المؤلفون: Maruyama, Hiroki, Miyata, Kaori, Mikame, Mariko, Taguchi, Atsumi, Guili, Chu, Shimura, Masaru, Murayama, Kei, Inoue, Takeshi, Yamamoto, Saori, Sugimura, Koichiro, Tamita, Koichi, Kawasaki, Toshihiro, Kajihara, Jun, Onishi, Akifumi, Sugiyama, Hitoshi, Sakai, Teiko, Murata, Ichijiro, Oda, Takamasa, Toyoda, Shigeru, Hanawa, Kenichiro, Fujimura, Takeo, Ura, Shigehisa, Matsumura, Mimiko, Takano, Hideki, Yamashita, Satoshi, Matsukura, Gaku, Tazawa, Ryushi, Shiga, Tsuyoshi, Ebato, Mio, Satoh, Hiroshi, Ishii, Satoshi

المصدر: Genetics in Medicine ; volume 21, issue 1, page 44-52 ; ISSN 1098-3600

مصطلحات موضوعية: Genetics (clinical)

الإتاحة: https://doi.org/10.1038/gim.2018.31Test
https://www.nature.com/articles/gim201831Test
https://www.nature.com/articles/gim201831.pdfTest
https://api.elsevier.com/content/article/PII:S1098360021000745?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1098360021000745?httpAccept=text/plainTest

المؤلفون: Maruyama, Hiroki, Miyata, Kaori, Mikame, Mariko, Taguchi, Atsumi, Guili, Chu, Shimura, Masaru, Murayama, Kei, Inoue, Takeshi, Yamamoto, Saori, Sugimura, Koichiro, Tamita, Koichi, Kawasaki, Toshihiro, Kajihara, Jun, Onishi, Akifumi, Sugiyama, Hitoshi, Sakai, Teiko, Murata, Ichijiro, Oda, Takamasa, Toyoda, Shigeru, Hanawa, Kenichiro, Fujimura, Takeo, Ura, Shigehisa, Matsumura, Mimiko, Takano, Hideki, Yamashita, Satoshi, Matsukura, Gaku, Tazawa, Ryushi, Shiga, Tsuyoshi, Ebato, Mio, Satoh, Hiroshi, Ishii, Satoshi

المصدر: Genetics in Medicine ; volume 21, issue 2, page 512-515 ; ISSN 1098-3600

مصطلحات موضوعية: Genetics (clinical)

الإتاحة: https://doi.org/10.1038/s41436-018-0125-2Test
http://www.nature.com/articles/s41436-018-0125-2Test
http://www.nature.com/articles/s41436-018-0125-2.pdfTest
https://api.elsevier.com/content/article/PII:S1098360021046116?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1098360021046116?httpAccept=text/plainTest

المؤلفون: Tanada, Yohei, Okuda, Junji, Kato, Takao, Minamino-Muta, Eri, Murata, Ichijiro, Soga, Tomoyoshi, Shioi, Tetsuo, Kimura, Takeshi

المساهمون: Japan Society for the Promotion of Science

المصدر: PeerJ ; volume 5, page e3352 ; ISSN 2167-8359

الوصف: Background The kidney is always subjected to high metabolic demand. The aim of this study was to characterize metabolic profiles of a rat model of chronic kidney disease (CKD) with cardiorenal syndrome (CRS) induced by prolonged hypertension. Methods We used inbred male Dahl salt-sensitive (DS) rats fed an 8% NaCl diet from six weeks of age (high-salt; HS group) or a 0.3% NaCl diet as controls (low-salt; LS group). We analyzed function, pathology, metabolome, and the gene expression related to energy metabolism of the kidney. Results DS rats with a high-salt diet showed hypertension at 11 weeks of age and elevated serum levels of creatinine and blood urea nitrogen with heart failure at 21 weeks of age. The fibrotic area in the kidneys increased at 21 weeks of age. In addition, gene expression related to mitochondrial function was largely decreased. The levels of citrate and isocitrate increased and the gene expression of alpha-ketoglutaratedehydrogenase and succinyl-CoA synthetase decreased; these are enzymes that metabolize citrate and isocitrate, respectively. In addition, the levels of succinate and acetyl Co-A, both of which are metabolites of the tricarboxylic acid (TCA) cycle, decreased. Conclusions DS rats fed a high-salt diet were deemed a suitable model of CKD with CRS. Gene expression and metabolites related to energy metabolism and mitochondria in the kidney significantly changed in DS rats with hypertension in accordance with the progression of renal injury.

