المؤلفون: Rahmioglu, N, Mortlock, S, Ghiasi, M, Møller, PL, Stefansdottir, L, Galarneau, G, Turman, C, Danning, R, Law, MH, Sapkota, Y, Christofidou, P, Skarp, S, Giri, A, Banasik, K, Krassowski, M, Lepamets, M, Marciniak, B, Nõukas, M, Perro, D, Sliz, E, Sobalska-Kwapis, M, Thorleifsson, G, Topbas-Selcuki, NF, Vitonis, A, Westergaard, D, Arnadottir, R, Burgdorf, KS, Campbell, A, Cheuk, CSK, Clementi, C, Cook, J, De Vivo, I, DiVasta, A, Dorien, O, Donoghue, JF, Edwards, T, Fontanillas, P, Fung, JN, Geirsson, RT, Girling, JE, Harkki, P, Harris, HR, Healey, M, Heikinheimo, O, Holdsworth-Carson, S, Hostettler, IC, Houlden, H, Houshdaran, S, Irwin, JC, Jarvelin, MR, Kamatani, Y, Kennedy, SH, Kepka, E, Kettunen, J, Kubo, M, Kulig, B, Kurra, V, Laivuori, H, Laufer, MR, Lindgren, CM, MacGregor, S, Mangino, M, Martin, NG, Matalliotaki, C, Matalliotakis, M, Murray, AD, Ndungu, A, Nezhat, C, Olsen, CM, Opoku-Anane, J, Padmanabhan, S, Paranjpe, M, Peters, M, Polak, G, Porteous, DJ, Rabban, J, Rexrode, KM, Romanowicz, H, Saare, M, Saavalainen, L, Schork, AJ, Sen, S, Shafrir, AL, Siewierska-Górska, A, Słomka, M, Smith, BH, Smolarz, B, Szaflik, T, Szyłło, K, Takahashi, A, Terry, KL, Tomassetti, C, Treloar, SA, Vanhie, A, Vincent, K, Vo, KC, Werring, DJ, Zeggini, E, Zervou, MI, Adachi, S, Buring, JE, Ridker, PM, D'Hooghe, T, Goulielmos, GN, Hapangama, DK, Hayward, C, Horne, AW, Low, SK, Martikainen, H, Chasman, DI, Rogers, PAW, Saunders, PT, Sirota, M, Spector, T, Strapagiel, D, Tung, JY, Whiteman, DC, Giudice, LC, Velez-Edwards, DR, Uimari, O, Kraft, P, Salumets, A, Nyholt, DR, Mägi, R, Stefansson, K, Becker, CM, Yurttas-Beim, P, Steinthorsdottir, V, Nyegaard, M, Missmer, SA, Montgomery, GW, Morris, AP, Zondervan, KT

المصدر: Nature genetics. 55(3):423-436

مصطلحات موضوعية: Medicin och hälsovetenskap

الوصول الحر: http://kipublications.ki.se/Default.aspx?queryparsed=id:236914876Test

