المؤلفون: Shen, Xiao-Yong, Xu, Hong-Qin, Gerdroodbary, M. Barzegar, Valiallah Mousavi, S., Musa Abazari, Amir, Imani, S. Misagh

المصدر: International Journal of Modern Physics C: Computational Physics & Physical Computation; Mar2022, Vol. 33 Issue 1, p1-18, 18p

مصطلحات موضوعية: INTRACRANIAL aneurysms, FLOW simulations, CEREBRAL arteries, BLOOD viscosity, DISEASE progression

مستخلص: The morbidity and mortality of aneurysm rupture have raised significantly in current years. In this research, numerical investigations have been performed to disclose the impacts of hemodynamic on the breach and growth of the Intracranial Aneurysms (IA) in the middle cerebral artery (MCA). To perform this research, computational fluid dynamic (CFD) methodology is employed to model the non-Newtonian blood stream through the IA. 3D model of IA is chosen for the analysis blood flow. Wall shear stress (WSS) was evaluated and compared at the high-risk region, where the probability of rupture is high. This study offers precise information and insight about the influence of blood viscosity and velocity on the danger of the aneurysm rupture in the MCA. Our outcomes show that the location and orientation of the aneurysm have direct impacts on the growth of the aneurysm. The main attention of this research is to reveal more vibrant facts about the primary reasons for the rupture of the aneurysm and present connection among the rupture points and the local hemodynamic features. This work tries to demonstrate the critical area on the aneurysm surface by analyzing the WSS and pressure distribution. [ABSTRACT FROM AUTHOR]

: Copyright of International Journal of Modern Physics C: Computational Physics & Physical Computation is the property of World Scientific Publishing Company and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Shen, Xiao-Yong, Gerdroodbary, M. Barzegar, Poozesh, Amin, Musa Abazari, Amir, Imani, S. Misagh

المصدر: International Journal of Modern Physics C: Computational Physics & Physical Computation; Nov2021, Vol. 32 Issue 11, p1-18, 18p

مصطلحات موضوعية: INTRACRANIAL aneurysms, BLOOD flow, CARDIOVASCULAR diseases, CARDIOVASCULAR system, FLOW velocity

مستخلص: In recent decades, cardiovascular disease and stroke are recognized as the most important reason for the high death rate. Irregular bloodstream and the circulatory system are the main reason for this issue. In this paper, Computational Fluid dynamic method is employed to study the impacts of the flow pattern inside the cerebral aneurysm for detection of the hemorrhage of the aneurysm. To achieve a reliable outcome, blood flow is considered as a non-Newtonian fluid with a power-law model. In this study, the influence of the blood viscosity and velocity on the pressure distribution and average wall shear stress (AWSS) are comprehensively studied. Moreover, the flow pattern inside the aneurysm is investigated to obtain the high-risk regions for the rupture of the aneurysm. Our results indicate that the wall shear stress (WSS) increases with increasing blood flow velocity. Furthermore, the risk of aneurysm rupture is considerably increased when the AWSS increases more than 0.6. Indeed, the blood flow with high viscosity expands the high-risk region on the wall of the aneurysm. Blood flow indicates that the angle of the incoming bloodstream is substantially effective in the high-risk region on the aneurysm wall. The augmentation of the blood velocity and vortices considerably increases the risk of hemorrhage of the aneurysm. [ABSTRACT FROM AUTHOR]

: Copyright of International Journal of Modern Physics C: Computational Physics & Physical Computation is the property of World Scientific Publishing Company and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)