المؤلفون: Loesche, Christian, Picard, Damien, Van Hoorick, Benjamin, Schuhmann, Imelda, Jäger, Petra, Klein, Kai, Schuhler, Carole, Thoma, Gebhard, Markert, Christian, Poller, Birk, Zamurovic, Natasa, Weiss, H. Markus, Otto, Heike, Fink, Martin, Röhn, Till A.

المصدر: Clinical and Translational Science ; volume 17, issue 2 ; ISSN 1752-8054 1752-8062

الوصف: LYS006 is a novel, highly potent and selective, new‐generation leukotriene A4 hydrolase (LTA4H) inhibitor in clinical development for the treatment of neutrophil‐driven inflammatory diseases. We describe the complex pharmacokinetic to pharmacodynamic (PD) relationship in blood, plasma, and skin of LYS006‐treated nonclinical species and healthy human participants. In a randomized first in human study, participants were exposed to single ascending doses up to 100 mg and multiple ascending doses up to 80 mg b.i.d.. LYS006 showed rapid absorption, overall dose proportional plasma exposure and nonlinear blood to plasma distribution caused by saturable target binding. The compound efficiently inhibited LTB4 production in human blood and skin blister cells, leading to greater than 90% predose target inhibition from day 1 after treatment initiation at doses of 20 mg b.i.d. and above. Slow re‐distribution from target expressing cells resulted in a long terminal half‐life and a long‐lasting PD effect in ex vivo stimulated blood and skin cells despite low plasma exposures. LYS006 was well‐tolerated and demonstrated a favorable safety profile up to highest doses tested, without any dose‐limiting toxicity. This supported further clinical development in phase II studies in predominantly neutrophil‐driven inflammatory conditions, such as hidradenitis suppurativa, inflammatory acne, and ulcerative colitis.

الإتاحة: https://doi.org/10.1111/cts.13724Test

المؤلفون: Eynard, Benoit, Bachmann, Pascale, Le-Loch, Sébastien, Picard, Damien, Guérin, Jean-Dominique, Bricogne, Matthieu, Reyes, Tatiana

المساهمون: Roberval (Roberval), Université de Technologie de Compiègne (UTC), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom Paris (IMT)-Institut Mines-Télécom Paris (IMT)-NANTES UNIVERSITÉ - École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ), Laboratoire d'Automatique, de Mécanique et d'Informatique industrielles et Humaines - UMR 8201 (LAMIH), Centre National de la Recherche Scientifique (CNRS)-Université Polytechnique Hauts-de-France (UPHF)-INSA Institut National des Sciences Appliquées Hauts-de-France (INSA Hauts-De-France), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA), INSA Institut National des Sciences Appliquées Hauts-de-France (INSA Hauts-De-France), Institut National des Sciences Appliquées (INSA), Université de Technologie de Troyes (UTT)

المصدر: Proceedings of the Design Society ; 24th International Conference on Engineering Design - ICED 2023 ; https://hal.utc.fr/hal-04280625Test ; 24th International Conference on Engineering Design - ICED 2023, Jul 2023, Bordeaux, France. pp.2145-2154, ⟨10.1017/pds.2023.215⟩

مصطلحات موضوعية: Design education, Ecodesign, Hybrid Learning, Product Developement, Systems Engineering, [SPI]Engineering Sciences [physics], [SHS.EDU]Humanities and Social Sciences/Education

جغرافية الموضوع: Bordeaux, France

الوصف: International audience ; During coronavirus time, academic organisations and education institutions have been faced to amazing and radical changes from one day to the other of their teaching contexts, practices, materials and standards and so on. Due to pandemic, in many countries professors, teachers, educators have been obliged to switch on remote education and teaching models with numerous virtual and digital solutions that at the beginning were more or less efficient and professional based. The paper will present a experiment feedback for large hybridation of technology and engineering curriculum for bachelor degree in French higher education system. The educational content and platform has been developed by the consortium of 14 different universities and higher education institutions. In the global topics covered by the project, a specific focus will be given in the paper on subject dealing with engineering design, systems engineering and sustainanibility.