المؤلفون: Sliz, E, Tyrmi, JS, Rahmioglu, N, Zondervan, KT, Becker, CM, Uimari, O, Kettunen, J, Palotie, A, Daly, M, Riley-Gills, B, Jacob, H, Paul, D, Matakidou, A, Platt, A, Runz, H, John, S, Okafo, G, Lawless, N, Salminen-Mankonen, H, Plenge, R, Maranville, J, McCarthy, M, Ehm, MG, Auro, K, Longerich, S, Fox, C, Malarstig, A, Klinger, K, Chatelain, C, Gossel, M, Estrada, K, Graham, R, Yang, R, O'Donnell, C, Makela, TP, Kaprio, J, Virolainen, P, Hakanen, A, Kilpi, T, Perola, M, Partanen, J, Pitkaranta, A, Raivio, T, Serpi, R, Laitinen, T, Kosma, VM, Laukkanen, J, Hautalahti, M, Tuovila, O, Pakkanen, R, Waring, J, Riley-Gillis, B, Rahimov, F, Tachmazidou, I, Chen, CY, Ding, ZH, Jung, M, Biswas, S, Pendergrass, R, Pulford, D, Raghavan, N, Huertas-Vazquez, A, Sul, JH, Hu, XL, Hedman, A, Rivas, M, Waterworth, D, Renaud, N, Obeidat, M, Ripatti, S, Schleutker, J, Arvas, M, Carpen, O, Hinttala, R, Mannermaa, A, Aalto-Setala, K, Kahonen, M, Makela, J, Kalviainen, R, Julkunen, V, Soininen, H, Remes, A, Hiltunen, M, Peltola, J, Raivio, M, Tienari, P, Rinne, J, Kallionpaa, R, Abbasi, A, Ziemann, A, Smaoui, N, Lehtonen, A, Eaton, S, Lahdenpera, S, Bowers, N, Teng, E, Xu, FL, Addis, L, Eicher, J, Li, QQS, He, K, Khramtsova, E, Farkkila, M, Koskela, J, Pikkarainen, S, Jussila, A, Kaukinen, K, Blomster, T, Kiviniemi, M, Voutilainen, M, Lu, T, McCarthy, L, Hart, A, Guan, MJ, Miller, J, Kalpala, K, Miller, M, Eklund, K, Palomaki, A, Isomaki, P, Pirila, L, Kaipiainen-Seppanen, O, Huhtakangas, J, Mars, N, Lertratanakul, A, Hochfeld, M, Gordillo, JE, Farias, F, Bing, N, Pelkonen, M, Kauppi, P, Kankaanranta, H, Harju, T, Lahesmaa, R, Lassi, G, Chen, H, Betts, J, Mishra, R, Mouded, M, Ngo, D, Niiranen, T, Vaura, F, Salomaa, V, Metsarinne, K, Aittokallio, J, Hernesniemi, J, Gordin, D, Sinisalo, J, Taskinen, MR, Tuomi, T, Hiltunen, T, Elliott, A, Reeve, MP, Ruotsalainen, S, Challis, B, Chu, A, Reilly, D, Mendelson, M, Parkkinen, J, Meretoja, T, Joensuu, H, Mattson, J, Salminen, E, Auranen, A, Karihtala, P, Auvinen, P, Elenius, K, Pitkanen, E, Popovic, R, Schutzman, J, Kulkarni, D, Porello, A, Loboda, A, Lehtonen, H, McDonough, S, Vuoti, S, Kaarniranta, K, Turunen, JA, Ollila, T, Uusitalo, H, Karjalainen, J, Liu, MZ, Loomis, S, Strauss, E, Tasanen, K, Huilaja, L, Hannula-Jouppi, K, Salmi, T, Peltonen, S, Koulu, L, Choy, D, Wu, Y, Pussinen, P, Salminen, A, Salo, T, Rice, D, Nieminen, P, Palotie, U, Siponen, M, Suominen, L, Mantyla, P, Gursoy, U, Anttonen, V, Sipila, K, Laivuori, H, Kurra, V, Kotaniemi-Talonen, L, Heikinheimo, O, Kalliala, I, Aaltonen, L, Jokimaa, V, Vaarasmaki, M, Morin-Papunen, L, Niinimaki, M, Piltonen, T, Kivinen, K, Widen, E, Tukiainen, T, Valimaki, N, Laakkonen, E, Silven, H, Arffman, R, Savukoski, S, Laisk, T, Pujol, N, Kumar, J, Hovatta, I, Isometsa, E, Ollila, H, Suvisaari, J, Als, TD, Makitie, A, Bizaki-Vallaskangas, A, Toppila-Salmi, S, Willberg, T, Saarentaus, E, Aarnisalo, A, Rahikkala, E, Aittomaki, K, Aberg, F, Kurki, M, Havulinna, A, Mehtonen, J, Palta, P, Hassan, S, Parolo, PD, Zhou, W, Maasha, M, Lemmela, S, Liu, AX, Lehisto, A, Ganna, A, Llorens, V, Heyne, H, Ramo, J, Rodosthenous, R, Strausz, S, Palotie, T, Palin, K, Garcia-Tabuenca, J, Siirtola, H, Kiiskinen, T, Lee, J, Tsuo, K, Kristiansson, K, Hyvarinen, K, Ritari, J, Pylkas, K, Karjalainen, M, Mantere, T, Kangasniemi, E, Heikkinen, S, Pitkanen, N, Lessard, S, Terho, P, Wahlfors, T, Punkka, E, Siltanen, S, Kuopio, T, Jalanko, A, Shen, HY, Kajanne, R, Aavikko, M, Palin, H, Linna, MM, Kanai, M, Zheng, ZL, Lahtela, LE, Kaunisto, M, Kilpelainen, E, Sipila, TP, Dada, OA, Ghazal, A, Kytola, A, Weldatsadik, R, Donner, K, Loukola, A, Laiho, P, Sistonen, T, Kaiharju, E, Laukkanen, M, Jarvensivu, E, Lahteenmaki, S, Mannikko, L, Wong, R, Toivola, A, Brunfeldt, M, Mattsson, H, Koskelainen, S, Hiekkalinna, T, Paajanen, T, Parn, K, Kals, M, Luo, S, Padmanabhuni, SS, Niemi, M, Gracia-Tabuenca, J, Helminen, M, Luukkaala, T, Vahatalo, I, Tammerluoto, J, Smith, S, Southerington, T, Lehto, P

