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1رسالة جامعية
المؤلفون: Pilavakis, Yiannis
مرشدي الرسالة: Ihler, Friedrich Prof. Dr.
مصطلحات موضوعية: 610, chronic, rhinosinusitis, allergy, Oto-Rhino-Laryngologie (PPN619876220)
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2دورية أكاديمية
المؤلفون: Mechie, Nicolae-Catalin, Burmester, Merle, Mavropoulou, Eirini, Pilavakis, Yiannis, Kunsch, Steffen, Ellenrieder, Volker, Amanzada, Ahmad
المساهمون: Mechie, Nicolae-Catalin, Burmester, Merle, Mavropoulou, Eirini, Pilavakis, Yiannis, Kunsch, Steffen, Ellenrieder, Volker, Amanzada, Ahmad
الإتاحة: https://doi.org/10.1097/MD.0000000000025111Test
https://resolver.sub.uni-goettingen.de/purl?gro-2/134812Test -
3دورية أكاديمية
المؤلفون: Leu, Martin, Patzer, Christoph, Guhlich, Manuel, Possiel, Jacqueline, Pilavakis, Yiannis, Schirmer, Markus Anton, Rieken, Stefan, Dröge, Leif Hendrik
الوصف: Locally advanced head and neck squamous cell carcinomas (HNSCC) are often managed with surgery followed by postoperative radiochemotherapy (RCT). With the general increase in life expectancy, the proportion of elderly patients with HNSCC is expected to grow rapidly. Until now, a deeper understanding of specific management strategies for these patients in clinical routine was lacking. In the present study, we compared elderly patients (≥70 years, n = 52) and younger patients (n = 245) treated with postoperative RCT for HNSCC at our tertiary cancer center. All patients were irradiated with modern radiotherapy techniques (IMRT/VMAT). Patients ≥70 years of age had more comorbidities. Additionally, elderly patients less frequently received concomitant systemic treatment. The rates of mucositis and dermatitis were lower in patients ≥70 years. Elderly patients had significantly worse overall and progression-free survival. Locoregional and distant control were comparable in elderly and younger patients. In conclusion, postoperative RCT is a safe and effective treatment option in patients ≥70 years. In light of comorbidities and poor overall survival rates, benefits and harms of radiotherapy and concomitant systemic treatment should be weighed carefully. When exclusively applying up-to-date radiotherapy techniques with, at the same time, careful use of concomitant systemic therapy, favorable acute toxicity profiles are achieved. ; Locally advanced head and neck squamous cell carcinomas (HNSCC) are often managed with surgery followed by postoperative radiochemotherapy (RCT). With the general increase in life expectancy, the proportion of elderly patients with HNSCC is expected to grow rapidly. Until now, a deeper understanding of specific management strategies for these patients in clinical routine was lacking. In the present study, we compared elderly patients (≥70 years, n = 52) and younger patients (n = 245) treated with postoperative RCT for HNSCC at our tertiary cancer center. All patients were irradiated with modern ...
العلاقة: https://resolver.sub.uni-goettingen.de/purl?gro-2/89222Test; cancers13143384
الإتاحة: https://doi.org/10.3390/cancers13143384Test
https://resolver.sub.uni-goettingen.de/purl?gro-2/89222Test -
4دورية أكاديمية
المساهمون: Spiegel, Jennifer L., Pilavakis, Yiannis, Canis, Martin, Welz, Christian
الوصف: Background: The pedicled supraclavicular artery island flap (SCAIF) for reconstruction of the head and neck has been shown to be a pliable alternative to established pedicled flaps, such as the pectoralis major myocutaneous flap. Because there are limited published data regarding shoulder morbidity after SCAIF procedure, we aimed to investigate it with 2 established questionnaires for the upper extremity [Constant-Murley score and Disabilities of the Arm, Shoulder and Hand Outcome Measure (DASH) score]. Methods: The authors designed and implemented a retrospective cohort study of patients who received a defect reconstruction by SCAIF. Analyzed parameters were demographics, comorbidities, donor-site morbidity and shoulder morbidity in terms of range of motion, pain, strength, and daily activities evaluated and compared between the donor site and contralateral arm. Results: Of the 61 consecutively performed head and neck reconstructions with SCAIF, 20 met inclusion criteria (curative intended treatment, head and neck squamous cell cancer, follow-up time more than 4 months). Mean follow-up was 17.3 months (±10.4 months) ranging from 4–35 months. Donor-site complication rate was low with 5% major (surgical revision) and 30% minor complications (conservative management). Overall Constant-Murley-Score ( P = 0.334), pain ( P = 0.150), overall range of motion ( P = 0.861), and strength of the extremity ( P = 0.638) of the shoulder receiving a SCAIF showed no significant differences to the contralateral extremity. Mean of Disabilities of the Arm, Shoulder and Hand Outcome Measure score was 32.5 (±28.6). Conclusion: The results of the present study suggest very low shoulder morbidity in patients after SCAIF procedure with no significant functional impairment of the donor shoulder compared with the contralateral side.
الإتاحة: https://doi.org/10.1097/GOX.0000000000001711Test
https://resolver.sub.uni-goettingen.de/purl?gro-2/134751Test -
5دورية أكاديمية
المؤلفون: Mavropoulou, Eirini, Mechie, Nicolae-Catalin, Knoop, Richard, Petzold, Golo, Ellenrieder, Volker, Kunsch, Steffen, Pilavakis, Yiannis, Amanzada, Ahmad
المساهمون: Bonaz, Bruno
الوصف: Open-Access-Publikationsfonds 2020
العلاقة: https://resolver.sub.uni-goettingen.de/purl?gro-2/81557Test; https://resolver.sub.uni-goettingen.de/purl?gs-1/17632Test
الإتاحة: https://doi.org/10.1371/journal.pone.0233811Test
https://resolver.sub.uni-goettingen.de/purl?gro-2/81557Test
https://resolver.sub.uni-goettingen.de/purl?gs-1/17632Test -
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8دورية أكاديمية
المؤلفون: Weiss, Bernhard G., Ihler, Friedrich, Pilavakis, Yiannis, Wolff, Hendrik A., Canis, Martin, Welz, Christian, Steiner, Wolfgang
المصدر: European Archives of Oto-Rhino-Laryngology ; volume 274, issue 4, page 1997-2004 ; ISSN 0937-4477 1434-4726
مصطلحات موضوعية: General Medicine, Otorhinolaryngology
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9دورية أكاديمية
المصدر: Surgical and Radiologic Anatomy ; volume 39, issue 4, page 461-465 ; ISSN 0930-1038 1279-8517
مصطلحات موضوعية: Radiology, Nuclear Medicine and imaging, Pathology and Forensic Medicine, Surgery, Anatomy
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10دورية أكاديمية
المؤلفون: Ibrahim, Michael, Fanshawe, Angela, Patel, Vanash, Goswami, Karan, Chilvers, Geoffrey, Ting, Michelle, Pilavakis, Yiannis, Rao, Christopher, Athanasiou, Thanos
المصدر: Medical Teacher ; volume 36, issue 12, page 1064-1072 ; ISSN 0142-159X 1466-187X
النص الكامل