الإتاحة: https://doi.org/10.7717/peerj.3352Test
https://peerj.com/articles/3352.pdfTest
https://peerj.com/articles/3352.xmlTest
https://peerj.com/articles/3352.htmlTest

المؤلفون: Yoshida, Gakuro, Kawasaki, Masanori, Murata, Ichijiro, Hayakawa, Yuka, Aoyama, Takuma, Miyazaki, Nagisa, Yamada, Yoshihisa, Nishigaki, Kazuhiko, Arai, Yoshie, Suzuki, Fumiaki, Minatoguchi, Shinya

المصدر: Biomarker Research ; volume 3, issue 1 ; ISSN 2050-7771

مصطلحات موضوعية: Biochemistry (medical), Clinical Biochemistry, Molecular Medicine

الإتاحة: https://doi.org/10.1186/s40364-015-0044-1Test

المؤلفون: Kleophas, Werner, Bieber, B, Robinson, Bm, Duttlinger, J, Fliser, D, Lonneman, G, Rump, Lc, Pisoni, Rl, Port, Fk, Reichel, H, Daniela, Radulescu, Ciocalteu, Alexandru, Checherita, Ionel Alexandru, Peride, Ileana, Spataru, Daniela Margareta, Niculae, Andrei, Laetitia, Koppe, Amna, Klich, Laurence, Dubourd, Aoumeur, Hadj-Aissa, Flamant, Martin, Haymann, Jean-Philippe, Letavernier, Emmanuel, Vidal-Petiot, Emmanuelle, Boffa, Jean-Jacques, Vrtovsnik, Francois, Bianco, Francesco, Pessolano, Giuseppina, Carraro, Michele, Panzetta, Giovanni Oliviero, Ebert, Natalie, Gaedeke, Jens, Jakob, Olga, Kuhlmann, Martin, Martus, Peter, Van der Giet, Markus, Sch㥦ner, Elke, Khan, Izhar, Law, Yvonne, Turgutalp, Kenan, Ozhan, Onur, Gok Oguz, Ebru, Kiykim, Ahmet, Donadio, Carlo, Hatmi, Zinat Nadia, Mahdavi-Mazdeh, Mitra, Morales, Enrique, Gutierrez-Millet, Victor, Rojas-Rivera, Jorge, Huerta, Ana, Gutierrez, Eduardo, Gutierrez-Solis, Elena, Polanco, Natalia, Caro, Jara, Gonzà¥z, Esther, Praga, Manuel, Marco Mayayo, MarìPaz, Valdivielso, Josçanuel, Martì­¥z, Montserrat, Fernàez Giràez, Elvira, Obrador, Gregorio, Olvera, Nadia, Ortiz de la Pe, Daniela, Gutié±ez, Veró£a, Villa, Antonio, Redal-Baigorri, Bel, Sombolos, Konstantinos, Tsakiris, Dimitris, Boletis, John, Vlahakos, Dimitrios, Siamopoulos, Konstantinos, Vargiemezis, Vassilios, Nikolaidis, Pavlos, Iatrou, Christos, Dafnis, Evgenios, Argyropoulos, Christos, Xynos, Konstantinos, Schock-Kusch, Daniel, Shulhevich, Yury, Geraci, Stefania, Hesser, Juergen, Stsepankou, Dzmitry, Neudecker, Sabine, Koenig, Stefan, Hoecklin, Friederike, Pill, Johannes, Gretz, Norbert, Schweda, Frank, Schreiber, Andrea, Kudo, Kosuke, Konta, Tsuneo, Choi, Seung Ok, Kim, Jae Seok, Kim, Min Keun, Yang, Jae Won, Han, Byoung