المؤلفون: Novara, C., Martos-Méndez, M.J., Gómez-Jacinto, L., Hombrados-Mendieta, I., Varveri, L., Polizzi, C.

المساهمون: Universidad de Málaga

المصدر: International Journal of Intercultural Relations ; volume 92, page 101743 ; ISSN 0147-1767

مصطلحات موضوعية: Sociology and Political Science, Social Psychology, Business and International Management

الإتاحة: https://doi.org/10.1016/j.ijintrel.2022.101743Test
https://api.elsevier.com/content/article/PII:S0147176722001663?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0147176722001663?httpAccept=text/plainTest

المؤلفون: Hernantes-Colias, N. (Naia), Bermejo-Martins, E. (Elena), Overgard, K.I. (Kjell Ivar), Pumar-Mendez, M.J. (María Jesús), Lopez-Dicastillo, O. (Olga), Iriarte-Roteta, A. (Andrea), Antoñanzas-Baztan, E. (Elena), Mujika, A. (Agurtzane)

مصطلحات موضوعية: Capacity building, Health broker, Health in all policies, Health promotion, Intersectoral action, Local governments, Public health nursing, Social determinants of health

الوصف: Aim To design, implement and evaluate a nurse-led capacity building intervention (PromoGOB) for intersectoral action for health at local governments. Design The programme was based on theories of the policy process and organizational change and facilitated by a nurse developing a health broker role. A complex intervention perspective was adopted in carrying out the study. The intervention was evaluated using a mixed method embedded design. Methods Quantitative component relied on a specific questionnaire. This tool, designed and piloted ad hoc, measured the capacity in terms of knowledge, awareness, resources, skills, and commitment, both at sectoral and government levels. For the qualitative component, semi-structured interviews were conducted. These explored the perceived capacity and feasibility and acceptability issues. The programme was initiated at the end of October 2019, and it lasted a total of 5 weeks. Nineteen individuals representing various sectors at a local government in northern Spain participated in the study. The data analysis was concluded by the end of March 2020. Findings PromoGOB positively influenced participants' capacity for addressing health promotion. Awareness component, intersectoral work and the nurse as health broker were essential in the programme. The necessity of political participation was identified as an issue to be prioritized in future studies.

وصف الملف: application/pdf

العلاقة: https://hdl.handle.net/10171/63573Test

الإتاحة: https://hdl.handle.net/10171/63573Test

المؤلفون: Redruello-Requejo, M. (Marina), Samaniego-Vaesken, M.L. (María de Lourdes), Partearroyo, T. (Teresa), Rodriguez, P. (Paula), Soto-Méndez, M.J. (María José), Hernández-Ruiz, Á, (Ángela), Lara-Villoslada, F. (Federico), Leis, R. (Rosaura), Martínez-de-Victoria, E. (Emilio), Moreno-Villares, J.M. (José Manuel), Ortega, R.M. (Rosa María), Ruiz-López, M.D. (María Dolores), Gil, A. (Ángel), Varela-Moreiras, G. (Gregorio)

مصطلحات موضوعية: Materias Investigacion::Ciencias de la Salud::Pediatría, EsNuPI study, Pediatrics, Spanish children, Feeding behavior, Dietary habits, Nutrition assessment, Pediatric nutrition, Intrinsic sugar, Added sugar, Free sugars

الوصف: Currently, in Spain there are no studies assessing the intakes and sources of intrinsic and added sugars by both children consuming standard milks and children regularly consuming adapted milk formulas. Our goal was to evaluate current sugar intake levels (intrinsic and added) and their major dietary sources within the EsNuPI study participants by applying two 24-h dietary recalls that were completed by 1448 children (1 to <10 years) divided into two subsamples: One “Spanish Reference Sample” (SRS) of the general population (n = 707) and another sample which included children consuming adapted milks including follow-on milk, toddler’s or growing up milk and fortified and enriched milks, here called “Adapted Milk Consumers Sample” (AMS) (n = 741). Estimates of intrinsic and added sugar intakes from the Spanish EsNuPI population as well as the adherence to recommendations varied notably according to age segment, but no major differences between subsamples were found. Younger children (1 to <3 years) showed the highest added sugar contribution to total energy intake (TEI) (SRS: 12.5% for boys and 11.7% for girls; AMS: 12.2% for boys and 11.3% for girls) and the lowest adherence to recommendations set at <10% TEI (SRS: 27.4% for boys and 37.2% for girls; AMS: 31.3% for boys and 34.7% for girls). Adherence increased with age but remains inadequate, with approximately one in two children from the older age segment (6 to <10 years) exceeding the recommendations. Main food sources of intrinsic sugars for both subsamples were milk and dairy products, fruits, vegetables and cereals, while for added sugars, these were milk and dairy products (mainly yogurts), sugars and sweets (mainly sugary cocoa and nougat), bakery products (mainly cookies) and cereals (mainly bread and wheat flour). However, for the AMS, the groups milk and dairy products and cereals showed a significantly lower contribution to intrinsic sugar intake but a significantly higher contribution to that of added sugars. These results demonstrate ...

