المؤلفون: R. Charlotte Moffett, Srividya Vasu, Peter R. Flatt

المصدر: Biochimica et Biophysica Acta (BBA) - General Subjects. 1850:1206-1214

مصطلحات موضوعية: Blood Glucose, Male, endocrine system, medicine.medical_specialty, Time Factors, Normal diet, Biophysics, Incretin, Apoptosis, Gastric Inhibitory Polypeptide, Biology, Diet, High-Fat, Biochemistry, Glucagon, Alpha cell, Receptors, Gastrointestinal Hormone, Islets of Langerhans, Insulin resistance, Glucagon-Like Peptide 1, Internal medicine, medicine, Animals, Insulin, Glucose homeostasis, Intestinal Mucosa, Molecular Biology, Adiposity, Cell Proliferation, Mice, Knockout, geography, geography.geographical_feature_category, medicine.disease, Islet, Adaptation, Physiological, Mice, Inbred C57BL, Endocrinology, Insulin Resistance, Beta cell, hormones, hormone substitutes, and hormone antagonists

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d32e0ba188845918b5e0a3dd7c810fTest
https://doi.org/10.1016/j.bbagen.2015.02.006Test

المؤلفون: Srividya Vasu, Opeolu O. Ojo, Peter R. Flatt, Yasser Abdel-Wahab, J. Michael Conlon, R. Charlotte Moffett

المصدر: Amino acids. 49(10)

مصطلحات موضوعية: 0301 basic medicine, Male, endocrine system, medicine.medical_specialty, medicine.medical_treatment, Clinical Biochemistry, 030209 endocrinology & metabolism, Type 2 diabetes, Biology, Biochemistry, Glucagon, Alpha cell, Amphibian Proteins, Diabetes Mellitus, Experimental, Impaired glucose tolerance, 03 medical and health sciences, Mice, 0302 clinical medicine, Insulin resistance, Diabetes mellitus, Internal medicine, medicine, Animals, Hypoglycemic Agents, Insulin, Obesity, Organic Chemistry, Cholesterol, LDL, medicine.disease, Dietary Fats, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, Liver function, Insulin Resistance, Antimicrobial Cationic Peptides

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230518b1d073276fb34a6d023bd4e596Test
https://pubmed.ncbi.nlm.nih.gov/28836148Test

المؤلفون: Peter R. Flatt, Yasser Abdel-Wahab, Mary K. McGahon, Tim M. Curtis, J. Michael Conlon, Srividya Vasu, R. Charlotte Moffett

المصدر: Vasu, S, McGahon, M K, Moffett, R C, Curtis, T M, Conlon, J M, Abdel-Wahab, Y H A & Flatt, P R 2017, ' Esculentin-2CHa(1–30) and its analogues: stability and mechanisms of insulinotropic action ', The Journal of endocrinology, vol. 232, pp. 423-435 . https://doi.org/10.1530/JOE-16-0453Test

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Biology, Cyclase, Cell Line, Membrane Potentials, 03 medical and health sciences, Mice, Endocrinology, SDG 3 - Good Health and Well-being, Internal medicine, Insulin-Secreting Cells, Insulin Secretion, medicine, Diazoxide, Cyclic AMP, Animals, Humans, Insulin, Glycosides, Protein kinase C, Membrane potential, Phospholipase C, Biological activity, 030104 developmental biology, Biochemistry, Pregnenolone, Calcium, Intracellular, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542321c93e5192dd3e645bad959c61f7Test
https://pure.qub.ac.uk/en/publications/esculentin2cha130-and-its-analogues-stability-and-mechanisms-of-insulinotropic-actionTest(1bd9c64b-c8d3-4670-9664-c64322512baa).html

المؤلفون: Peter R. Flatt, J. Michael Conlon, Yasser Abdel-Wahab, Vishal Musale, Bosede O. Owolabi, R. Charlotte Moffett, Mary K. McGahon, Tim M. Curtis, Opeolu O. Ojo

