يعرض 1 - 10 نتائج من 18 نتيجة بحث عن '"Mendizabal, Y"', وقت الاستعلام: 1.64s تنقيح النتائج
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    دورية أكاديمية

    الوصف: Due to a higher capability in resolving white matter fiber crossings, Spherical Deconvolution (SD) methods have become very popular in brain fiber-tracking applications. However, while some of these estimation algorithms assume a central Gaussian distribution for the MRI noise, its real distribution is known to be non-Gaussian and to depend on many factors such as the number of coils and the methodology used to combine multichannel signals. Indeed, the two prevailing methods for multichannel signal combination lead to noise patterns better described by Rician and noncentral Chi distributions. Here we develop a Robust and Unbiased Model-BAsed Spherical Deconvolution (RUMBA-SD) technique intended to deal with realistic MRI noise. The algorithm relies on a maximum a posteriori formulation based on Rician and noncentral Chi likelihood models and includes a total variation (TV) spatial regularization term. By means of a synthetic phantom contaminated with noise mimicking patterns generated by data processing in multichannel scanners, the performance of RUMBA-SD is compared to that of other well-established SD methods (i.e., CSD and dRL-SD). The inclusion of proper likelihood models and TV regularization in RUMBA-SD leads to an increased ability to resolve fiber crossings with smaller inter-fiber angles and an increased robustness to noise. Finally, the proposed method is also validated in human brain data, producing the most stable fiber reconstructions in front of differing noise types and diffusion schemes based on a small number of gradient directions.

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    الوصف: Due to a higher capability in resolving white matter fiber crossings, Spherical Deconvolution (SD) methods have become very popular in brain fiber-tracking applications. However, while some of these estimation algorithms assume a central Gaussian distribution for the MRI noise, its real distribution is known to be non-Gaussian and to depend on many factors such as the number of coils and the methodology used to combine multichannel signals. Indeed, the two prevailing methods for multichannel signal combination lead to noise patterns better described by Rician and noncentral Chi distributions. Here we develop a Robust and Unbiased Model-BAsed Spherical Deconvolution (RUMBA-SD) technique intended to deal with realistic MRI noise. The algorithm relies on a maximum a posteriori formulation based on Rician and noncentral Chi likelihood models and includes a total variation (TV) spatial regularization term. By means of a synthetic phantom contaminated with noise mimicking patterns generated by data processing in multichannel scanners, the performance of RUMBA-SD is compared to that of other well-established SD methods (i.e., CSD and dRL-SD). The inclusion of proper likelihood models and TV regularization in RUMBA-SD leads to an increased ability to resolve fiber crossings with smaller inter-fiber angles and an increased robustness to noise. Finally, the proposed method is also validated in human brain data, producing the most stable fiber reconstructions in front of differing noise types and diffusion schemes based on a small number of gradient directions.

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    دورية أكاديمية
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    كتاب
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    كتاب
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    دورية أكاديمية
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    دورية أكاديمية
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    دورية أكاديمية
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    المؤلفون: Mendizabal y Oriza, David

    المساهمون: Flores Coto, Cesar Eduardo

    المصدر: Universidad Nacional Autónoma de México
    UNAM
    Repositorio de Tesis DGBSDI, Dirección General de Bibliotecas y Servicios Digitales de Información, UNAM

    مصطلحات موضوعية: Ciencias Biológicas, Químicas y de la Salud

    وصف الملف: application/pdf