المؤلفون: Hino, Utaro, Tamura, Ryota, Yo, Masahiro, Kase, Yoshitaka, Tsuda, Noboru, Miyauchi, Tsubasa, Sogano, Junki, Karatsu, Kosuke, Miwa, Tomoru, Toda, Masahiro

المصدر: Frontiers in Oncology ; volume 13 ; ISSN 2234-943X

مصطلحات موضوعية: Cancer Research, Oncology

الوصف: Recently, there has been growing interest in the presence and function of meningeal lymphatic vessels, with no direct evidence linking these vessels to primary brain tumors. We report a unique case of recurrent ependymoma in the dura mater, showing histopathological signs of lymphatic proliferation at the tumor attachment site. The patient initially presented with a headache, and was diagnosed with ZFTA fusion-positive supratentorial ependymoma, central nervous system WHO Grade 3. Following multiple dura mater recurrences and surgery, the fifth procedure revealed numerous tumors contralateral to the original site, with genetic testing confirming ZFTA fusion positivity, indicating recurrent ependymoma. Immunohistochemical analysis showed D2-40 + lymphatic vessel proliferation around tumor attachment sites within the dura mater. Elevated expression of ZEB1 , which is an epithelial-to-mesenchymal transition factor, was also observed, implicating potential involvement in the unique pathophysiology. The present case suggests a new process of metastasis through meningeal lymphatic vessels, although we were unable to visually confirm tumor cell infiltration into the lymphatic vessels. This case is the first report suggesting ependymoma metastasis through dural lymphatic vessels, underlining the need for further case accumulation and study to understand the mechanisms of this phenomenon.

الإتاحة: https://doi.org/10.3389/fonc.2023.1340167Test

المؤلفون: Tezuka, Toshiki, Nukariya, Tomonori, Katsumata, Masahiro, Miyauchi, Tsubasa, Tokuyasu, Daiki, Azami, Shunpei, Izawa, Yoshikane, Nagoshi, Narihito, Fujiwara, Hirokazu, Mizutani, Katsuhiro, Akiyama, Takenori, Toda, Masahiro, Nakahara, Jin, Nishimoto, Yoshinori

المصدر: Journal of Stroke and Cerebrovascular Diseases ; volume 32, issue 7, page 107152 ; ISSN 1052-3057

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine, Neurology (clinical), Rehabilitation, Surgery

الإتاحة: https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107152Test
https://api.elsevier.com/content/article/PII:S1052305723001751?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1052305723001751?httpAccept=text/plainTest

المؤلفون: Mizutani, Katsuhiro¹ (AUTHOR), Miyauchi, Tsubasa¹ (AUTHOR), Yamada, Yoshitake² (AUTHOR) yamada@rad.med.keio.ac.jp, Yamada, Minoru² (AUTHOR), Yokoyama, Yoichi² (AUTHOR), Kosugi, Kenzo¹ (AUTHOR), Yoshida, Keisuke³ (AUTHOR), Akiyama, Takenori¹ (AUTHOR), Toda, Masahiro¹ (AUTHOR), Jinzaki, Masahiro² (AUTHOR)

المصدر: Neuroradiology. Jun2024, Vol. 66 Issue 6, p963-971. 9p.

مصطلحات موضوعية: *JUGULAR vein, *DIAGNOSTIC imaging, *RESEARCH funding, *DATA analysis, *CEREBRAL veins, *BLOOD vessels, *COMPUTED tomography, *RETROSPECTIVE studies, *DIGITAL subtraction angiography, *DESCRIPTIVE statistics, *VENOGRAPHY, *SUPINE position, *SITTING position, *STATISTICS, *POSTURE, *SKULL, *BODY movement, *DATA analysis software, *PATIENT positioning

مستخلص: Purpose: Few studies have investigated the influence of posture on the external jugular and diploic venous systems in the head and cranial region. In this study, we aimed to investigate the effects of posture on these systems using upright computed tomography (CT) scanning. Methods: This study retrospectively analysed an upright CT dataset from a previous prospective study. In each patient, the diameters of the vessels in three external jugular tributaries and four diploic veins were measured using CT digital subtraction venography in both supine and sitting positions. Results: Amongst the 20 cases in the original dataset, we eventually investigated 19 cases due to motion artifacts in 1 case. Compared with the supine position, most of the external jugular tributaries collapsed, and the average size significantly decreased in the sitting position (decreased by 22–49% on average). In contrast, most of the diploic veins, except the occipital diploic veins, tended to increase or remain unchanged (increased by 12–101% on average) in size in the sitting position compared with the supine position. However, the changes in the veins associated with this positional shift were not uniform; in approximately 5–30% of the cases, depending on each vein, an opposite trend was observed. Conclusion: Compared to the supine position, the contribution of external jugular tributaries to head venous drainage decreased in the sitting position, whilst most diploic veins maintained their contribution. These results could enhance our understanding of the physiology and pathophysiology of the head region in upright and sitting positions. [ABSTRACT FROM AUTHOR]

المؤلفون: 宮内, 翼, Miyauchi, Tsubasa

وصف الملف: application/pdf

الوصول الحر: https://ndlsearch.ndl.go.jp/books/R100000039-I12219186Test

Degree: 博士(工学) -- 鳥取大学

المؤلفون: Miyauchi, Tsubasa¹ (AUTHOR), Mizutani, Katsuhiro¹ (AUTHOR) katsu512@yahoo.co.jp, Akiyama, Takenori¹ (AUTHOR), Toda, Masahiro¹ (AUTHOR)

المصدر: Neuroradiology. Jan2024, Vol. 66 Issue 1, p55-62. 8p.

