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1كتاب
المؤلفون: Carr, M, Lupu, E, Norton, J, Smith, L, Blackstock, J, Boyes, H, Hudson-Smith, A, Brass, I, Chizari, H, Cooper, R, Coulton, P, Craggs, Barney, Davies, N, De Roure, D, Elsden, M, Huth, M, Lindley, J, Marple, C, B, Mittelstadt, R, Nicolescu, J, Nurse, R, Proctor, Radanliev, P, Rashid, Awais, D, Sgandurra, Skatova, Anya, Taddeo, M, Tanczer, L, Vieira-Steiner, R, Watson, JDM, Wachter, S, Wakenshaw, S, Carvalho, G, Thompson, RJ, Westbury, PS
المساهمون: Taylor, P, Allpress, S
المصدر: Taylor , P (ed.) , Allpress , S (ed.) , Carr , M , Lupu , E , Norton , J , Smith , L , Blackstock , J , Boyes , H , Hudson-Smith , A , Brass , I , Chizari , H , Cooper , R , Coulton , P , Craggs , B , Davies , N , De Roure , D , Elsden , M , Huth , M , Lindley , J , Marple , C , B , M , R , N , J , N , R , P , ....
مصطلحات موضوعية: /dk/atira/pure/core/keywords/cyber_security, Cyber Security, IoT, Internet of Things, Human Factors, Ergonomics, Cyber Physical Systems, CPS
الوصف: This report examines the policy challenges for the Internet of Things (IoT), and raises a broad range of issues that need to be considered if policy is to be effective and the potential economic value of IoT is harnessed. It builds on the Blackett review, The Internet of Things: making the most of the second digital revolution, adding detailed knowledge based on research from the PETRAS Cybersecurity of the Internet of Things Research Hub and input from Fellows of the Royal Academy of Engineering. The report targets government policymakers, regulators, standards bodies and national funding bodies, and will also be of interest to suppliers and adopters of IoT products and services.
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المؤلفون: L, Pécheux, P, Forget, C, Geurten, L, Rausin, R, Nicolescu, C, Hoyoux
المصدر: Revue medicale de Liege. 73(11)
مصطلحات موضوعية: Male, Bone Diseases, Metabolic, Fractures, Spontaneous, Osteonecrosis, Humans, Pain, Female, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Child, Retrospective Studies
الوصف: Bone pain associated with bone marrow infiltration is often present at diagnosis of pediatric acute lymphoblastic leukemia (ALL). It sometimes signs the presence of pathological fracture, lytic lesions, arthritis, or osteitis associated to ALL that can delay the diagnosis. During treatment, bone complications (pain, osteopenia, fracture, avascular necrosis, ...) are also reported. In order to describe bone involvement (BI) of pediatric LLA, we reviewed the records of 104 patients followed in our unit. The overall incidence of BI was 67 %. At diagnosis, 50 % of patients had BI and in 19 %, the diagnosis of ALL was delayed. During and after treatment, respectively 28 % and 37 % of patients presented bone complications (pain, fractures, avascular necrosis, osteopenia). Patients with BI had a lower leukocytosis inferior to 10x109/l (p = 0.005) and an ALL of average risk (p = 0.019). 38 % of patients with BI during treatment were over 10 years old and 55 % were girls (vs. 21 % and 38 % in the entire cohort, respectively). Osteoporosis was more severe at diagnosis than during treatment, suggesting the presence of constitutional promoting factors. In our cohort, the majority of BI was resolved at the end of treatment with no long-term sequelae.Des douleurs osseuses sont souvent présentes au diagnostic des leucémies lymphoblastiques aiguës (LLA) pédiatriques. Elles signent aussi parfois la présence de fracture pathologique, de lésions lytiques, d’arthrite, ou d’ostéite associées qui peuvent retarder le diagnostic. Lors des traitements, des complications osseuses (douleurs, ostéopénie, fracture, nécrose avasculaire, …) sont également rapportées. Afin de décrire les atteintes osseuses (AO) des LLA pédiatriques, nous avons revu les dossiers de 104 patients suivis dans notre unité. L’incidence globale des AO était de 67 %. Au diagnostic, 50 % des patients avaient une AO et, chez 19 % d’entre eux, le diagnostic de LLA a été retardé. Pendant et après les traitements, respectivement 28 et 37 % des patients ont présenté des complications osseuses (douleurs, fractures, nécrose avasculaire, ostéopénie). Les patients avec AO avaient une leucocytose plus basse inf�rieur a 10x109/l (p = 0,005) et une LLA de risque moyen (p = 0,019). Chez les patients avec AO pendant les traitements, 38 % avaient plus de 10 ans et 55 % étaient des filles (vs 21 % et 38 % dans la cohorte entière). L’ostéoporose était plus sévère au diagnostic que pendant les traitements, suggérant la présence de facteurs favorisants constitutionnels. Dans notre cohorte, la majorité des AO étaient résolues après les traitements de LLA sans séquelles à long terme.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::efe93705e28d34e48f65bc93d5f4787dTest
https://pubmed.ncbi.nlm.nih.gov/30431247Test -
3دورية أكاديمية
المؤلفون: Y. Yasu, H. Fujii, Y. Igarishi, E. Inoue, H. Kodama, A. Manabe, Y. Watase, Y. Nagasaka, M. Nomachi, S. Hirano, H. Takagi, K. Shudo, T. Arai, L. Sarmenta, C. Thomborson, R. Nicolescu, M. Duc
