المؤلفون: Wu W, Jordan S, Graf N, de Oliveira Pena J, Curram J, Allanore Y, Matucci-Cerinic M, Pope JE, Denton CP, Khanna D, Distler O, Guiducci S, Walker U, Jaeger V, Bannert B, Lapadula G, Becvarare R, Cutolo M, Valentini G, Siegert E, Rednic S, Montecucco C, Carreira PE, Novak S, Czirják L, Varju C, Chizzolini C, Allai D, Kucharz EJ, Cozzi F, Rozman B, Mallia C, Gabrielli A, Bancel DF, Airò P, Hesselstrand R, Martinovic D, Balbir-Gurman A, Braun-Moscovici Y, Hunzelmann N, Pellerito R, Mauriziano O, Caramaschi P, Black C, Damjanov N, Henes J, Santamaria VO, Heitmann S, Seidel M, Pereira Da Silva JA, Stamenkovic B, Selmi CF, Tikly M, Denisov LN, Müller-Ladner U, Engelhart M, Hachulla E, Riccieri V, Ionescu RM, Mihai C, Sunderkötter C, Kuhn A, Schett G, Distler J, Meroni P, Ingegnoli F, Mouthon L, Keyser F, Smith V, Cantatore FP, Corrado A, Ullman S, Iversen L, Pozzi MR, Eyerich K, Hein R, Knott E, Wiland P, Szmyrka-Kaczmarek M, Sokolik R, Morgiel E, Madej M, Alegre-Sancho JJ, Krummel-Lorenz B, Saar P, Aringer M, Günther C, Anne E, Westhovens R, Langhe E, Lenaerts J, Anic B, Baresic M, Mayer M, Üprus M, Otsa K, Radominski SC, Müller CS, Azevedo VF, Popa S, Stebbings S, Highton J, Mathieu A, Vacca A, Stamp L, Chapman P, O'Donnell J, Solanki K, Doube A, Veale D, O'Rourke M, Loyo E, Li M, Rosato E, Amoroso A, Gigante A, Oksel F, Yargucu F, Tanaseanu CM, Popescu M, Dumitrascu A, Tiglea I, Foti R, Visalli E, Benenati A, Amato G, Ancuta C, Chirieac R, Villiger P, Adler S, Dan D, de la Peña Lefebvre PG, Rubio SR, Exposito MV, Sibilia J, Chatelus E, Gottenberg JE, Chifflot H, Litinsky I, Venalis A, Saketkoo LA, Lasky JA, Kerzberg E, Montoya F, Cosentino V, Limonta M, Brucato AL, Lupi E, Spertini F, Ribi C, Buss G, Martin T, Guffroy A, Poindron V, Chung L, Schmeiser T, Zebryk P, Riso N, Riemekasten G, Rezus E, Puttini PS, Yavuz

المساهمون: Wu, W, Jordan, S, Graf, N, de Oliveira Pena, J, Curram, J, Allanore, Y, Matucci-Cerinic, M, Pope, Je, Denton, Cp, Khanna, D, Distler, O, Guiducci, S, Walker, U, Jaeger, V, Bannert, B, Lapadula, G, Becvarare, R, Cutolo, M, Valentini, G, Siegert, E, Rednic, S, Montecucco, C, Carreira, Pe, Novak, S, Czirják, L, Varju, C, Chizzolini, C, Allai, D, Kucharz, Ej, Cozzi, F, Rozman, B, Mallia, C, Gabrielli, A, Bancel, Df, Airò, P, Hesselstrand, R, Martinovic, D, Balbir-Gurman, A, Braun-Moscovici, Y, Hunzelmann, N, Pellerito, R, Mauriziano, O, Caramaschi, P, Black, C, Damjanov, N, Henes, J, Santamaria, Vo, Heitmann, S, Seidel, M, Pereira Da Silva, Ja, Stamenkovic, B, Selmi, Cf, Tikly, M, Denisov, Ln, Müller-Ladner, U, Engelhart, M, Hachulla, E, Riccieri, V, Ionescu, Rm, Mihai, C, Sunderkötter, C, Kuhn, A, Schett, G, Distler, J, Meroni, P, Ingegnoli, F, Mouthon, L, Keyser, F, Smith, V, Cantatore, Fp, Corrado, A, Ullman, S, Iversen, L, Pozzi, Mr, Eyerich, K, Hein, R, Knott, E, Wiland, P, Szmyrka-Kaczmarek, M, Sokolik, R, Morgiel, E, Madej, M, Alegre-Sancho, Jj, Krummel-Lorenz, B, Saar, P, Aringer, M, Günther, C, Anne, E, Westhovens, R, Langhe, E, Lenaerts, J, Anic, B, Baresic, M, Mayer, M, Üprus, M, Otsa, K, Radominski, Sc, Müller, C