المصدر: Nature communications. 14(1):542

مصطلحات موضوعية: Medicin och hälsovetenskap

الوصول الحر: http://kipublications.ki.se/Default.aspx?queryparsed=id:153370600Test

المؤلفون: Rahmioglu, N, Macgregor, S, Drong, AW, Hedman, AK, Harris, HR, Randall, JC, Prokopenko, I, Nyholt, DR, Morris, AP, Montgomery, GW, Missmer, SA, Lindgren, CM, Zondervan, KT

المصدر: Human molecular genetics. 24(4):1185-1199

مصطلحات موضوعية: Medicin och hälsovetenskap

الوصول الحر: http://kipublications.ki.se/Default.aspx?queryparsed=id:130808571Test

المؤلفون: Demetriou, L, Krassowski, M, Abreu Mendes, P, Garbutt, K, Vitonis, AF, Wilkins, E, Coxon, L, Arendt-Nielsen, L, Aziz, Q, Birch, J, Horne, AW, Hoffman, A, Hummelshoj, L, Lunde, CE, Meijlink, J, Perro, D, Rahmioglu, N, Terry, KL, Pogatzki-Zahn, E, Sieberg, CB, Treede, R-D, Becker, CM, Cruz, F, Missmer, SA, Zondervan, KT, Nagel, J, Vincent, K

الوصف: Introduction: Chronic pelvic pain (CPP) is a common condition affecting up to 26.6% of women, with many suffering for several years before diagnosis and/or treatment. Its clinical presentation is varied and there are frequently comorbid conditions both within and outside the pelvis. We aim to explore whether specific subgroups of women with CPP report different clinical symptoms and differing impact of pain on their quality of life (QoL). Methods: The study is part of the Translational Research in Pelvic Pain (TRiPP) project which is a cross-sectional observational cohort study. The study includes 769 female participants of reproductive age who completed an extensive set of questions derived from standardised WERF EPHect questionnaires. Within this population we defined a control group (reporting no pelvic pain, no bladder pain syndrome, and no endometriosis diagnosis, N = 230) and four pain groups: endometriosis-associated pain (EAP, N = 237), interstitial cystitis/bladder pain syndrome (BPS, N = 72), comorbid endometriosis-associated pain and BPS (EABP, N = 120), and pelvic pain only (PP, N = 127). Results: Clinical profiles of women with CPP (13–50 years old) show variability of clinical symptoms. The EAP and EABP groups scored higher than the PP group (p p p p p p p Discussion: Our results demonstrate the negative impact that chronic pain has on CPP patients' QoL and reveal an increased negative impact of pain on the comorbid EABP group. Furthermore, it demonstrates the importance of dyspareunia in women with CPP. Overall, our results demonstrate the need for further exploration of interventions targeting QoL more broadly and suggest that novel approaches to classifying women with CPP are needed.

العلاقة: https://ora.ox.ac.uk/objects/uuid:e4410b1d-b04b-4497-8c28-3d01ad38605dTest; https://doi.org/10.3389/frph.2023.1140857Test

الإتاحة: https://doi.org/10.3389/frph.2023.1140857Test
https://ora.ox.ac.uk/objects/uuid:e4410b1d-b04b-4497-8c28-3d01ad38605dTest

المؤلفون: Swift, B., Naci, H., Taneri, B., Becker, C. M., Zondervan, K. T., Rahmioglu, N.

مصطلحات موضوعية: RA0421 Public health. Hygiene. Preventive Medicine, HQ The family. Marriage. Woman

الوصف: Purpose: Describe the health-related quality of life for a representative cohort of women aged 18–55 in Northern Cyprus. Methods: We utilised the SF-36-Health-Survey-version-2 (SF-36v2) questionnaire as part of the COHERE Initiative study to calculate the eight physical and mental subscale scores, as well as the two overall summary measures for physical and mental health, where we present results using Cyprus-specific scoring as well as scores based on the test developers’ algorithms. We examined associations between sociodemographic characteristics for both scores. Results: A total of 7089 women fully completed the SF-36v2 questionnaire (mean age = 36.9), which was reliable and valid in this population. We observed better physical health in ages 18–25 compared to 46–55 (53.32 vs. 46.72 (p < 0.001)) and better mental health in women aged 46–55 compared to 18–25 (52.07 vs. 47.95 (p < 0.001)). Women in employment had better physical and mental health compared to those who were unemployed (physical: 50.25 vs 49.95, p < 0.001 and mental: 50.25 vs 49.24, p = 0.083) and scores increased as educational attainment increased (physical: 47.55 for primary to 51.58 for postgraduate, mental: 48.88 to 50.59, p < 0.001). Turkish Cypriot women had higher scores than Turkish women (physical: 50.42 vs 49.30, mental: 50.43 vs 49.10, p < 0.001). Conclusion: These are the first population normative values published from a large representative sample of women between 18 and 55 years from the Eastern Mediterranean region. We found better physical health in younger women and better mental health in older women. Turkish Cypriot women and non-migrant women had better mental health, and HRQOL was highest in those in paid employment and those with a higher educational achievement.