المساهمون: The Pennsylvania State University CiteSeerX Archives
الوصف: We have evaluated a high speed network, Gigabit Ethernet(GbE), with Java/HORB, which means Java and Java-based Distributed Object Technology(DOT). Next generation of data acquisition(DAQ) needs high speed network such as ATM and GbE for data transfer in Level 3 and/or Level 2 trigger of the DAQ at large scale DAQ system like Large Hadron Collider(LHC). When evaluating the basic parameters of GbE, we considered bottleneck of network performance such as TCP buffer size, memory access speed, Maximum Transmission Unit(MTU) and so on. We used network tools called TTCP and Netperf and some Java benchmark programs for evaluating DOTs, namely, HORB, RMI and Voyager. Linux and Windows/NT operating systems Client Computer SW Network Interface Card Gigabit Ethernet Server Computer FIGURE 1. Setup for performance evaluation on PC computers, and Solaris on UltraSPARC workstation were used. MTU had an important role of the data transfer. When 2 Ultra30/Solaris systems via GbE were. Note: as at 14 April 2010, the archival site for this conference proceedings (http://www.hep.net/chep98Test) redirects to http://www.hep.net/chep95Test, which contains the proceedings of CHEP'95. http://www.particle.cz/conferences/chep2009/previouscheps.aspxTest lists the publishers for this series of conferences.
وصف الملف: application/postscript
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4مؤتمر
المؤلفون: M., Ţicleanu1, R., Nicolescu2, O., Colţoi3, F., Culescu2
المصدر: Proceedings of the International Multidisciplinary Scientific GeoConference SGEM. 2019, Vol. 19 Issue 1, p647-654. 8p.
مصطلحات موضوعية: *DIAPIRS, *SOLAR oscillations, *NEOGENE Period, *SOLAR system, *GEOLOGISTS, *FOLDS (Geology)
مستخلص: Our new perspective on possible cosmic causes of the tectonic phases as well as our attempt to elaborate a cyclostratigraphic chart of the Neogene for Central Paratethys, imposed a reconsideration of the key data on the Wallachian tectonic phase. Especially since this important moment was “abolished” by some modern authors. The Wallachian phase was defined by Hans Stille in connection with the Neogene–Quaternary limit. But this German geologist relied on the data of Romanian geologists who published, from 1907 to 1924, comments of an orogenic post-Pliocene movement. Subsequently, the Wallachian phase was denied by Macovei, was confused by several authors with the Pasadenian phase or was converted into a sub-stage of the final stage of the Alpine orogenesis. Initially, the appearing of the famous diapir folds of the extra-Carpathian area was exclusively attributed to post-Pliocene movements, but their formation is due to a greater number of Neogene tectonic phases, older than Wallachian phase. However the real effects of this phase were special and that is why this marks an important geological limit. So, the Wallachian phase also marks the beginning of the restriction of the Dacian Basin, the beginning of the accumulation of the “Cândesti Formation”, but also the beginning of the volcanic activity in Persani Mts. However this phase is especially the main cause of the folding and faulting of Pliocene deposits in the Carpathian area, of the accentuation of the diapir folds, but also of the formation of some ellipsoidal and circular tectonic structures, identified by us in the same area. In our opinion, the Wallachian phase connected with the Raup-Sepkoski cycles (R-S cycles, reflecting pulsations of our galaxy), is the last term of a geodynamic series with rare terms (at about 13 ma) and is preceded, in the Neogene, only by one phase of this series (the New-Styrian phase). All other Neogene phases could be moments of another series, with a frequency of 2.05 ma, due to a different cyclicity: Valach climatic cycle, highlighted by us, that must reflect possible pulsations of the Solar System. [ABSTRACT FROM AUTHOR]
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5مؤتمر
المؤلفون: J Grundy, Z Wei, R Nicolescu, Y Cai
مصطلحات موضوعية: web server, computer architecture, application software, software architechture, databases, Java, software testing, service oriented architecture, automatic testing, performance analysis
الوصف: Assessing the likely run-time performance of applications using thin-client architectures during their design is very difficult. We describe SoftArch/Thin, a thin-client test-bed generator that synthesises performance test-bed thin-client and server code from high-level software architecture models. This generated code is performance tested using a third-party tool and the results summarised. Architecture models can be evolved and tests repeated during application development to inform software engineers of realistic performance characteristics of their designs. Our environment currently supports J2EE and ASP.NET-based thin-client code generation and performance testing.
