المؤلفون: Shang, Yao, Lavender Yuen-Nam, Fan, Eric Wing-Fai, Lam

المصدر: Seminars in Cancer Biology

مصطلحات موضوعية: IGF, insulin growth factor, MRN, MER11-RAD50-NBS1, Skp2, S-phase kinase-associated protein 2, DNA Repair, ER, estrogen receptor, FasL, fas ligand, GICs, glioma-initiating cells, TCF/LEF, T-cell factor/lymphoid enhancer factor, NBS1, Nijmegen breakage syndrome 1, ATM, Ataxia-telangiectasia mutated, FHRE, forkhead response element, AURKA, aurora kinase A, Mst1, macrophage stimulating 1, ERK, extracellular signal-regulated kinase, Bim, B-cell lymphoma 2 interacting mediator, RTKs, receptor tyrosine kinases, Neoplasms, XRCC1, X-ray cross-complementing group 1, Cell Self Renewal, BER, base excision repair, MDR1, multidrug resistance protein 1, AMPK, adenosine monophosphate-activated protein kinase, OTUB1, OUT domain-containing ubiquitin aldehyde-binding protein 1, Forkhead Box Protein O3, Fox, forkhead box, ABCB1, ATP-binding cassette sub-family B member 1, PI3K, phosphatidylinositol 3-kinase, TRAIL, tumour necrosis factor-related apoptosis inducing ligand, TKIs, tyrosine kinase inhibitors, VEGF, vascular endothelial growth factor, Gene Expression Regulation, Neoplastic, PIP3, phosphatidylinositol- 3,4,5-trisphosphate, GADD45, DNA damage-inducible protein 45, AML, acute myeloid leukaemia, SOD-2, superoxide dismutase, IFNɣ, interferon-ɣ, PKB, protein kinase B, CSCs, cancer stem cells, NAMPT, nicotinamide-phosphribosyltransferase, Antineoplastic Agents, BRCA1, breast cancer susceptibility gene product 1, MMR, mismatch repair, mTOR, mammalian target of rapamycin, SSBs, single-strand breaks, ER+ve, estreogen receptor positive, Article, DDR, DNA damage response, DSBs, double strands breaks, ESR1, estrogen receptor alpha gene, EXO1, exonuclease 1, miRs, Micro-RNAs, ROS, reactive oxygen species, NER, nucleotide excision repair, MCL, mantle cell lymphoma, MEK, mitogen-activated protein kinase kinase, Humans, Cks1, cyclin-dependent kinases regulatory subunit 1, SCs, stem cells, Cell Proliferation, CML, chronic myeloid leukaemia, EGF, epidermal growth factor, Forkhead Box Protein M1, EGFR, epidermal growth factor receptor, PA, Psammaplysene A, ChIP-seq, chromatin immunoprecipitation with massively parallel DNA sequencing, Drug Resistance, Neoplasm, BRCA2, breast cancer-associated gene 2, NHEJ, non-homologous end joining, BRIP1, BRCA1-interacting protein-terminal helicase 1, Rb2, retinoblastoma-related p130, HR, homologous recombination, HCC, hepatocellular carcinoma, JNK/SAPK, c-Jun N-terminal kinase/stress activated protein kinase, Sox1, sex determining region Y box 2, PDK, phosphoinositide-dependent kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::251efc5425717cea78c8bea6a5fc363bTest
https://pubmed.ncbi.nlm.nih.gov/29180117Test

المؤلفون: Senthiladipan, Venkatachalam, Esther, Mettler, Christian, Fottner, Matthias, Miederer, Bernd, Kaina, Matthias M, Weber

المصدر: Clinical and Translational Radiation Oncology

مصطلحات موضوعية: SF, surviving fractions, MVP, major vault protein, Colorectal carcinmoma, RAD 51, IGF-1R/KR, kinase-deficient IGF-1R, IRS-1, insulin receptor substrate 1, BRCA2, Article, PTEN, phosphatase and tensin homolog, BAX, BCL-2-associated X, Radiosensitivity, IGF-1R, insulin-like growth factor 1 receptor, NHEJ, non-homologous end joining, Dominant negative mutant, Insulin-like growth factor-1 receptor, HRR, homologous recombination repair, BCL-2, B-cell lymphoma 2, Caco-2-KR4, IGF-1R/KR clone number 4

