المؤلفون: Manimegalai, B.¹, Swarnalatha, GV², Ramanathan, Veerappan¹, Rajagopal, Senthilkumar^{3, 1}

المصدر: Current Trends in Biotechnology and Pharmacy 15(4):361-367. 2021

المؤلفون: Ramanathan, Veerappan¹, Swarnalatha, GV², Manimegalai, B.¹, amalraj, A. Dominic¹, Rajagopal, Senthilkumar^{2, 1}

المصدر: CURRENT TRENDS IN BIOTECHNOLOGY AND PHARMACY 14(3):327-339. 2020

المؤلفون: Anand, Santosh, Rajagopal, Senthilkumar

المصدر: Neuroscience Insights ; volume 18 ; ISSN 2633-1055 2633-1055

الوصف: The transient receptor potential (TRP) superfamily of ion channels in humans comprises voltage-gated, non-selective cation channels expressed both in excitable as well as non-excitable cells. Four TRP channel subunits associate to create functional homo- or heterotetramers that allow the influx of calcium, sodium, and/or potassium. These channels are highly abundant in the brain and kidney and are important mediators of diverse biological functions including thermosensation, vascular tone, flow sensing in the kidney and irritant stimuli sensing. Inherited or acquired dysfunction of TRP channels influences cellular functions and signaling pathways resulting in multifaceted disorders affecting skeletal, renal, cardiovascular, and nervous systems. Studies have demonstrated the involvement of these channels in the generation and transduction of pain. Based on the multifaceted role orchestrated by these TRP channels, modulation of the activity of these channels presents an important strategy to influence cellular function by regulating intracellular calcium levels as well as membrane excitability. Therefore, there has been a remarkable pharmaceutical inclination toward TRP channels as therapeutic interventions. Several candidate drugs influencing the activity of these channels are already in the clinical trials pipeline. The present review encompasses the current understanding of TRP channels and TRP modulators in pain and pain management.

الإتاحة: https://doi.org/10.1177/26331055231220340Test

المؤلفون: Vidya, Murugasen, Rajagopal, Senthilkumar

المصدر: Recent Developments in Nanomaterial-based Sensing of Human Pathogens ; page 269-279 ; ISBN 9780443185748

الإتاحة: https://doi.org/10.1016/b978-0-443-18574-8.00016-9Test
https://api.elsevier.com/content/article/PII:B9780443185748000169?httpAccept=text/xmlTest
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المؤلفون: Ankireddy, Seshadri Reddy, Babu, Yangala Sudheer, Buddolla, Viswanath, Chappidi, Sindhuspoorthy, Chendruru, Geya Sree, Chintapalli, Indhravathi, Devi, Palempalli Uma Maheswari, Gunavathi, Yanamala, Jivin, Bangarupeta Murali Manpreet, Jyotshna, S., Kameswaran, Srinivasan, Kandati, Kusuma, Kashyap, Merry, Kilaru, Meghana, Kishore, Kamal, Kopparthi, Jalajakshi, Kumari, Neetu, Laxmi, Bugude, Maruthi, Mulaka, Mishra, Prabhakar, Muralidaran, Yuvashree, Nannepaga, John Sushma, Oruganti, Srividya, Pitchika, Gopi Krishna, Radhakrishnan, Akshar, Rajagopal, Senthilkumar, Ramesh, Bellemkonda, Ranjani, T. Sri, Rao, Yagani Jayavardhana, Rayi, Ramesh, Sagar, Annapoorni Lakshman, Singh, Manpreet, Sinharay, Amrita, Thanjavur, Naveen, Umapathi, Rekha, Usha, Rayalcheruvu, Vidya, Murugasen

المصدر: Recent Developments in Nanomaterial-based Sensing of Human Pathogens ; page xvii-xix ; ISBN 9780443185748

الإتاحة: https://doi.org/10.1016/b978-0-443-18574-8.00019-4Test
https://api.elsevier.com/content/article/PII:B9780443185748000194?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:B9780443185748000194?httpAccept=text/plainTest

المؤلفون: Radhakrishnan, Akshar, Kashyap, Merry, Sinharay, Amrita, Jyotshna, S., Rajagopal, Senthilkumar