العلاقة: http://hdl.handle.net/10536/DRO/DU:30094706Test; https://figshare.com/articles/conference_contribution/An_environment_for_automated_performance_evaluation_of_J2EE_and_ASP_NET_thin-client_architectures/20889040Test
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المؤلفون: Olivier Claris, C. Levy-Marchal, O. Sibony, F. Kaguelidou, R. Nicolescu, J. Beltrand, D. Chevenne, R. Verkauskiene
المصدر: Aspects biologiques, moléculaires et cliniques de l’axe GH/IGF-I ISBN: 9782817801957
الوصف: Contexte : il a ete suggere que le retard de croissance fœtale (RCF) suivi d’une prise de poids rapide en debut de vie pourrait constituer la sequence initiale a l’origine de l’adiposite centrale et de l’insulinoresistance. Cependant, les liens entre croissance fœtale et croissance postnatale initiale avec les modifications metaboliques et anthropometriques qui y ont ete associees n’ont guere ete explores.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::d99913b9a16e84b5491d2b0ff5aaa383Test
https://doi.org/10.1007/978-2-8178-0196-4_13Test -
7
المؤلفون: Y. Cai, John Grundy, R. Nicolescu, Z. Wei
المصدر: Australian Software Engineering Conference
مصطلحات موضوعية: Web server, genetic structures, computer.internet_protocol, business.industry, Computer science, ASP.NET, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, Service-oriented architecture, Application software, computer.software_genre, ComputingMethodologies_PATTERNRECOGNITION, Software, Computer architecture, Thin client, Code generation, Software architecture, business, computer, computer.programming_language
الوصف: Assessing the likely run-time performance of applications using thin-client architectures during their design is very difficult. We describe SoftArch/Thin, a thin-client test-bed generator that synthesises performance test-bed thin-client and server code from high-level software architecture models. This generated code is performance tested using a third-party tool and the results summarised. Architecture models can be evolved and tests repeated during application development to inform software engineers of realistic performance characteristics of their designs. Our environment currently supports J2EE and ASP.NET-based thin-client code generation and performance testing.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::5b756d70d2a5d788ff0aa92cf7515f5eTest
https://doi.org/10.1109/aswec.2004.1290483Test -
8
المؤلفون: Claire Levy-Marchal, Jacques Beltrand, Pascal Gaucherand, Olivier Claris, R. Nicolescu, S. Deghmoun, O. Sibony, R. Verkauskiene
المصدر: Diabetes & Metabolism. 34:H29-H30
مصطلحات موضوعية: Endocrinology, Endocrinology, Diabetes and Metabolism, Internal Medicine, General Medicine
الوصف: Introduction On sait qu'un petit poids de naissance (PN) augmente le risque de developper une insulinoresistance (IR) et un diabete de type 2. Ce risque estil detectable des la naissance ? L'insulinemie du nouveau-ne reflete-t-elle deja l'IR ou seulement la croissance fœtale ? Le but est d'etudier la contribution du PN, de la vitesse de croissance fœtale (VCF) et de la composition corporelle sur la secretion d'insuline de nouveau-nes inclus dans une cohorte prospective des la periode fœtale. Patients et methodes Deux cent vingt-sept nouveau-nes a terme (38,9±1,9 SA ; 108 G/119 F) ont eu une mesure prospective de leur VCF entre 22 et 36 SA par echographie. (VCF : changement de percentiles du poids fœtal estime entre 22 SA et la naissance). L'insulinemie a la naissance a ete mesuree sur un prelevement de sang de cordon et la masse grasse estimee par la somme des 