المؤلفون: Fonseca, NM, Maurice-Dror, C, Herberts, C, Tu, W, Fan, W, Murtha, AJ, Kollmannsberger, C, Kwan, EM, Parekh, K, Schonlau, E, Bernales, CQ, Donnellan, G, Ng, SWS, Sumiyoshi, T, Vergidis, J, Noonan, K, Finch, DL, Zulfiqar, M, Miller, S, Parimi, S, Lavoie, JM, Hardy, E, Soleimani, M, Nappi, L, Eigl, BJ, Taavitsainen, S, Nykter, M, Tolmeijer, SH, Boerrigter, E, Mehra, N, van Erp, NP, De Laere, B, Lindberg, J, Gronberg, H, Khalaf, DJ, Annala, M, Chi, KN, Wyatt, AW

المصدر: Nature communications. 15(1):1828

مصطلحات موضوعية: Medicin och hälsovetenskap

الوصول الحر: http://kipublications.ki.se/Default.aspx?queryparsed=id:155474166Test

المؤلفون: Murgano, D, Khalil, A, Prefumo, F, Van Mieghem, T, Rizzo, G, Heyborne, KD, Melchiorre, K, Peeters, S, Lewi, L, Familiari, A, Lopriore, E, Oepkes, D, Murata, M, Anselem, O, Buca, D, Liberati, M, Hack, K, Nappi, L, Baxi, LV, Scambia, G, Acharya, G, D'Antonio, F

المصدر: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. 55(3):310-317

مصطلحات موضوعية: Medicin och hälsovetenskap

الوصول الحر: http://kipublications.ki.se/Default.aspx?queryparsed=id:143055727Test

المؤلفون: Voltas, N., Hernández-Martínez, C., Cibelli, G., Nappi, L., Valenzano, A., Arija, V.

المصدر: Psicosomàtica y Psiquiatría; Núm. 5 (2018)
Psicosomàtica y Psiquiatría; Núm. 5 (2018): abril-mayo-junio

مصطلحات موضوعية: Último trimestre de embarazo, Postparto, Estados emocionales, Comparación

وصف الملف: application/pdf

العلاقة: http://www.raco.cat/index.php/PsicosomPsiquiatr/article/view/393325/486791Test

الوصول الحر: http://www.raco.cat/index.php/PsicosomPsiquiatr/article/view/393325Test

المؤلفون: Nappi, L., Mazurek, S., Khazamipour, N., Janfaza, S., Jia, A., Ozcan, G., Ozgun, G.

المصدر: ESMO Open ; volume 9, page 102352 ; ISSN 2059-7029

مصطلحات موضوعية: Cancer Research, Oncology

الإتاحة: https://doi.org/10.1016/j.esmoop.2024.102352Test
https://api.elsevier.com/content/article/PII:S2059702924001200?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2059702924001200?httpAccept=text/plainTest

المؤلفون: Buca, D, Di Mascio, D, Khalil, A, Acharya, G, Van Mieghem, T, Hack, K, Murata, M, Anselem, O, D'Amico, A, Muzii, L, Liberati, M, Nappi, L, D'Antonio, F

المصدر: American journal of perinatology. 39(03):243-251

مصطلحات موضوعية: Medicin och hälsovetenskap

الوصول الحر: http://kipublications.ki.se/Default.aspx?queryparsed=id:148883318Test

المؤلفون: Buca, D, Winberg, P, Rizzo, G, Khalil, A, Liberati, M, Makatsariya, A, Greco, F, Nappi, L, Acharya, G, D'Antonio, F

المصدر: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 35(3):598-606

مصطلحات موضوعية: Medicin och hälsovetenskap

الوصول الحر: http://kipublications.ki.se/Default.aspx?queryparsed=id:142961294Test

المؤلفون: Di Mascio D., Rizzo G., Khalil A., D'Antonio F., Giancotti A., Manganaro L., Visentin S., Cosmi E., Prefumo F., Stampalija T., D'Ambrosio V., Brunelli R., Liberati M., Buca D., Matarrelli B., D'Amico A., Oronzii L., Tinari S., Caulo M., Gentile L., Fantasia I., Mappa I., Maruotti G. M., Saccone G., Carbone L., Sarno L., Bracalente G., Bertucci E., Sileo F. G., Pellegrino M., De Santis M., Lanzone A., Pinelli L., Murru F., Trincia E., Pajno C., Sorrenti S., Vasciaveo L., Nappi L., Greco P.