Geun, Delanaye, Pierre, Cavalier, Etienne, Masson, Ingrid, Mehdi, Manolie, Nicolas, Maillard, Lambermont, Bernard, Dubois, Bernard, Damas, Pierre, Krzesinski, Jean-Marie, Morel, Jerome, Lautrette, Alexandre, Christophe, Mariat, Gagneux-Brunon, Amandine, Anne, Fresard, Fr襩ric, Lucht, Bevc, Sebastjan, Ekart, Robert, Hojs, Radovan, Gorenjak, Maksimiljan, Puklavec, Ludvik, Hashimoto, Norihiro, Suzuki, Akira, Mitsumoto, Kensuke, Shimizu, Morihiro, Niihata, Kakuya, Kawabata, Akihiro, Sakaguchi, Yusuke, Hayashi, Terumasa, Shoji, Tatsuya, Okada, Noriyuki, Tsubakihara, Yoshiharu, Hamano, Takayuki, Nakano, Chikako, Fujii, Naohiko, Obi, Yoshitugu, Mikami, Satoshi, Inoue, Kazunori, Matsui, Isao, Isaka, Yoshitaka, Rakugi, Hiromi, Edvardsson, Vidar, Siguron, Baldur, Thorsteinsdottir, Margret, Palsson, Runolfur, Matsumoto, Jun, Miyazaki, Nagisa, Murata, Ichijiro, Yoshida, Gakuro, Morishita, Kentaro, Ushikoshi, Hiroaki, Nishigaki, Kazuhiko, Ogura, Shinji, Minatoguchi, Shinya, Werneke, Ursula, Ott, Michael, Salander-Renberg, Ellinor, Taylor, David, Stegmayr, Bernd, Surel, Stanislav, Wenzlova, Martina, Silva Junior, Geraldo, Vieira, Ana Patricia, Couto Bem, Amanda, Alves, Marilia, Torres, Alba, Meneses, Gdayllon, Martins, Alice, Liborio, Alexandre, Daher, Elizabeth, Gluhovschi, Gheorghe, Modilca, Mirela, Daminescu, Liviu, Gluhovschi, Cristina, Velciov, Silvia, Petrica, Ligia, Gadalean, Florica, Balgradean, Cristian, Schmeiser, Heinz H., Kolesnyk, Mykola, Stepanova, Natalia, Surzhko, Liudmyla, Stashevska, Natalia, Filiopoulos, Vassilis, Hadjiyannakos, Dimitrios, Arvanitis, Dimitrios, Panagiotopoulos, Konstantinos, Vlassopoulos, Dimosthenis, Kaesler, Nadine, Schettgen, Thomas, Magdeleyns, Elke, Brandenburg, Vincent, Vermeer, Cees, Floege, J, Kr, Thilo, Randone, Olga, Ferraresi, Martina, Aroasio, Emiliano, Depascale, Agostino, Scognamiglio, Stefania, Consiglio, Valentina, Piccoli, Giorgina Barbara, Jensen, Line Vedel, Lizakowski, Slawomir, Rutkowski, Przemyslaw, Tylicki, Leszek, Renke, Marcin, Sulikowska, Beata, Donderski, Rafal, Bednarski, Rafal, Heleniak, Zbigniew, Przybylska, Milena, Manitius, Jacek, Rutkowski, Boleslaw, Bobrova, Larisa, Kozlovskaya, Natalia, Kanayama, Kyoko, Hasegawa, Midori, Kitagawa, Fumihiko, Ishii, Jyunichi, Yuzawa, Yukio, Tanaka, Kentaro, Sakai, Ken, Hara, Shigeko, Suzuki, Yasunori, Tanaka, Yoshihide, Aikawa, Atsushi, Hinoshita, Fumihiko, Hamano, Naoto, Sasaki, Emi, Kato, Asami, Katsuki, Takashi, Katsuma, Ai, Imai, Eri, Shibata, Maki, Tada, Manami, Shimbo, Takuro, Kikuchi, Yoshimi, Oka, Shinichi, Muramatsu, Takashi, Yanagisawa, Naoki, Fukutake, Katsuyuki, Yamamoto, Yasuyuki, Ajisawa, Atsushi, Tsuchiya, Ken, Nitta, Kosaku, Ando, Minoru, Liang, Xianhui, Wang, Pei, Liu, Zhangsuo, Zhao, Zhanzheng, Luyckx, Valerie, Bowker, Samantha, Miekle, Alison, Toth, Ellen, Heguilen, Ricardo, Malvar, Ana, Hermes, Ricardo, Cohen, Lilian, Muguerza, Graciela, Lococo, Bruno, Bernasconi, Amelia, Loboda, Olena, Dudar, Iryna, Krot, Viktor, Alekseeva, Viktoria, Ichinose, Mayuri, Sasagawa, Naru, Toyama, Katstuhide, Saito, Akira, Kayamori, Yuzo, Kang, Dongchon, Kim, Hyun