وصف الملف: STAMPA

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/30852552; info:eu-repo/semantics/altIdentifier/wos/WOS:000471068200025; volume:78 (5); firstpage:648; lastpage:656; numberofpages:9; journal:ANNALS OF THE RHEUMATIC DISEASES; http://hdl.handle.net/11567/942245Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85062660144

الإتاحة: https://doi.org/10.1136/annrheumdis-2018-213455Test
http://hdl.handle.net/11567/942245Test

المؤلفون: Michael Hughes 1 2, Suiyuan Huang 3 4, Juan Jose Alegre-Sancho 5, Patricia E Carreira 6, Merete Engelhart 7, Eric Hachulla 8, Joerg Henes 9, Eduardo Kerzberg 10, Maria Rosa Pozzi 11, Gabriela Riemekasten 12, Vanessa Smith 13, Gabriella Szücs 14, Marie Vanthuyne 15, Elisabetta Zanatta 16, Oliver Distler 17, Armando G Gabrielli 18, Anna-Maria Hoffmann-Vold 19, Virginia D Steen 20, Dinesh Khanna 3 21, EUSTAR Airò P, Allanore A, Ananieva Lp, Anic B, Balbir-Gurman A, Becvar R, Benvenuti F, Cantatore F P, Chung L S, Cuomo G, Cutolo M, Czirják L, Damjanov N, de Vries-Bouwstra J, Del Galdo F, Distler J, Eyerich K, Farge D, Foti R, Gheorghiu A M, Giollo A, Heitmann S, Herrick A, Hesselstrand R, Hsu I M, Hunzelmann N, Iannone F, Iudici M, Ionescuc M R, Ingegnoli F, Jose J, Joven B E, Kerzberg E, Kucharz E J, Kuwana M, Langhe E D, Launay D, Lefebvre P, Litinsky I, García de la Peña Lefebvre P, González-Martín J J, Li M, Loyo E, Martin T, Matucci-Cerinic M, Maurer B, Moroncini G, Mouthon L, Müller Cs, Müller-Ladner U, Novak S, Pastor P, Pecher A-C, Pellerito R, Pozzi M R, Oksel F, Rednic S, Rezus E, Riccieri V, Rosato E, Saketkoo L A, Salvador M J, Schmeiser T, Selmi C F, Sibilia J, Siegert E, Solanki K, Sommerlatte S, Spertini F, Stamenkovic B, Stamp L, Tanaseanu C-M, Tikly M, Tineo C, Ullman S, Üprus M, Vanthuyne M, Veale D, Walker U, Wiland P, Yargucu F, Yavuz S

المساهمون: Michael Hughes, 1 2, Suiyuan Huang, 3 4, Juan Jose Alegre-Sancho, 5, Patricia, E Carreira 6, Merete Engelhart, 7, Eric Hachulla, 8, Joerg Henes, 9, Eduardo Kerzberg, 10, Maria Rosa Pozzi, 11, Gabriela Riemekasten, 12, Vanessa Smith, 13, Gabriella Szücs, 14, Marie Vanthuyne, 15, Elisabetta Zanatta, 16, Oliver Distler, 17, Armando, G Gabrielli 18, Anna-Maria Hoffmann-Vold, 19, Virginia, D Steen 20, Dinesh Khanna, 3 21, EUSTAR Airò, P, Allanore, A, Ananieva, Lp, Anic, B, Balbir-Gurman, A, Becvar, R, Benvenuti, F, Cantatore, F P, Chung, L S, Cuomo, G, Cutolo, M, Czirják, L, Damjanov, N, de Vries-Bouwstra, J, Del Galdo, F, Distler, J, Eyerich, K, Farge, D, Foti, R, Gheorghiu, A M, Giollo, A, Heitmann, S, Herrick, A, Hesselstrand, R, Hsu, I M, Hunzelmann, N, Iannone, F, Iudici, M, Ionescuc, M R, Ingegnoli, F, Jose, J, Joven, B E, Kerzberg, E, Kucharz, E J, Kuwana, M, Langhe, E D, Launay, D, Lefebvre, P, Litinsky, I, García de la Peña Lefebvre, P, González-Martín, J J, Li, M, Loyo, E, Martin, T, Matucci-Cerinic, M, Maurer, B, Moroncini, G, Mouthon, L, Müller, C, Müller-Ladner, U, Novak, S, Pastor, P, Pecher, A-C, Pellerito, R, Pozzi, M R, Oksel, F, Rednic, S, Rezus, E, Riccieri, V, Rosato, E, Saketkoo, L A, Salvador, M J, Schmeiser, T, Selmi, C F, Sibilia, J, Siegert, E, Solanki, K, Sommerlatte, S, Spertini, F, Stamenkovic, B, Stamp, L, Tanaseanu, C-M, Tikly, M, Tineo, C, Ullman, S, Üprus, M, Vanthuyne, M, Veale, D, Walker, U, Wiland, P, Yargucu, F