وصف الملف: application/pdf

العلاقة: https://hdl.handle.net/10171/68274Test

الإتاحة: https://hdl.handle.net/10171/68274Test

المؤلفون: Grande, Enrique, Alonso Gordoa, Teresa, Reig Torras, Oscar, Esteban, E., Castellano, D., Garcia Del Muro, Xavier, Mendez, M.J., García Donas, J., González Rodríguez, M., Arranz Arija, José Ángel, Lopez Criado, P., Molina Cerrillo, J., Mellado González, Begoña, Alvarez Fernandez, C., Velasco, G. de, Cuéllar Rivas, M.A., Rodríguez Alonso, R.M., Rodríguez Moreno, J.F., Suarez Rodriguez, C.

المصدر: Articles publicats en revistes (Ciències Clíniques)

مصطلحات موضوعية: Càncer de ronyó, Inhibidors enzimàtics, Renal cancer, Enzyme inhibitors

الوصف: Background: The INMUNOSUN trial had the objective of prospectively evaluating the efficacy and safety of sunitinib as a pure second-line treatment in patients with metastatic renal cell carcinoma (mRCC) who have progressed to first-line immune checkpoint inhibitor (ICI)-based therapies. Patients and methods: A multicenter, phase II, single-arm, open-label study was carried out in patients with a histologically confirmed diagnosis of mRCC with a clear-cell component who had progressed to a first-line regimen of ICI-based therapies. All patients received sunitinib 50 mg once daily orally for 4 weeks, followed by a 2-week rest period following package insert instructions. The primary outcome was the objective response rate. Results: Twenty-one assessable patients were included in the efficacy and safety analyses. Four patients [19.0%, 95% confidence interval (CI) 2.3% to 35.8%] showed an objective response (OR), and all of them had partial responses. Additionally, 14 (67%) patients showed a stable response, leading to clinical benefit in 18 patients (85.7%, 95% CI 70.7% to 100%). Among the four assessable patients who showed an OR, the median duration of the response was 7.1 months (interquartile range 4.2-12.0 months). The median progression-free survival (PFS) was 5.6 months (95% CI 3.1-8.0 months). The median overall survival (OS) was 23.5 months (95% CI 6.3-40.7 months). Patients who had better antitumor response to first-line ICI-based treatment showed a longer PFS and OS with sunitinib. The most frequent treatment-emergent adverse events were diarrhea (n = 11, 52%), dysgeusia (n = 8, 38%), palmar-plantar erythrodysesthesia (n = 8, 38%), and hypertension (n = 8, 38%). There was 1 patient who exhibited grade 5 pancytopenia, and 11 patients experienced grade 3 adverse events. Eight (38%) patients had serious adverse events, four of which were considered to be related to sunitinib. Conclusion: Although the INMUNOSUN trial did not reach the pre-specified endpoint, it demonstrated that sunitinib is active and can ...

وصف الملف: 9 p.; application/pdf

العلاقة: Reproducció del document publicat a: https://doi.org/10.1016/j.esmoop.2022.100463Test; ESMO Open, 2022, vol. 7, num. 2; https://doi.org/10.1016/j.esmoop.2022.100463Test; http://hdl.handle.net/2445/186251Test; 732592

الإتاحة: https://doi.org/10.1016/j.esmoop.2022.100463Test
http://hdl.handle.net/2445/186251Test

المؤلفون: Grande, E., Alonso-Gordoa, T., Reig, O., Esteban, E., Castellano, D., Garcia-del-Muro, X., Mendez, M.J., García-Donas, J., González Rodríguez, M., Arranz-Arija, J.A., Lopez-Criado, P., Molina-Cerrillo, J., Mellado, B., Alvarez-Fernandez, C., De Velasco, G., Cuéllar-Rivas, M.A., Rodríguez-Alonso, R.M., Rodríguez-Moreno, J.F., Suarez-Rodriguez, C.