المصدر: Owolabi, B O, Musale, V, Ojo, O O, Moffett, R C, McGahon, M K, Curtis, T M, Conlon, J M, Flatt, P R & Abdel-Wahab, Y H A 2017, ' Actions of PGLa-AM1 and its [A14K] and [A20K] analogues and their therapeutic potential as anti-diabetic agents ', Biochimie, vol. 138, pp. 1-12 . https://doi.org/10.1016/j.biochi.2017.04.004Test

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Pipidae, medicine.medical_treatment, Down-Regulation, 030209 endocrinology & metabolism, Peptide, Stimulation, Xenopus Proteins, Biochemistry, Amphibian Proteins, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Insulin resistance, Internal medicine, Insulin-Secreting Cells, Insulin Secretion, Journal Article, medicine, Animals, Humans, Hypoglycemic Agents, Insulin, Protein kinase A, chemistry.chemical_classification, Forskolin, biology, General Medicine, biology.organism_classification, medicine.disease, Cyclic AMP-Dependent Protein Kinases, Rats, 030104 developmental biology, Endocrinology, chemistry, Apoptosis, Calcium, Antimicrobial Cationic Peptides, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79a59fe8f2a0627bf19125adb50b34aTest
https://pubmed.ncbi.nlm.nih.gov/28392407Test

المؤلفون: Peter R. Flatt, Nigel Irwin, Dawood Khan, Srividya Vasu, R. Charlotte Moffett

المصدر: Molecular and cellular endocrinology. 436

مصطلحات موضوعية: 0301 basic medicine, Male, Hydrocortisone, Intracellular Space, Apoptosis, Biochemistry, Membrane Potentials, Endocrinology, Insulin-Secreting Cells, Insulin Secretion, Insulin, Cells, Cultured, geography.geographical_feature_category, digestive, oral, and skin physiology, Neuropeptide Y receptor, Islet, Beta cell, Somatostatin, PP cell, hormones, hormone substitutes, and hormone antagonists, medicine.drug, medicine.medical_specialty, Cell Survival, Biology, Pancreatic Polypeptide, Protective Agents, Glucagon, Streptozocin, Cell Line, 03 medical and health sciences, Insulin resistance, Internal medicine, medicine, Animals, Humans, Peptide YY, RNA, Messenger, Molecular Biology, Cell Proliferation, geography, Feeding Behavior, Glucose Tolerance Test, Streptozotocin, medicine.disease, Receptors, Neuropeptide Y, Mice, Inbred C57BL, 030104 developmental biology, Calcium, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e38e0e7f36e4b8bd2b3ccb0636708bTest
https://pubmed.ncbi.nlm.nih.gov/27465830Test

المؤلفون: Nigel Irwin, Hong Guo-Parke, Siobhan M. Scullion, Peter R. Flatt, Steven Patterson, R. Charlotte Moffett, Neville H. McClenaghan

المصدر: European journal of pharmacology. 771

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Homocysteine, medicine.medical_treatment, Gene Expression, Biology, Receptors, N-Methyl-D-Aspartate, Cell Line, Membrane Potentials, 03 medical and health sciences, chemistry.chemical_compound, Internal medicine, Insulin-Secreting Cells, Insulin Secretion, medicine, Animals, Hypoglycemic Agents, Insulin, Viability assay, Receptor, Pharmacology, Depolarization, Rats, 030104 developmental biology, Endocrinology, chemistry, Cell culture, NMDA receptor, Calcium, Signal transduction, Dizocilpine Maleate, Excitatory Amino Acid Antagonists, DNA Damage, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbca077f4224eff3976ce5e307bcb3aaTest
https://pubmed.ncbi.nlm.nih.gov/26688567Test

المؤلفون: Wim H. A. Dokter, Jeffry A. J. Wisse, E Bos, R. Charlotte Moffett, Nigel Irwin, Martin de Kort, Steven Patterson, André M. M. Miltenburg, Peter R. Flatt

المصدر: ChemMedChem. 10(8)