العلاقة: info:eu-repo/semantics/altIdentifier/wos/WOS:000834333400001; journal:RHEUMATOLOGY; http://hdl.handle.net/11591/476009Test

الإتاحة: https://doi.org/10.1093/rheumatology/keac363Test
http://hdl.handle.net/11591/476009Test

المؤلفون: Iudici M, Mongin D, Siegert E, Carreira PE, Distler J, Henes J, Zanatta E, Hachulla E, De Luca G, Cutolo M, Müller CS, Santiago T, Tandaipan JL, Bianchi BV, De Santis M, Hoffmann-Vold AM, Gabrielli A, Distler O, Courvoisier DS, EUSTAR collaborators.

المساهمون: Iudici, M, Mongin, D, Siegert, E, Carreira, Pe, Distler, J, Henes, J, Zanatta, E, Hachulla, E, De Luca, G, Cutolo, M, Müller, C, Santiago, T, Tandaipan, Jl, Bianchi, Bv, De Santis, M, Hoffmann-Vold, Am, Gabrielli, A, Distler, O, Courvoisier, D, Eustar, Collaborators.

وصف الملف: STAMPA

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36099040; info:eu-repo/semantics/altIdentifier/wos/WOS:000869178700001; volume:Sep 13:keac533; firstpage:1; lastpage:9; numberofpages:9; journal:RHEUMATOLOGY; https://hdl.handle.net/11567/1099307Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85152156677

الإتاحة: https://doi.org/10.1093/rheumatology/keac533Test
https://hdl.handle.net/11567/1099307Test

