المؤلفون: Mukherjee Sumana, Bandyopadhyay Gautam, Bhattacharya Aparna, Ghosh Ritu, Barui Gopinath, Karmakar Rupam

المصدر: Journal of Cytology, Vol 27, Iss 1, Pp 8-11 (2010)

مصطلحات موضوعية: Bronchogenic carcinoma, computed tomography, fine needle aspiration cytology, Cytology, QH573-671

الوصف: Background : Fine needle aspiration cytology (FNAC) may be diagnostic in candidates with indeterminate solitary pulmonary nodules (SPNs) suspicious of bronchogenic carcinoma. Aims : The study was performed to evaluate the usefulness of computed tomography (CT)-guided FNAC in our centre. Materials and Methods : All the cases had a strong clinical suspicion of lung cancer, negative bronchoscopy, negative sputum cytology for malignant cells and acid fast bacilli. A thorough radiological evaluation was made to rule out primary malignancy elsewhere. Results : A total of 94 patients were studied in one year. May-Grόnwald-Giemsa stain was used for the smears. The cytological diagnosis was correlated with clinical-radiological follow-up and biopsy to arrive at a final diagnosis. The procedure had a high sensitivity and specificity. Chi-square test was used to calculate statistical significance. Tumor of more than three centimeter and immediate cytological assessment significantly increased the yield. Review of slides added two cases of malignancy that were missed initially. There were very few complications. Conclusions : CT-guided FNAC was an accurate and safe procedure for SPNs.

وصف الملف: electronic resource

العلاقة: http://www.jcytol.org/article.asp?issn=0970-9371;year=2010;volume=27;issue=1;spage=8;epage=11;aulastTest=Mukherjee; https://doaj.org/toc/0970-9371Test; https://doaj.org/toc/0974-5165Test

الوصول الحر: https://doaj.org/article/6c1c48d33c8b476ba64808e0d692a1afTest

المؤلفون: Mukherjee Sumana, Bandyopadhyay Gautam, Dutta Chanda, Bhattacharya Aparna, Karmakar Rupam, Barui Gopinath

المصدر: Indian Journal of Pathology and Microbiology, Vol 52, Iss 1, Pp 20-24 (2009)

مصطلحات موضوعية: Ulcer, cancer, mast cell density, Pathology, RB1-214, Microbiology, QR1-502

الوصف: Various studies have shown the role of mast cells in chronic inflammatory states and in tumor growth. The study is designed to have an idea of the relationship of mast cell density (MCD) to gastric ulcer and cancer, to verify whether mast cell accumulation occurred in the two conditions especially in Indian patients and thus postulate that therapeutic strategies against mast cell mediators could be useful in treatment. Also, we want to review literature and attempt to explain our findings. A total of 240 patients, who underwent their first endoscopy and biopsy for a span of 21/2 years were studied retrospectively. Out of these, 210 cases that were either gastric ulcers or cancer were chosen for this MCD study. Biopsies were sectioned and stained routinely. Toluidine blue stain and copper grid was used to calculate MCD. Student′s t-Test was used to calculate the statistical significance of MCD. MCD in benign ulcers was much higher than in control subjects. MCD in well-differentiated cancers showed MCD higher than control. Poorly-differentiated adenocarcinoma showed lower MCD than well-differentiated adenocarcinoma. It was concluded that the accumulation of mast cells in gastric ulcers is an inflammatory response. MCD is increased in well-differentiated gastric cancers, which may be a mast cell mediated immune response or mast cells may have a role in tumor angiogenesis and produce factors for tumor progression. Poorly-differentiated adenocarcinoma apparently lacks mast cell mediated anti-tumor response in some unexplained way.

وصف الملف: electronic resource

العلاقة: http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=1;spage=20;epage=24;aulastTest=Mukherjee; https://doaj.org/toc/0377-4929Test

الوصول الحر: https://doaj.org/article/c3ffc4e2af434d9095e40021aecf7593Test

المؤلفون: Mukherjee Sumana, Bandyopadhyay Gautam, Saha Sandeep, Choudhuri Manoj

المصدر: Journal of Cytology, Vol 27, Iss 3, Pp 104-105 (2010)

مصطلحات موضوعية: Fine needle aspiration cytology, glomus tumor, subungal., Cytology, QH573-671

الوصف: Glomus tumors are uncommon, with an estimated incidence of 1.6%. Cytological descriptions of this tumor are few. We report a 15-year-old boy presenting with a painful subungual swelling. Fine needle aspiration cytology showed uniform cells with homogeneous chromatin and scanty cytoplasm. Cytology was reported as "suggestive of glomus tumor". Histopathological examination confirmed the diagnosis. Careful cytomorphological examination supported by appropriate clinical history should suggest the diagnosis of glomus tumor and help in preoperative diagnosis.

