المؤلفون: Lingaraju, Gondichatnahalli M., Prota, Andrea E., Winkler, Fritz K.

المصدر: DNA Repair ; volume 8, issue 7, page 857-864 ; ISSN 1568-7864

مصطلحات موضوعية: Cell Biology, Molecular Biology, Biochemistry

الإتاحة: https://doi.org/10.1016/j.dnarep.2009.03.009Test
https://api.elsevier.com/content/article/PII:S1568786409000937?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1568786409000937?httpAccept=text/plainTest

المؤلفون: Marzullo, Paola, Boiarska, Zlata, Pérez‐Peña, Helena, Abel, Anne‐Catherine, Álvarez‐Bernad, Beatriz, Lucena‐Agell, Daniel, Vasile, Francesca, Sironi, Maurizio, Altmann, Karl‐Heinz, Prota, Andrea E., Díaz, J. Fernando, Pieraccini, Stefano, Passarella, Daniele

المصدر: Chemistry - A European Journal; 1/10/2022, Vol. 28 Issue 2, p1-1, 1p

مصطلحات موضوعية: TUBULINS, X-ray crystallography, MOLECULAR docking

المؤلفون: Wagner, Armin, Pieren, Michel, Schulze-Briese, Clemens, Ballmer-Hofer, Kurt, Prota, Andrea E.

المصدر: Acta Crystallographica: Section D (Wiley-Blackwell); Nov2006, Vol. 62 Issue 11, p1430-1434, 5p, 1 Diagram, 1 Chart, 1 Graph

مصطلحات موضوعية: VASCULAR endothelial growth factors, CRYSTALLOGRAPHY, SULFUR, METHIONINE, SYNCHROTRONS, DISPERSION (Chemistry)

المؤلفون: Chappell, James D.^1,2, Prota, Andrea E.³, Dermody, Terence S.^1,2,4 tstehle@partners.org, Stehle, Thilo³ terry.dermody@mcmail.vanderbilt.edu

المصدر: EMBO Journal. 1/1/2002, Vol. 21 Issue 1/2, p1-11. 11p.

مصطلحات موضوعية: *REOVIRUSES, *CELL receptors, *PROTEINS, *ADENOVIRUSES, *BINDING sites, *VIRUSES

المؤلفون: Abel, Anne-Catherine^1,2, Mühlethaler, Tobias², Dessin, Cedric³, Schachtsiek, Thomas³, Sammet, Benedikt³, Sharpe, Timothy², Steinmetz, Michel O.^1,2, Sewald, Norbert³ norbert.sewald@uni-bielefeld.de, Prota, Andrea E.¹ andrea.prota@psi.ch

المصدر: Journal of Biological Chemistry. Jun2024, Vol. 300 Issue 6, p1-10. 10p.

مصطلحات موضوعية: *STRUCTURE-activity relationships, *BINDING sites, *ATOMIC interactions, *HETERODIMERS, *TUBULINS

المؤلفون: Jost, Marco, Chen, Yuwen, Gilbert, Luke A, Horlbeck, Max A, Krenning, Lenno, Menchon, Grégory, Rai, Ankit, Cho, Min Y, Stern, Jacob J, Prota, Andrea E, Kampmann, Martin, Akhmanova, Anna, Steinmetz, Michel O., Tanenbaum, Marvin E, Weissman, Jonathan S, Sub Cell Biology, Celbiologie

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research, Sub Cell Biology, Celbiologie

المصدر: Molecular Cell, 68(1), 210. Cell Press
Molecular Cell
Molecular Cell, 68(1), 210-223.e6. Cell Press
Molecular cell, vol 68, iss 1