المؤلفون: Elhai, Muriel, Boubaya, Marouane, Distler, Oliver, Smith, Vanessa, Matucci-Cerinic, Marco, Alegre Sancho, Juan José, Truchetet, Marie-Elise, Braun-Moscovici, Yolanda, Iannone, Florenzo, Novikov, Pavel I, Lescoat, Alain, Siegert, Elise, Castellví, Ivan, Airó, Paolo, Vettori, Serena, De Langhe, Ellen, Hachulla, Eric, Erler, Anne, Ananieva, Lidia, Krusche, Martin, López-Longo, F J, Distler, Jörg H W, Hunzelmann, Nicolas, Hoffmann-Vold, Anna-Maria, Riccieri, Valeria, Hsu, Vivien M, Pozzi, Maria R, Ancuta, Codrina, Rosato, Edoardo, Mihai, Carina, Kuwana, Masataka, Saketkoo, Lesley Ann, Chizzolini, Carlo, Hesselstrand, Roger, Ullman, Susanne, Yavuz, Sule, Rednic, Simona, Caimmi, Cristian, Bloch-Queyrat, Coralie, Allanore, Yannick Guiducci S, Walker UA, Kyburz D, Lapadula G, Maurer B, Jordan S, Dobrota R, Becvar R, Sierakowsky S, Bielecka OK, Sulli A, Cutolo M, Cuomo G, Nicoara I, Kahan A, Vlachoyiannopoulos PG, Montecucco CM, Caporali R, Stork J, Inanc M, Carreira PE, Novak S, Czirják L, Varju C, Kucharz EJ, Kotulska A, Kopec-Medrek M, Widuchowska M, Cozzi F, Rozman B, Mallia C, Coleiro B, Gabrielli A, Farge D, Wu C, Marjanovic Z, Faivre H, Hij D, Dhamadi R, Wollheim F, Scheja A, Wuttge DM, Andréasson K, Martinovic D, Balbir-Gurman A, Trotta F, Monaco AL, Pellerito R, Mauriziano O, Caramaschi P, Morovic-Vergles J, Black C, Denton C, Damjanov N, Henes J, Santamaria VO, Heitmann S, KrasowskaMatthias D, Hasler P, Burkhardt H, Himsel A, Bajocchi G, Pereira Da Silva JA, Salvador MJ, Stamenkovic B, Stankovic A, Selmi CF, Santis M, Tikly M, Denisov LN, Müller-Ladner U, Frerix M, Tarner I, Scorza R, Puppo F, Engelhart M, Strauss G, Nielsen H, Damgaard K, Szücs G, Mendoza AZ, Puente C, Sifuentes Giraldo WA, Midtvedt Ø, Reiseter S, Garen T, Launay D, Valesini G, Ionescu RM, Groseanu L, Opris D, Cornateanu RS, Ionitescu R, Gherghe AM, Soare A, Gorga M, Bojinca M, Milicescu M, Sunderkötter C, Kuhn A, Sandorfi N, Schett G, Beyer C, Meroni P, Ingegnoli F, Mouthon L, Keyser F, Melsens K, Cantatore FP, Corrado A, Iversen L, Mühlen CAV, Bohn JM, Lonzetti LS, Eyerich K, Hein R, Knott E, Wiland P, Szmyrka-Kaczmarek M, Sokolik R, Morgiel E, Madej M, Houssiau FA, Krummel-Lorenz B, Saar P, Aringer M, Günther C, Westhovens R, Lenaerts J, Anic B, Baresic M, Mayer M, Üprus M, Otsa K, Granel B, Müller CS, Radominski SC, Azevedo VF, Jimenez S, Busquets J, Agachi S, Groppa L, Chiaburu L, Russu E, Popa S, Zenone T, Pileckyte M, Mathieu A, Vacca A, Sampaio-Barros PD, Yoshinari NH, Marangoni RG, Martin P, Fuocco L, Stebbings S, Highton J, Chapman P, O'Donnell J, Stamp L, Doube A, Solanki K, Veale D, O'Rourke M, Loyo E, Li M, Abdel Atty Mohamed WA, Amoroso A, Gigante A, Oksel F, Yargucu F, Tanaseanu CM, Popescu M, Dumitrascu A, Tiglea I, Foti R, Chirieac R, Furst D, Villiger P, Adler S, Laar JV, Kayser C, Fathi N, Hassanien M, de la Peña Lefebvre PG, Rubio SR, Exposito MV, Chatelus E, Sibilia J, Gottenberg JE, Chifflot H, Litinsky I, Emery P, Buch M, Galdo FD, Venalis A, Butrimiene I, Venalis P, Rugiene R, Karpec D, Lasky JA, Cosentino V, Kerzberg E, Montoya F, Bianchi W, Carneiro S, Maretti GB, Bianchi DV, Limonta M, Brucato AL, Lupi E, Rosner I, Rozenbaum M, Slobodin G, Boulman N, Rimar D, Couto M, Kahl S, Chen F, McCloskey D, Malveaux H, Spertini F, Ribi C, Buss G, Martin T, Guffroy A, Poindron V, Chotchaeva F, Mukhin NA, Moiseev S, Herrick A.

المساهمون: Elhai, Muriel, Boubaya, Marouane, Distler, Oliver, Smith, Vanessa, Matucci-Cerinic, Marco, Alegre Sancho, Juan José, Truchetet, Marie-Elise, Braun-Moscovici, Yolanda, Iannone, Florenzo, Novikov, Pavel I, Lescoat, Alain, Siegert, Elise, Castellví, Ivan, Airó, Paolo, Vettori, Serena, De Langhe, Ellen, Hachulla, Eric, Erler, Anne, Ananieva, Lidia, Krusche, Martin, López-Longo, F J, Distler, Jörg H W, Hunzelmann, Nicola, Hoffmann-Vold, Anna-Maria, Riccieri, Valeria, Hsu, Vivien M, Pozzi, Maria R, Ancuta, Codrina, Rosato, Edoardo, Mihai, Carina, Kuwana, Masataka, Saketkoo, Lesley Ann, Chizzolini, Carlo, Hesselstrand, Roger, Ullman, Susanne, Yavuz, Sule, Rednic, Simona, Caimmi, Cristian, Bloch-Queyrat, Coralie, Allanore, Yannick Guiducci, S, Walker, Ua, Kyburz, D, Lapadula, G, Maurer, B, Jordan, S, Dobrota, R, Becvar, R, Sierakowsky, S, Bielecka, Ok, Sulli, A, Cutolo, M, Cuomo, G, Nicoara, I, Kahan, A, Vlachoyiannopoulos, Pg, Montecucco, Cm, Caporali, R, Stork, J, Inanc, M, Carreira, Pe, Novak, S, Czirják, L, Varju, C, Kucharz, Ej, Kotulska, A, Kopec-Medrek, M, Widuchowska, M, Cozzi, F, Rozman, B, Mallia, C, Coleiro, B, Gabrielli, A, Farge, D, Wu, C, Marjanovic, Z, Faivre, H, Hij, D, Dhamadi, R, Wollheim, F, Scheja, A, Wuttge, Dm, Andréasson, K, Martinovic, D, Balbir-Gurman, A, Trotta, F, Monaco, Al, Pellerito, R, Mauriziano, O, Caramaschi, P, Morovic-Vergles, J, Black, C, Denton, C, Damjanov, N, Henes, J, Santamaria, Vo, Heitmann, S, Krasowskamatthias, D, Hasler, P, Burkhardt, H

