المؤلفون: Milani, Gregorio Paolo, Ronchi, Andrea, Agostoni, Carlo, Marchisio, Paola, Chidini, Giovanna, Pesenti, Nicola, Bellotti, Anita, Cugliari, Marco, Crimi, Riccardo, Fabiano, Valentina, Pietrasanta, Carlo, Pugni, Lorenza, Mosca, Fabio, Barachetti, Roberta, Pagliotta, Claudia, Gulden, Silvia, Risso, Francesco Maria, Colpani, Michael, Aversa, Salvatore, Tagliabue, Paolo, Cattaneo, Federico, Corbetta, Roberta, Ventura, Maria Luisa, Ghirardello, Stefano, De Lucia, Ilaria, Garofoli, Francesca, Mancini, Luca, Pattarino, Giulia Angela Carla, De Giacomo, Costantino, Barberi, Salvatore, Vernich, Mario, Veronelli, Elisabetta, Brazzoduro, Emanuela, Bottino, Ilaria, Varisco, Tiziana, Calzi, Patrizia, Porta, Alessandro, Alga, Paola, Cozzi, Laura, Lizzoli, Francesca, D’Antiga, Lorenzo, Mangili, Giovanna, Mazza, Angelo, Di Stasio, Fabiana, Marseglia, Gian Luigi, Mascolo, Amelia, Jankovic, Matea, Decembrino, Lidia, Pantaleo, Dario, Vimercati, Chiara, Faraguna, Martha Caterina, Cattaneo, Francesca, Lepri, Irene, Pogliani, Laura, Bevilacqua, Liana, Bernardo, Luca, Arrigoni, Sergio, Mercurio, Giuseppe, Paramithiotti, Costanza, Salvatici, Elisabetta, Banderali, Giuseppe, Podestà, Alberto Fabio, Dusi, Elisa, Vivaldo, Teresa, Bianchini, Sonia, Barera, Graziano, Del Barba, Paolo, Aracu, Claudia, Martinelli, Stefano, Proto, Alice, Fossati, Marco, Rossi, Lorella, Palumbo, Emilio, Odoni, Marta, Dalla Verde, Ilaria, Kantar, Ahmad, Sindico, Paola, Morandi, Grazia, Fasolato, Valeria, Viscogliosi, Germana, Managanelli, Nunzia Pia, Riva, Giuseppe, Tzialla, Chryssoula, Giacchero, Roberta, Sabatini, Caterina, Rossi, Elena, Ghitti, Cesare Antonio, Pacati, Ilaria, Badolato, Raffaele, Dotta, Laura, Meini, Antonella, Bresesti, Ilia, Francone, Antonio, Plebani, Anna Maria, Agosti, Massimo, Sala, Marco, Santucci, Simona, Cuzzupè, Chiara, Bellan, Cristina, Pontiggia, Federica, Romero, Alice, Perazzi, Chiara, Banfi, Anna, Zuccotti, Gianvincenzo, Lista, Gianluca

المساهمون: G.P. Milani, A. Ronchi, C. Agostoni, P. Marchisio, G. Chidini, N. Pesenti, A. Bellotti, M. Cugliari, R. Crimi, V. Fabiano, C. Pietrasanta, L. Pugni, F. Mosca, R. Barachetti, C. Pagliotta, S. Gulden, F.M. Risso, M. Colpani, S. Aversa, P. Tagliabue, F. Cattaneo, R. Corbetta, M.L. Ventura, S. Ghirardello, I. De Lucia, F. Garofoli, L. Mancini, G.A.C. Pattarino, C. De Giacomo, S. Barberi, M. Vernich, E. Veronelli, E. Brazzoduro, I. Bottino, T. Varisco, P. Calzi, A. Porta, P. Alga, L. Cozzi, F. Lizzoli, L. D’Antiga, G. Mangili, A. Mazza, F. Di Stasio, G.L. Marseglia, A. Mascolo, M. Jankovic, L. Decembrino, D. Pantaleo, C. Vimercati, M.C. Faraguna, I. Lepri, L. Pogliani, L. Bevilacqua, L. Bernardo, S. Arrigoni, G. Mercurio, C. Paramithiotti, E. Salvatici, G. Banderali, A.F. Podestà, E. Dusi, T. Vivaldo, S. Bianchini, G. Barera, P. Del Barba, C. Aracu, S. Martinelli, A. Proto, M. Fossati, L. Rossi, E. Palumbo, M. Odoni, I. Dalla Verde, A. Kantar, P. Sindico, G. Morandi, V. Fasolato, G. Viscogliosi, N.P. Managanelli, G. Riva, C. Tzialla, R. Giacchero, C. Sabatini, E. Rossi, C.A. Ghitti, I. Pacati, R. Badolato, L. Dotta, A. Meini, I. Bresesti, A. Francone, A.M. Plebani, M. Agosti, M. Sala, S. Santucci, C. Cuzzupè

