplete patient data.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d581e48b5ee108dd8e871772169442Test
https://refubium.fu-berlin.de/handle/fub188/412Test