مصطلحات موضوعية: lung fibrosi, rituximab, skin fibrosi, systemic sclerosis

الوصف: To assess the safety and efficacy of rituximab in systemic sclerosis (SSc) in clinical practice.

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/30967395; volume:78; issue:7; firstpage:979-987; journal:EARD; http://hdl.handle.net/11369/382855Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85064192589

الإتاحة: https://doi.org/10.1136/annrheumdis-2018-214816Test
http://hdl.handle.net/11369/382855Test

المؤلفون: Elhai M, Meune C, Boubaya M, Avouac J, Hachulla E, Balbir-Gurman A, Riemekasten G, Airò P, Joven B, Vettori S, Cozzi F, Ullman S, Czirják L, Tikly M, Müller-Ladner U, Caramaschi P, Distler O, Iannone F, Ananieva LP, Hesselstrand R, Becvar R, Gabrielli A, Damjanov N, Salvador MJ, Riccieri V, Mihai C, Szücs G, Walker UA, Hunzelmann N, Martinovic D, Smith V, Müller CS, Montecucco CM, Opris D, Ingegnoli F, Vlachoyiannopoulos PG, Stamenkovic B, Rosato E, Heitmann S, Distler JHW, Zenone T, Seidel M, Vacca A, Langhe E, Novak S, Cutolo M, Mouthon L, Henes J, Chizzolini C, Mühlen CAV, Solanki K, Rednic S, Stamp L, Anic B, Santamaria VO, De Santis M, Yavuz S, Sifuentes-Giraldo WA, Chatelus E, Stork J, Laar JV, Loyo E, García de la Peña Lefebvre P, Eyerich K, Cosentino V, Alegre-Sancho JJ, Kowal-Bielecka O, Rey G, Matucci-Cerinic M, Allanore Y, EUSTAR group.

المساهمون: Elhai, M, Meune, C, Boubaya, M, Avouac, J, Hachulla, E, Balbir-Gurman, A, Riemekasten, G, Airò, P, Joven, B, Vettori, S, Cozzi, F, Ullman, S, Czirják, L, Tikly, M, Müller-Ladner, U, Caramaschi, P, Distler, O, Iannone, F, Ananieva, Lp, Hesselstrand, R, Becvar, R, Gabrielli, A, Damjanov, N, Salvador, Mj, Riccieri, V, Mihai, C, Szücs, G, Walker, Ua, Hunzelmann, N, Martinovic, D, Smith, V, Müller, C, Montecucco, Cm, Opris, D, Ingegnoli, F, Vlachoyiannopoulos, Pg, Stamenkovic, B, Rosato, E, Heitmann, S, Distler, Jhw, Zenone, T, Seidel, M, Vacca, A, Langhe, E, Novak, S, Cutolo, M, Mouthon, L, Henes, J, Chizzolini, C, Mühlen, Cav, Solanki, K, Rednic, S, Stamp, L, Anic, B, Santamaria, Vo, De Santis, M, Yavuz, S, Sifuentes-Giraldo, Wa, Chatelus, E, Stork, J, Laar, Jv, Loyo, E, García de la Peña Lefebvre, P, Eyerich, K, Cosentino, V, Alegre-Sancho, Jj, Kowal-Bielecka, O, Rey, G, Matucci-Cerinic, M, Allanore, Y, Eustar, Group.