Woo, Yoshioka, Kosuke, Hara, Masaki, Ohashi, Kazuteru, Maksudova, Adelya, Khalfina, Tamila, Cuoghi, Aurora, Bellei, Elisa, Caiazzo, Marialuisa, Bergamini, Stefania, Palladino, Giuseppe, Monari, Emanuela, Tomasi, Aldo, Loiacono, Elisa, Camilla, Roberta, Dapr, Valentina, Morando, Laura, Gallo, Rachele, Peruzzi, Licia, Conrieri, Margherita, Bianciotto, Manuela, Bosetti, Francesca M., Coppo, Rosannna, DI Lullo, Luca, Floccari, Fulvio, Rivera, Rodolfo, Granata, Antonio, Faiola, Rossella, Feliziani, Cherubino, Villani, Annalisa, Malaguti, Moreno, Santoboni, Alberto, Kyriaki, Kollia, Droulias, John, Bogdanova, Marina, Rameev, Vilen Vilevich, Simonyan, Armine Hachaturovna, Kozlovskaya, Lidia Vladimirovna, Altiparmak, Mehmet Riza, Trabulus, Sinan, Akalin, Nilg, Yalin, Ayse Serap, Esenkaya, Asim, Yalin, Serkan Feyyaz, Serdengeæ©, Kamil, Arita, Danielle, Cunha, Tatiana, Perez, Juliana, Sakata, Maí, Arita, Lilian, Nogueira, Marie, Jara, Zaira, Souza, Nᣩa, Casarini, Dulce, Metzger, Marie, Vallet, Marion, Vrtovsnik, Fran殩s, Karras, Alexandre, Froissart, Marc, Stengel, Bè©dicte, Houillier, Pascal, Paul, Katharina, Kretzschmar, Daniel, Yilmaz, Atilla, Bã±hlein, Barbara, Titze, Stephanie, Figulla, Hans-Reiner, Wolf, Gunter, Busch, Martin, Korotchaeva, Yulia, Gordovskaya, Nadezda, Kozlovskaya, Lidia, Ng, Khai Ping, Sharma, Praveen, Stringer, Stephanie, Jesky, Mark, Dutton, Mary, Ferro, Charles, Cockwell, Paul, Moon, Sung Jin, Lee, Sang Cheol, Yoon, Soo Young, Lee, Jung Eun, Han, Seung Jin, Anna, Bertram, Kirsch, Torsten, Svjetlana, Lovric, Joon-Keun, Park, Jan, Becker, Johanna, Kegel, Haller, Hermann, Haubitz, Marion, Smirnov, Alexey, Kayukov, Ivan, Rafrafi, Nowel, Degtereva, Olga, Dobronravov, Vladimir, Koch, Michael, Stefan, Heidenreich, Dika, Givka, Antoine, Marie-Hone, Husson, Cole, Kos, Jelena, Milic, Maja, Fucek, Mirjana, Cvoriocec, Dubravka, Bourgeade, Marie-Fran殩se, Nortier, Joêe L., Jelakovic, Bojan, Nawal, EL Hafid, Naoufal, Mtioui, Nabila, Mifdal, Fadwa, EL Mountahi, Salma, EL Khyat, Nisrine, Bennani, Mohamed, Zamd, Guislaine, Medkouri, Mohamed Gharbi, Benghanem, Benyounes, Ramdani, Sotila, Gianina Gabriela, Sorin, Rugina, Irina Magdalena, Dumitru, Roxana, Cernat, Claudia, Rugina, Correa Barcellos, Franklin, Hallal, Pedro Hallal, Bohlke, Maristela, Boscolo Del Vechio, Fabricio, Reges, Annelise, Santos, Ina, Mielke, Grè¦re, Fortes, Milena, Antunez, Bruno, Laganovic, Mario, Vukovic Lela, Ivana, Karanovic, Sandra, Seric, Jadranka, Premuic, Vedran, Fitrek, Margareta, Fodor, Ljiljana, Meljkovic Vrkic, Tajana, Bansal, Vinod, Hoppensteadt, Debra, Fareed, Jawed

