المؤلفون: Jeong Eun Shin, Soon Min Lee, Mi-Jung Lee, Jungho Han, Joohee Lim, Haerin Jang, Ho Seon Eun, Min Soo Park, Soo Yeon Kim, Myung Hyun Sohn, Ji Ye Jung, Kyung Won Kim

المصدر: Clinical and Experimental Pediatrics, Vol 67, Iss 5, Pp 257-266 (2024)

مصطلحات موضوعية: prematurity, bronchopulmonary dysplasia, respiratory function test, cohort study, oligohydramnios, Pediatrics, RJ1-570

الوصف: Background The relationship between early life factors and childhood pulmonary function and structure in preterm infants remains unclear. Purpose This study investigated the impact of bronchopulmonary dysplasia (BPD) and perinatal factors on childhood pulmonary function and structure. Methods This longitudinal cohort study included preterm participants aged ≥5 years born between 2005 and 2015. The children were grouped by BPD severity according to National Institutes of Health criteria. Pulmonary function tests (PFTs) were performed using spirometry. Chest computed tomography (CT) scans were obtained and scored for hyperaeration or parenchymal lesions. PFT results and chest CT scores were analyzed with perinatal factors. Results A total 150 children (66 females) aged 7.7 years (6.4–9.9 years) were categorized into non/mild BPD (n=68), moderate BPD (n=39), and severe BPD (n=43) groups. The median z score for forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), FEV1/FVC ratio, and forced midexpiratory flow (FEF25%–75%) were significantly lower in the severe versus non/mild BPD group (-1.24 vs. -0.18, -0.22 vs. 0.41, -1.80 vs. -1.12, and -1.88 vs. -1.00, respectively; all P

وصف الملف: electronic resource

العلاقة: http://www.e-cep.org/upload/pdf/cep-2023-01053.pdfTest; https://doaj.org/toc/2713-4148Test

الوصول الحر: https://doaj.org/article/044ff35992e94cc6b024e9c258c11904Test

المؤلفون: Kadam, Digvijay^{1, 1}, Patil, Yamini¹, Patange, R. P.¹, Patil, Supriya¹, Sebastian, Shiju², Jarag, Ravindra³

المصدر: Research Journal of Pharmacy and Technology 17(2):746-750. 2024

المؤلفون: Sara Hanuna, Manca Velkavrh

المصدر: Slovenska pediatrija, Vol 31, Iss 1, Pp 31-36 (2024)

مصطلحات موضوعية: oligohydramnios, acute kidney injury, newborn, uteroplacental dysfunction, Medicine, Pediatrics, RJ1-570

الوصف: Amniotic fluid surrounds the fetus in uterus, protects him from outside injury, from infectious agents and has thermoregulating properties. Furthermore, it allows for its normal growth and development. The volume of amniotic fluid is a result of balance between fluid production and fluid movement out of the gestational sac. Oligohydramnios and anhydramnios are defined as decreased amniotic volume for gestational age or absent amniotic fluid, respectively. They can be associated with many maternal, fetal and placental causes, while some cases remain of unexplained etiology. Here, we present a case of a newborn, who presented with acute kidney injury due to uteroplacental dysfunction and oligohydramnios.

وصف الملف: electronic resource

العلاقة: http://www.slovenskapediatrija.si/Portals/0/Clanki/2024/Slovpediatr-2024-1-05en.pdfTest; https://doaj.org/toc/1318-4423Test; https://doaj.org/toc/2712-3960Test

الوصول الحر: https://doaj.org/article/2f1980267dc8485b9248ada719af8c31Test

المؤلفون: Matiyas Asrat Shiferaw, Ananya Solomon, Sintayehu Getachew, Wondimu Gudu

المصدر: BMC Women's Health, Vol 24, Iss 1, Pp 1-8 (2024)

مصطلحات موضوعية: Oligohydramnios, Outcome, Late term pregnancy, Post term pregnancy, Gynecology and obstetrics, RG1-991, Public aspects of medicine, RA1-1270