وصف الملف: electronic resource

العلاقة: http://www.jcytol.org/article.asp?issn=0970-9371;year=2010;volume=27;issue=3;spage=104;epage=105;aulastTest=Mukherjee; https://doaj.org/toc/0970-9371Test; https://doaj.org/toc/0974-5165Test

الوصول الحر: https://doaj.org/article/33f640f0e389485cb5302da55785fc09Test

المؤلفون: Mukherjee Sumana, Sen Sharmila, Biswas Pranab, Choudhuri Manoj

المصدر: Indian Journal of Pathology and Microbiology, Vol 52, Iss 2, Pp 217-218 (2009)

مصطلحات موضوعية: Desmin, myogenin, ovary, rhabdomyosarcomatous, sarcoma, Pathology, RB1-214, Microbiology, QR1-502

الوصف: A 49-year-old patient presented with a right ovarian mass, which, on microscopy, showed to consist of haphazardly oriented large pleomorphic cells with abundant cytoplasm. Periodic acid Schiff stain was positive but negative with diastase digestion. Immunohistochemical staining with Desmin showed intense cytoplasmic positivity in almost all the cells. Cytokeratin, epithelial membrane antigen, smooth muscle actin, HMB-45, S-100 and neurone-specific enolase were negative. Immunohistochemical staining with Myogenin showed intense nuclear positivity. There was no other primary tumor on extensive search. A diagnosis of primary sarcoma of the ovary with rhabdomyosarcomatous differentiation was made. The incidence of similar tumors of the ovary are low and therefore little data are available on this uniformly lethal tumor. Thus, such cases need to be reported to pool experience so that the tumor can be diagnosed early.

وصف الملف: electronic resource

العلاقة: http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=2;spage=217;epage=218;aulastTest=Mukherjee; https://doaj.org/toc/0377-4929Test

الوصول الحر: https://doaj.org/article/0aedfa47b3a94567a41d7817831454a3Test

المؤلفون: Richardson Annely M, Taylor Philip R, Goldstein Alisa M, Hu Nan, Erickson Heidi S, Rodriguez-Canales Jaime, Yan Wusheng, Dawsey Sanford M, Roth Mark J, Mukherjee Sumana, Tangrea Michael A, Chuaqui Rodrigo F, Emmert-Buck Michael R

المصدر: Journal of Translational Medicine, Vol 8, Iss 1, p 91 (2010)

مصطلحات موضوعية: Medicine

الوصف: Abstract Background Esophageal squamous cell carcinomas (ESCC) are usually asymptomatic and go undetected until they are incurable. Cytological screening is one strategy to detect ESCC at an early stage and has shown promise in previous studies, although improvement in sensitivity and specificity are needed. Proteases modulate cancer progression by facilitating tumor invasion and metastasis. In the current study, matrix metalloproteinases (MMPs) were studied in a search for new early detection markers for ESCC. Methods Protein expression levels of MMPs were measured using zymography in 24 cases of paired normal esophagus and ESCC, and in the tumor-associated stroma and tumor epithelium in one sample after laser capture microdissection (LCM). MMP-3 and MMP-10 transcripts in both the epithelium and stroma in five cases were further analyzed by quantitative reverse transcriptase polymerase chain reaction (qRT-PCR). Results Gelatin zymography showed bands corresponding in size to MMP-2, MMP-3, MMP-9, and MMP-10 enzymes in each of the 24 cancer cases. MMP levels tended to be higher in tumors than paired normal tissue; however, only the 45 kDa band that corresponds to the activated form of MMP-3 and MMP-10 was strongly expressed in all 24 tumors with little or no expression in the paired normal foci. LCM-based analysis showed the 45 kDA band to be present in both the stromal and epithelial components of the tumor microenvironment, and that MMP-3 and MMP-10 mRNA levels were higher in tumors than paired normal tissues for each compartment. Conclusions Increased levels of MMPs occur in ESCC suggesting their up-regulation is important in esophageal tumorigenesis. The up-regulated gene products have the potential to serve as early detection markers in the clinic.

وصف الملف: electronic resource

العلاقة: http://www.translational-medicine.com/content/8/1/91Test; https://doaj.org/toc/1479-5876Test

الوصول الحر: https://doaj.org/article/72f31e9940134812ae032051c7671c58Test

المؤلفون: Beegadhur, Shayne, Finn, Joshua, Delves, John, Mukherjee, Sumana, Patadia, Dhrumil, McKevitt, James, Sharma, Ramansha, Tavender, Radael, Dixon, Thomas, Senouci, Amine, Wasim, Ali, Ivahnenko, Nadiya

المصدر: Journal of the British Interplanetary Society (JBIS) , 76 (12) pp. 424-432. (2023)

مصطلحات موضوعية: Titan, CubeSat, Radioisotope, Thermoelectric Generator, Orbital Decey, Outer Solar System