مصطلحات موضوعية: Abstracts

الوصف: Introduction and Aims: Advanced Chronic Kidney Disease (CKD) is gaining increasing medical and economical importance. However there is not enough reliable information about disease course, treatmentvariation, and the impact of treatments under routine clinical conditions on patient survival, quality of life, and costs. This paper demonstrates the first results of a nationwide electronicregistry, based on nephrology clinic data, for the prospective observation of CKD in Germany Methods: A large network of nephrologist practices across Germany (FNDN, Forschungsnetzwerk Verband Deutsche Nierenzentren ) is participating in the project. In each participating center, routinely obtained clinical data for non-dialysis dependent CKD patients are documented electronically including age, gender, cause of CKD, comorbidities, laboratory values, hospitalisations, blood pressure, and medications. Data are collected quarterly by a software called QuaNT (Qualitäsicherung Nephrologie und Transplantation). Results: Cross-sectional data are provided from 59 participating nephrology clinics and 6,187 patients with CKD Stage 3-5 in the second quarter of 2011. The mean age ± standard deviation (SD) was 72 ± 12 years. The distribution of CKD Stages 3, 4, and 5 (Non-dialysis) was 60, 33, and 8%, respectively. Diabetic nephropathy was diagnosed in 26% of patients; the major underlying renal disease was hypertension/vascular nephropathy with 47%. Renin- angiotensin-system (RAS) inhibitors were prescribed in 78% of all patients. Vitamin D prescription (any) was observed in 43%, phosphate binders in 5%, iron (oral or IV) in 19%, erythropoietin-stimulating agents (ESA) in 15%, and aldosterone antagonists (spironolactone) in 8% of patients. Conclusions: This nationwide registry is a new initiative that provides a nationwide electronic data base to prospectively follow clinical care and outcomes among CKD patients. The number of participating patients and practices is expected to increase considerably. Variations in patient care, as typically ...

وصف الملف: text/html

العلاقة: http://ndt.oxfordjournals.org/cgi/content/short/27/suppl_2/ii96Test; http://dx.doi.org/10.1093/ndt/gfs215Test

الإتاحة: https://doi.org/10.1093/ndt/gfs215Test
http://ndt.oxfordjournals.org/cgi/content/short/27/suppl_2/ii96Test

