المؤلفون: Sharma, R, Abbasi-Kangevari, M, Abd-Rabu, R, Abidi, H, Abu-Gharbieh, E, Acuna, JM, Adhikari, S, Advani, SM, Afzal, MS, Meybodi, MA, Ahinkorah, BO, Ahmad, S, Ahmadi, A, Ahmadi, S, Ahmed, H, Ahmed, LA, Ahmed, MB, Al Hamad, H, Alahdab, F, Alanezi, FM, Alanzi, TM, Alhalaiqa, FAN, Alimohamadi, Y, Alipour, V, Aljunid, SM, Alkhayyat, M, Almustanyir, S, Al-Raddadi, RM, Alvand, S, Alvis-Guzman, N, Amini, S, Ancuceanu, R, Anoushiravani, A, Anoushirvani, AA, Ansari-Moghaddam, A, Arabloo, J, Aryannejad, A, Jafarabadi, MA, Athari, SS, Ausloos, F, Ausloos, M, Awedew, AF, Awoke, MA, Ayana, TM, Azadnajafabad, S, Azami, H, Azangou-Khyavy, M, Jafari, AA, Badiye, AD, Bagherieh, S, Bahadory, S, Baig, AA, Baker, JL, Banach, M, Barrow, A, Berhie, AY, Besharat, S, Bhagat, DS, Bhagavathula, AS, Bhala, N, Bhattacharyya, K, Bhojaraja, VS, Bibi, S, Bijani, A, Biondi, A, Bjorge, T, Bodicha, BBA, Braithwaite, D, Brenner, H, Calina, D, Cao, C, Cao, Y, Carreras, G, Carvalho, F, Cerin, E, Chakinala, RC, Cho, WCS, Chu, DT, Conde, J, Costa, VM, Cruz-Martins, N, Dadras, O, Dai, XC, Dandona, L, Dandona, R, Danielewicz, A, Demeke, FM, Demissie, GD, Desai, R, Dhamnetiya, D, Dianatinasab, M, Diaz, D, Didehdar, M, Doaei, S, Doan, LP, Dodangeh, M, Eghbalian, F, Ejeta, DD, Ekholuenetale, M, Ekundayo, TC, El Sayed, I, Elhadi, M, Enyew, DB, Eyayu, T, Ezzeddini, R, Fakhradiyev, IR, Farooque, U, Farrokhpour, H, Farzadfar, F, Fatehizadeh, A, Fattahi, H, Fattahi, N, Fereidoonnezhad, M, Fernandes, E, Fetensa, G, Filip, I, Fischer, F, Foroutan, M, Gaal, PA, Gad, MM, Gallus, S, Garg, T, Getachew, T, Ghamari, SH, Ghashghaee, A, Ghith, N, Gholamalizadeh, M, Navashenaq, JG, Gizaw, AT, Glasbey, JC, Golechha, M, Goleij, P, Gonfa, KB, Gorini, G, Guha, A, Gupta, S, Gupta, VB, Gupta, VK, Haddadi, R, Hafezi-Nejad, N, Haj-Mirzaian, A, Halwani, R, Haque, S, Hariri, S, Hasaballah, A, Hassanipour, S, Hay, S, Herteliu, C, Holla, R, Hosseini, MS, Hosseinzadeh, M, Hostiuc, M, Househ, M, Huang, J, Humayun, A, Iavicoli, I, Ilesanmi, OS, Ilic, IM, Ilic, MD, Islami, F, Iwagami, M, Jahani, MA, Jakovljevic, M, Javaheri, T, Jayawardena, R, Jebai, R, Jha, RP, Joo, T, Joseph, N, Joukar, F, Jozwiak, JJ, Kabir, A, Kalhor, R, Kamath, A, Kapoor, N, Karaye, IM, Karimi, A, Kauppila, JH, Kazemi, A, Keykhaei, M, Khader, YS, Khajuria, H, Khalilov, R, Khanali, J, Khayamzadeh, M, Khodadost, M, Kim, H, Kim, MS, Kisa, A, Kisa, S, Kolahi, AA, Koohestani, HR, Kopec, JA, Koteeswaran, R, Koyanagi, A, Krishnamoorthy, Y, Kumar, GA, Kumar, M, Kumar, V, La