المؤلفون: Anand, Achala, Arya, Aditya, Raghav, Aditya, Jastrzębska, Agnieszka Maria, Ahalya N., Dhara, Aiindrila, Khanday, Akib Mohi Ud Din, Kumar, Ambuj, Singh, Amisha, Panda, Amrita Kumari, Ali, Anamta, Vishnu G.K., Anil, Lathwal, Anjali, Choudhary, Ankit, Rangarajan, Annapoorni, Chandra, Anshuman, Sengar, Anugya, Raha, Arnab, Nallakumarasamy, Arulkumar, Adil, Asif, Choudhuri, Avik, Sengupta, Avik, Gupta, Ayushi, Pakala, B. Suresh, Dwarakanath, B.S., Banerjee, Basudha, Sharma, Bhawna, Thirumal Kumar, D., Kalpdev, Daizy, Hoessli, Daniel C., Baishya, Debabrat, Pradhan, Dibyabhaba, Flynn, Emmet, Caruso, Gerardo, Sehrawat, Himanshu, Inbanathan, Jaiganesh, Dhanjal, Jaspreet Kaur, Shandilya, Jayasha, Pernaa, Johannes, Talukdar, Joyeeta, Ponnazhagan, K., Mishra, Kaushala Prasad, Bharadwaj, Kaushik Kumar, Kundal, Kavita, Kumar, Keerthana Vinod, Raza, Khalid, Bhutani, Khushboo, Gandhi, Khushi, R., Kunjulakshmi, Zon, Leonard I.

المصدر: Computational Biology for Stem Cell Research ; page xxxiii-xxxvii ; ISBN 9780443132223

الإتاحة: https://doi.org/10.1016/b978-0-443-13222-3.01002-9Test
https://api.elsevier.com/content/article/PII:B9780443132223010029?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:B9780443132223010029?httpAccept=text/plainTest

المؤلفون: Inbanathan, Jaiganesh, Anitha, R., Biswas, Protyusha Guha, Sanjana, M.R., Ponnazhagan, K., Thirumal Kumar, D.

المصدر: Computational Biology for Stem Cell Research ; page 51-64 ; ISBN 9780443132223

الإتاحة: https://doi.org/10.1016/b978-0-443-13222-3.00022-8Test
https://api.elsevier.com/content/article/PII:B9780443132223000228?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:B9780443132223000228?httpAccept=text/plainTest

المؤلفون: Sivakumar, J, Anitha, G, Ponnazhagan, K

المصدر: Asian Journal of Medical Sciences; Vol. 13 No. 6 (2022); 57-61 ; 2091-0576 ; 2467-9100

مصطلحات موضوعية: COVID-19, C-reactive protein, Interleukin-6, Lactate dehydrogenase, Vitamin-D

الوصف: Background: SARS-COV-2 is also known as coronavirus causes an infectious disease has caused a global concern due to its pandemic nature. In India, nearly 36 million cases and 5.1 lakh deaths have been recorded so far. Laboratory biomarkers play an important role in improving the clinical situational awareness by predicting risk stratification and by discriminating between severe and non-severe cases. There is no sufficient information available regarding the role of C-reactive protein (CRP), lactate dehydrogenase (LDH), Vitamin D, and interleukin-6 (IL-6) in the prognosis of COVID-19 patients in Southern part of India. Aims and Objectives: We aim to retrospectively analyze CRP, LDH, Vitamin D, and IL-6 in COVID-19 patients. Materials and Methods: The observational and retrospective study was carried out from the case records of 103 patients from November 2021 to February 2022 in which CRP, LDH, Vitamin D, IL-6, COVID-19 Reporting and Data System (CO-RADS), and CT sore were analyzed during admission and follow-up period in the hospital. Mean, mean difference, standard deviation, standard error difference, and P value were calculated. P<0.05 was considered to be significant. Results: CRP, LDH, IL-6, Vitamin D, CO-RADS, and CT score were decreased during the follow-up period when these levels were compared at the time of admission in the hospital, while there is an increase in Vitamin D levels during the follow-up period. Conclusion: The use of reliable and easy to use assays such as CRP, LDH, Vitamin D, and IL-6 plays an important role in the diagnosis and prognosis of COVID-19.

وصف الملف: application/pdf

العلاقة: https://www.nepjol.info/index.php/AJMS/article/view/43913/34033Test; https://www.nepjol.info/index.php/AJMS/article/view/43913Test

الإتاحة: https://www.nepjol.info/index.php/AJMS/article/view/43913Test

المؤلفون: Narasimhamurthy, K.N., Daruka Prasad, B., Radha Krushna, B.R., Sharma, S.C., Ponnazhagan, K., Francis, Dileep, Nijalingappa, T.B., Nasreen Taj, M., Nagabhushana, H.

المصدر: Inorganic Chemistry Communications ; volume 156, page 111161 ; ISSN 1387-7003

الإتاحة: https://doi.org/10.1016/j.inoche.2023.111161Test
https://api.elsevier.com/content/article/PII:S1387700323007736?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1387700323007736?httpAccept=text/plainTest

المؤلفون: Sivakumar, J.¹ drshivakumar21@gmail.com, Ponnazhagan, K.², Gopalakrishnan, T.³

المصدر: Asian Journal of Medical Sciences. Nov2021, Vol. 12 Issue 11, p71-78. 8p.

مصطلحات موضوعية: *LABORATORY rats, *VITAMIN D, *RAT diseases, *LIVER diseases, *FREE fatty acids

مستخلص: Background: Liver is the largest gland, accounts for approximately 2.5% of total body weight and also liver called as the metabolic "engine-room of the body." Liver plays role in both metabolism as well as biochemical transformation. Therefore, it is vital to maintain a healthy liver for overall health and well-being. However, liver is continuously exposed to exogenous substances such as toxins, drugs, and alcohol which can ultimately lead to various liver disorders. Liver diseases today are one of the most fatal diseases globally. Aims and Objectives: The aim of the present study was to evaluate lipid peroxidation (LPO) and lipid profile levels of Vitamin D and combination with Liv-52 on carbon tetrachloride induced liver disease in rats. Materials and Methods: Thirty-six adult male Albino Wistar rats weighing 150-200 g were used in this study. Liver disease was induced in rats by administration of Carbon tetrachloride (CCl4) intraperitoneally at the dose of 1 mL mixed with 50% of olive oil twice a week for 5 weeks, 3 days interval between each dose, after confirmation of liver disease treated with Vitamin D and Liv-52 for 5 weeks. Results: The levels of LPO were significantly decreased in Vitamin D and Liv-52 treated animals when compared with CCl4 induced animals. Total cholesterol, free cholesterol, phospholipids, and triglycerides (TGs) levels were significantly reduced when compared with CCl4 induced rats. However, the levels of ester cholesterol and free fatty acids (FFAs) were significantly increased in Vitamin D and Liv-52 treated animals when compared with CCl4 induced animals. Conclusion: Vitamin D and Liv-52 effectively reduced the LPO levels. Treatment with Vitamin D and Liv-52, the levels of total and free cholesterol, phospholipids, and TGs were significantly reduced and treatment with both combinations highly reduced all these levels when compared with CCl4 induced animals. And treatment with Vitamin D and Liv-52, the ester cholesterol and FFAs levels were increased. [ABSTRACT FROM AUTHOR]