المؤلفون: Agnes, Haris, Kalman, Polner, Jozsef, Aranyi, Henrik, Braunitzer, Mucsi, Istvan, Kamata, Kouju, Sano, Takashi, Naito, Shokichi, Okamoto, Tomoko, Okina, Chikako, Kamata, Mariko, Murano, Junya, Kobayashi, Kei, Uchida, Mamiko, Aoyama, Togo, Takeuchi, Yasuo, Nagaba, Yasushi, Sakamoto, Hisato, Torino, Claudia, Panuccio, Vincenzo, Clementi, Anna, Garozzo, Maurizio, Bonanno, Graziella, Boito, Rosalia, Natale, Giuseppe, Cicchetti, Teresa, Chippari, Antonio, Logozzo, Domenico, Alati, Giovanni, Cassani, Simonetta, Sellaro, Arcangelo, D'arrigo, Graziella, Tripepi, Giovanni, Roberta, Aliotta, Postorino, Maurizio, Mallamaci, Francesca, Zoccali, Carmine, Buonanno, Elisa, Brancaccio, Stefania, Fimiani, Vanessa, Napolitano, Paola, Spadola, Rosanna, Morrone, Luigi, DI Iorio, Biagio, Russo, Domenico, Betriu, Angels, Martinez-Alonso, Montserrat, Vidal, Teresa, Valdivielso, Jose, Fernandez, Elvira, Bernadette, Faller, Jean-Baptiste, Beuscart, Frimat, Luc, Madala, N.D., Thusi, G.P., Sibisi, N., Mazibuko, B.G., Assounga, A.G.H., Tsai, Ni-Chin, Wang, Hsiao-Han, Chen, Yun-Chen, Hung, Chi-Chih, Hwang, Shang-Jyh, Chen, Hung-Chen, Branco, Patricia, Adragao, Teresa, Birne, Rita, Martins, Ana Rita, Vizinho, Ricardo, Gaspar, Augusta, Grilo, Maria José, Barata, Jose Diogo, Bonhorst, Daniel, Adragão, Pedro, Kim, Jae Seok, Yang, Jae Won, Kim, Min Keun, Choi, Seung Ok, Han, Byoung Geun, Nathalie, Neirynck, Sunny, Eloot, Glorieux, Griet, Daniela, Barreto, Fellype, Barreto, Sophie, Liabeuf, Horst D, Lemke, Ziad, Massy, Raymond, Vanholder, Yanai, Mitsuru, Okada, Kazuyoshi, Takeuchi, Kazuhisa, Nitta, Kosaku, Takahashi, Susumu, Morena, Marion, Jaussent, Isabelle, Halkovich, Aurore, Dupuy, Anne-Marie, Bargnoux, Anne-Sophie, Chenine, Leila, Leray-Moragues, Hélène, Klouche, Kada, Vernhet, Hélène, Canaud, Bernard, Cristol, Jean-Paul, Shutov, Alexander, Serov, Valery, Kuznetsova, Julia, Menzorov, Maxim, Serova, Diana, Petrescu, Ligia, Zugravu, Adrian, Capusa, Cristina, Stancu, Simona, Cinca, Simona, Anghel, Cristina, Timofte, Delia, Medrihan, Lacramioara, Ionescu, Dorin, Mircescu, Gabriel, Hsu, Ta-Wei, Kuo, Ko-Lin, Hung, Szu-Chun, Tarng, Der-Cherng, Lee, Soobong, Kim, Ilyoung, Lee, Dongwon, Rhee, Harin, Song, Sangheon, Seong, Eunyoung, Kwak, Ihmsoo, Holzmann, Martin, Gardell, Carl, Jeppsson, Anders, Sartipy, Ulrik, Solak, Yalcin, Yilmaz, Mahmut Ilker, Caglar, Kayser, Saglam, Mutlu, Yaman, Halil, Sonmez, Alper, Unal, Hilmi Umut, Gok, Mahmut, Gaipov, Abduzhappar, Kayrak, Mehmet, Eyileten, Tayfun, Turk, Suleyman, Vural, Abdulgaffar, DI Lullo, Luca, Floccari, Fulvio, Rivera, Rodolfo, Granata, Antonio, D'amelio, Alessandro, Logias, Franco, Otranto, Giovanni, Malaguti, Moreno, Santoboni, Alberto, Fiorini, Fulvio, Connor, Thomas, Oygar, Deren, Nitsch, Dorothea, Gale, Danniel, Steenkamp, Retha, Neild, Guy H., Maxwell, Patrick, Louise Høgsbro, Ida, Redal-Baigorri, Belén, Sautenet, Benedicte, Halimi, Jean Michel, Caille, Agnes, Goupille, Philippe, Giraudeau, Bruno, Oguz, Yusuf, Yenicesu, Mujdat, Cetinkaya, Hakki, Ishimoto, Yu, Ohki, Takamasa, Sugahara, Mai, Kanemitsu, Takafumi, Kobayashi, Masafumi, Uchida, Lisa, Kotera, Nagaaki, Tanaka, Shinji, Sugimoto, Tokuichiro, Mise, Naobumi, Miyazaki, Nagisa, Matsumoto, Jun, Murata, Ichijiro, Yoshida, Gakuro, Morishita, Kentaro, Ushikoshi, Hiroaki, Nishigaki, Kazuhiko, Ogura, Shinji, Minatoguchi, Shinya, Harvey, Rebecca, Ala, Azhar, Banerjee, Debasish, Farmer, Christopher, Irving, Jean, Hobbs, Helen, Wheeler, Toby, Klebe, Bernhard, Stevens, Paul, Selim, Gjulsen, Stojceva-Taneva, Olivera, Tozija, Liljana, Stojcev, Nikola, Gelev, Saso, Dzekova-Vidimliski, Pavlina, Pavleska, Svetlana, Sikole, Aleksandar, Qureshi, Abdul