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::0630bc24e30e8200864c2b80f7999bccTest
https://pubmed.ncbi.nlm.nih.gov/29594222Test

المؤلفون: Díaz Merayo, Celia

المساهمون: Casafont Parra, Íñigo, Universidad de Cantabria

المصدر: UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)

مصطلحات موضوعية: NHEJ (Non Homologous End Joining), DSBs (Double-Strand DNA Breaks), SUMO, Neurodegenerative diseases, Alzheimer, HRR (Homologous Recombination Repair), Parkinson, Ubiquitina, Tau, Proteasoma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::30083371a3cbf7ff4eadf24a5169c814Test
http://hdl.handle.net/10902/11622Test

المؤلفون: Sabine Schmitz, Yvonne Lorat, Nadine Schuler, Claudia E. Rübe, Jan Palm

المصدر: Clinical and translational radiation oncology 7, 71-78 (2017). doi:10.1016/j.ctro.2017.10.004
Clinical and Translational Radiation Oncology
Clinical and Translational Radiation Oncology, Vol 7, Iss, Pp 71-78 (2017)

مصطلحات موضوعية: 0301 basic medicine, Genome instability, Genomic instability, Pathology, medicine.medical_specialty, DNA repair, DNA damage, R895-920, Craniospinal Irradiation, Article, Medical physics. Medical radiology. Nuclear medicine, 03 medical and health sciences, Germline mutation, LFS, Li-Fraumeni syndrome, medicine, Radiology, Nuclear Medicine and imaging, SEM, scanning electron microscopy, Li-Fraumeni syndrome, ddc:610, TEM, transmission electron microscopy, DSBs, double-strands breaks, RC254-282, P53, business.industry, CPC, choroid plexus carcinoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Cancer, Craniospinal irradiation, medicine.disease, 53BP1, 53 Binding Protein 1, Hematopoiesis, NHEJ, non-homologous end-joining, γH2AX, phosporylated histone H2AX, 030104 developmental biology, medicine.anatomical_structure, Oncology, Li–Fraumeni syndrome, mFISH, multicolour fluorescence in-situ hybridization, Bone marrow, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03caa63d129c0cc1496a9436a5e3c549Test
https://juser.fz-juelich.de/record/839969Test

المؤلفون: Bryce W.Q. Tan, Upadhyayula Sai Srinivas, Anand D. Jeyasekharan, Balamurugan A. Vellayappan

المصدر: Redox Biology, Vol 25, Iss, Pp-(2019)
Redox Biology

مصطلحات موضوعية: MRN, Mre11-Rad50-Nbs1, 0301 basic medicine, DNA Repair, medicine.medical_treatment, Clinical Biochemistry, Mdm2, Mouse double minute 2, Apoptosis, H2O2, Hydrogen peroxide, Genotoxic Stress, DNA damage response, Biochemistry, SOD, Superoxide dismutase, 0302 clinical medicine, Neoplasms, HER-2, human epidermal growth factor receptor 2, lcsh:QH301-705.5, ATRIP, ATR interacting protein, Double strand, chemistry.chemical_classification, lcsh:R5-920, Chemistry, OXPHOS, Oxidative phosphorylation, ROS, Cdc25, Cell division cycle 25, dNTP, deoxyribonucleotide triphosphate, PLK1, Polo-like kinase 1, BER, Base excision repair, NADPH, Nicotinamide adenine dinucleotide phosphate, ICD, Immunogenic cell death, lcsh:Medicine (General), BSO, Buthionine sulfoximine, ATM, Ataxia telangiectasia mutated, DNA damage, NRF-2, Nuclear factor (erythroid-derived 2)-like 2, ATR, Ataxia telangiectasia mutated and Rad3 related, HR, Homologous recombination, Context (language use), DDR, Article, DDR, DNA damage response, 03 medical and health sciences, RPA, Replication protein A, medicine, Animals, Humans, Chemotherapy, MAPK, Mitogen-activated protein kinases, NCF2, Neutrophil Cytosolic Factor 2, Reactive oxygen species, PPP, Pentose phosphate pathway, XRCC4, X-ray repair cross-complementing protein 4, Radiotherapy, DNA PK, DNA-dependent protein kinase, Organic Chemistry, Cancer, NHEJ, Non-homologous end joining, medicine.disease, ETC, Electron transport chain, mtROS, Mitochondrial ROS, Radiation therapy, DSB, Double strand break, 030104 developmental biology, lcsh:Biology (General), AML, Acute myeloid leukemia, Cancer research, Tumor Suppressor Protein p53, Reactive Oxygen Species, 030217 neurology & neurosurgery, DNA Damage, ROS, Reactive oxygen species