Vecchia, C, Lami, FH, Landires, I, Ledda, C, Lee, SW, Lee, WC, Lee, YY, Leong, E, Li, B, Lim, SS, Lobo, SW, Loureiro, JA, Lunevicius, R, Madadizadeh, F, Mahmoodpoor, A, Majeed, A, Malekpour, MR, Malekzadeh, R, Malik, AA, Mansour-Ghanaei, F, Mantovani, LG, Martorell, M, Masoudi, S, Mathur, P, Meena, JK, Nasab, EM, Mendoza, W, Mentis, AFA, Mestrovic, T, Jonasson, JM, Miazgowski, B, Miazgowski, T, Mijena, GFW, Mirmoeeni, S, Mirza-Aghazadeh-Attari, M, Mirzaei, H, Misra, S, Mohammad, KA, Mohammadi, E, Mohammadi, S, Mohammadi, SM, Mohammadian-Hafshejani, A, Mohammed, S, Mohammed, TA, Moka, N, Mokdad, AH, Mokhtari, Z, Molokhia, M, Momtazmanesh, S, Monasta, L, Moradi, G, Moradzadeh, R, Moraga, P, Morgado-da-Costa, J, Mubarik, S, Mulita, F, Naghavi, M, Naimzada, MD, Nam, HS, Natto, ZS, Nayak, BP, Nazari, J, Nazemalhosseini-Mojarad, E, Negoi, I, Nguyen, CT, Nguyen, SH, Noor, NM, Noori, M, Noori, SMA, Nunez-Samudio, V, Nzoputam, CI, Oancea, B, Odukoya, OO, Oguntade, AS, Okati-Aliabad, H, Olagunju, AT, Olagunju, TO, Ong, S, Ostroff, SM, Padron-Monedero, A, Pakzad, R, Pana, A, Pandey, A, Kan, FP, Patel, UK, Paudel, U, Pereira, RB, Perumalsamy, N, Pestell, RG, Piracha, ZZ, Pollok, RCG, Pourshams, A, Pourtaheri, N, Prashant, A, Rabiee, M, Rabiee, N, Radfar, A, Rafiei, S, Rahman, M, Rahmani, AM, Rahmanian, V, Rajai, N, Rajesh, A, Ramezani-Doroh, V, Ramezanzadeh, K, Ranabhat, K, Rashedi, S, Rashidi, A, Rashidi, MM, Rastegar, M, Rawaf, DL, Rawaf, S, Rawassizadeh, R, Razeghinia, MS, Renzaho, AMN, Rezaei, N, Rezaei, S, Rezaeian, M, Rezazadeh-Khadem, S, Roshandel, G, Saber-Ayad, MM, Saberzadeh-Ardestani, B, Saddik, B, Sadeghi, H, Saeed, U, Sahebazzamani, M, Sahebkar, A, Farrokhi, AS, Salimi, A, Salimzadeh, H, Samadi, P, Samaei, M, Samy, AM, Sanabria, J, Santric-Milicevic, MM, Saqib, MAN, Sarveazad, A, Sathian, B, Satpathy, M, Schneider, IJC, Sekerija, M, Sepanlou, SG, Seylani, A, Sha, F, Shafiee, SM, Shaghaghi, Z, Shahabi, S, Shaker, E, Sharifian, M, Sharifi-Rad, J, Sheikhbahaei, S, Shetty, JK, Shirkoohi, R, Shobeiri, P, Malleshappa, SKS, Silva, DAS, Julian, GS, Singh, AD, Singh, JA, Siraj, MS, Sivandzadeh, GR, Skryabin, VY, Skryabina, AA, Socea, B, Solmi, M, Soltani-Zangbar, MS, Song, SH, Szerencses, V, Szocska, M, Tabares-Seisdedos, R, Tabibian, E, Taheri, M, Abkenar, YT, Taherkhani, A, Talaat, IM, Tan, KK, Tbakhi, A, Tesfaye, B, Tiyuri, A, Tollosa, DN, Touvier, M, Tran, BX, Tusa, BS, Ullah, I, Ullah, S, Vacante, M, Tahbaz, SV, Veroux, M, Vo, B, Vos, T, Wang, C, Westerman, R, Woldemariam, M, Jabbari, SHY, Yang, L, Yazdanpanah, F, Yu, CH, Yuce, D, Yunusa, I, Zadnik, V, Zahir, M, Zare, I, Zhang, ZJ, Zoladi, M