مصطلحات موضوعية: 0301 basic medicine, Drug Resistance, Kinesins, Medical and Health Sciences, Microtubules, Tubulin, 2.1 Biological and endogenous factors, RNA, Guide, Sulfones, Kinetoplastida, Aetiology, Cancer, Genetics, Gene knockdown, rigosertib, Rigosertib, Kinesin, Biological Sciences, drug mechanism of action, Tubulin Modulators, 3. Good health, Gene Expression Regulation, Neoplastic, chemical genetics, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Chemical genetics, RNA, Guide, Kinetoplastida, Biotechnology, Recombinant Fusion Proteins, Genetic Vectors, Glycine, Antineoplastic Agents, Computational biology, Biology, Vinblastine, Article, Small Molecule Libraries, microtubules, 03 medical and health sciences, CRISPRa, Rare Diseases, Microtubule, Journal Article, Humans, Genetic Testing, Molecular Biology, drug target identification, Neoplastic, Human Genome, Lentivirus, CRISPRi, Cell Biology, genome-wide CRISPR screening, Orphan Drug, 030104 developmental biology, Gene Expression Regulation, Drug Resistance, Neoplasm, Myelodysplastic Syndromes, Mutation, biology.protein, Neoplasm, RNA, CRISPR-Cas Systems, Colchicine, K562 Cells, Guide, Developmental Biology, HeLa Cells, Genetic screen

وصف الملف: image/pdf; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f179af91573489aafc58613822af4048Test

المؤلفون: Weinert, Tobias, Olieric, Vincent, Waltersperger, Sandro, Panepucci, Ezequiel, Chen, Lirong, Zhang, Hua, Zhou, Dayong, Rose, John, Ebihara, Akio, Kuramitsu, Seiki, Li, Dianfan, Howe, Nicole, Schnapp, Gisela, Pautsch, Alexander, Bargsten, Katja, Prota, Andrea E, Surana, Parag, Kottur, Jithesh, Nair, Deepak T, Basilico, Federica

المصدر: Nature Methods; Jul2015, Vol. 12 Issue 7, p692-692, 1p

مصطلحات موضوعية: MACROMOLECULES, MOLECULES

المؤلفون: Paola Marzullo, Maurizio Sironi, Daniel Lucena-Agell, J. Fernando Díaz, Daniele Passarella, Helena Pérez-Peña, Zlata Boiarska, Stefano Pieraccini, Beatriz Álvarez-Bernad, Anne-Catherine Abel, Karl-Heinz Altmann, Andrea E. Prota, Francesca Vasile

المساهمون: European Commission, Ministerio de Ciencia e Innovación (España), Consejo Superior de Investigaciones Científicas (España), Fundación Tatiana Pérez de Guzmán el Bueno, Università degli Studi di Milano, Marzullo, Paola, Boiarska, Zlata, Abel, Anne-Catherine, Álvarez-Bernad, Beatriz, Lucena-Agell, Daniel, Vasile, Francesca, Sironi, Maurizio, Altmann, Karl-Heinz, Prota, Andrea E., Díaz, José Fernando, Pieraccini, Stefano, Passarella, D., Marzullo, Paola [0000-0003-4249-8794], Boiarska, Zlata [0000-0003-1235-5717], Abel, Anne-Catherine [0000-0002-2392-9029], Álvarez-Bernad, Beatriz [0000-0002-2492-9215], Lucena-Agell, Daniel [0000-0001-7198-2900], Vasile, Francesca [0000-0002-3926-8261], Sironi, Maurizio [0000-0001-5822-4849], Altmann, Karl-Heinz [0000-0002-0747-9734], Prota, Andrea E. [0000-0003-0875-5339], Díaz, José Fernando [0000-0003-2743-3319], Pieraccini, Stefano [0000-0002-7672-0720], Passarella, D. [0000-0001-6180-9581]

المصدر: Chemistry – A European Journal
Digital.CSIC. Repositorio Institucional del CSIC
instname
Chemistry-A European Journal, 28 (2)