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88506b3a62a7fc5a96ea3bf0d616e55eTest
https://doi.org/10.1016/j.redox.2018.101084Test

المؤلفون: Aaron Wilson, Vijay Menon, Asim Alam, Larisa Litovchick, Vasily A. Yakovlev, Zubair Khan

المصدر: Redox Biology
Redox Biology, Vol 24, Iss, Pp-(2019)

مصطلحات موضوعية: 0301 basic medicine, Synthetic lethality, DNA Repair, medicine.medical_treatment, Clinical Biochemistry, Radiation Tolerance, Biochemistry, Ionizing radiation, 0302 clinical medicine, Radiation, Ionizing, lcsh:QH301-705.5, PARP inhibitors, BER, base excision repair, Sensitization, lcsh:R5-920, BRCA1 Protein, Chemistry, MTM, mean tail moment, BRCA, breast cancer type susceptibility proteins, medicine.anatomical_structure, Homologous recombination repair, PARP inhibitor, FITC, fluorescein isothiocyanate, lcsh:Medicine (General), Research Paper, PARP, poly (ADP-ribose) polymerase, Signal Transduction, PARPi, poly (ADP-ribose) polymerase inhibitor, DNA damage, Nitric oxide donors, MMR, mismatch repair, SSB, single-strand break, Poly(ADP-ribose) Polymerase Inhibitors, 03 medical and health sciences, NER, nucleotide excision repair, Cell Line, Tumor, RBL2, Retinoblastoma-like protein 2, medicine, Humans, DSB, double-strand break, Edetic Acid, Tumor microenvironment, Chemotherapy, Retinoblastoma-Like Protein p130, Organic Chemistry, PI, Propidium Iodide, Cancer, medicine.disease, 030104 developmental biology, lcsh:Biology (General), NHEJ, non-homologous end joining, Cancer research, IR, ionizing radiation, Benzimidazoles, HRR, homologous recombination repair, SD, standard deviation, Synthetic Lethal Mutations, 030217 neurology & neurosurgery, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1895e2b42e85aea0604778704956607Test
https://doi.org/10.1016/j.redox.2019.101169Test

المؤلفون: Díaz Merayo, Celia

المساهمون: Casafont Parra, Íñigo, Universidad de Cantabria

مصطلحات موضوعية: Alzheimer, Parkinson, Neurodegenerative diseases, SUMO, Proteasoma, Ubiquitina, Tau, HRR (Homologous Recombination Repair), NHEJ (Non Homologous End Joining), DSBs (Double-Strand DNA Breaks)

