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31صورة
المؤلفون: Lok Hang Chan, Peihan Wang, Shatha Abuhammad, Lydia Rui Jia Lim, Joseph Cursons, Karen E. Sheppard, David L. Goode
مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Developmental Biology, Marine Biology, Cancer, Hematology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, promising new treatments, length mrna sequencing, important downstream component, 6 inhibitor resistance, 6 inhibitor palbociclib, gene expression profiles, prmt5 inhibitor gsk3326595, findings indicate cdk4, dependent kinases 4, regulate alternative splicing, mrna splicing induced, differential gene expression, 6 inhibition result, although prmt5 inhibition, melanoma p, gene expression, alternative splicing
الإتاحة: https://doi.org/10.1371/journal.pone.0292278.s016Test
https://figshare.com/articles/figure/Significance_of_gene_sets_detected_accommodate_all_samples_in_both_differentially_expressed_and_spliced_genes_/24489863Test -
32صورة
المؤلفون: Lok Hang Chan, Peihan Wang, Shatha Abuhammad, Lydia Rui Jia Lim, Joseph Cursons, Karen E. Sheppard, David L. Goode
مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Developmental Biology, Marine Biology, Cancer, Hematology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, promising new treatments, length mrna sequencing, important downstream component, 6 inhibitor resistance, 6 inhibitor palbociclib, gene expression profiles, prmt5 inhibitor gsk3326595, findings indicate cdk4, dependent kinases 4, regulate alternative splicing, mrna splicing induced, differential gene expression, 6 inhibition result, although prmt5 inhibition, melanoma p, gene expression, alternative splicing
الإتاحة: https://doi.org/10.1371/journal.pone.0292278.s005Test
https://figshare.com/articles/figure/Schematic_of_the_single_contrast_analyses_solid_lines_comparing_each_treatment_to_the_control_and_multi-contrast_analyses_dashed_lines_comparing_differentially_expressed_genes_or_differentially_spliced_events_obtained_from_the_single_contra/24489827Test -
33صورة
المؤلفون: Lok Hang Chan, Peihan Wang, Shatha Abuhammad, Lydia Rui Jia Lim, Joseph Cursons, Karen E. Sheppard, David L. Goode
مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Developmental Biology, Marine Biology, Cancer, Hematology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, promising new treatments, length mrna sequencing, important downstream component, 6 inhibitor resistance, 6 inhibitor palbociclib, gene expression profiles, prmt5 inhibitor gsk3326595, findings indicate cdk4, dependent kinases 4, regulate alternative splicing, mrna splicing induced, differential gene expression, 6 inhibition result, although prmt5 inhibition, melanoma p, gene expression, alternative splicing
الإتاحة: https://doi.org/10.1371/journal.pone.0292278.s013Test
https://figshare.com/articles/figure/Number_of_differentially_spliced_events_and_differentially_spliced_genes_across_treatments_with_the_p-value_0_05_threshold_/24489854Test -
34صورة
المؤلفون: Lok Hang Chan, Peihan Wang, Shatha Abuhammad, Lydia Rui Jia Lim, Joseph Cursons, Karen E. Sheppard, David L. Goode
مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Developmental Biology, Marine Biology, Cancer, Hematology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, promising new treatments, length mrna sequencing, important downstream component, 6 inhibitor resistance, 6 inhibitor palbociclib, gene expression profiles, prmt5 inhibitor gsk3326595, findings indicate cdk4, dependent kinases 4, regulate alternative splicing, mrna splicing induced, differential gene expression, 6 inhibition result, although prmt5 inhibition, melanoma p, gene expression, alternative splicing
الإتاحة: https://doi.org/10.1371/journal.pone.0292278.g003Test
https://figshare.com/articles/figure/Differential_splicing_in_response_to_CDK4_6_and_PRMT5_inhibition_/24489875Test -
35صورة
المؤلفون: Lok Hang Chan, Peihan Wang, Shatha Abuhammad, Lydia Rui Jia Lim, Joseph Cursons, Karen E. Sheppard, David L. Goode
مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Developmental Biology, Marine Biology, Cancer, Hematology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, promising new treatments, length mrna sequencing, important downstream component, 6 inhibitor resistance, 6 inhibitor palbociclib, gene expression profiles, prmt5 inhibitor gsk3326595, findings indicate cdk4, dependent kinases 4, regulate alternative splicing, mrna splicing induced, differential gene expression, 6 inhibition result, although prmt5 inhibition, melanoma p, gene expression, alternative splicing