المصدر: ESMO Open ; volume 7, issue 2, page 100463 ; ISSN 2059-7029

مصطلحات موضوعية: Cancer Research, Oncology

الإتاحة: https://doi.org/10.1016/j.esmoop.2022.100463Test
https://api.elsevier.com/content/article/PII:S2059702922000813?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2059702922000813?httpAccept=text/plainTest

المؤلفون: Madrigal, C. (Casandra), Soto-Méndez, M.J. (María José), Valero, T. (Teresa), Lara-Villoslada, F. (Federico), Leis, R. (Rosaura), Martínez-de-Victoria, E. (Emilio), Moreno-Villares, J.M. (José Manuel), Ortega, R.M. (Rosa María), Ruiz-López, M.D. (María Dolores), Varela-Moreiras, G. (Gregorio), Gil, A. (Ángel), Hernández-Ruiz, Á, (Ángela)

مصطلحات موضوعية: Materias Investigacion::Ciencias de la Salud::Nutrición y dietética, Dietary proteins, Proteins, Dietary animal protein, Dietary plant protein, Pediatric nutrition, Fortified milk, Food sources, Dairy products, Spanish children, EsNuPI study

الوصف: Diet in the first years of life is an important factor in growth and development. Dietary protein is a critical macronutrient that provides both essential and nonessential amino acids required for sustaining all body functions and procedures, providing the structural basis to maintain life and healthy development and growth in children. In this study, our aim was to describe the total protein intake, type and food sources of protein, the adequacy to the Population Reference Intake (PRI) for protein by the European Food Safety Authority (EFSA), and the Recommended Dietary Allowance (RDA) by the Institute of Medicine (IoM). Furthermore, we analyzed whether the consumption of dairy products (including regular milk, dairy products, or adapted milk formulas) is associated with nutrient adequacy and the contribution of protein to diet and whole dietary profile in the two cohorts of the EsNuPI (in English, Nutritional Study in the Spanish Pediatric Population) study; one cohort was representative of the Spanish population from one to <10 years old (n = 707) (Spanish reference cohort, SRS) who reported consuming all kinds of milk and one was a cohort of the same age who reported consuming adapted milk over the last year (including follow-on formula, growing up milk, toddler’s milk, and enriched and fortified milks) (n = 741) (adapted milk consumers cohort, AMS). The children of both cohorts had a high contribution from protein to total energy intake (16.79% SRS and 15.63% AMS) and a high total protein intake (60.89 g/day SRS and 53.43 g/day AMS). We observed that protein intake in Spanish children aged one to <10 years old was above the European and international recommendations, as well as the recommended percentages for energy intakes. The main protein sources were milk and dairy products (28% SRS and 29% AMS) and meat and meat products (27% SRS and 26% AMS), followed by cereals (16% SRS and 15% AMS), fish and shellfish (8% in both cohorts), eggs (5% SRS and 6% AMS), and legumes (4% in both cohorts). In our ...

وصف الملف: application/pdf

العلاقة: https://hdl.handle.net/10171/68251Test

الإتاحة: https://hdl.handle.net/10171/68251Test

المؤلفون: Belintxon, M. (Maider), Carvajal, A. (Ana), Pumar-Mendez, M.J. (María Jesús), Rayón-Valpuesta, P (Pedro), Raquel, Belintxon, U. (Unai), Dogra, N. (Nisha), Vidaurreta, M. (Marta), Bermejo-Martins, E. (Elena), Lopez-Dicastillo, O. (Olga)

مصطلحات موضوعية: Cultural competence, Cultural diversity, Cultural sensibility, Nursing student, Psychometric properties, Validation study