العلاقة: http://hdl.handle.net/10902/11622Test

الإتاحة: http://hdl.handle.net/10902/11622Test

المؤلفون: Pallavi, Agarwal, Stephen P, Jackson

المصدر: Cancer Letters

مصطلحات موضوعية: DNA End-Joining Repair, Time Factors, Chemotherapeutics, Chemical probes, DSB, double strand break, Apoptosis, Phleomycins, Transfection, DDR, DNA damage response, PI, propidium iodide, Cancer epigenetics, SGC, Structural Genomics Consortium, Histocompatibility Antigens, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Humans, Topoisomerase II Inhibitors, DNA Breaks, Double-Stranded, Enzyme Inhibitors, Cell Proliferation, Etoposide, ATM, ataxia telangiectasia mutated, Antibiotics, Antineoplastic, KO, knockout, Dose-Response Relationship, Drug, XRCC4, X-ray repair cross-complementing protein 4, UNC0638, Histone-Lysine N-Methyltransferase, Original Articles, HCT116 Cells, WT, wild-type, ATR, ataxia telangiectasia and Rad3-related protein, NHEJ, non-homologous end joining, Quinazolines, RNA Interference, Tumor Suppressor Protein p53, Non-homologous end joining, Signal Transduction, IC50, inhibitory concentration 50%

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::7c85a52dccf831005b227bfe5d3f026aTest
https://pubmed.ncbi.nlm.nih.gov/27431310Test

المؤلفون: Keith W. Caldecott, Geoffrey Kelly, Timothy J. Nott, Stephen J. Smerdon, Stuart L. Rulten, A.L. Cherry

المصدر: Print: 1568-7864
DNA Repair

مصطلحات موضوعية: ZF, zinc finger, DNA Repair, BRCT, BRCA1 C-terminal, APLF, aprataxin- and PNK-like factor, Crystallography, X-Ray, Biochemistry, APTX, aprataxin, XRCC1, DNA-PKcs, catalytic subunit of DNA-dependent protein kinase, DNA-(Apurinic or Apyrimidinic Site) Lyase, Poly-ADP-Ribose Binding Proteins, Phosphorylation, Casein Kinase II, PARP-1, poly(ADP-ribose)polymerase 1, ITC, isothermal titration calorimetry, Nuclear Proteins, 3. Good health, DNA-Binding Proteins, NHEJ, non-homologous end-joining, HIT, Histidine triad, Phosphotransferases (Alcohol Group Acceptor), DNA break repair, FHA, forkhead-associated, FHA domain, Casein kinase 1, Casein kinase 2, XRCC1, X-ray repair cross-complementing protein 1, DNA repair, Molecular Sequence Data, DNA-damage signalling, Biology, DNA-binding protein, Article, CC, coiled-coil, QH301, PNKP, polynucleotide kinase phosphatase, Humans, Amino Acid Sequence, NTD, N-terminal domain, Binding site, Molecular Biology, Nuclear Magnetic Resonance, Biomolecular, Aprataxin, Binding Sites, XRCC4, X-ray repair cross-complementing protein 4, Cell Biology, QP, Protein Structure, Tertiary, CK2, casein kinase 2, DNA Repair Enzymes, X-ray Repair Cross Complementing Protein 1, DNA Damage

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3b0013f35e37b430ed595faf11ff76aTest
https://eprints.worc.ac.uk/4125/1/Cherry_et_al_2015_DNA_Repair.pdfTest

المؤلفون: Zuoyan Zhu, Xiaojuan Cui, Jun Dai, Wei Hu

المصدر: International Journal of Biological Sciences

مصطلحات موضوعية: Embryo, Nonmammalian, DNA Repair, DNA repair, Concatemer, Transgene, Genetic Vectors, Green Fluorescent Proteins, Cytomegalovirus, Applied Microbiology and Biotechnology, Green fluorescent protein, Animals, Genetically Modified, chemistry.chemical_compound, Sticky and blunt ends, Animals, DNA Breaks, Double-Stranded, Promoter Regions, Genetic, Molecular Biology, Zebrafish, Ecology, Evolution, Behavior and Systematics, Reporter gene, biology, fungi, Cell Biology, biology.organism_classification, Molecular biology, Non-homologous end joining, NHEJ (non-homologous end joining), chemistry, Research Paper, DSB (double strand breaks), Plasmids, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ea21b78dd205371b53dc939650013aTest
https://doi.org/10.7150/ijbs.6.756Test