الإتاحة: https://doi.org/10.1371/journal.pone.0292278.g001Test
https://figshare.com/articles/figure/Prolonged_CDK4_6_inhibition_response_of_gene_expression_and_splicing_in_A375_and_CHL1_/24489866Test -
36صورة
المؤلفون: Lok Hang Chan, Peihan Wang, Shatha Abuhammad, Lydia Rui Jia Lim, Joseph Cursons, Karen E. Sheppard, David L. Goode
مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Developmental Biology, Marine Biology, Cancer, Hematology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, promising new treatments, length mrna sequencing, important downstream component, 6 inhibitor resistance, 6 inhibitor palbociclib, gene expression profiles, prmt5 inhibitor gsk3326595, findings indicate cdk4, dependent kinases 4, regulate alternative splicing, mrna splicing induced, differential gene expression, 6 inhibition result, although prmt5 inhibition, melanoma p, gene expression, alternative splicing
الإتاحة: https://doi.org/10.1371/journal.pone.0292278.g002Test
https://figshare.com/articles/figure/Differential_gene_expression_in_response_to_CDK4_6_and_PRMT5_inhibition_/24489872Test -
37صورة
المؤلفون: Lok Hang Chan, Peihan Wang, Shatha Abuhammad, Lydia Rui Jia Lim, Joseph Cursons, Karen E. Sheppard, David L. Goode
مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Developmental Biology, Marine Biology, Cancer, Hematology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, promising new treatments, length mrna sequencing, important downstream component, 6 inhibitor resistance, 6 inhibitor palbociclib, gene expression profiles, prmt5 inhibitor gsk3326595, findings indicate cdk4, dependent kinases 4, regulate alternative splicing, mrna splicing induced, differential gene expression, 6 inhibition result, although prmt5 inhibition, melanoma p, gene expression, alternative splicing
الإتاحة: https://doi.org/10.1371/journal.pone.0292278.g004Test
https://figshare.com/articles/figure/Functional_responses_in_differentially_expressed_and_spliced_genes_/24489878Test -
38صورة
المؤلفون: Yingjiao Ju, Chengji Jin, Shan Chen, Jie Wang, Cuidan Li, Xiaotong Wang, Peihan Wang, Liya Yue, Xiaoyuan Jiang, Bahetibieke Tuohetaerbaike, Ying Li, Yongjie Sheng, Wushou’er Qimanguli, Jing Wang, Fei Chen
مصطلحات موضوعية: Clinical Microbiology, Medical Bacteriology, Medical Infection Agents (incl. Prions), Medical Virology, tuberculosis, smear-negative pulmonary tuberculosis, smear-positive pulmonary tuberculosis, proteomics, antigen-presenting cells
الإتاحة: https://doi.org/10.3389/fcimb.2023.1240516.s002Test
https://figshare.com/articles/figure/Image_2_Proteomic_analyses_of_smear-positive_negative_tuberculosis_patients_uncover_differential_antigen-presenting_cell_activation_and_lipid_metabolism_tif/24313459Test -
39
المؤلفون: Yingjiao Ju, Chengji Jin, Shan Chen, Jie Wang, Cuidan Li, Xiaotong Wang, Peihan Wang, Liya Yue, Xiaoyuan Jiang, Bahetibieke Tuohetaerbaike, Ying Li, Yongjie Sheng, Wushou’er Qimanguli, Jing Wang, Fei Chen
مصطلحات موضوعية: Clinical Microbiology, Medical Bacteriology, Medical Infection Agents (incl. Prions), Medical Virology, tuberculosis, smear-negative pulmonary tuberculosis, smear-positive pulmonary tuberculosis, proteomics, antigen-presenting cells
الإتاحة: https://doi.org/10.3389/fcimb.2023.1240516.s006Test
https://figshare.com/articles/dataset/Table_2_Proteomic_analyses_of_smear-positive_negative_tuberculosis_patients_uncover_differential_antigen-presenting_cell_activation_and_lipid_metabolism_xlsx/24313474Test -
40صورة
المؤلفون: Lok Hang Chan, Peihan Wang, Shatha Abuhammad, Lydia Rui Jia Lim, Joseph Cursons, Karen E. Sheppard, David L. Goode
مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Developmental Biology, Marine Biology, Cancer, Hematology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, promising new treatments, length mrna sequencing, important downstream component, 6 inhibitor resistance, 6 inhibitor palbociclib, gene expression profiles, prmt5 inhibitor gsk3326595, findings indicate cdk4, dependent kinases 4, regulate alternative splicing, mrna splicing induced, differential gene expression, 6 inhibition result, although prmt5 inhibition, melanoma p, gene expression, alternative splicing
الإتاحة: https://doi.org/10.1371/journal.pone.0292278.s012Test
https://figshare.com/articles/figure/PCR_products_showing_the_expression_patterns_of_MDM4-FL_and_MDM4-SL_mRNA_in_CHL1_and_A375_/24489848Test