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1دورية أكاديمية
المؤلفون: María Nieves Cabrera-Martín, Pedro Nespral, Maria Valles-Salgado, Pablo Bascuñana, Cristina Delgado-Alonso, Alfonso Delgado-Álvarez, Lucía Fernández-Romero, Juan Ignacio López-Carbonero, María Díez-Cirarda, María José Gil-Moreno, Jorge Matías-Guiu, Jordi A. Matias-Guiu
المصدر: Frontiers in Psychology, Vol 14 (2023)
مصطلحات موضوعية: Alzheimer’s disease, frontotemporal dementia, neuropsychological assessment, Addenbrooke’s cognitive examination, positron emission tomography, Psychology, BF1-990
الوصف: IntroductionThe Addenbrooke’s Cognitive Examination III (ACE-III) is a brief test useful for neuropsychological assessment. Several studies have validated the test for the diagnosis of Alzheimer’s disease (AD) and frontotemporal dementia (FTD). In this study, we aimed to examine the metabolic correlates associated with the performance of ACE-III in AD and behavioral variant FTD.MethodsWe enrolled 300 participants in a cross-sectional study, including 180 patients with AD, 60 with behavioral FTD (bvFTD), and 60 controls. An 18F-Fluorodeoxyglucose positron emission tomography study was performed in all cases. Correlation between the ACE-III and its domains (attention, memory, fluency, language, and visuospatial) with the brain metabolism was estimated.ResultsThe ACE-III showed distinct neural correlates in bvFTD and AD, effectively capturing the most relevant regions involved in these disorders. Neural correlates differed for each domain, especially in the case of bvFTD. Lower ACE-III scores were associated with more advanced stages in both disorders. The ACE-III exhibited high discrimination between bvFTD vs. HC, and between AD vs. HC. Additionally, it was sensitive to detect hypometabolism in brain regions associated with bvFTD and AD.ConclusionOur study contributes to the knowledge of the brain regions associated with ACE-III, thereby facilitating its interpretation, and highlighting its suitability for screening and monitoring. This study provides further validation of ACE-III in the context of AD and FTD.
وصف الملف: electronic resource
العلاقة: https://www.frontiersin.org/articles/10.3389/fpsyg.2023.1273608/fullTest; https://doaj.org/toc/1664-1078Test
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2دورية أكاديمية
المؤلفون: Isea, Anna E. Berardinelli, Navas, Maglen Katherine Meneses, Torres, Pedro Nespral, Fernández, Patricia Romero, Oñate, Paloma Daudén, Domingo, Gonzalo Cuesta, Carrero, María Fernanda Ollarves, Rodríguez, Ana María Crespo, Martín, María Nieves Cabrera
المصدر: Revista Española de Medicina Nuclear e Imagen Molecular ; volume 42, page S59 ; ISSN 2253-654X
مصطلحات موضوعية: Radiology, Nuclear Medicine and imaging
الإتاحة: https://doi.org/10.1016/s2253-654xTest(23)00183-x
https://api.elsevier.com/content/article/PII:S2253654X2300183X?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2253654X2300183X?httpAccept=text/plainTest -
3دورية أكاديمية
المؤلفون: Fernández, Patricia Romero, Navas, Maglen Katherine Meneses, Carrero, Maria Fernanda Ollarves, Torres, Pedro Nespral, Domingo, Gonzalo Cuesta, Oñate, Paloma Dauden, Isea, Anna E. Berardinelli, Caro, Rosa Couto, Martín, Maria Nieves Cabrera
المصدر: Revista Española de Medicina Nuclear e Imagen Molecular ; volume 42, page S282 ; ISSN 2253-654X
مصطلحات موضوعية: Radiology, Nuclear Medicine and imaging
الإتاحة: https://doi.org/10.1016/s2253-654xTest(23)00406-7
https://api.elsevier.com/content/article/PII:S2253654X23004067?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2253654X23004067?httpAccept=text/plainTest -
4دورية أكاديمية
المؤلفون: Katherine Meneses Navas, Maglen, Romero Fernández, Patricia, Caro, Rosa Couto, Fernanda Ollarves Carrero, María, Torres, Pedro Nespral, Domingo, Gonzalo Cuesta, Daudén Oñate, Paloma, Isea, Anna Elvira Berardinelli, Martín, Maria Nieves Cabrera
المصدر: Revista Española de Medicina Nuclear e Imagen Molecular ; volume 42, page S125 ; ISSN 2253-654X
مصطلحات موضوعية: Radiology, Nuclear Medicine and imaging
