المؤلفون: Traore, Ibrahim, Eberst, Guillaume, Claudé, Fréderic, Laurent, Lucie, Meurisse, Aurelia, Paget-Bailly, Sophie, Roux-Claudé, Pauline, Jacoulet, Pascale, Barnig, Cindy, Martarello, Rachel, Poirson, Bastien, Bouiller, Kevin, Chirouze, Catherine, Behr, Julien, Grillet, Franck, Ritter, Ophélie, Pili-Floury, Sébastien, Winiszewski, Hadrien, Samain, Emmanuel, Capellier, Gilles, Westeel, Virginie

المصدر: Nature and Science of Sleep ; volume Volume 14, page 2213-2225 ; ISSN 1179-1608

الإتاحة: https://doi.org/10.2147/nss.s377946Test
https://www.dovepress.com/getfile.php?fileID=86335Test

المؤلفون: Guillaumin, Michel, Poirson, Bastien, Gerazime, Aurélie, Puyraveau, Marc, Tannou, Thomas, Mauny, Fréderic, Toussirot, Éric

المصدر: Frontiers in Aging ; volume 3 ; ISSN 2673-6217

الوصف: Background: Osteoporosis consists in the reduction of bone mineral density and increased risk of fracture. Age is a risk factor for osteoporosis. Although many treatments are available for osteoporosis, there is limited data regarding their efficacy in older people. Objective: To evaluate the efficacy of osteoporosis treatments in patients over 75 years old. Methods: We reviewed all published studies in MEDLINE, Cochrane and EMBASE including patients over 75 years old, treated by osteoporosis drugs, and focused on vertebral fractures or hip fractures. Results: We identified 4,393 records for review; 4,216 were excluded after title/abstract review. After full text review, 19 records were included in the systematic review. Most studies showed a reduction in vertebral fracture with osteoporosis treatments, but non-significant results were observed for hip fractures. Meta-analysis of 10 studies showed that lack of treatment was significantly associated with an increased risk of vertebral fractures at one (OR = 3.67; 95%CI = 2.50–5.38) and 3 years (OR = 2.19; 95%CI = 1.44–3.34), and for hip fractures at one (OR = 2.14; 95%CI = 1.09–4.22) and 3 years (OR = 1.31, 95%CI = 1.12–1.53). Conclusion: A reduction in the risk of vertebral fractures with osteoporosis treatments was observed in most of the studies included and meta-analysis showed that lack of treatment was significantly associated with an increased risk of vertebral fractures. Concerning hip fractures, majority of included studies did not show a significant reduction in the occurrence of hip fractures with osteoporotic treatments, but meta-analysis showed an increased risk of hip fractures without osteoporotic treatment. However, most of the data derived from post hoc and preplanned analyses or observational studies.

الإتاحة: https://doi.org/10.3389/fragi.2022.845886Test

المؤلفون: Poirson, Bastien, Galli, Silvio, Bourdin, Hubert

المصدر: Médecine du Sommeil ; volume 19, issue 1, page 63 ; ISSN 1769-4493

مصطلحات موضوعية: Behavioral Neuroscience, Neurology (clinical), Cognitive Neuroscience, Neurology, Neuropsychology and Physiological Psychology

الإتاحة: https://doi.org/10.1016/j.msom.2022.01.032Test
https://api.elsevier.com/content/article/PII:S1769449322000322?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1769449322000322?httpAccept=text/plainTest

المؤلفون: Poirson, Bastien, Galli, Silvio, Bourdin, Hubert

المصدر: Médecine du Sommeil ; volume 19, issue 1, page 36 ; ISSN 1769-4493

مصطلحات موضوعية: Behavioral Neuroscience, Neurology (clinical), Cognitive Neuroscience, Neurology, Neuropsychology and Physiological Psychology

الإتاحة: https://doi.org/10.1016/j.msom.2022.01.139Test
https://api.elsevier.com/content/article/PII:S176944932200139X?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S176944932200139X?httpAccept=text/plainTest