Rashid, Evans, Marie, Stendahl, Maria, Prütz, Karl Göran, Elinder, Carl Gustaf, Tamagaki, Keiichi, Kado, Hiroshi, Nakata, Mayumi, Kitani, Takashi, Ota, Noriyoshi, Ishida, Ryo, Matsuoka, Eiko, Shiotsu, Yayoi, Ishida, Mami, Mori, Yasukiyo, Christelle, Maurice, Rognant, Nicolas, Evelyne, Decullier, Sophie, Fave, Laurent, Juillard, Maurice, Laville, Silverwood, Richard, Pierce, Mary, Kuh, Diana, Savage, Caroline, Ferro, Charles, Moniek, De Goeij, De Goeij, Moniek, Nynke, Halbesma, Gurbey, Ocak, Joris, Rotmans, Friedo, Dekker, Clayton, Philip, Grace, Blair, Cass, Alan, Mcdonald, Stephen, Lorenzo, Victor, Martin Conde, Marisa, Dusso, Adriana, Valdivielso, Jose M, Roggeri, Daniela Paola, Cannella, Giuseppe, Cozzolino, Mario, Mazzaferro, Sandro, Messa, Piergiorgio, Brancaccio, Diego, De Souza Faria, Ruiter, Fernandes, Natalia, Lovisi, Julio, Moura Marta, Murilo, Reboredo, Maycon, Do Vale Pinheiro, Bruno, Bastos, Marcus, Hundt, Felix, Pabst, Stefan, Hammerstingl, Christoph, Gerhardt, Thomas, Skowasch, Dirk, Woitas, Rainer, Lopes, Antonio Alberto, Silva, Luciana Ferreira, Matos, Cácia Mendes, Martins, Márcia Silva, Silva, Fernanda Albuquerque, Lopes, Gildete Barreto, Pizzarelli, Francesco, Dattolo, Pietro, Michelassi, Stefano, Rossi, Cristina, Bandinelli, Stefania, Mieth, Maren, Mass, Renke, Ferrucci, Luigi, Parisi, Silvia, Arduino, Silvana, Attini, Rossella, Fassio, Federica, Biolcati, Marilisa, Pagano, Arianna, Bossotti, Carlotta, Ferraresi, Martina, Gaglioti, Piero, Todros, Tullia, Piccoli, Giorgina Barbara, Salgado, Teresa M., Arguello, Blanca, Benrimoj, Shalom I., Fernandez-Llimos, Fernando, Bailey, Pippa, Tomson, Charlie, Ben-Shlomo, Yoav, Santoro, Antonio, Rucci, Paola, Mandreoli, Marcora, Caruso, Francesco, Corradini, Mattia, Flachi, Marta, Gibertoni, Dino, Rigotti, Angelo, Russo, Giorgia, Fantini, Mariapia, Mahapatra, Himansu Sekhar, Choudhury, Shamsunder, Buxi, Gurdeep, Sharma, Neera, Gupta, Yadunanda, Sekhar, Venkentsan, Yanagisawa, Naoki, Ando, Minoru, Ajisawa, Atsushi, Tsuchiya, Ken, Janusz, Ostrowski, Mikolaj, Majkowicz, Jacek, Manitius, Boleslaw, Rutkowski, Prakash, Suma, Coffin, Rick, Schold, Jesse, Einstadter, Douglas, Stark, Susan, Rodgers, Darlene, Howard, Matthew, Sehgal, Ashwini, Palmer, Suetonia, Tong, Allison, Manns, Braden, Craig, Jonathan, Ruospo, Marinella, Gargano, Letizia, Strippoli, Giovanni, Vecchio, Mariacristina, Petruzzi, Massimo, De Benedictis, M, Pellegrini, Fabio, Ohno, Yoshiteru, Ishimura, Eiji, Naganuma, Toshihide, Kondo, Kyoko, Fukushima, Wakaba, Mui, Kayo, Inaba, Masaaki, Hirota, Yoshio, Sun, Xuefeng, Jiang, Shimin, Gu, Hongxia, Chen, Yunshuang, XI, Chunsheng, Qiao, XI, Chen, Xiangmei, Daher, Elizabeth, Junior, Geraldo Silva, Jacinto, Camilla N., Pimentel, Rodrigo S., Aguiar, Graziela B.R., Lima, Caroline B., Borges, Renata C., Mota, Livia P.C., Melo, João Victor L., Melo, Saulo A., Canamary, Vanessa T., Alves, Marilia, Araújo, Sônia M.H.A., Huang, Yen Kai, Rogacev, Kyrill, Cremers, Bodo, Zawada, Adam, Seiler, Sarah, Binder, Nadine, Ege, Philipp, Große-Dunker, Gunnar, Heisel, Isabel, Hornof, Florian, Jeken, Jana, Rebling, Niko, Ulrich, Christof, Scheller, Bruno, Böhm, Michael, Fliser, Danilo, Heine, Gunnar Henrik, Robinson, Bm, Wang, Mia, Bieber, Brian, Fluck, Richard, Kerr, Peter G., Wikström, Björn, Krishnan, Mahesh, Nissenson, Allen, Pisoni, Ronald L., Mykleset, Solveig, Østhus, Tone Brit, Waldum, Bård, Os, Ingrid, Buttigieg, Jesmar, Cassar, Andrew, Farrugia Agius, Joseph, Hara, Masaki, Yamato, Masaya, Yasuda, Keiko, Sasaki, Koichi