الوصف: Background: Cultural sensibility is an important concept linked to the achievement of cultural competence. Health professionals must first improve their cultural sensibility to become culturally competent and to be able to offer competent care to culturally diverse populations. Aim To develop and psychometrically test the Cultural Sensibility Scale for Nursing (CUSNUR), a cultural sensibility scale that can be used in nursing for the achievement of competencies needed to care for culturally diverse populations. Design and methods: The cross-sectional survey was conducted over two stages. The first stage involved the cross- cultural and discipline-specific adaptation of an existing scale addressing this concept in the field of law using the reverse translation method. Second, validation of the scale was carried out from October 2016–June 2017 by studying the psychometric properties of the questionnaire through an analysis of content acceptability and reliability and through exploratory factor analysis (EFA). Results: The questionnaire was designed to be clear, easy to understand, and of adequate length, and experts involved in content validation agreed that the scale meets these criteria. A total of 253 nursing students participated in the validation stage. Four factors were identified from the EFA: (1) patient and health professional behaviours, (2) self-assessments, (3) self-awareness, and (4) cultural influence. Two items were excluded. Factorial saturation is adequate for all factors (>0.30). The Cronbach alpha was measured as 0.75. Conclusions: This study presents the first version of the CUSNUR and demonstrates that the scale is valid and reliable.

وصف الملف: application/pdf

العلاقة: https://hdl.handle.net/10171/63345Test

الإتاحة: https://hdl.handle.net/10171/63345Test

المؤلفون: Samaniego-Vaesken, M.L. (María de Lourdes), Partearroyo, T. (Teresa), Valero, T. (Teresa), Rodriguez, P. (Paula), Soto-Méndez, M.J. (María José), Hernández-Ruiz, Á, (Ángela), Lara-Villoslada, F. (Federico), Leis, R. (Rosaura), Martínez-de-Victoria, E. (Emilio), Moreno, J.M. (José Manuel), Ortega, R.M. (Rosa María), Ruiz-López, M.D. (María Dolores), Gil, A. (Ángel), Varela-Moreiras, G. (Gregorio)

مصطلحات موضوعية: Carbohydrate intakes, pe, EsNuPI study, Pediatrics, Spanish children, Feeding behavior, Dietary habits, Nutrition assessment, Pediatric nutrition, Total sugar

الوصف: Diet quality is a modifiable factor that may contribute to the onset of diet-related chronic diseases. Currently, in Spain there are no studies that examine the intakes and sources for total carbohydrates, starch, total sugar, and fiber by both children consuming all kind of milks and children regularly consuming adapted milk formulas. Our goal was to evaluate the contribution of different food groups to total carbohydrates, starch, total sugar, and fiber consumption within the EsNuPI study participants by assessing their usual intakes by applying two 24 h dietary recalls that were completed by 1448 children (1 to <10 years) divided into two cohorts: one Spanish Reference Cohort (SRS) of the general population (n = 707) and another cohort which included children consuming adapted milks including follow-on milk, toddler’s or growing up milk, fortified and enriched milks, here called Adapted Milk Consumers Cohort” (AMS) (n = 741). Estimation of the usual intake showed that nutrient intake increased with age for all nutrients except for fiber. The percentage of children by age and gender who met the reference intake (RI) range for total carbohydrates, was in all groups more than 50% of individuals, except for girls aged 6 to <10 years from the reference cohort in which only 46.9% complied the RI. Median fiber intake, both in the SRS and the AMS, was well below the adequate intake (AI) for children between 3 and 10 years. Main total carbohydrates sources were cereals, followed by milk and dairy products, fruits, bakery and pastry, vegetables and sugars and sweets. The highest contributors to starch intakes were cereals, bakery and pastry, vegetables, and fruits. Major sources of total sugar intakes were milk and dairy products, fruits, bakery and pastry, sugars and sweets, vegetables, and cereals. Nonetheless, milk and dairy products, and fruits, mainly provided lactose and fructose, respectively, which are not considered free sugars. Higher contribution to fiber intakes was provided by fruits, cereals, ...

وصف الملف: application/pdf

العلاقة: https://hdl.handle.net/10171/65539Test

الإتاحة: https://hdl.handle.net/10171/65539Test

المؤلفون: Cuadrado-Soto, E. (Esther), López-Sobaler, A.M (Ana M.), Jiménez-Ortega, A.I. (Ana Isabel), Aparicio, A. (Aránzazu), Bermejo, L.M. (Laura M.), Hernández-Ruiz, Á, (Ángela), Lara-Villoslada, F. (Federico), Leis, R. (Rosaura), Martínez-de-Victoria, E. (Emilio), Moreno, J.M. (José Manuel), Ruiz-López, M.D. (María Dolores), Soto-Méndez, M.J. (María José), Valero, T. (Teresa), Varela-Moreiras, G. (Gregorio), Gil, A. (Ángel), Ortega, R.M. (Rosa María)