المصدر: The lancet. Gastroenterology & hepatology. 7(7):627-647

مصطلحات موضوعية: Medicin och hälsovetenskap

الوصول الحر: http://kipublications.ki.se/Default.aspx?queryparsed=id:150889893Test

المؤلفون: Nazemalhosseini-Mojarad, E., Sanjabi, F., Babini, H.

مصطلحات موضوعية: WK Endocrine System, WI Digestive System, QZ Pathology

العلاقة: Nazemalhosseini-Mojarad, E. and Sanjabi, F. and Babini, H. (2020) The role of epithelial-mesenchymal transition markers in the prediction of lymph node metastases in colorectal cancer. Biomarkers in Medicine, 14 (6). pp. 417-420.

الإتاحة: http://eprints.iums.ac.ir/23818Test/

المؤلفون: Pezeshkian Z., Nobili S., Peyravian N., Shojaee B., Nazari H., Soleimani H., Asadzadeh-Aghdaei H., Bonab M. A., Nazemalhosseini-Mojarad E., Mini E.

المساهمون: Pezeshkian, Z., Nobili, S., Peyravian, N., Shojaee, B., Nazari, H., Soleimani, H., Asadzadeh-Aghdaei, H., Bonab, M. A., Nazemalhosseini-Mojarad, E., Mini, E.

مصطلحات موضوعية: Colorectal cancer, Matrix Metalloproteinases (MMPs), MMP polymorphism, MMP targeting, Polyp, TIMPs

الوصف: Colorectal cancer (CRC) is the third and second cancer for incidence and mortality worldwide, respectively, and is becoming prevalent in developing countries. Most CRCs derive from polyps, especially adenomatous polyps, which can gradually transform into CRC. The family of Matrix Metalloproteinases (MMPs) plays a critical role in the initiation and progression of CRC. Prominent MMPs, including MMP-1, MMP-2, MMP-7, MMP-8, MMP-9, MMP-12, MMP-13, MMP-14, and MMP-21, have been detected in CRC patients, and the expression of most of them correlates with a poor prognosis. Moreover, many studies have explored the inhibition of MMPs and targeted therapy for CRC, but there is not enough information about the role of MMPs in polyp malignancy. In this review, we discuss the role of MMPs in colorectal cancer and its pathogenesis.

وصف الملف: STAMPA

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34944846; info:eu-repo/semantics/altIdentifier/wos/WOS:000736067400001; volume:13; issue:24; firstpage:Art. N° 6226; numberofpages:20; journal:CANCERS; http://hdl.handle.net/11564/767433Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85120825953

الإتاحة: https://doi.org/10.3390/cancers13246226Test
http://hdl.handle.net/11564/767433Test

المؤلفون: Asadzadeh Aghdaei H, Ahmadi Bashirzadeh D, Nazemalhosseini Mojarad E, Rezasoltani S, Shabnam Shahrokh, Mohsen Norouzinia

المصدر: Middle East Journal of Digestive Diseases

مصطلحات موضوعية: 0301 basic medicine, Microbial diversity, Computational biology, Review Article, Gut microbiota, Gut flora, digestive system, 03 medical and health sciences, Taxonomic composition, Human health, 0302 clinical medicine, Microbiome analysis techniques, Medicine, Microbiome, Hepatology, biology, business.industry, digestive, oral, and skin physiology, Gastroenterology, biology.organism_classification, Disadvantages, Gut microbiome, 030104 developmental biology, Metagenomics, 030220 oncology & carcinogenesis, Amplicon sequencing, Advantages, business

الوصف: Gut microbiota is considered as a human organ with its own specific functions and complexity. Development of novel techniques such as shut gun sequencing, metagenomics, and next-generation sequencing (NGS) has enabled bypassing the traditional culturedependent bias and has significantly expanded our understanding of the composition, diversity, and roles of the gut microbiota in human health and diseases. Although amplicon sequencing characterizes the taxonomic composition of the gut microbiome, it is impossible to cover the direct evidence of the microbial biological functions related to the gut microbial community. Hence, the critical next step for gut microbiome studies is shifting from gene/ genome-centric analysis to mechanism-centric techniques by integrating omics data with experimental results. Realizing gut microbial diversity and their bioactive metabolites function will provide insight into the clinical application of gut microbiota in diagnoses and treatments of several diseases. In this review, we focused on explaining the conventional and advanced microbiome analysis techniques regarding gut microbiota investigation with considering the advantages and disadvantages of the platforms.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13757ae971fcabf3a2878a2e2df60841Test
http://europepmc.org/articles/PMC7023644Test

المؤلفون: Tajeddin, E. (MSc), Jahani Sherafat, S. (MSc), Seyyed Majidi, M. R. (MD), Alebouyeh, M. (PhD), Nazemalhosseini mojarad, E. (MSc), Pourhossengholi, A. (PhD), Mohammad Alizadeh A H (MD), Zali, MR (MD)

المصدر: Medical Laboratory Journal, Vol 5, Iss 2, Pp 34-43 (2011)

