نتائج البحث - "Receptor Muscarinic M2"

31

RE1-silencing transcription factor controls the acute-to-chronic neuropathic pain transition and Chrm2 receptor gene expression in primary sensory neurons

المؤلفون: Shao Rui Chen, Hong Chen, Hui Lin Pan, Jixiang Zhang

المصدر: Journal of Biological Chemistry. 293:19078-19091

مصطلحات موضوعية: Male, 0301 basic medicine, RE1-silencing transcription factor, Biochemistry, Rats, Sprague-Dawley, Gene Knockout Techniques, chemistry.chemical_compound, 0302 clinical medicine, Dorsal root ganglion, Ganglia, Spinal, Muscarine, Muscarinic acetylcholine receptor, Promoter Regions, Genetic, Mice, Knockout, Analgesics, biology, Chronic pain, Molecular Bases of Disease, Acute Pain, Sciatic Nerve, Up-Regulation, Posterior Horn Cells, medicine.anatomical_structure, Nociception, Neuropathic pain, Female, Chronic Pain, medicine.symptom, medicine.medical_specialty, Sensory Receptor Cells, Down-Regulation, 03 medical and health sciences, Internal medicine, medicine, Animals, Molecular Biology, Receptor, Muscarinic M2, business.industry, Cell Biology, Nerve injury, medicine.disease, Repressor Proteins, 030104 developmental biology, Endocrinology, nervous system, chemistry, biology.protein, Neuralgia, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60e7b6395370117a795fdfce7d6b4b75Test
https://doi.org/10.1074/jbc.ra118.005846Test

32

Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists

المصدر: Proceedings of the National Academy of Sciences of the United States of America, vol 115, iss 47
Liu, Hongtao; Hofmann, Josefa; Fish, Inbar; Schaake, Benjamin; Eitel, Katrin; Bartuschat, Amelie; et al.(2018). Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115(47), 12046-12050. doi: 10.1073/pnas.1813988115. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/7dq0974tTest
Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: 0301 basic medicine, crystal structure, drug design, 1.1 Normal biological development and functioning, Pulmonary disease, Muscarinic Antagonists, Crystallography, X-Ray, muscarinic receptor, 03 medical and health sciences, 0302 clinical medicine, Underpinning research, In vivo, MD Multidisciplinary, Muscarinic acetylcholine receptor, Humans, Amino Acid Sequence, G protein-coupled receptor, Single amino acid, Pharmacology, Receptor, Muscarinic M3, Receptor, Muscarinic M2, Crystallography, Multidisciplinary, Chemistry, Antagonist, subtype selectivity, Biological Sciences, Acetylcholine, 3. Good health, Molecular Docking Simulation, Muscarinic M3, 030104 developmental biology, Muscarinic M2, Membrane protein, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, X-Ray, Biophysics, Generic health relevance, Development of treatments and therapeutic interventions, Selectivity, Receptor

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e6552391e24497b235d3deddc51c2dTest
https://doi.org/10.1073/pnas.1813988115Test

33

Regulating nociceptive transmission by VGluT2-expressing spinal dorsal horn neurons

المؤلفون: Hui-Jie Ma, Walter N. Hittelman, Li Wang, Hong Chen, Hui Lin Pan, Shao Rui Chen

المصدر: Journal of Neurochemistry. 147:526-540

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eef83105ca9bee8e7f613548ca37131Test
https://doi.org/10.1111/jnc.14588Test

34

Inter- and intra-specific differences in muscarinic acetylcholine receptor expression in the neural pathways for vocal learning in songbirds

المؤلفون: Chihiro Mori, Kazuhiro Wada, Miguel Sánchez-Valpuesta, Norman C. Asogwa, Shin Hayase

المصدر: Journal of Comparative Neurology. 526:2856-2869

مصطلحات موضوعية: Male, 0301 basic medicine, Individuality, Deafness, Songbirds, RRID: AB_2629439, 0302 clinical medicine, Neural Pathways, Muscarinic acetylcholine receptor, Testosterone, RRID: SCR_004870, sensorimotor learning, General Neuroscience, vocal learning, Receptors, Muscarinic, RRID: AB_221544, RRID: SCR_014199, Intracellular signal transduction, behavior and behavior mechanisms, RRID: SCR_014438, Nidopallium, animal structures, RRID: SCR_002865, Biology, Real-Time Polymerase Chain Reaction, 03 medical and health sciences, Species Specificity, Neuroplasticity, Biological neural network, Animals, Learning, RRID: SCR_012988, Acetylcholine receptor, Brain Chemistry, Receptor, Muscarinic M2, muscarinic receptors, Receptor, Muscarinic M1, RRID: AB_10821150, RRID: SCR_005780, biology.organism_classification, RRID: SCR_006356, songbird, acetylcholine, Songbird, individual variability, 030104 developmental biology, nervous system, Vocal learning, Finches, Vocalization, Animal, Neuroscience, 030217 neurology & neurosurgery