مصطلحات موضوعية: Agonist, Blood Glucose, endocrine system, medicine.medical_specialty, medicine.drug_class, Antithrombin III, Drug Evaluation, Preclinical, Mice, Obese, Oligosaccharides, Peptide, Biochemistry, Mice, Glucagon-Like Peptide 1, Internal medicine, Drug Discovery, medicine, Receptors, Glucagon, Glucose homeostasis, Animals, Humans, Hypoglycemic Agents, Insulin, General Pharmacology, Toxicology and Pharmaceutics, Receptor, Pharmacology, chemistry.chemical_classification, Glycated Hemoglobin, geography, geography.geographical_feature_category, Chemistry, Liraglutide, Venoms, Organic Chemistry, Biological activity, Glucose Tolerance Test, Islet, Mice, Inbred C57BL, Endocrinology, Diabetes Mellitus, Type 2, ROC Curve, Area Under Curve, Molecular Medicine, Exenatide, Peptides, medicine.drug, Half-Life, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de810e205685d76c366c58c4c1b22d7aTest
https://pubmed.ncbi.nlm.nih.gov/26059252Test

المؤلفون: Peter R. Flatt, R. Charlotte Moffett, Neville H. McClenaghan, Srividya Vasu

المصدر: Journal of molecular endocrinology. 54(1)

مصطلحات موضوعية: endocrine system, medicine.medical_specialty, Cell type, Cell Survival, medicine.medical_treatment, Gene Expression, Apoptosis, Biology, Streptozocin, Cell Line, Diabetes Mellitus, Experimental, Lethal Dose 50, Endocrinology, Downregulation and upregulation, Glucagon-Like Peptide 1, Internal medicine, Insulin-Secreting Cells, medicine, Animals, Viability assay, Cytotoxicity, Molecular Biology, Nitrites, Streptozotocin, Endoplasmic Reticulum Stress, Molecular biology, Mice, Inbred C57BL, Cytokine, Cell culture, Glucagon-Secreting Cells, Cytokines, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6790fc6db35937535a5c896d3b25ee1eTest
https://pubmed.ncbi.nlm.nih.gov/25527608Test

المؤلفون: Rachel, Lennox, Rachael R, Lennox, R Charlotte, Moffett, Charlotte, Moffett, David W, Porter, Nigel, Irwin, Victor A, Gault, Peter R, Flatt

المصدر: Molecular medicine reports. 12(4)

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Cell, Gene Expression, Biology, Hippocampal formation, Diet, High-Fat, Hippocampus, Biochemistry, Receptors, Gastrointestinal Hormone, Mice, Cognition, Memory, Internal medicine, Gene expression, Genetics, medicine, Animals, Insulin, Learning, Obesity, Receptor, Gene, Molecular Biology, PI3K/AKT/mTOR pathway, Mice, Knockout, Neuronal Plasticity, Oncogene, Molecular medicine, medicine.anatomical_structure, Endocrinology, Oncology, Apoptosis, Synaptic plasticity, Synaptophysin, biology.protein, Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4484b9a984dc0d1e3c471169df0b2e3Test
https://pubmed.ncbi.nlm.nih.gov/25760229Test

المؤلفون: Nigel Irwin, R. Charlotte Moffett, Jacqueline M. E. Francis, Peter R. Flatt

المصدر: PLoS ONE, Vol 8, Iss 11, p e78560 (2013)
PLoS ONE

مصطلحات موضوعية: Blood Glucose, medicine.medical_specialty, endocrine system, medicine.medical_treatment, Mammary gland, Abdominal Fat, Adipose tissue, Administration, Oral, lcsh:Medicine, Gastric Inhibitory Polypeptide, Biology, Weight Gain, Glucagon, Gastric inhibitory polypeptide, Mammary Glands, Animal, Pregnancy, Internal medicine, Lactation, medicine, Animals, Insulin, Rats, Wistar, lcsh:Science, Pancreas, geography, Multidisciplinary, geography.geographical_feature_category, lcsh:R, Organ Size, Islet, medicine.disease, Lipid Metabolism, Dietary Fats, Rats, Intestines, medicine.anatomical_structure, Endocrinology, Gene Expression Regulation, Female, lcsh:Q, Energy Intake, Transcriptome, hormones, hormone substitutes, and hormone antagonists, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8325932312948a49b2f22cca8cb7b2eTest
http://europepmc.org/articles/PMC3827257?pdf=renderTest