الإتاحة: https://doi.org/10.1016/s2253-654xTest(23)00249-4
https://api.elsevier.com/content/article/PII:S2253654X23002494?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2253654X23002494?httpAccept=text/plainTest -
5دورية أكاديمية
المؤلفون: Domingo, Gonzalo Cuesta, Rey, Cristina Rodríguez, Candil, Aida Ortega, Carrizal, Rubén Cano, Oñate, Paloma Dauden, Torres, Pedro Nespral, Navas, Maglen Katherine Meneses, Fernández, Patricia Romero, Martín, María Nieves Cabrera
المصدر: Revista Española de Medicina Nuclear e Imagen Molecular ; volume 42, page S42 ; ISSN 2253-654X
مصطلحات موضوعية: Radiology, Nuclear Medicine and imaging
الإتاحة: https://doi.org/10.1016/s2253-654xTest(23)00166-x
https://api.elsevier.com/content/article/PII:S2253654X2300166X?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2253654X2300166X?httpAccept=text/plainTest -
6دورية أكاديمية
المؤلفون: Carrero, María Fernanda Ollarves, Navas, Maglen Meneses, Fernández, Patricia Romero, Torres, Pedro Nespral, Olivero, Carlos Fraile, Martín, Elena Fernández, Domingo, Gonzalo Cuesta, Caro, Rosa Couto, Martín, Maria Nieves Cabrera
المصدر: Revista Española de Medicina Nuclear e Imagen Molecular ; volume 42, page S200-S201 ; ISSN 2253-654X
مصطلحات موضوعية: Radiology, Nuclear Medicine and imaging
الإتاحة: https://doi.org/10.1016/s2253-654xTest(23)00324-4
https://api.elsevier.com/content/article/PII:S2253654X23003244?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2253654X23003244?httpAccept=text/plainTest -
7دورية أكاديمية
المؤلفون: Torres, Pedro Nespral, Almarcha, Pablo Bascuñana, Cano, Ana Delgado, Domingo, Gonzalo Cuesta, Fernández, Patricia Romero, Navas, Maglen Katherine Meneses, Matías-Guiu, Jordi A., Delgado, José Luis Carreras, Martín, María Nieves Cabrera
المصدر: Revista Española de Medicina Nuclear e Imagen Molecular ; volume 42, page S285 ; ISSN 2253-654X
مصطلحات موضوعية: Radiology, Nuclear Medicine and imaging
الإتاحة: https://doi.org/10.1016/s2253-654xTest(23)00409-2
https://api.elsevier.com/content/article/PII:S2253654X23004092?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2253654X23004092?httpAccept=text/plainTest -
8دورية أكاديمية
المؤلفون: Torres, Pedro Nespral, Almarcha, Pablo Bascuñana, Cano, Ana Delgado, Oñate, Paloma Daudén, Isea, Anna Elvira Berardinelli, Carrero, María Fernanda Ollarves, Matías-Guiu, Jordi A., Delgado, José Luis Carreras, Martín, María Nieves Cabrera
المصدر: Revista Española de Medicina Nuclear e Imagen Molecular ; volume 42, page S286 ; ISSN 2253-654X
مصطلحات موضوعية: Radiology, Nuclear Medicine and imaging
الإتاحة: https://doi.org/10.1016/s2253-654xTest(23)00410-9
https://api.elsevier.com/content/article/PII:S2253654X23004109?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2253654X23004109?httpAccept=text/plainTest -
9
المؤلفون: María Nieves Cabrera-Martín, Pedro Nespral, Maria Valles-Salgado, Pablo Bascuñana, Cristina Delgado-Alonso, Alfonso Delgado-Álvarez, Lucía Fernández-Romero, Juan Ignacio López-Carbonero, María Díez-Cirarda, María José Gil-Moreno, Jorge Matías-Guiu, Jordi A. Matias-Guiu
مصطلحات موضوعية: Applied Psychology, Clinical Psychology, Developmental and Educational Psychology, Neuroscience and Physiological Psychology, Organizational Behavioral Psychology, Personality, Social and Criminal Psychology, Gender Psychology, Health, Clinical and Counselling Psychology, Industrial and Organisational Psychology, Psychology not elsewhere classified, Psychology and Cognitive Sciences not elsewhere classified, Alzheimer’s disease, frontotemporal dementia, neuropsychological assessment, Addenbrooke’s cognitive examination, positron emission tomography