مصطلحات موضوعية: Abstracts

الوصف: Introduction and Aims: The Birmingham Vasculitis Activity Score (BVAS) correlates closely with disease activity in patients with ANCA associated vasculitis, however, conflicting results have been reported about its association with mortality. In this retrospective cohort study we assessed if BVAS at the time of diagnosis predicts mortality in a group of consecutive patients with ANCA associated vasculitis treated at our center between January 1, 1998 and December 1, 2011. Methods: Ninety seven patients with ANCA associated vasculitis were treated at our center during the study period. Nine patients were lost to follow-up and one patient died within the first month, therefore they were excluded from subsequent analysis. Laboratory results and follow-up data were extracted form the medical records. Multivariable Cox proportional regression analysis was used to assess independent association between predictor variables and all cause mortality. Results: Data from eighty seven patients (35 males and 52 females, age 60 ± 13 years) were analyzed. Eighty four patients had an initial serum creatinine above the normal range, 47 had pulmonary involvement. The mean (± SD) BVAS score was 22 ± 6. The median (interquartile range) follow up was 669 (2078) days. Sixteen patients died within 3 months of diagnosis (“early mortality”) and 29 after the 90th day of follow-up (“late mortality”). In a multivariable Cox regression model the baseline BVAS score independently predicted all cause mortality (Hazard ratio [HR] 1.087; 95% confidence interval [CI] 1.017-1.163) after adjusting for age, gender, serum albumin, CRP and serum creatinine. Patients with a baseline BVAS score above the median (21) had a two-fold increase in the hazard of death (HR 2.16, 95% CI 1.059-4.406) in a similarly adjusted model. Early deaths were predicted only by age at diagnosis and CRP. Conclusions: The Birmingham Vasculitis Activity Score is a good predictor of mortality in patients with ANCA associated vasculitis, who predominantly have renal and ...

وصف الملف: text/html

العلاقة: http://ndt.oxfordjournals.org/cgi/content/short/27/suppl_2/ii378Test; http://dx.doi.org/10.1093/ndt/gfs236Test

الإتاحة: https://doi.org/10.1093/ndt/gfs236Test
http://ndt.oxfordjournals.org/cgi/content/short/27/suppl_2/ii378Test

المؤلفون: Kawasaki, Masanori, Sano, Keiji, Okubo, Munenori, Yokoyama, Haruko, Ito, Yoko, Murata, Ichijiro, Tsuchiya, Kunihiko, Minatoguchi, Shinya, Zhou, Xiangrong, Fujita, Hiroshi, Fujiwara, Hisayoshi

المساهمون: Ministry of Education, Culture, Sports, Science and Technology

المصدر: Journal of the American College of Cardiology ; volume 45, issue 12, page 1946-1953 ; ISSN 0735-1097

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine

الإتاحة: https://doi.org/10.1016/j.jacc.2004.09.081Test
https://api.elsevier.com/content/article/PII:S0735109705007461?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0735109705007461?httpAccept=text/plainTest

المؤلفون: Matsumoto-Miyazaki, Jun, Ushikoshi, Hiroaki, Suzuki, Kodai, Miyazaki, Nagisa, Nawa, Takahide, Okada, Hideshi, Yoshida, Shozo, Murata, Ichijiro, Ogura, Shinji, Minatoguchi, Shinya

المصدر: The Journal of Alternative and Complementary Medicine ; volume 24, issue 11, page 1076-1084 ; ISSN 1075-5535 1557-7708

الإتاحة: https://doi.org/10.1089/acm.2017.0365Test

المؤلفون: Matsumoto-Miyazaki, Jun, Miyazaki, Nagisa, Murata, Ichijiro, Yoshida, Gakuro, Ushikoshi, Hiroaki, Ogura, Shinji, Minatoguchi, Shinya

المصدر: The Journal of Alternative and Complementary Medicine ; volume 22, issue 4, page 306-314 ; ISSN 1075-5535 1557-7708

الإتاحة: https://doi.org/10.1089/acm.2015.0276Test

المؤلفون: Matsumoto-Miyazaki, Jun, Miyazaki, Nagisa, Ushikoshi, Hiroaki, Nawa, Takahide, Yoshida, Gakuro, Murata, Ichijiro, Ogura, Shinji, Minatoguchi, Shinya

المصدر: The Journal of Alternative and Complementary Medicine ; volume 20, issue 9, page 693-697 ; ISSN 1075-5535 1557-7708

مصطلحات موضوعية: Complementary and alternative medicine

الإتاحة: https://doi.org/10.1089/acm.2014.0154Test