العلاقة: hal-04280625; https://hal.utc.fr/hal-04280625Test

الإتاحة: https://doi.org/10.1017/pds.2023.215Test
https://hal.utc.fr/hal-04280625Test

المؤلفون: Bonnet, Manon, Guédon, Gérald, Bertolino, Sandro, Harmange, Clément, Pagano, Alain, Picard, Damien, Pays, Olivier

المساهمون: Biodiversité dans l’Anthropocène - Dynamique, Fonction & Gestion (BIODIVAG), Université d'Angers (UA)

المصدر: EISSN: 1989-8649 ; Management of Biological Invasions ; https://univ-angers.hal.science/hal-04352434Test ; Management of Biological Invasions, 2023, 14 (4), pp.625 - 640. ⟨10.3391/mbi.2023.14.4.04⟩

مصطلحات موضوعية: alien species, species control, capture, control program, volunteers, Myocastor coypus, Ondatra zibethicus, [SDE]Environmental Sciences

الوصف: Invasive alien species (IAS), including aquatic invasive alien rodents (AIAR), cause extensive damage to ecosystems with significant economic, human health, and environmental concerns. In France, AIAR populations are well established, and a permanent control programme has been set up in several areas to reduce their impact. While some studies have reported the results of AIAR control activities, detailed information on current management strategies and how control activities are implemented in the field is lacking. This study evaluates the implementation of the management plan and control activities of AIAR in France regarding (i) problem definition, feasibility and objectives, (ii) planning from action plan, organization, funding and methods, (iii) field implementation from spatial prioritisation and personnel and (iv) monitoring and evaluation. Our study reveals that in France, (i) local and regional institutions mainly manage control activities primarily through volunteers and (ii) national and regional management plans on AIAR controls are missing. We elaborate on several actions that can help local and regional entities in improving their control programme, including zonation for priority actions, development of performance indicators of control activities, engagement of volunteers, and scientific monitoring of AIAR populations.

العلاقة: hal-04352434; https://univ-angers.hal.science/hal-04352434Test; https://univ-angers.hal.science/hal-04352434/documentTest; https://univ-angers.hal.science/hal-04352434/file/MBI_2023_Bonnet_etal.pdfTest

الإتاحة: https://doi.org/10.3391/mbi.2023.14.4.04Test
https://univ-angers.hal.science/hal-04352434Test
https://univ-angers.hal.science/hal-04352434/documentTest
https://univ-angers.hal.science/hal-04352434/file/MBI_2023_Bonnet_etal.pdfTest

المؤلفون: Pays, Olivier, Bonnet, Manon, Marchand, Ewen, Harmange, Clément, Bertolino, Sandro, Pagano, Alain, Picard, Damien, Grillo, Xavier, Grimault-Frémy, Antonin

المصدر: Sustainability (2071-1050); Mar2024, Vol. 16 Issue 5, p1970, 16p

مستخلص: Managing invasive alien species (IAS) is a critical issue for many countries to preserve native biodiversity, ecosystem services and human well-being. In western France, we analyzed data of captures of aquatic invasive alien rodents (AIARs), the coypu and muskrat, by the local permanent control program from 2007 to 2022 across 26 municipalities encompassing 631 km². We found that control activities removed up to 10.3 AIARs per km² annually. The number of coypus removed per trapper per year increased by 220%, whereas it decreased by 85% for muskrats. The number of trappers increased from 2007 to 2014, peaking at 70, and then decreased by 50% in 2022. The number of AIARs captured per trapper per year increased with the density of ponds. The number of coypus captured per year decreased with an increasing amount of woodland per municipality, whereas it increased with road density. Finally, other tested landscape variables did not affect the number of AIARs removed per trapper per year. Our results are discussed in the context of control activities implemented against IAS in other countries. We advocate for stakeholders to assess whether control activities against AIARs effectively mitigate the impacts on social-ecological systems in France. [ABSTRACT FROM AUTHOR]

: Copyright of Sustainability (2071-1050) is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Gauffre, Bertrand, Boissinot, Alexandre, Quiquempois, Vincent, Leblois, Raphael, Grillet, Pierre, Morin, Sophie, Picard, Damien, Ribout, Cécile, Lourdais, Olivier

المساهمون: School of Biological Sciences Clayton, Monash University Clayton, Plantes et systèmes de culture horticoles (PSH), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre d'Études Biologiques de Chizé - UMR 7372 (CEBC), La Rochelle Université (ULR)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Réserve Naturelle Régionale du Bocage des Antonins France, Office français de la biodiversité (OFB), Département de Biologie UFR Sciences - Université d'Angers France, Université d'Angers (UA), ANR-16-CE02-0008,GenoSpace,Nouveaux outils statistiques pour l'analyse spatiale des données génétiques(2016)

المصدر: ISSN: 0962-1083.