4 plis cutanes a J3 de vie. Resultats 61 nouveaux nes presentaient un PN vs 3,42±2,17 mUI/l ; p=0,01). Analyse multivariee : l'insulinemie a la naissance est correlee positivement au PN (p=0,01), et a la VCF (p=0,01), mais non au sexe ou a l'âge gestationnel. Lorsque la somme des plis est ajoutee au modele, l'insulinemie n'est plus correlee au poids de naissance, mais a la VCF (p=0,02) et a la somme des plis (p=0,03). Discussion Le ralentissement de croissance fœtale modifie la composition corporelle du nouveau-ne et s'associe a une insulinemie plus basse. Cette insulinemie reflete donc la qualite de la croissance fœtale et non un etat d'insulino-resistance. Conclusion Les effets de la programmation fœtale se reveleraient donc plus tard sous l'influence de la croissance et de la nutrition postnatale.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::08638e3c73e43424bbe7c88ba3b5dff6Test
https://doi.org/10.1016/s1262-3636Test(08)72874-x -
9دورية أكاديمية
المؤلفون: Y. Yasuy, H. Fujii, Y. Igarashi, E. Inoue, H. Kodama, A. Manabe, Y. Watase, Y. Nagasaka, M. Nomachi, S. Hirano, H. Takagi, K. Shudo, T. Arai, L. Sarmenta, C. Thomborson, R. Nicolescu, M. Ducyyyyyyyyy
المساهمون: The Pennsylvania State University CiteSeerX Archives
الوصف: Wehaveevaluated a high speed network, Gigabit Ethernet(GbE), with Java/HORB, which means Java and Java-based Distributed Object Technology(DOT). Next generation of data acquisition(DAQ) needs high speed network suchasATM and GbE for data transfer in Level 3 and/or Level 2 trigger of the DAQ at large scale DAQ system like Large Hadron Collider(LHC). When evaluating the basic parameters of GbE, we considered bottleneck of network performance such as TCP buffer size, memory access speed, Maximum Transmission Unit(MTU) and so on. We used network tools called TTCP and Netperf and some Java benchmark programs for evaluating DOTs, namely, HORB, RMI and Voyager. Linux and Windows/NT operating systems Client Computer SW Network Interface Card Gigabit Ethernet Server Computer FIGURE 1. Setup for performance evaluation on PC computers, and Solaris on UltraSPARCworkstation were used. MTU had an important role of the data transfer. When 2 Ultra30/Solaris systems via GbE were u.
وصف الملف: application/pdf
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10
المؤلفون: Konrad Bork, R. Nicolescu
المصدر: Archives for Dermatological Research. 249:301-311
مصطلحات موضوعية: Gynecology, medicine.medical_specialty, business.industry, Medicine, Dermatology, General Medicine, business
الوصف: Bei 5 Pseudoxanthoma elasticum-Kranken wurden angiologische Untersuchungen (elektronische Oscillographie, Venenverschlusplethysmographie, Bestimmung der Pulswellengeschwindigkeit im Rumpf, Belastungs-EKG) durchgefuhrt. Bei allen Patienten wird unabhangig von der weiteren Symptomatik eine Minderung der peripheren Durchblutung festgestellt. Bei fehlender Coronarinsuffizienz und fehlender manifester Hypertonie wird eine signifikant verminderte korperliche Belastbarkeit fahrradergometrisch nachgewiesen, die auf periphere Durchblutungsminderung zuruckzufuhren ist. Im Gegensatz zu Arteriosklerose und Hypertonie ist die Pulswellengeschwindigkeit im Rumpf bei Pseudoxanthoma elasticum normal. Damit ist die Pulswellengeschwindigkeit ein wichtiges klinisches, differentialdiagnostisches Kriterium zur Abgrenzung der Gefasveranderungen bei Pseudoxanthoma elasticum von denen bei den oben genannten Krankheitsbildern.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::e7105e0e11148a7d1615386bf1c67116Test
https://doi.org/10.1007/bf00557890Test