وصف الملف: STAMPA

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/28835464; info:eu-repo/semantics/altIdentifier/wos/WOS:000412506700023; volume:76(11); firstpage:1897; lastpage:1905; numberofpages:9; journal:ANNALS OF THE RHEUMATIC DISEASES; http://hdl.handle.net/11567/889376Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85030983267

الإتاحة: https://doi.org/10.1136/annrheumdis-2017-211448Test
http://hdl.handle.net/11567/889376Test

المؤلفون: Souza, EJR, Muller, CS, Horimoto, AMC, Rezende, RA, Guimarães, I, Mariz, HA, Dantas, AT, Da Costa, IP, Del-Rio, APT, Sekiyama, J, Kahwage, CB, Kayser, C

المصدر: Scandinavian Journal of Rheumatology ; volume 46, issue 4, page 288-295 ; ISSN 0300-9742 1502-7732

الإتاحة: https://doi.org/10.1080/03009742.2016.1233994Test

المؤلفون: Cintă Pinzaru, S.^1,2, Müller, Cs.¹, Tódor, I. S.¹, Glamuzina, B.², Chis, V.¹

المصدر: Journal of Raman Spectroscopy. Jun2016, Vol. 47 Issue 6, p636-642. 7p.

مصطلحات موضوعية: *RAMAN spectra, *DENSITY functional theory, *RAMAN spectroscopy, *TOXINS, *SEAFOOD poisoning

مستخلص: Commercially available diarrhetic shellfish poisoning (DSP) marine toxins are limited to micrograms samples invisible to the naked eye or in small amounts of micromole concentration solutions that are not suitable for normal Raman spectroscopy. As the Raman-derived techniques are increasingly employed in various detection schemes of harmful substances, Raman spectra of the target compounds are essential for molecular recognition, detection and sensing reasons. Using a new μ-RIM™ stainless steel hydrophobic substrate, we recorded near-infrared micro-Raman spectrum of okadaic acid (OA), a DSP marine biotoxin from 75 µg recrystallized toxin after drop coating deposition. Excitation with the 785-nm line allowed the recovery and assembling of the Raman spectrum over the 100-3200 cm−1 spectral range on several OA microparticles, while the 532-nm line excited the fluorescence emission that hampered the Raman signal. Density functional theory calculations were conducted on the isolated species both in gas phase and in ethanol solution to accurately assess and interpret the experimentally observed Raman bands. A good correlation between the experimental and theoretical Raman bands allowed for a reliable vibrational Raman assignment. Owing to the molecular geometry with intramolecular hydrogen bonds, the CC conjugated systems together with the methyl groups exhibited dominant OA Raman bands. Unlike domoic acid, an amnesic shellfish poisoning toxin whose carboxyl group showed the most intense Raman band, OA Raman characteristic band was not assigned to carboxyl group. Copyright © 2016 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

المؤلفون: Cintă Pinzaru, S.^1,2, Müller, Cs.¹, Tomšić, S.², Venter, M. M.³, Cozar, B. I.⁴, Glamuzina, B.²

المصدر: Journal of Raman Spectroscopy. Jul2015, Vol. 46 Issue 7, p597-604. 8p.

مصطلحات موضوعية: *CAROTENES, *SPECTRUM analysis, *RAMAN effect, *CYCLOHEXENE, *GALLIUM aluminum arsenide

مستخلص: While recording SERS spectra of pure β-carotene at sub-micromole concentrations for reference purpose, we discovered an unusual spectral response never reported before. In pre-resonance conditions with the 532-nm line, SERS of β-carotene with AgNPs exhibits among the strong υ(CC) mode at 1512 cm−1 unshifted from normal Raman spectrum, additional strong bands at 1649, 1575 and 1387 cm−1 as well as other medium bands not observed in the Raman spectrum of the crystalline powder. Such behavior is explained in terms of selection rules relaxation upon cyclohexene terminal rings of the β-carotene interaction with the NP surface. AFM images of the SERS system suggested dimers and trimers clustering of the nanoparticles with adsorbed β-carotene. In light of the new SERS feature the consequences in correct interpretation of the SERS imaging from complex biosystems containing carotenoids are discussed. Relative intensity ratio of the β-carotene band at 1512 cm−1 and water against concentration allowed a reliable SERS calibration curve for 50 to 500 nmol l−1 concentration range and provided quantitative SERS assessment of the carotenoid content in the sea urchin ( Paracentrotus lividus) gonads extracts. Copyright © 2015 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

المؤلفون: Gulia A, Saggini A, Wiesner T, Fink-Puches R, Argenyi Z, Ferrara G, Müller CS, Vale E, Cerroni L

المصدر: Journal of the American Academy of Dermatology; Nov2011, Vol. 65 Issue 5, p991-1000.e7, 1p