الوصف: Abstract Background The prevalence of oligohydramnios ranges from 12 to 14% after 41 weeks to as high as 30% in post term pregnancies. Oligohydramnios poses a dilemma in the choice of mode of labor and delivery in a setup where there is lack of continuous electronic fetal monitoring during labor. The condition also puts the mother at risks of operative interventions and cesarean delivery. We aimed to asses the maternal and perinatal outcomes in pregnancies with oligohydramnios in late term and post term pregnancy in this study. Methods A cross-sectional study was conducted among mothers with diagnosis of oligohydramnios after 40+ 6 weeks of gestation at four hospitals at four public hospitals in Addis Ababa, Ethiopia from May 1, 2021 to September 30, 2021. Data were collected using structured questionnaire. Logistic regression were performed to assess factors associated with the adverse maternal and perinatal outcomes. Results From a total of 142 mothers with oligohydramnios in late term and post tem pregnancies, 40.8% delivered through cesarean section. Spontaneous labor and elective cesarean section were more likely to occurr in parous women (AOR 2.5, 95% CI 1.06–6.04, p = 0.04), but with less likely in those with secondary level education (AOR 0.13, 95% CI 0.02–0.74, p = 0.02). There was no statistically significant difference in adverse outcomes between those who had induction of labor and those who had either spontaneous labor or had elective cesarean section. Conclusions The adverse maternal and perinatal outcomes in late term and post term pregnancies with oligohydramnios may not be different among different modes of delivery. Induction of labor can be safe in these particular group of women with intermittent auscultation with fetoscope in a setup where continuous electronic fetal monitoring is not readily available.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1472-6874Test

الوصول الحر: https://doaj.org/article/af133c2b93854800935ec523da40ed5dTest

المؤلفون: Martina Mandaletti, Elisa Cerchia, Elena Ruggiero, Elisabetta Teruzzi, Simona Bastonero, Annasilvia Pertusio, Marcello Della Corte, Andrea Sciarrone, Simona Gerocarni Nappo

المصدر: Frontiers in Pediatrics, Vol 12 (2024)

مصطلحات موضوعية: megacystis, megabladder, oligohydramnios, lower urinary tract obstruction, fetal, prenatal diagnosis, Pediatrics, RJ1-570

الوصف: IntroductionDiagnosis of prenatal megacystis has a significant impact on the pregnancy, as it can have severe adverse effects on fetal and neonatal survival and renal and pulmonary function. The study aims to investigate the natural history of fetal megacystis, to try to differentiate in utero congenital lower urinary tract obstruction (LUTO) from non-obstructive megacystis, and, possibly, to predict postnatal outcome.Materials and methodsA retrospective single-center observational study was conducted from July 2015 to November 2023. The inclusion criteria were a longitudinal bladder diameter (LBD) >7 mm in the first trimester or an overdistended/thickened-walled bladder failing to empty in the second and third trimesters. Close ultrasound follow-up, multidisciplinary prenatal counseling, and invasive and non-invasive genetic tests were offered. Informed consent for fetal autopsy was obtained in cases of termination of pregnancy or intrauterine fetal demise (IUFD). Following birth, neonates were followed up at the same center. Patients were stratified based on diagnosis: LUTO (G1), urogenital anomalies other than LUTO (“non-LUTO”) (G2), and normal urinary tract (G3).ResultsThis study included 27 fetuses, of whom 26 were males. Megacystis was diagnosed during the second and third trimesters in 92% of the fetuses. Of the 27 fetuses, 3 (11.1%) underwent an abortion, and 1 had IUFD. Twenty-three newborns were live births (85%) at a mean gestational age (GA) of 34 ± 2 weeks. Two patients (neonates) died postnatally due to severe associated malformations. Several prenatal parameters were evaluated to differentiate patients with LUTO from those with non-LUTO, including the severity of upper tract dilatation, keyhole sign, oligohydramnios, LBD, and GA at diagnosis. However, none proved predictive of the postnatal diagnosis. Similarly, none of the prenatal parameters evaluated were predictive of postnatal renal function.DiscussionThe diagnosis of megacystis in the second and third trimesters was associated with live births in up to 85% of cases, with LUTO identified as the main cause of fetal megacystis. This potentially more favorable outcome, compared to the majority reported in literature, should be taken into account in prenatal counseling. Megacystis is an often misinterpreted antennal sign that may hide a wide range of diagnoses with different prognoses, beyond an increased risk of adverse renal and respiratory outcomes.

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fped.2024.1379267/fullTest; https://doaj.org/toc/2296-2360Test

الوصول الحر: https://doaj.org/article/896285f7329f490d9f90c020b550b02eTest

المؤلفون: Deepak Jain, Rajesh Kumar Singh, Jyoti Jaiswal, Pranjali Mittal, Satyabhuwan Singh Netam

المصدر: iRADIOLOGY, Vol 1, Iss 4, Pp 285-293 (2023)

مصطلحات موضوعية: oligohydramnios, polyhydramnios, pulsality index, resistive index, Medical physics. Medical radiology. Nuclear medicine, R895-920

الوصف: Abstract Objective To compare the renal artery (RA) flow indices (RI and PI) among normohydramnios, idiopathic oligohydramnios, and polyhydramnios and determine applicability of fetal RA Doppler indices in predicting the pregnancy outcome. Methods Total 106 3rd trimester pregnant patients were divided into cases and controls based on amniotic fluid index. Routine antenatal and color Doppler (including kidneys) ultrasound was performed for all patients in this study. The postnatal follow‐up was done, and the pregnancies having poor outcomes in terms of NICU admissions were assessed. Results Statistically significant differences were noted when comparing RI and PI values of normohydramnios (0.91 ± 0.04 and 2.38 ± 0.21, respectively) with oligohydramnios (1.02 ± 0.07 and 2.99 ± 0.38, respectively) and polyhydramnios (0.90 ± 0.12 and 2.7 ± 0.84, respectively) independently (p value