الوصف: In the past decade, CubeSats have emerged as a cost-effective solution for scientific missions beyond Earth’s orbit, though they have not yet gone further than orbiting Mars, as with NASA’s MarCO CubeSats. This paper discusses the technical challenges and solutions for designing CubeSats for Outer Solar System missions, specifically in the context of the proposed Astraeus Mission to Titan. These CubeSats, called the Mites, aim to measure heavy anions in Titan’s upper atmosphere and have undergone analysis to determine their optimal size and drag coefficient. A significant challenge addressed is the CubeSats’ power system, with solar panels being less effective at greater distances from the Sun. The paper proposes investigating Radioisotope Power Systems (RPS) as an alternative. However, there is the additional challenge of packaging the RPS in a sufficiently small form factor so that the upper atmospheric experiment can be completed. This must cover the greatest range of longitudes, latitudes, and ranges hence the orbital decay rate must be controlled to achieve this. The paper also explores the Mites’ long-duration exposure to space during transit and strategies to minimise cosmic radiation exposure. Whilst this is completed in the context of the Astraeus Mission, the data obtained can guide similar missions and aid others in overcoming the limitations of CubeSats so that they can be used more frequently for Outer Solar System science missions.

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/10192031/1/jbis-076-12-0424%20Beegadhur.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10192031Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/10192031/1/jbis-076-12-0424%20Beegadhur.pdfTest
https://discovery.ucl.ac.uk/id/eprint/10192031Test/

المؤلفون: Sutradhar, Sushanta, Mukherjee, Joydeep, Mitra, Sayantan, Mukherjee, Sumana, Mondal, Sonjoy, Barman, Chiranjib

المصدر: Journal of Radioanalytical & Nuclear Chemistry; Jun2024, Vol. 333 Issue 6, p3159-3171, 13p

مصطلحات موضوعية: RADON, IONIZATION chambers, GROUNDWATER sampling, AGE groups, LUNG cancer, GROUNDWATER, WATER consumption

مصطلحات جغرافية: RANCHI (India), JHARKHAND (India), INDIA

مستخلص: The present study deals with an overview of the distribution of radon (Rn-222) concentration in the groundwater and its associated annual effective doses in Ranchi district, Jharkhand, India. The samples were collected from deep tube-wells and the Rn-222 concentration was measured in the collected samples using an ionization chamber type radon monitor AlphaGUARD. The measured Rn-222 activities in few groundwater samples are found beyond 100 Bq/L. The total annual effective dose (AED) has been estimated for three different age groups (adults, children and infants); and the result shows that the total AED of 72.17% samples for infant, 93.04% samples for children and 99.13% samples for adults are above 0.1 mSv/y. Additionally, the excess life-time cancer risk and the lung cancer cases per year per million persons (LLC) due to the consumption of the Rn-222 rich water have been assessed for the local inhabitants in this region. [ABSTRACT FROM AUTHOR]

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المؤلفون: Mukherjee , Sumana

المصدر: AGPE THE ROYAL GONDWANA RESEARCH JOURNAL OF HISTORY, SCIENCE, ECONOMIC, POLITICAL AND SOCIAL SCIENCE; Vol. 3 No. 3 (2022): 2021-22 (Issue 3); 61-67 ; 2583-1348 ; 2582-8800

مصطلحات موضوعية: Women identity, Gender justice, Patriarchy, Emancipation, Literature, English

الوصف: This paper attempts to examine through Anees Jung’s work Night of the New Moon, those socio-cultural and religious practices which through interpretation or (mis)interpretation by the patriarchal Muslim community, have kept women at a subjugated position since time immemorial. It also attempts to look beyond the veiled faces of Muslim women, and to peep into their lives in order to bring to the forefront their stories of pain and struggle that they have silently been suffering from, due to their degraded status, lack of individuality and justice in their family and community in particular and society at large. This would be done by bringing forth their unheard voices through the narratives of the Muslim women that Anees Jung have recorded during her interviews with them, in various parts of India. Apart from this, the paper would also ponder over the struggle that Muslim women are fighting to regain their lost identity, position, rights and justice in society so that they can be uplifted and emancipated and their problems can be resolved for a better and more prosperous future of our country.

وصف الملف: application/pdf

العلاقة: https://agpegondwanajournal.co.in/index.php/agpe/article/view/105/106Test; https://agpegondwanajournal.co.in/index.php/agpe/article/view/105Test

الإتاحة: https://agpegondwanajournal.co.in/index.php/agpe/article/view/105Test

المؤلفون: Mukherjee, Sumana, Singh, R. K., Taneja, S.C., Vyas, A.K., Anand, Anish, Singh, R.N.

المصدر: Power Engineer Journal 21(1):20-28. 2019

المؤلفون: Ghorai, Shakuntala, Mukherjee, Sumana, Mukherjee, Soumya, Khowala, Suman

المصدر: Biotechnology and Bioprocess Engineering ; volume 28, issue 5, page 887-887 ; ISSN 1226-8372 1976-3816

مصطلحات موضوعية: Biomedical Engineering, Applied Microbiology and Biotechnology, Bioengineering, Biotechnology

الإتاحة: https://doi.org/10.1007/s12257-023-1236-4Test