مصطلحات موضوعية: maytansine binding site, Cancer therapy, 01 natural sciences, Catalysis, microtubules, Acylation, 03 medical and health sciences, Maytansinol, Microtubule, Neoplasms, Humans, Molecule, Maytansine, 030304 developmental biology, 0303 health sciences, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, General Chemistry, maytansinol, tubulin, tubulin binders, Combinatorial chemistry, Tubulin Modulators, 0104 chemical sciences, 3. Good health, Tubulin, Docking (molecular), biology.protein

وصف الملف: application/application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3462138c4725ef6c10a3c34703000338Test
http://hdl.handle.net/10261/257058Test

المؤلفون: María A. Oliva, Susan Matthew, Ranjala Ratnayake, Hendrik Luesch, Francesca Bonato, April L. Risinger, Andrea E. Prota, Daniel Lucena-Agell, Seok Ting Lim, Qi-Yin Chen, J. Fernando Díaz, Charles S. Fermaintt, Xiaomeng Wang, Valerie J. Paul

المساهمون: National Cancer Institute (US), National Institute of General Medical Sciences (US), University of Florida, Ministerio de Ciencia e Innovación (España), Consejo Superior de Investigaciones Científicas (España), European Commission, Matthew, S. [0000-0003-4943-4777], Chen, Qi-Yin [0000-0002-4364-1057], Ratnayake, R. [0000-0002-5980-2070], Fermaintt, Charles S. [0000-0001-8140-5461], Lucena-Agell, Daniel [0000-0001-7198-2900], Bonato, Francesca [0000-0002-0579-2874], Prota, Andrea E. [0000-0003-0875-5339], Lim, Seok Ting [0000-0002-5173-5715], Wang, Xiaomeng [0000-0002-1036-2764], Díaz, José Fernando [0000-0003-2743-3319], Risinger, April L. [0000-0002-4363-3268], Paul, Valerie J. [0000-0002-4691-1569], Oliva, María A. [0000-0002-2215-4639], Luesch, H. [0000-0002-4091-7492], Matthew, S., Chen, Qi-Yin, Ratnayake, R., Fermaintt, Charles S., Lucena-Agell, Daniel, Bonato, Francesca, Prota, Andrea E., Lim, Seok Ting, Wang, Xiaomeng, Díaz, José Fernando, Risinger, April L., Paul, Valerie J., Oliva, María A., Luesch, H.

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Proc Natl Acad Sci U S A

مصطلحات موضوعية: Models, Molecular, Protein Conformation, alpha-Helical, Marine natural product, Antineoplastic Agents, Apoptosis, Total synthesis, Crystallography, X-Ray, Cyanobacteria, 01 natural sciences, Pentapeptide repeat, Microtubules, 03 medical and health sciences, chemistry.chemical_compound, Bacterial Proteins, Microtubule, Tubulin, Cell Line, Tumor, Depsipeptides, Drug Discovery, Humans, Maytansine, Protein Interaction Domains and Motifs, Binding site, Vinca Alkaloids, 030304 developmental biology, 0303 health sciences, Biological Products, Multidisciplinary, Natural product, Binding Sites, biology, Chemotype, 010405 organic chemistry, Biological Sciences, HCT116 Cells, In vitro, Tubulin Modulators, 3. Good health, 0104 chemical sciences, chemistry, Biochemistry, Pyrones, biology.protein, Protein Conformation, beta-Strand, Taxoids, Colchicine, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c3e59a13700d6bc432e5889d60967dTest
http://hdl.handle.net/10261/235164Test

المؤلفون: Isabel Barasoain, Andrea E. Prota, J. Fernando Díaz, Francisco de Asís Balaguer, Christina Kamma-Lorger, Siou Ku, María A. Oliva, Rubén M. Buey, Toshiki Yagi, Laurence Duchesne, Denis Chrétien, Daniel Lucena-Agell, Shinji Kamimura, Juan Estévez-Gallego, Michel O. Steinmetz, Hiroyuki Iwamoto, Fernando Josa-Prado