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2834-2860Test; https://doaj.org/toc/2834-2879Test

الوصول الحر: https://doaj.org/article/5541c1e30c574627a57dc284c19cfad6Test

المؤلفون: Rathika Damodara Shenoy, Seema Pavaman Sindgikar, Praveen Nayak K., Raghuraj Uppoor, Shalini Singh

المصدر: Journal of Pediatric and Neonatal Individualized Medicine, Vol 13, Iss 1, Pp e130118-e130118 (2024)

مصطلحات موضوعية: bidi rolling, occupational tobacco handling, doppler, fetal growth restriction, nicotine, oligohydramnios, Medicine, Pediatrics, RJ1-570

الوصف: Introduction: Tobacco exposure during pregnancy has a negative influence on fetal growth. Maternal smoking causes placental vaso­constriction and fetal growth restriction (FGR). In India, the tobacco industry employs women to hand roll cigarettes called bidis. A bidi roller handles 120 g of tobacco and therefore 3 g of nicotine per day. Aim: To evaluate the effect of occupational tobacco handling by pregnant women on fetal growth and wellbeing. Methods: In this cohort study, 177 pregnant bidi rollers (exposed cohort) and 354 pregnant non-rollers (unexposed cohort) were followed up from 18-22 weeks of pregnancy until delivery with fetal sonogram and Doppler. Fetal surveillance data (including fetal biometry, Doppler indices, amniotic fluid index, biophysical profile and placentation) were recorded and compared. Maternal nicotine absorption was quantified by serum cotinine. Intergroup differences and relative risk (RR) were determined by Chi-square test (or Fisher exact when the count was ≤ 5), and adjusted odds ratio (OR) by binary logistic regression. Intrauterine growth trend was plotted. Results: Fetal surveillance results were ab­normal in 37.9% of the tobacco-exposed group, with a RR of 1.6 (p = 0.001) and adjusted OR of 1.8 (p = 0.005) in comparison with the unex­posed group. Nicotine absorption was evident in 28.4% of the bidi rollers that had abnormal fetal surveillance results. The mean estimated fetal weight and head circumference demonstrated a sustained deceleration, starting at 28-30 weeks of gestation, in the exposed group. Doppler data suggested fetal adaptation to maintain cerebral circulation. We found a higher frequency of oligohydramnios (statistically significant), pla­cental abruption (not statistically significant), and placenta previa (not statistically significant) in the tobacco-exposed group. Conclusions: Occupational tobacco handling in bidi rollers resulted in early-onset symmetric FGR and compromised wellbeing. Pregnant women with any form of tobacco exposure require vigilant fetal surveillance.

وصف الملف: electronic resource

العلاقة: https://jpnim.com/index.php/jpnim/article/view/1618Test; https://doaj.org/toc/2281-0692Test

الوصول الحر: https://doaj.org/article/b6f5b06c37ce486da375924307733675Test

المؤلفون: Besfat Berihun Erega, Wassie Yazie Ferede, Fillorenes Ayalew Sisay, Abeba Belay Ayalew, Rahel Birhanu Arage

المصدر: Physiological Reports, Vol 12, Iss 6, Pp n/a-n/a (2024)

مصطلحات موضوعية: amniotic fluid, Ethiopia, maternal condition, oligohydramnios, polyhydramnios, Physiology, QP1-981

الوصف: Abstract The amniotic fluid is a protective liquid found in amniotic found in the amniotic sac and mainly containing water and some solid substances including epitheloid and fibroblastic type cells. Most of the studies conducted about amniotic fluid volume (AFV) reported fetal and placental factors as a determinant of AFV. The aim of this study is to examine maternal and obstetric conditions in relation to AFV among women with term pregnancies. A multicenter institutional based cross‐sectional study was conducted among clients attending selected public hospitals of South Gondar Zone, Ethiopia from January 01, 2023 to May 30, 2023. The sample size was calculated by using the assumption of single population proportion formula considering the prevalence value of 50%, 95% confidence interval, and margin of error 5% and 10% non respondent rate. In our study rural residency AOR = 3.21 (1.19–5.37), chronic illness AOR = 2.12 (1.33–4.61), short inter pregnancy interval AOR = 3.03 (2.18–6.28), Hypermesis gravidarum AOR = 1.19 (1.02–4.41), and maternal diabetics AOR = 2.16 (1.32–4.75) had significant association with the outcome variable. These maternal conditions may be correlated with an abnormal volume of amniotic fluid.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2051-817XTest