وصف الملف: text

العلاقة: http://eprints.lse.ac.uk/113921/1/Swift2022_Article_TheCyprusWomenSHealthResearchC.pdfTest; Swift, B., Naci, H., Taneri, B., Becker, C. M., Zondervan, K. T. and Rahmioglu, N. (2022) The Cyprus Women’s Health Research (COHERE) initiative: normative data from the SF-36v2 questionnaire for reproductive aged women from the Eastern Mediterranean. Quality of Life Research, 31 (7). 2011 - 2022. ISSN 0962-9343

الإتاحة: http://eprints.lse.ac.uk/113921Test/
http://eprints.lse.ac.uk/113921/1/Swift2022_Article_TheCyprusWomenSHealthResearchC.pdfTest
https://link.springer.com/journal/11136Test

المؤلفون: Gallagher, C. S., Mäkinen, N., Harris, H. R., Rahmioglu, N., Uimari, O., Cook, J. P., Shigesi, N., Ferreira, T., Velez-Edwards, D. R., Edwards, T. L., Mortlock, S., Ruhioglu, Z., Day, F., Becker, C. M., Karhunen, V., Martikainen, H., Järvelin, M.-R., Cantor, R. M., Ridker, P. M., Terry, K. L., Buring, J. E., Gordon, S. D., Medland, S. E., Montgomery, G. W., Nyholt, D. R., Hinds, D. A., Tung, J. Y., Agee, Michelle, Alipanahi, Babak, Auton, Adam, Bell, Robert K., Bryc, Katarzyna, Elson, Sarah L., Fontanillas, Pierre, Furlotte, Nicholas A., Huber, Karen E., Kleinman, Aaron, Litterman, Nadia K., McIntyre, Matthew H., Mountain, Joanna L., Noblin, Elizabeth S., Northover, Carrie A. M., Pitts, Steven J., Sathirapongsasuti, J. Fah, Sazonova, Olga V., Shelton, Janie F., Shringarpure, Suyash, Tian, Chao, Vacic, Vladimir, Wilson, Catherine H.

المصدر: Nature Communications ; volume 13, issue 1 ; ISSN 2041-1723

مصطلحات موضوعية: General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Multidisciplinary

الإتاحة: https://doi.org/10.1038/s41467-022-33222-yTest
https://www.nature.com/articles/s41467-022-33222-y.pdfTest
https://www.nature.com/articles/s41467-022-33222-yTest

المؤلفون: Saare, M, Krigul, KL, Laisk-Podar, T, Ponandai-Srinivasan, S, Rahmioglu, N, Kumar, PGL, Zondervan, K, Salumets, A, Peters, M

المصدر: Biology of reproduction. 99(2):273-282

مصطلحات موضوعية: Medicin och hälsovetenskap

الوصول الحر: http://kipublications.ki.se/Default.aspx?queryparsed=id:139328645Test

المؤلفون: Giudice, Linda, Vitonis, AF, Vincent, K, Rahmioglu, N, Fassbender, A, Buck, GM, Hummelshoj, L, Giudice, LC, Stratton, P, Adamson, GD, Becker, CM

الوصف: ©2014 by American Society for Reproductive Medicine.Objective: To harmonize the collection of nonsurgical clinical and epidemiologic data relevant to endometriosis research, allowing large-scale collaboration. Design: An international collaboration involvi

الوصول الحر: https://escholarship.org/uc/item/8ks2k519Test

المؤلفون: Giudice, Linda, Fassbender, A, Rahmioglu, N, Vitonis, AF, Viganò, P, Giudice, LC, D'Hooghe, TM, Hummelshoj, L, David, G, Becker, CM, Missmer, SA

الوصف: ©2014 by American Society for Reproductive Medicine.Objective: To harmonize standard operating procedures (SOPs) and standardize the recording of associated data for collection, processing, and storage of human tissues relevant to endometriosis. Design: An

الوصول الحر: https://escholarship.org/uc/item/37z5w768Test

المؤلفون: Giudice, Linda, Rahmioglu, N, Fassbender, A, Vitonis, AF, Tworoger, SS, Hummelshoj, L, D'Hooghe, TM, Adamson, GD, Giudice, LC, Becker, CM, Zondervan, KT

الوصف: ©2014 by American Society for Reproductive Medicine.Objective: To harmonize standard operating procedures (SOPs) and standardize the recording of associated data for collection, processing, and storage of fluid biospecimens relevant to endometriosis. Desig

الوصول الحر: https://escholarship.org/uc/item/3gw0x6z7Test