الوصف: Introduction The Addenbrooke’s Cognitive Examination III (ACE-III) is a brief test useful for neuropsychological assessment. Several studies have validated the test for the diagnosis of Alzheimer’s disease (AD) and frontotemporal dementia (FTD). In this study, we aimed to examine the metabolic correlates associated with the performance of ACE-III in AD and behavioral variant FTD. Methods We enrolled 300 participants in a cross-sectional study, including 180 patients with AD, 60 with behavioral FTD (bvFTD), and 60 controls. An 18 F-Fluorodeoxyglucose positron emission tomography study was performed in all cases. Correlation between the ACE-III and its domains (attention, memory, fluency, language, and visuospatial) with the brain metabolism was estimated. Results The ACE-III showed distinct neural correlates in bvFTD and AD, effectively capturing the most relevant regions involved in these disorders. Neural correlates differed for each domain, especially in the case of bvFTD. Lower ACE-III scores were associated with more advanced stages in both disorders. The ACE-III exhibited high discrimination between bvFTD vs. HC, and between AD vs. HC. Additionally, it was sensitive to detect hypometabolism in brain regions associated with bvFTD and AD. Conclusion Our study contributes to the knowledge of the brain regions associated with ACE-III, thereby facilitating its interpretation, and highlighting its suitability for screening and monitoring. This study provides further validation of ACE-III in the context of AD and FTD.
الإتاحة: https://doi.org/10.3389/fpsyg.2023.1273608.s003Test
https://figshare.com/articles/dataset/Table_2_FDG-PET-based_neural_correlates_of_Addenbrooke_s_cognitive_examination_III_scores_in_Alzheimer_s_disease_and_frontotemporal_degeneration_DOCX/24571504Test -
10صورة
المؤلفون: María Nieves Cabrera-Martín, Pedro Nespral, Maria Valles-Salgado, Pablo Bascuñana, Cristina Delgado-Alonso, Alfonso Delgado-Álvarez, Lucía Fernández-Romero, Juan Ignacio López-Carbonero, María Díez-Cirarda, María José Gil-Moreno, Jorge Matías-Guiu, Jordi A. Matias-Guiu
مصطلحات موضوعية: Applied Psychology, Clinical Psychology, Developmental and Educational Psychology, Neuroscience and Physiological Psychology, Organizational Behavioral Psychology, Personality, Social and Criminal Psychology, Gender Psychology, Health, Clinical and Counselling Psychology, Industrial and Organisational Psychology, Psychology not elsewhere classified, Psychology and Cognitive Sciences not elsewhere classified, Alzheimer’s disease, frontotemporal dementia, neuropsychological assessment, Addenbrooke’s cognitive examination, positron emission tomography
الوصف: Introduction The Addenbrooke’s Cognitive Examination III (ACE-III) is a brief test useful for neuropsychological assessment. Several studies have validated the test for the diagnosis of Alzheimer’s disease (AD) and frontotemporal dementia (FTD). In this study, we aimed to examine the metabolic correlates associated with the performance of ACE-III in AD and behavioral variant FTD. Methods We enrolled 300 participants in a cross-sectional study, including 180 patients with AD, 60 with behavioral FTD (bvFTD), and 60 controls. An 18 F-Fluorodeoxyglucose positron emission tomography study was performed in all cases. Correlation between the ACE-III and its domains (attention, memory, fluency, language, and visuospatial) with the brain metabolism was estimated. Results The ACE-III showed distinct neural correlates in bvFTD and AD, effectively capturing the most relevant regions involved in these disorders. Neural correlates differed for each domain, especially in the case of bvFTD. Lower ACE-III scores were associated with more advanced stages in both disorders. The ACE-III exhibited high discrimination between bvFTD vs. HC, and between AD vs. HC. Additionally, it was sensitive to detect hypometabolism in brain regions associated with bvFTD and AD. Conclusion Our study contributes to the knowledge of the brain regions associated with ACE-III, thereby facilitating its interpretation, and highlighting its suitability for screening and monitoring. This study provides further validation of ACE-III in the context of AD and FTD.
الإتاحة: https://doi.org/10.3389/fpsyg.2023.1273608.s001Test
https://figshare.com/articles/figure/Image_1_FDG-PET-based_neural_correlates_of_Addenbrooke_s_cognitive_examination_III_scores_in_Alzheimer_s_disease_and_frontotemporal_degeneration_JPEG/24571489Test