مصطلحات موضوعية: *VENOGRAPHY, *ELECTIVE surgery, *VEINS, *DIGITAL subtraction angiography, *NEUROSURGERY, *FORAMEN magnum, *SURGICAL arteriovenous shunts, *CRANIOVERTEBRAL junction, *COMPUTED tomography, *NEURORADIOLOGY, *INNERVATION

مستخلص: Purpose: Bridging veins (BVs) serve as a route of pial venous reflux, and its anatomy is essential to understand the pathophysiology of dural arteriovenous shunts (dAVSs) around the craniocervical junction (CCJ) (from the jugular foramen level to the atlantal level). However, the anatomical variations of the BVs and their proximal connections remained poorly elucidated. This study aimed to radiologically investigate the anatomy of the bridging veins around CCJ and discuss the clinical significance of these BVs in the dAVS. Methods: We investigated normal venous anatomy of the BVs from the jugular foramen level to the atlantal level using preoperative computed tomography digital subtraction venography in patients undergoing elective neurosurgery. BVs affected by the dAVSs in the same region were also evaluated. The three types of dAVS, craniocervical junction, anterior condylar, and proximal sigmoid sinus, were investigated. Results: We identified six BV groups: superolateral, anterolateral, lateral, posterior, inferolateral, and inferoposterior. The superolateral and inferolateral groups, connected with the proximal sigmoid sinus and suboccipital cavernous sinus, respectively, were the largest groups. Each group has a specific downstream venous connection. The association with dVASs was observed only in the inferolateral group, which was typically the sole venous drainage in most dAVSs at the CCJ. Conclusion: We reported detailed anatomy of BVs from the jugular level to the atlantal level, which enhanced our understanding of the pathophysiology of dAVSs in the corresponding region. [ABSTRACT FROM AUTHOR]

المؤلفون: Karatsu, Kosuke, Tamura, Ryota, Miyauchi, Tsubasa, Sogano, Junki, Hino, Utaro, Iwama, Takashi, Toda, Masahiro

المصدر: Medicina (1010660X); Aug2023, Vol. 59 Issue 8, p48, 9p

مصطلحات موضوعية: SKULL base, SKULL surgery, POSTOPERATIVE pain treatment, POSTERIOR cranial fossa, NEUROPATHY, POSTHERPETIC neuralgia, TRIGEMINAL nerve diseases, ANALGESIA

مستخلص: Background: Postoperative trigeminal neuropathy may be seen after surgery for middle and posterior cranial fossa lesions. Although neuropathic pain is a cause of reduced quality of life, global consensus on postoperative pain management is lacking. Mirogabalin besylate is a selective ligand for the α2δ subunit of voltage-gated calcium channels. Although mirogabalin has been used for patients with postherpetic neuralgia and painful diabetic peripheral neuropathy, few reports have assessed the effect on postsurgical neuropathy. In this report, we describe a clinical effectiveness of mirogabalin for trigeminal neuropathy after skull base surgery. Case description: Case 1: A 51-year-old female with right trigeminal schwannoma was operated on via the anterior transpetrosal approach. She had tingling and numb feelings in the right face postoperatively. Mirogabalin was orally administered after the operation. Her continuous facial numbness immediately improved. Case 2: A 55-year-old female with left middle fossa base meningioma extending into the infratemporal fossa was operated on via the infratemporal fossa approach. She had a tingling feeling in the left face postoperatively. Mirogabalin was orally administered for this symptom after the operation, which gradually improved. Conclusions: Mirogabalin may show significant pain relief for patients with trigeminal neuropathy after skull base surgery. Further studies using a larger number of patients are warranted to confirm these findings. [ABSTRACT FROM AUTHOR]

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المؤلفون: Miyauchi, Tsubasa, Mizutani, Katsuhiro, Akiyama, Takenori, Toda, Masahiro

المصدر: Neuroradiology ; volume 66, issue 1, page 55-62 ; ISSN 0028-3940 1432-1920

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine, Neurology (clinical), Radiology, Nuclear Medicine and imaging

الإتاحة: https://doi.org/10.1007/s00234-023-03232-8Test

المؤلفون: Miyauchi, Tsubasa, Yoshii, Masami, Oshima, Takeo, Tomotsune, Ken, Tomiyasu, Kazuhiro

المساهمون: no funding

المصدر: Neurocase ; volume 28, issue 5, page 432-438 ; ISSN 1355-4794 1465-3656

الإتاحة: https://doi.org/10.1080/13554794.2022.2145906Test

المؤلفون: Miyauchi, Tsubasa, Ganaha, Wataru, Nishiyama, Masashi, Iwai, Yoshio

المصدر: Lecture Notes in Computer Science ; Human-Computer Interaction. Interaction Techniques and Novel Applications ; page 44-55 ; ISSN 0302-9743 1611-3349 ; ISBN 9783030784645 9783030784652

الإتاحة: https://doi.org/10.1007/978-3-030-78465-2_4Test

المؤلفون: Miyauchi, Tsubasa, Nishiyama, Masashi, Iwai, Yoshio

المصدر: Lecture Notes in Computer Science ; Human-Computer Interaction. Design Practice in Contemporary Societies ; page 341-352 ; ISSN 0302-9743 1611-3349 ; ISBN 9783030226350 9783030226367

الإتاحة: https://doi.org/10.1007/978-3-030-22636-7_25Test