المساهمون: Di Mascio, D., Rizzo, G., Khalil, A., D'Antonio, F., Giancotti, A., Manganaro, L., Visentin, S., Cosmi, E., Prefumo, F., Stampalija, T., D'Ambrosio, V., Brunelli, R., Liberati, M., Buca, D., Matarrelli, B., D'Amico, A., Oronzii, L., Tinari, S., Caulo, M., Gentile, L., Fantasia, I., Mappa, I., Maruotti, G. M., Saccone, G., Carbone, L., Sarno, L., Bracalente, G., Bertucci, E., Sileo, F. G., Pellegrino, M., De Santis, M., Lanzone, A., Pinelli, L., Murru, F., Trincia, E., Pajno, C., Sorrenti, S., Vasciaveo, L., Nappi, L., Greco, P.

مصطلحات موضوعية: CMV, cytomegaloviru, hearing lo, infection, MRI, neurosonography, ultrasound

الوصف: Objective: To investigate the role of fetal brain magnetic resonance imaging (MRI) in detecting associated anomalies in fetuses with congenital cytomegalovirus (CMV) infection and normal neurosonography. Methods: This was a multicenter, retrospective cohort study of patients examined between 2012 and 2021 in 11 referral fetal medicine centers in Italy. Inclusion criteria were fetuses with congenital CMV infection diagnosed by polymerase chain reaction analysis of amniotic fluid, pregnancies that underwent detailed multiplanar ultrasound assessment of the fetal brain as recommended by the International Society of Ultrasound in Obstetrics and Gynecology, maternal age ≥ 18 years, normal fetal karyotype and MRI performed within 3 weeks after the last ultrasound examination. The primary outcome was the rate of central nervous system (CNS) anomalies detected exclusively on MRI and confirmed after birth or autopsy in fetuses with a prenatal diagnosis of congenital CMV infection and normal neurosonography at diagnosis. Additional CNS anomalies were classified into anomalies of the ventricular and the periventricular zone, intracranial calcifications in the basal ganglia or germinal matrix, destructive encephalopathy in the white matter, malformations of cortical development, midline anomalies, posterior fossa anomalies and complex brain anomalies. We evaluated the relationship between the incidence of structural CNS malformations diagnosed exclusively on fetal MRI and a number of maternal and gestational characteristics. Univariate and multivariate logistic regression analyses were used to identify and adjust for potential independent predictors of the MRI diagnosis of fetal anomalies. Results: The analysis included 95 fetuses with a prenatal diagnosis of congenital CMV infection and normal neurosonography referred for prenatal MRI. The rate of structural anomalies detected exclusively at fetal MRI was 10.5% (10/95). When considering the type of anomaly, malformations of cortical development were detected on MRI in ...

وصف الملف: ELETTRONICO

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36056700; info:eu-repo/semantics/altIdentifier/wos/WOS:000950613100008; volume:61; issue:1; firstpage:67; lastpage:73; numberofpages:7; journal:ULTRASOUND IN OBSTETRICS & GYNECOLOGY; https://hdl.handle.net/11564/824927Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85143275638

الإتاحة: https://doi.org/10.1002/uog.26054Test
https://hdl.handle.net/11564/824927Test

المؤلفون: Nappi, L, Thi, M, Adra, N, Hamilton, RJ, Leao, R, Lavoie, JM, Soleimani, M, Eigl, BJ, Chi, K, Gleave, M, So, A, Black, PC, Bell, R, Daneshmand, S, Cary, C, Masterson, T, Einhorn, L, Nichols, C, Kollmannsberger, C

مصطلحات موضوعية: MicroRNAs, Neoplasias Embrionárias de Células Germinativas, Neoplasias Testiculares, Teratoma, Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms

الوصف: Active germ cell malignancies express high levels of specific circulating micro-RNAs (miRNAs), including miR-371a-3p (miR371), which is undetectable in teratoma. Teratoma markers are urgently needed for theselection of patients and treatments because of the risk of malignant transformation and growing teratoma syndrome. To assess the accuracy of plasma miR375 alone or in combination with miR371 in detecting teratoma, 100 germ cell tumor patients, divided into two cohorts, were enrolled in a prospective multi-institutional study. In the discovery cohort, patients with pure teratoma and with no/low risk of harboring teratoma were compared; the validation cohort included patients with confirmed teratoma, active germ cell malignancy, or complete response after chemotherapy. The area under the receiver operating characteristic curve values for miR375, miR371, and miR371-miR375 were, respectively, 0.93 (95% confidence interval [CI]: 0.87-0.99), 0.59 (95% CI: 0.44-0.73), and 0.95 (95% CI: 0.90-0.99) in the discovery cohort and 0.55 (95% CI: 0.36-0.74), 0.74 (95% CI: 0.58-0.91), and 0.77 (95% CI: 0.62-0.93) in the validation cohort. Our study demonstrated that the plasma miR371-miR375 integrated evaluation is highly accurate to detect teratoma. PATIENT SUMMARY: The evaluation of two micro-RNAs (miR375-miR371) in the blood of patients with germ cell tumors is promising to predict teratoma. This test could be particularly relevant to the identification of teratoma in patients with postchemotherapy residual disease. ; info:eu-repo/semantics/publishedVersion

العلاقة: Eur Urol . 2021 Jan;79(1):16-19; http://hdl.handle.net/10400.26/43624Test

الإتاحة: https://doi.org/10.1016/j.eururo.2020.10.024Test
http://hdl.handle.net/10400.26/43624Test

المؤلفون: Stabile G., Carlucci S., De Bonis L., Sorrentino F., Nappi L., Ricci G.