مصطلحات موضوعية: demographic inferences, dispersal, genetic diversity, landscape genetics, microsatellites, Triturus marmoratus, [SDE]Environmental Sciences

الوصف: International audience ; Recent agricultural intensification threatens global biodiversity with amphibians being one of the most impacted groups. Because of their biphasic life cycle, amphibians are particularly vulnerable to habitat loss and fragmentation that often result in small, isolated populations and loss of genetic diversity. Here, we studied how landscape heterogeneity affects genetic diversity, gene flow and demographic parameters in the marbled newt, Triturus marmoratus, over a hedgerow network landscape in Western France. While the northern part of the study area consists of preserved hedged farm-land, the southern part was more profoundly converted for intensive arable crops production after WWII. Based on 67 sampled ponds and 10 microsatellite loci, we characterized regional population genetic structure and evaluated the correlation between landscape variables and (i) local genetic diversity using mixed models and (ii) genetic distance using multiple regression methods and commonality analysis. We identified a single genetic population characterized by a spatially heterogeneous isolation- by- distance pattern. Pond density in the surrounding landscape positively affected local genetic diversity while arable crop land cover negatively affected gene flow and connectivity. We used demographic inferences to quantitatively assess dif-ferences in effective population density and dispersal between the contrasted land-scapes characterizing the northern and southern parts of the study area. Altogether, results suggest recent land conversion affected T. marmoratus through reduction in both effective population density and dispersal due to habitat loss and reduced connectivity.

العلاقة: hal-03436626; https://hal.science/hal-03436626Test; https://hal.science/hal-03436626/documentTest; https://hal.science/hal-03436626/file/211008_NewtPaperFinal-Revision.pdfTest; WOS: 000715352100001

الإتاحة: https://doi.org/10.1111/mec.16236Test
https://hal.science/hal-03436626Test
https://hal.science/hal-03436626/documentTest
https://hal.science/hal-03436626/file/211008_NewtPaperFinal-Revision.pdfTest

المؤلفون: Testud, Guillaume, Canonne, Coline, Le Petitcorps, Quentin, Picard, Damien, Lengagne, Thierry, Labarraque, Dorothée, Miaud, Claude

المساهمون: Centre d’Ecologie Fonctionnelle et Evolutive (CEFE), Université Paul-Valéry - Montpellier 3 (UPVM)-École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD France-Sud )-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Montpellier, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Université de Montpellier (UM), Egis Structures et Environnement, Biodiversité dans l’Anthropocène - Dynamique, Fonction & Gestion (BIODIVAG), Université d'Angers (UA), Équipe 4 - Écophysiologie, Comportement, Conservation (E2C), Laboratoire d'Ecologie des Hydrosystèmes Naturels et Anthropisés (LEHNA), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-École Nationale des Travaux Publics de l'État (ENTPE)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-École Nationale des Travaux Publics de l'État (ENTPE)-Centre National de la Recherche Scientifique (CNRS)

المصدر: ISSN: 2296-701X ; Frontiers in Ecology and Evolution ; https://hal.science/hal-04172284Test ; Frontiers in Ecology and Evolution, 2022, 10, ⟨10.3389/fevo.2022.958655⟩.

مصطلحات موضوعية: linear transport infrastructure, amphibian, wildlife passage, acoustic enrichment, multi-state capture–recapture model, [SDE.IE]Environmental Sciences/Environmental Engineering

الوصف: International audience ; Linear transport infrastructure can alter the viability of populations and wildlife passages are used to mitigate their impacts. The assessment of their outcomes is often limited to recording the use of the tunnels by a focal species. For amphibians, the effectiveness of tunnels is poorly evaluated with little information about whether certain features encourage individuals that may be reluctant to pass through tunnels. One study showed that acoustic enrichment with anuran calls can increase the crossing of tunnels by newts. This study recorded the behavior of three European amphibian species in three tunnels, tracking them with PIT tags and detection with four RFID antennas installed on the floor of the tunnels. We tested (1) the effectiveness of the antennas in detecting the species, (2) the effect of the length of the tunnels, and (3) the effect of acoustic enrichment. Using a multi-state capture–recapture model, we evaluated the probability of an individual advancing between the tunnel sections. The effectiveness of the antennas varied according to species, higher for Urodela species than for Anuran species. Several types of paths were detected (constant and varying speeds, halt, and back-and-forth movements). The fire salamander and the great crested newt individuals exhibited a similar variety of movements in the tunnels (21 and 40 m length). Triturus cristatus made similar movements in the tunnels with and without acoustic enrichment. In water frogs, all the individuals ( n = 16) made a complete crossing in the tunnel with enrichment vs. 75% ( n = 71) in the tunnel without enrichment. In T. cristatus , the probability of going forward at the entrance of the tunnel was 18% higher with enrichment in one tunnel. No significant effect of acoustic enrichment was observed in two others tunnels for this species. In Pelophylax esculentus , this probability was 78% higher in the tunnel with enrichment. This multi-antenna RFID system was able to provide valuable information on the behavior ...