المساهمون: Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Institut de Génétique et Développement de Rennes (IGDR), Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Department of Structural Engineering - University of Naples 'Federico II', Microbiologia Molecular, Centro Investigaciones Biologicas. CSIC, Institut Jacques Monod (IJM (UMR_7592)), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Biomolecular Research, Structural Biology, Paul Scherrer Institute (PSI), Interactions cellulaires et moléculaires (ICM), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS), BFU2013-47014P, Ministerio de Economía y Competitividad, H2020-MSCA-ITN-EJD-860070, H2020 European Research Council, 31003A_166608, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, KAKENHI 16K07328/17H03668, Japan Society for the Promotion of Science, ANR-16-C11-0017-01, Agence Nationale de la Recherche, 2019B1365, SPring-8 Proposal, Ministerio de Economía y Competitividad (España), Ministerio de Ciencia e Innovación (España), European Commission, Swiss National Science Foundation, Ministerio de Educación, Cultura y Deporte (España), Estévez-Gallego, Juan, Josa-Prado, Fernando, Martínez Buey, Rubén, Prota, Andrea E., Lucena-Agell, Daniel, Kamma-Lorger, C.S., Yagi, Toshiki, Barasoain, Isabel, Steinmetz, Michel O., Kamimura, Shinji, Díaz, José Fernando, Oliva, María A., Estévez-Gallego, Juan [0000-0003-3889-8488 ], Josa-Prado, Fernando [0000-0002-6162-3231], Martínez Buey, Rubén [0000-0003-1263-0221], Prota, Andrea E. [0000-0003-0875-5339], Lucena-Agell, Daniel [0000-0001-7314-8696], Kamma-Lorger, C.S. [0000-0001-6686-9161], Yagi, Toshiki[0000-0002-1379-460X], Barasoain, Isabel [0000-0003-2013-085X], Steinmetz, Michel O. [0000-0001-6157-3687], Kamimura, Shinji [0000-0003-4359-0859], Díaz, José Fernando [0000-0003-2743-3319], Oliva, María A. [0000-0002-2215-4639], Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), University of Naples Federico II = Università degli studi di Napoli Federico II, Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS), ANR-16-CE11-0017,Tubulin_GTP,Mécanisme d'hydrolyse du GTP lors de l'assemblage des microtubules(2016)

المصدر: eLife
eLife, eLife Sciences Publication, 2020, 9, pp.e50155. ⟨10.7554/eLife.50155⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
'eLife ', vol: 9, pages: e50155-1-e50155-26 (2020)
eLife, Vol 9 (2020)
eLife, 2020, 9, pp.e50155. ⟨10.7554/eLife.50155⟩

مصطلحات موضوعية: Models, Molecular, none, Structural Biology and Molecular Biophysics, [SDV]Life Sciences [q-bio], Molecular Conformation, GTPase, Microtubules, 0302 clinical medicine, Tubulin, structural biology, Nucleotide, Biology (General), ComputingMilieux_MISCELLANEOUS, chemistry.chemical_classification, 0303 health sciences, taxol, biology, Chemistry, General Neuroscience, dynamic instability, General Medicine, Molecular biophysics, Medicine, Guanosine Triphosphate, Structural biology, Research Article, microtubule, QH301-705.5, Taxol, Science, Microtubule, Dynamic instability, macromolecular substances, Guanosine Diphosphate, General Biochemistry, Genetics and Molecular Biology, Structure-Activity Relationship, 03 medical and health sciences, None, Pi, molecular biophysics, 030304 developmental biology, GTP-cap, General Immunology and Microbiology, Cell growth, Cryoelectron Microscopy, Hydrogen Bonding, biology.protein, Biophysics, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f00c01fd31baf004ef430cbc4a55d6Test
https://hal.archives-ouvertes.fr/hal-02552246/file/hal-02552246.pdfTest