مصطلحات موضوعية: bile stones, bacteria, ercp, antibiotics., Medicine

الوصف: Abstract Background and objectives: Bile in healthy people is a sterile fluid and presence of any microorganism can be a marker for a disorder like cholelithiasis. The aim of this study was to determine the frequency of bacterial agents in the bile of patients with bilestone, malignant pancreatic and biliary diseases. Material and Methods: One hundred and two bile samples were obtained, during six months in 2011, from patients subjected to ERCP in Taleghani hospital, Tehran. First, Patientchr('39')s clinical data, the type stone, and their disease status were studied, and then the microbiological investigations, such as culture, identification of the bacteria and detection of their counts, drug susceptibility testing and molecular tests (16s rDNA PCR) performed on all the samples. Higher than 103 bacteria counts for each sample, in the absence of underlying infections, was considered as stable colonization. We run SPSS version 13 to analyze the data. Results: Out of 42(41.1%) positive bile culture samples, 59 bacterial isolates are detected by conventional methods. Of culture negative samples, seven have bacterial DNA indicated by PCR method. The most isolated bacteria are E. coli (%34.4), Enterococcus spp. (%19.7), Klebsiella pneumoniae (%18) and Pseudomonas aeruginos (18%). The most frequent stones are cholesterol, black pigment and brown pigment, respectively. There is no significant association between the diseases, stones and types of bacteria. Previous antibiotic usage (44.6%) is meaningfully more than that of other biliary problems (p=0.01) Conclusion: The presence of bacteria, Escherchi coli and Entrococcus which are the most in bile samples, is considered as a risk factor in pathogenesis of biliary disorders. Further studies on the pathogenesis and pathophysiological effects of bacteria can help us to clarify the role of bacteria in producing bile stones. Key words: Bile stones, Bacteria, ERCP, Antibiotics.

وصف الملف: electronic resource

العلاقة: http://mlj.goums.ac.ir/article-1-169-en.htmlTest; https://doaj.org/toc/2538-4449Test

الوصول الحر: https://doaj.org/article/da32ca4aa129419d9ab7edccf4c98bc3Test

المؤلفون: Rostami Nejad M (BS), Nazemalhosseini Mojarad E (MSc), Taghipour N (MSc), Nochi Z (MSc), Cheraghipour K (MSc), Dabiri H (PhD), Mohebbi SR (PhD), Noorinayer B (MD), Zali MR (MD)

المصدر: مجله دانشگاه علوم پزشکی گرگان, Vol 13, Iss 2, Pp 61-67 (2011)

مصطلحات موضوعية: Echinococcus granulosus, atp6 gene, G1 genotypes, G6 genotypes, Medicine, Medicine (General), R5-920

الوصف: Background and Objective: Several strains of the Echinococcus granulosus have been described based on morphological characters, intermediate host specificity and/or genetic analysis of mitochondrial and nuclear DNA. The aim of this study was to characterize different E.granulosus isolates by using sequences of mitochondrial atp6 gene. Materials and Methods: In this study, Sixty infected liver and lungs of cattle, sheep and goats were collected from the abattoir of Varamin city-Iran during 2008. Protoscoleces were removed from each fertile cyst and DNA extracted. New and specific primers were designed for two existing genotypes (G1 and G6) of E. granulosus known to occur in Iran and applied in PCR reactions. Results: The new primers selectively amplified the G1 and G6 genotypes of E. granulosus with specific bands of 708 and 705 bp respectively. The G1 genotype was identified in all fertile cyst samples. Conclusion: This study showed that the new primer pairs which specifically amplify portions of the mitochondrial atp6 gene of the G1 and G6 strains of Echinococcus granulosus are proper molecular marker for investigating genetic variation in a number of isolates of E. granulosus from a range of hosts (sheep, goats, cattle) in Iran. The result of sequenced samples showed that our sequences were the same as those reported previously for these strains.

وصف الملف: electronic resource

العلاقة: http://goums.ac.ir/journal/browse.php?a_code=A-10-1-513&slc_lang=en&sid=1Test; https://doaj.org/toc/1562-4765Test; https://doaj.org/toc/2008-4080Test

الوصول الحر: https://doaj.org/article/3eddf23d77764f94a01a8b294c064b5aTest

المؤلفون: Derakhshani, S., Baradaran Ghavami, S., Damavand, B., Azimzadeh, P., Mohebbi, S.R., Nazemalhosseini Mojarad, E., Asadzadeh Aghdaieb, H.