مصطلحات موضوعية: Bronchioliti, Epidemiology, Immune debt, Pandemic, Risk factors, Settore MED/38 - Pediatria Generale e Specialistica

الوصف: Bronchiolitis is a common cause of hospitalization in infants. The long-lasting impact of hygiene and social behavior changes during the pandemic on this disease is debated. We investigated the prevalence of hospitalized cases, clinical severity, and underlying risk factors before and during pandemic. The study was conducted in 27 hospitals in Italy and included infants hospitalized for bronchiolitis during the following four periods: July 2018-March 2019, July 2020-March 2021, July 2021-March 2022, and July 2022-March 2023. Data on demographics, neonatal gestational age, breastfeeding history, underlying chronic diseases, presence of older siblings, etiologic agents, clinical course and outcome were collected. A total of 5330 patients were included in the study. Compared to 2018-19 (n = 1618), the number of hospitalizations decreased in 2020-21 (n = 121). A gradual increase was observed in 2021-22 (n = 1577) and 2022-23 (n = 2014). A higher disease severity (need and length of O2-supplementation, need for non-invasive ventilation, hospital stay) occurred in the 2021-22 and, especially, the 2022-23 periods compared to 2018-19. This tendency persisted after adjusting for risk factors associated with bronchiolitis severity. Conclusions:Compared to adults, COVID-19 in infants is often asymptomatic or mildly symptomatic and rarely results in hospitalization. This study indicates that the pandemic has indirectly induced an increased burdenof bronchiolitis among hospitalized infants. This shift, which is not explained by the recognized risk factors, suggests the existence of higher infant vulnerability during the last two seasons. What is known: • The pandemic led to a change in epidemiology of respiratory diseases •Large data on severity of bronchiolitis and underlying risk factors before and during COVID-19 pandemic are scarce What is new: •Compared to pre-pandemic period, hospitalizations for bronchiolitis decreased in 2020-21 and gradually increased in 2021-22 and 2022-23 •Compared to pre-pandemic period, higher ...

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/38236404; info:eu-repo/semantics/altIdentifier/wos/WOS:001144029100001; firstpage:1; lastpage:8; numberofpages:8; journal:EUROPEAN JOURNAL OF PEDIATRICS; https://hdl.handle.net/2434/1026466Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85182666566

الإتاحة: https://doi.org/10.1007/s00431-023-05395-1Test
https://hdl.handle.net/2434/1026466Test

المؤلفون: Lecce, Maurizio, Milani, Gregorio Paolo, Agostoni, Carlo, D'Auria, Enza, Banderali, Giuseppe, Biganzoli, Giacomo, Castellazzi, Luca, Paramithiotti, Costanza, Salvatici, Elisabetta, Tommasi, Paola, Zuccotti, Gian Vincenzo, Marchisio, Paola, Castaldi, Silvana

المساهمون: M. Lecce, G.P. Milani, C. Agostoni, E. D'Auria, G. Banderali, G. Biganzoli, L. Castellazzi, C. Paramithiotti, E. Salvatici, P. Tommasi, G.V. Zuccotti, P. Marchisio, S. Castaldi

مصطلحات موضوعية: SARS-CoV-2, adolescent, caregiver, children, infant, parent, vaccination, vaccine hesitancy, Settore MED/38 - Pediatria Generale e Specialistica, Settore MED/42 - Igiene Generale e Applicata