العلاقة: hal-04172284; https://hal.science/hal-04172284Test; https://hal.science/hal-04172284/documentTest; https://hal.science/hal-04172284/file/Testud%20et%20al.%202022.pdfTest

الإتاحة: https://doi.org/10.3389/fevo.2022.958655Test
https://hal.science/hal-04172284Test
https://hal.science/hal-04172284/documentTest
https://hal.science/hal-04172284/file/Testud%20et%20al.%202022.pdfTest

المؤلفون: de Solan, Thomas, Théry, Marc, Picard, Damien, Crochet, Pierre-André, David, Patrice, Secondi, Jean

المساهمون: Centre d’Ecologie Fonctionnelle et Evolutive (CEFE), Université Paul-Valéry - Montpellier 3 (UPVM)-École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD France-Sud )-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Montpellier, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Université de Montpellier (UM), Mécanismes Adaptatifs et Evolution (MECADEV), Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS), Université d'Angers (UA), Biodiversité dans l’Anthropocène - Dynamique, Fonction & Gestion (BIODIVAG), Laboratoire d'Ecologie des Hydrosystèmes Naturels et Anthropisés (LEHNA), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-École Nationale des Travaux Publics de l'État (ENTPE)-Centre National de la Recherche Scientifique (CNRS), ANR-11-BSV7-0001,SENSHYBLE,Ecologie Sensorielle des Zones d'Hybridation en Environnement Lentique(2011)

المصدر: ISSN: 1010-061X.

مصطلحات موضوعية: Lissotriton, crypsis, natural selection, reproductive character displacement, sexual, sexual selection, [SDV.BA.ZV]Life Sciences [q-bio]/Animal biology/Vertebrate Zoology, [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]

الوصف: International audience ; Coexistence with related species poses evolutionary challenges to which populations may react in diverse ways. When exposed to similar environments, sympatric populations of two species may adopt similar phenotypic trait values. However, selection may also favour trait divergence as a way to reduce competition for resources or mates. The characteristics of external body parts, such as coloration and external morphology, are involved to varying degrees in intraspecific signalling as well as in the adaptation to the environment and consequently may be diversely affected by interspecific interactions in sympatry. Here, we studied the effect of sympatry on various colour and morphological traits in males and females of two related newt species Lissotriton helveticus and L. vulgaris. Importantly, we did not only estimate how raw trait differences between species respond to sympatry, but also the marginal responses after controlling for environmental variation. We found that dorsal and caudal coloration converged in sympatry, likely reflecting their role in adaptation to local environments, especially concealment from predators. In contrast, aspects of male and female ventral coloration, which harbours sexual signals in both species, diverged in sympatry. This divergence may reduce opportunities for interspecific sexual interactions and the associated loss of energy, suggesting reproductive character displacement (RCD). Our study emphasizes the contrasting patterns of traits involved in different functions and calls for the need to consider this diversity in evolutionary studies.

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35146835; hal-03921057; https://hal.science/hal-03921057Test; https://hal.science/hal-03921057/documentTest; https://hal.science/hal-03921057/file/2022%20triton%20Thomas%20de%20Solan_finalise_libre_de_droit.pdfTest; PUBMED: 35146835; WOS: 000765873400001

الإتاحة: https://doi.org/10.1111/jeb.13985Test
https://hal.science/hal-03921057Test
https://hal.science/hal-03921057/documentTest
https://hal.science/hal-03921057/file/2022%20triton%20Thomas%20de%20Solan_finalise_libre_de_droit.pdfTest

المؤلفون: Testud, Guillaume, Fauconnier, Clément, Labarraque, Dorothée, Lengagne, Thierry, Le Petitcorps, Quentin, Picard, Damien, Miaud, Claude

المساهمون: Centre d’Ecologie Fonctionnelle et Evolutive (CEFE), Université Paul-Valéry - Montpellier 3 (UPVM)-École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD France-Sud )-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Egis Structures et Environnement, Laboratoire d'Ecologie des Hydrosystèmes Naturels et Anthropisés (LEHNA), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-École Nationale des Travaux Publics de l'État (ENTPE)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Cogitamus = Cogitamus Laboratory

المصدر: ISSN: 2351-9894 ; Global Ecology and Conservation ; https://univ-lyon1.hal.science/hal-02975324Test ; Global Ecology and Conservation, 2020, 24, pp.e01252. ⟨10.1016/j.gecco.2020.e01252⟩.