الوصول الحر: https://doaj.org/article/6755fb79f4664447abadd3bfe9861e05Test

المؤلفون: Madhuri, Narra, Pal, Chayan Kumar, Sharma, Parthapratim

المصدر: International Journal of Reproduction, Contraception, Obstetrics and Gynecology; Vol. 13 No. 6 (2024): June 2024; 1548-1553 ; 2320-1789 ; 2320-1770

مصطلحات موضوعية: Polyhydramnios, Amniotic fluid index, Oligohydramnios, NICU admission, Caesarean section

الوصف: Background: Variation in the amniotic fluid reflects fetal compromise, and congenital anomalies and also may predict perinatal morbidity and mortality. Methods: Singleton pregnancy subjects with well-established dates at ≥28 weeks of gestational age were taken into study. These subjects were ultrasonographically diagnosed to have abnormal liquor volumes. This study was a hospital-based single-center prospective observational study conducted in Midnapore medical college and hospital, west Bengal. The chi-square test was applied for statistical significance and a p<0.05 was considered to be significant. Results: In all subjects of abnormal liquor volume, the incidence of oligohydramnios and polyhydramnios are in the proportion of 3:1 in our study. Postdated pregnancy (28.4%), hypertensive disease (16.8%), intrauterine growth restriction (IUGR) (12.6%), and anemia (2.2%) were associated with oligohydramnios. Congenital anomalies (23.3%), GDM (16.6%), and Rh-incompatibility (3.3%) were associated with polyhydramnios. The incidence of caesarean section, meconium-stained liquor and 5-minute APGAR score <7 and NICU admission was higher in the oligohydramnios group as compared to polyhydramnios. In abnormal liquor volume, the statistical association was significant with onset of labour (p=0.00), mode of delivery (p=0.00), the colour of liquor(p-0.00), and fetal outcome (p=0.00). Conclusions: Postdated pregnancy, IUGR, and hypertensive disorders were associated with oligohydramnios and congenital anomalies, and GDM and Rh-isoimmunization were associated with polyhydramnios. In abnormal liquor volume onset of labour, mode of delivery, the colour of the liquor, and fetal outcome were significant.

وصف الملف: application/pdf

العلاقة: https://www.ijrcog.org/index.php/ijrcog/article/view/14140/8793Test; https://www.ijrcog.org/index.php/ijrcog/article/view/14140Test

الإتاحة: https://doi.org/10.18203/2320-1770.ijrcog20241442Test
https://www.ijrcog.org/index.php/ijrcog/article/view/14140Test

المؤلفون: Abhilasha Jain, Arvind Meena, Yogesh Gupta, Chandrashekhar Waghmare

مصطلحات موضوعية: Perinatal, Maternal, Outcome, Oligohydramnios

الوصف: Introduction: Nature has made floating bed in the form of amniotic fluid cavity filled with liquor amnii for the requirement of fetus, for its existence and growth in sterile environment. Levels of amniotic fluids affects 2.4% of pregnancies. Early onset oligohydramnios has been associated with fetal congenital anomalies and poor fetal outcome. Hence this study was designed to observe effects of oligohydramnios in perinatal and post-natal phases and their outcomes Methodology: The present study was carried out in the department of obstetrics and gynecology at tertiary care institute of Madhya Pradesh over a period of one. In this hospital-based study a total of 227 patients of gestational age >37 weeks and ≤40 weeks were involved with 27 drop-outs. Hence finally 200 patients were selected for this study of which 100 had an AFI ≤5 and were included in the study group and 100 had an AFI>5. Results: Results of present studies shows Birth weight in Group1 out of 100 cases whom AFI >5cm; 24(24%) babies ... : Introduction: Nature has made floating bed in the form of amniotic fluid cavity filled with liquor amnii for the requirement of fetus, for its existence and growth in sterile environment. Levels of amniotic fluids affects 2.4% of pregnancies. Early onset oligohydramnios has been associated with fetal congenital anomalies and poor fetal outcome. Hence this study was designed to observe effects of oligohydramnios in perinatal and post-natal phases and their outcomes Methodology: The present study was carried out in the department of obstetrics and gynecology at tertiary care institute of Madhya Pradesh over a period of one. In this hospital-based study a total of 227 patients of gestational age >37 weeks and ≤40 weeks were involved with 27 drop-outs. Hence finally 200 patients were selected for this study of which 100 had an AFI ≤5 and were included in the study group and 100 had an AFI>5. Results: Results of present studies shows Birth weight in Group1 out of 100 cases whom AFI >5cm; 24(24%) babies ...

العلاقة: https://dx.doi.org/10.5281/zenodo.11094787Test

الإتاحة: https://doi.org/10.5281/zenodo.1109478610.5281/zenodo.11094787Test