المصدر: Recent Developments in Nanomaterial-based Sensing of Human Pathogens ; page 93-113 ; ISBN 9780443185748

الإتاحة: https://doi.org/10.1016/b978-0-443-18574-8.00006-6Test
https://api.elsevier.com/content/article/PII:B9780443185748000066?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:B9780443185748000066?httpAccept=text/plainTest

المؤلفون: Mishra, Prabhakar, Muralidaran, Yuvashree, Rajagopal, Senthilkumar

المصدر: Recent Developments in Nanomaterial-based Sensing of Human Pathogens ; page 185-201 ; ISBN 9780443185748

الإتاحة: https://doi.org/10.1016/b978-0-443-18574-8.00007-8Test
https://api.elsevier.com/content/article/PII:B9780443185748000078?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:B9780443185748000078?httpAccept=text/plainTest

المؤلفون: Ahmad, Sarfraz, Anil Kumar, Meghavarnam, Aruna, Varimadugu, Bajpai, Richa, Bandapalli, Obul Reddy, Behera, Abhayananda, Behera, Lambodar, Bhaskar, L.V.K.S., Daka, Gopamma, Dariya, Begum, Dasari, Kalyani, Donde, Ravindra, Ganguli, Debayan, Girish, Bala Prabhakar, Gouda, Gayatri, Gowda, Cheemachanahalli Muninanjappa Mohan, Gowda, Nirmala Gollarahalli Sannappa, Gupta, Manoj Kumar, Harshitha, D. Sai, Imran, Mohammad, Jinka, Rajeswari, Kadiri, Deepika Divya, Kaladhar, Dowluru S.V.G.K., Kalam, Sirisha, Kodidela, Swarnalatha, Kumari, Seema, Madduru, Dhatri, Malla, Rama Rao, Mandala, Jyothi Priya, Mehta, Arundhati, Merchant, Neha, Murugesan, Vidya, Nagaraju, Ganji Purnachandra, Namuduri, Srinivas, Pangi, Vijaya Nirmala, Pappu, Pranathi, Peela, Sujatha, Podeti, Srinivas, Porika, Mahendar, Rajagopal, Senthilkumar, Rakshit, Samrat, Rao Kakarla, Jagadeeswara, Rashid, Mamoon Ur., Ratre, Yashwant Kumar, Reddy, Aramati Bindu Madhava, Sahu, Nisha, Santhekadur, Prasanna Kumar, Sarvepalli, Deepika, Sharma, Rajesh, Shiragannavar, Varsha Dilip

المصدر: Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma ; page xv-xvii

الإتاحة: https://doi.org/10.1016/b978-0-323-98806-3.00029-5Test
https://api.elsevier.com/content/article/PII:B9780323988063000295?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:B9780323988063000295?httpAccept=text/plainTest

المؤلفون: Padmanaban Ajay, Venkataraman Ramesh, Rajagopal Senthilkumar, Devaprasad Dedeepiya, Ramakrishnan Nagarajan

المصدر: The Journal of Critical Care Medicine, Vol 6, Iss 4, Pp 210-216 (2020)

مصطلحات موضوعية: vasopressors, central venous catheter, peripheral venous catheter, hemodynamic emergencies, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

الوصف: Vasopressors are conventionally administered through a central venous catheter (CVC) and not through a peripheral venous catheter (PVC) since the latter is believed to be associated with increased risk of extravasation. Placement of a CVC requires suitably trained personnel to be on hand, and in resource-limited settings, this requirement may delay placement. Because of this and in cases where suitably trained personnel are not immediately available, some clinicians may be prompted to utilise a PVC for infusing vasopressors. The objective of this study is to assess the feasibility and safety of vasopressors administered through a PVC.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2393-1817Test

الوصول الحر: https://doaj.org/article/a6bd37edb8f74f8e9a8e29a2eede8297Test

المؤلفون: Rajagopal, Senthilkumar, Kumar, Divya P., Arul, Albert Baskar

المصدر: Frontiers in Cellular Neuroscience ; volume 16 ; ISSN 1662-5102

مصطلحات موضوعية: Cellular and Molecular Neuroscience

الإتاحة: https://doi.org/10.3389/fncel.2022.928457Test