المصدر: Annals of Oncology ; volume 25, page iv223 ; ISSN 0923-7534

مصطلحات موضوعية: Oncology, Hematology

الإتاحة: https://doi.org/10.1093/annonc/mdu334.39Test
https://api.elsevier.com/content/article/PII:S0923753419521044?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0923753419521044?httpAccept=text/plainTest
http://academic.oup.com/annonc/article-pdf/25/suppl_4/iv223/9690465/mdu334.39.pdfTest

المؤلفون: Nazemalhosseini-Mojarad, E., Asadzadeh-Aghdaei, H., Mohammadpour, S., Esfahani, A.T., Porhoseingholi, M.A., Molaei, M., Jalali, A., Kuppen, P.J.K., Zali, M.R.

المصدر: Journal of Cancer Research and Therapeutics

مصطلحات موضوعية: Clinicopathological characteristics, colorectal neoplasms, human leukocyte antigen, microsatellite instability, survival analysis

الوصف: Aim: In the present study, we evaluated the clinical prognostic value of human leukocyte antigen (HLA (Class I tumor cell expression in a series of colorectal cancer (CRC) patients and also explored the association of this expression profile with molecular features such as mutation status of KRAS and BRAF, microsatellite stability status, and clinicopathological characteristics of the patients. Patients and Methods: Formalin-fixed paraffin-embedded tumor tissue of 258 CRC patient's sections were immunohistochemically stained and subsequently quantified for HLA Class I expression by the tumor cells. Determination of microsatellite instability (MSI) tumor status was ascertained using mononucleotide repeat microsatellite targets. KRAS and BRAF mutations were screened by polymerase chain reaction (PCR)-sequencing and cast-PCR, respectively. Results: HLA Class I expression was normal in 91 cases (35.3%), downregulated in 119 (46.1%), and loss of expression in 48 (18.6%) cases. Forty (15.5%) tumors were MSI-H (MSH), 49 were MSI-L (19%), and 169 were microsatellite stable (MSS) (65.5%). Thirty-six (14%) and 15 (5.8%) of the patients exhibited mutation in the KRAS and BRAF, respectively. It was found that patients with downregulated expression of HLA Class I were associated with Stage II tumors (P < 0.001) and a MSS tumor status (P < 0.001), while patients with loss of expression were associated with MSH status (P < 0.001). Univariate and multivariate analyses revealed that HLA Class I downregulated expression was an independent prognostic parameter for shorter overall patient survival time (hazard ratio: 1.8, P = 0.003). Conclusions:HLA Class I expression is an independent and sensitive clinical prognostic marker that might be used in CRC patients. ; Surgical oncology

وصف الملف: application/pdf

العلاقة: https://www.cancerjournal.net/article.asp?issn=0973-1482;year=2020;volume=16;issue=8;spage=165;epage=171;aulastTest=Nazemalhosseini%2DMojarad; lumc-id: 115482846; https://hdl.handle.net/1887/3185312Test

الإتاحة: https://doi.org/10.4103/jcrt.JCRT_429_18Test
https://hdl.handle.net/1887/3185312Test
https://www.cancerjournal.net/article.asp?issn=0973-1482;year=2020;volume=16;issue=8;spage=165;epage=171;aulastTest=Nazemalhosseini%2DMojarad

المؤلفون: Rostami-Nejad, M., Rostami, K, Sanaei, M., Mohebbi, S.R., Al-Dulaimi, D., Nazemalhosseini-Mojarad, E., Collin, P., Mulder, C.J.J., Zali, M.R.

المصدر: Rostami-Nejad , M , Rostami , K , Sanaei , M , Mohebbi , S R , Al-Dulaimi , D , Nazemalhosseini-Mojarad , E , Collin , P , Mulder , C J J & Zali , M R 2010 , ' Rotavirus and coeliac autoimmunity among adults with non-specific gastrointestinal symptoms ' , Saudi Medical Journal , vol. 30 , no. 8 , pp. 891-894 .

وصف الملف: application/pdf

العلاقة: https://research.vumc.nl/en/publications/e5f21c0b-f10a-4c36-93b6-dcaaf982372fTest

الإتاحة: https://research.vumc.nl/en/publications/e5f21c0b-f10a-4c36-93b6-dcaaf982372fTest
https://research.vumc.nl/ws/files/704459/257275.pdfTest

المؤلفون: Nazemalhosseini Mojarad E, Zali Mr

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/25/0d/Iran_J_Microbiol_2011_Sep_3(3)_156-158.tar.gz

الوصف: An immunosuppressed man was admitted to hospital with diarrhea and a history of urinary tract infection. He was subjected to treatment with antibiotics. The patient died of putative severe sepsis. The etiological agent was a carbapenemase producing isolate of Bacillus circulans with resistance to all prescribed antimicrobial agents.

وصف الملف: application/zip

العلاقة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.271.8285Test