الوصف: The impact of Coronavirus disease 2019 (COVID-19) on the pediatric population is increasingly recognized. A widespread vaccination in childhood would provide benefits for children and might help ending the pandemic by enhancing community protection. Following recent approval by the European Medicines Agency (EMA) of Comirnaty (Pfizer-BioNTech) for children aged 5-11 years, we aimed to investigate caregivers' intention to vaccinate their children <12 years of age against COVID-19. A structured questionnaire was administered to caregivers of children aged <12 years visiting the Emergency Department or the outpatient clinics in three major hospitals of Milan, Italy, from 20 September to 17 October 2021. A total of 612 caregivers were invited to participate and 604 accepted (response rate >98%). Three questionnaires were excluded due to compiling errors and 601 were included in the analysis. A total of 311 (51.7%) caregivers stated they would have their child vaccinated, 138 (23%) would refuse to vaccinate their child and 152 (25.3%) were unsure. The intention to vaccinate the child was higher in caregivers vaccinated against COVID-19, in those with a bachelor's degree or higher level of education, and in those with friends/acquaintances who became ill or died due to COVID-19. This study shows that increasing efforts are necessary to provide evidence-based tailored information to caregivers and to promote vaccination in this pediatric age group.

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35712618; info:eu-repo/semantics/altIdentifier/wos/WOS:000811294300001; volume:10; firstpage:1; lastpage:9; numberofpages:9; journal:FRONTIERS IN PEDIATRICS; http://hdl.handle.net/2434/935712Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85132785385

الإتاحة: https://doi.org/10.3389/fped.2022.834363Test
http://hdl.handle.net/2434/935712Test

المؤلفون: Lecce, Maurizio, Milani, Gregorio Paolo, Agostoni, Carlo, D'Auria, Enza, Banderali, Giuseppe, Biganzoli, Giacomo, Castellazzi, Luca, Paramithiotti, Costanza, Salvatici, Elisabetta, Tommasi, Paola, Zuccotti, Gian Vincenzo, Marchisio, Paola, Castaldi, Silvana

المصدر: Frontiers in Pediatrics ; volume 10 ; ISSN 2296-2360

مصطلحات موضوعية: Pediatrics, Perinatology and Child Health

الوصف: The impact of Coronavirus disease 2019 (COVID-19) on the pediatric population is increasingly recognized. A widespread vaccination in childhood would provide benefits for children and might help ending the pandemic by enhancing community protection. Following recent approval by the European Medicines Agency (EMA) of Comirnaty (Pfizer-BioNTech) for children aged 5–11 years, we aimed to investigate caregivers' intention to vaccinate their children <12 years of age against COVID-19. A structured questionnaire was administered to caregivers of children aged <12 years visiting the Emergency Department or the outpatient clinics in three major hospitals of Milan, Italy, from 20 September to 17 October 2021. A total of 612 caregivers were invited to participate and 604 accepted (response rate >98%). Three questionnaires were excluded due to compiling errors and 601 were included in the analysis. A total of 311 (51.7%) caregivers stated they would have their child vaccinated, 138 (23%) would refuse to vaccinate their child and 152 (25.3%) were unsure. The intention to vaccinate the child was higher in caregivers vaccinated against COVID-19, in those with a bachelor's degree or higher level of education, and in those with friends/acquaintances who became ill or died due to COVID-19. This study shows that increasing efforts are necessary to provide evidence-based tailored information to caregivers and to promote vaccination in this pediatric age group.

الإتاحة: https://doi.org/10.3389/fped.2022.834363Test

المؤلفون: E. Salvatici, PARAMITHIOTTI, COSTANZA, S. Vincenti, M. Giovannini, V. Rovelli, R. Arancio

المساهمون: E. Salvatici, C. Paramithiotti, V. Rovelli, S. Vincenti, R. Arancio, M. Giovannini

مصطلحات موضوعية: Settore MED/38 - Pediatria Generale e Specialistica

العلاقة: journal:Shanti - ffrontiere; http://hdl.handle.net/2434/223447Test

الإتاحة: http://hdl.handle.net/2434/223447Test