المساهمون: Stabile, G., Carlucci, S., De Bonis, L., Sorrentino, F., Nappi, L., Ricci, G.

مصطلحات موضوعية: double knot, fetal risk, true knot, umbilical cord knot

الوصف: True knots of the umbilical cord (UC) are a rare occurrence and are reported in 0.4–1.2% of deliveries. The compression of true knot of the UC can cause obstruction of the fetal circulation, leading to intra‐uterine growth retardation or fetal death. Predisposing factors for the genesis of the true UC knot are numerous and include all the conditions, which lead to a relatively large uterine volume. This situation may predispose to free and excessive fetal movements. Although not all true knots lead to perinatal complications, they have been associated with adverse pregnancy outcomes, including fetal distress, fetal hypoxia, intra‐uterine growth restriction (IUGR), long‐term neurological damage, caesarean delivery and stillbirth. We present a rare case of operative delivery with vacuum in a multiparous woman at term of pregnancy with a double true knot of the UC. As in most cases, the diagnosis was made after delivery, as there were no fetal symptoms during pregnancy. Some authors assume that 3D power sonography may be useful in the diagnosis of true UC knots. However, 3D power Doppler cannot be considered as a definitive method. There are no specific prenatal indications to induce the physician to look for ultrasound signs suggestive of umbilical true knot. Some studies argue that cases of fetal death and fetal risk are directly related to the number of knots. We also support this thesis, even if further observational and retrospective studies are needed to demonstrate it.

وصف الملف: ELETTRONICO

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35743964; info:eu-repo/semantics/altIdentifier/wos/WOS:000816290500001; volume:58; issue:6; firstpage:"-"; lastpage:"-"; numberofpages:6; journal:MEDICINA; https://hdl.handle.net/11368/3040010Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85131384413; https://www.mdpi.com/1648-9144/58/6/703Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229958Test/

الإتاحة: https://doi.org/10.3390/medicina58060703Test
https://hdl.handle.net/11368/3040010Test
https://www.mdpi.com/1648-9144/58/6/703Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9229958Test/

المؤلفون: Nappi L, Angioni S, De Feo V, Greco P, Stabile G, Greco F, D'Alterio MN, Sorrentino F

المساهمون: Nappi, L, Angioni, S, De Feo, V, Greco, P, Stabile, G, Greco, F, D'Alterio, Mn, Sorrentino, F

مصطلحات موضوعية: Endometrial hyperplasia (EH), Office hysteroscopy (OH), Dilation and curettage (D&, C), Transvaginal ultrasound (TVUS), Endometrial biopsy (EB), Endometrial carcinoma

الوصف: Background: Endometrial hyperplasia (EH) is considered a heterogeneous pre-neoplastic clinical entity characterized by an abnormal glandular proliferation, with less than half of the tissue area occupied by the stroma. The aim of this retrospective study was to evaluate the correlation between the histological diagnosis of atypical endometrial hyperplasia (AEH) obtained through office hysteroscopy (OH) or uterine dilation and curettage (D&C) and the definitive histological evaluation after hysterectomy. Methods: Among 112 patients with atypical EH, 45 (40%) underwent hysteroscopy and 67 (60%) curettage. Results: The diagnostic accuracy of OH was very high: in particular, it showed a diagnostic coincidence in 87% of cases with the definitive histological diagnosis through hysteroscopy. The curettage, instead, had diagnostic coincidence only in 14% of cases. Conclusion: Office hysteroscopy is the ideal procedure for both diagnosis and follow-up of endometrial hyperplasia.

العلاقة: info:eu-repo/semantics/altIdentifier/wos/WOS:000778812100024; volume:49; issue:1; firstpage:1; lastpage:5; numberofpages:5; journal:CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY; https://hdl.handle.net/11584/326867Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85124139561; https://www.imrpress.com/journal/CEOG/49/1/10.31083/j.ceog4901024Test

الإتاحة: https://doi.org/10.31083/j.ceog4901024Test
https://hdl.handle.net/11584/326867Test