مصطلحات موضوعية: EsNuPI study, Calcium, Phosphoru, Magnesium, Vitamin D, Pediatric nutrition, Food sources, Spanish children, Dairy products, Infant formula

الوصف: Bone problems in the population begin to be establish in childhood. The present study aims to assess the usual calcium, phosphorus, magnesium, and vitamin D intakes, along with the food sources of these nutrients, in Spanish children participating in the EsNuPI (Estudio Nutricional en Población Infantil Española) study. Two 24 h dietary recalls were applied to 1448 children (1 to <10 years) divided into two sub-samples: one reference sample (RS) of the general population [n = 707] and another sample which exclusively included children consuming enriched or fortified milks, here called “adapted milks” (AMS) [n = 741]. Estimation of the usual intake shows that nutrient intake increased with age for all nutrients except vitamin D. Using as reference the Dietary Reference Values from the European Food Safety Authority (EFSA), calcium and magnesium intakes were found to be below the average requirement (AR) and adequate intake (AI), respectively, in a considerable percentage of children. Furthermore, phosphorus exceeded the AI in 100% of individuals and vitamin D was lower than the AI in almost all children studied. The results were very similar when considering only plausible reporters. When analyzing the food sources of the nutrients studied, milk and dairy products contributed the most to calcium, phosphorus, magnesium, and vitamin D. Other sources of calcium were cereals and vegetables; for phosphorus: meat, meat products, and cereals; for magnesium: cereals and fruits; and, for vitamin D: fish and eggs. These results highlight the desirability of improving the intake concerning these nutrients, which are involved in bone and metabolic health in children. The AMS group appeared to contribute better to the adequacy of those nutrients than the RS group, but both still need further improvement. Of special interest are the results of vitamin D intakes, which were significantly higher in the AMS group (although still below the AI), independent of age.

وصف الملف: application/pdf

العلاقة: https://hdl.handle.net/10171/67140Test

الإتاحة: https://hdl.handle.net/10171/67140Test

المؤلفون: Madrigal, C. (Casandra), Soto-Méndez, M.J. (María José), Leis, R. (Rosaura), Hernández-Ruiz, Á, (Ángela), Valero, T. (Teresa), Lara-Villoslada, F. (Federico), Martínez-de-Victoria, E. (Emilio), Moreno, J.M. (José Manuel), Ortega, R.M. (Rosa María), Ruiz-López, M.D. (María Dolores), Varela-Moreiras, G. (Gregorio), Gil, A. (Ángel)

مصطلحات موضوعية: EsNuPI study, Dietary fats, Fats, Lipids, Essential fatty acid, Food sources, Pediatric nutrition, Spanish children, Dairy products, Fortified milk

الوصف: We aimed to determine the usual intake of total fat, fatty acids (FAs), and their main food sources in a representative cohort of the Spanish pediatric population aged 1 to <10 years (n = 707) who consumed all types of milk and an age-matched cohort who consumed adapted milk over the last year (including follow-on formula, toddler’s milk, growing-up milk, and fortified and enriched milks) (n = 741) who were participants in the EsNuPI study (in English, Nutritional Study in the Spanish Pediatric Population). Dietary intake, measured through two 24 h dietary recalls, was compared to the European Food Safety Authority (EFSA) and the Food and Agriculture Organization of the United Nations (UN-FAO) recommendations. Both cohorts showed a high intake of saturated fatty acids (SFAs), according to FAO recommendations, as there are no numerical recommendations for SFAs at EFSA. Also, low intake of essential fatty acids (EFAs; linoleic acid (LA) and α-linolenic acid (ALA)) and long-chain polyunsaturated fatty acids (LC-PUFA) of the n-3 series, mainly docosahexaenoic acid (DHA) were observed according to EFSA and FAO recommendations. The three main sources of total fat and different FAs were milk and dairy products, oils and fats, and meat and meat products. The consumption of adapted milk was one of the main factors associated with better adherence to the nutritional recommendations of total fat, SFAs, EFAs, PUFAs; and resulted as the main factor associated with better adherence to n-3 fatty acids intake recommendations. Knowledge of the dietary intake and food sources of total fat and FAs in children could help in designing and promoting effective and practical age-targeted guidelines to promote the consumption of EFA- and n-3 PUFA-rich foods in this stage of life.

وصف الملف: application/pdf

العلاقة: https://hdl.handle.net/10171/66179Test

الإتاحة: https://hdl.handle.net/10171/66179Test