مصطلحات موضوعية: Transport infrastructure Tunnels Mitigation evaluation Acoustic orientation, Transport infrastructure, Tunnels, Mitigation evaluation, Acoustic orientation, [SDE.BE]Environmental Sciences/Biodiversity and Ecology

الوصف: International audience ; Linear transport infrastructure can impact wildlife directly or indirectly, and amphibians are particularly affected. In some cases, mitigation measures e such as tunnels below the linear transport infrastructure e are implemented, but an evaluation of their effectiveness is often lacking, especially for small animals such as amphibians. Few studies have focused on crossing behaviour in underpasses, yet this information may be crucial to improve mitigation measures. In this study, we conducted experiments in three tunnels below a high-speed railway with individually marked amphibians (great crested newt Triturus cristatus, marbled newt Triturus marmoratus, alpine newt Ichthyosaura alpestris, fire sala- mander Salamandra salamandra, spined toad Bufo spinosus, agile frog Rana dalmatina and edible/pool frog Pelophylax kl. esculentus/lessonae) which were released at the entrance of tunnels varying in length. Behaviours (e.g. completed crossing, U-turn, not moving, and stay) and crossing speed were recorded. R. dalmatina, S. salamandra and T. cristatus (but not B. spinosus) exhibited crossing rate differences between tunnels 21 m and 40 m in length. More individuals performed “complete crossing” through the shorter tunnel. The crossing speed of the S. salamandra and T. cristatus did not differ between the tunnels of different lengths. In a second experiment, we evaluated the effect of acoustic enrichment on the crossing behaviour of one frog and three newt species by broadcasting a soundtrack of mating calls of syntopic anuran species in the tunnels. Pelophylax kl exhibited a large in- crease in complete crossings and in speed. T. cristatus showed an increase in tunnel complete crossings (but not speed) in one of the acoustically enhanced tunnels. These results indicate that acoustic enrichment can improve the crossing of underpasses. This low cost and easily implementable method could help to inform the design of wildlife passages as mitigation measures for impacted amphibian populations, ...

العلاقة: hal-02975324; https://univ-lyon1.hal.science/hal-02975324Test; https://univ-lyon1.hal.science/hal-02975324/documentTest; https://univ-lyon1.hal.science/hal-02975324/file/article4.pdfTest

الإتاحة: https://doi.org/10.1016/j.gecco.2020.e01252Test
https://univ-lyon1.hal.science/hal-02975324Test
https://univ-lyon1.hal.science/hal-02975324/documentTest
https://univ-lyon1.hal.science/hal-02975324/file/article4.pdfTest

المؤلفون: Laferrière, Alex, Cimmino, Massimo, Picard, Damien, Helsen, Lieve

مصطلحات موضوعية: 2100 Génie mécanique, 2107 Modélisation, simulation et méthodes des éléments finis

الوصف: This paper presents the development and validation of a full-time-scale semi-analytical bore field simulation model. The model allows for the simulation of bore fields comprised of arbitrarily positioned boreholes while accounting for both short-term transient thermal effects within the boreholes and long-term thermal interactions in the bore field. The g-function of the bore field, obtained from the finite line source solution, is corrected to account for the cylindrical geometry of the boreholes and coupled to a thermal resistances and capacitances model of the borehole interior, thereby extending the scope of g-functions to short time scales. Additionally, an improved load aggregation scheme for ground thermal response calculations allows the model to be used with variable simulation time steps. The complete model is validated using a combination of analytical, experimental and field monitored data to verify both its short-term and long-term behaviour. The model is implemented using the Modelica language as part of an implementation in the open-source buildings simulation library IBPSA.

وصف الملف: text

العلاقة: https://publications.polymtl.ca/5507/7/2020_Laferri%C3%A8re_Development_validation_full-time-scale_semi-analytical_model.pdfTest; Laferrière, A., Cimmino, M., Picard, D., & Helsen, L. (2020). Development and validation of a full-time-scale semi-analytical model for the short- and long-term simulation of vertical geothermal bore fields. Geothermics, 86.

الإتاحة: https://doi.org/10.1016/j.geothermics.2019.101788Test
https://publications.polymtl.ca/5507Test/
https://publications.polymtl.ca/5507/7/2020_Laferri%C3%A8re_Development_validation_full-time-scale_semi-analytical_model.pdfTest

المؤلفون: Carballido, José M., Regairaz, Camille, Rauld, Celine, Raad, Layla, Picard, Damien, Kammüller, Michael

المصدر: Frontiers in Immunology ; volume 11 ; ISSN 1664-3224

الإتاحة: https://doi.org/10.3389/fimmu.2020.00472Test