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a65870e5737134698c41b30a2540f6bTest
https://doi.org/10.1002/cne.24532Test

35

Impaired object-location learning and recognition memory but enhanced sustained attention in M2 muscarinic receptor-deficient mice

المؤلفون: Timothy J. Bussey, Lisa M. Saksida, Susan J. Bartko, Carola Romberg, Jürgen Wess

المصدر: Psychopharmacology
Brain and Mind Institute Researchers' Publications

مصطلحات موضوعية: Male, 0301 basic medicine, Paired-associates learning, Mice, 129 Strain, M2, Neurotransmission, Mice, 03 medical and health sciences, 0302 clinical medicine, Memory, Muscarinic, Muscarinic acetylcholine receptor, medicine, Psychology, Learning, Animals, Attention, Original Investigation, Recognition memory, Acetylcholine receptor, Mice, Knockout, Pharmacology, Receptor, Muscarinic M2, Neurosciences, Flexibility (personality), Recognition, Psychology, Cognition, Acetylcholine, Associative learning, Mice, Inbred C57BL, Recognition, 030104 developmental biology, Visual Perception, Conditioning, Operant, Neuroscience, Photic Stimulation, 030217 neurology & neurosurgery, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4141e4576f4ab200a283beeabf74354dTest
https://doi.org/10.1007/s00213-018-5065-7Test

36

I-Tiao-Gung extract through its active component daidzin improves cyclophosphamide-induced bladder dysfunction in rat model

المؤلفون: Chiang Ting Chien, Wen Hsin Tsai, Shiu Dong Chung, Kung Chieh Wu, Bing Juin Chiang

المصدر: Neurourology and Urodynamics. 37:2560-2570

مصطلحات موضوعية: Cyclophosphamide, Urology, Urinary Bladder, 030232 urology & nephrology, Urination, Pharmacology, urologic and male genital diseases, digestive system, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Urethra, Western blot, Cystitis, Muscarinic acetylcholine receptor, medicine, Animals, heterocyclic compounds, Rats, Wistar, Daidzin, Receptor, Muscarinic M3, Receptor, Muscarinic M2, medicine.diagnostic_test, Electromyography, Receptors, Purinergic P2, Urinary Bladder, Overactive, business.industry, Purinergic receptor, Daidzein, Muscarinic acetylcholine receptor M3, respiratory system, medicine.disease, Isoflavones, Rats, enzymes and coenzymes (carbohydrates), chemistry, 030220 oncology & carcinogenesis, Female, Neurology (clinical), business, Drugs, Chinese Herbal, Hemorrhagic cystitis, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::219a959aa5e336e8459c6a4019e5a866Test
https://doi.org/10.1002/nau.23815Test

37

Activation of M2 muscarinic acetylcholine receptors by a hybrid agonist enhances cytotoxic effects in GB7 glioblastoma cancer stem cells

المؤلفون: Luciano Conti, Mario Fiore, Marco De Amici, Ada Maria Tata, Ilaria Cristofaro, Clelia Dallanoce, Zaira Spinello, Carlo Matera

المصدر: Neurochemistry international 118 (2018): 52–60. doi:10.1016/j.neuint.2018.04.010
info:cnr-pdr/source/autori:Cristofaro I.; Spinello Z.; Matera C.; Fiore M.; Conti L.; De Amici M.; Dallanoce C.; Tata A.M./titolo:Activation of M2 muscarinic acetylcholine receptors by a hybrid agonist enhances cytotoxic effects in GB7 glioblastoma cancer stem cells/doi:10.1016%2Fj.neuint.2018.04.010/rivista:Neurochemistry international/anno:2018/pagina_da:52/pagina_a:60/intervallo_pagine:52–60/volume:118

مصطلحات موضوعية: Cell death, 0301 basic medicine, Agonist, Cancer stem cells Cell death M2 muscarinic acetylcholine receptors Dualsteric (allosteric/orthosteric) activators DNA damage, Cell Survival, medicine.drug_class, Muscarinic Agonists, Pharmacology, Muscarinic agonist, 03 medical and health sciences, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Cell Line, Tumor, Muscarinic acetylcholine receptor, medicine, Methoctramine, Humans, Cytotoxic T cell, Receptor, Receptor, Muscarinic M2, Dose-Response Relationship, Drug, Cancer stem cells, Dualsteric (allosteric/orthosteric) activators, Cell growth, Chemistry, Muscarinic acetylcholine receptor M2, Cell Biology, M2 muscarinic acetylcholine receptors, 030104 developmental biology, Neoplastic Stem Cells, DNA damage, Glioblastoma