يعرض 1 - 10 نتائج من 724 نتيجة بحث عن '"Mcknight, J."', وقت الاستعلام: 1.35s تنقيح النتائج
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    المصدر: Ruesch , A , Acharya , D , Bulger , E , Cao , J , Christopher McKnight , J , Manley , M , Fahlman , A , Shinn-Cunningham , B G & Kainerstorfer , J M 2023 , ' Evaluating feasibility of functional near-infrared spectroscopy in dolphins ' , Journal of Biomedical Optics , vol. 28 , no. 7 , 075001 . https://doi.org/10.1117/1.JBO.28.7.075001Test

    الوصف: SIGNIFICANCE Using functional near-infrared spectroscopy (fNIRS) in bottlenose dolphins ( Tursiops truncatus ) could help to understand how echolocating animals perceive their environment and how they focus on specific auditory objects, such as fish, in noisy marine settings. AIM To test the feasibility of near-infrared spectroscopy (NIRS) in medium-sized marine mammals, such as dolphins, we modeled the light propagation with computational tools to determine the wavelengths, optode locations, and separation distances that maximize sensitivity to brain tissue. APPROACH Using frequency-domain NIRS, we measured the absorption and reduced scattering coefficient of dolphin sculp. We assigned muscle, bone, and brain optical properties from the literature and modeled light propagation in a spatially accurate and biologically relevant model of a dolphin head, using finite-element modeling. We assessed tissue sensitivities for a range of wavelengths (600 to 1700 nm), source-detector distances (50 to 120 mm), and animal sizes (juvenile model 25% smaller than adult). RESULTS We found that the wavelengths most suitable for imaging the brain fell into two ranges: 700 to 900 nm and 1100 to 1150 nm. The optimal location for brain sensing positioned the center point between source and detector 30 to 50 mm caudal of the blowhole and at an angle 45 deg to 90 deg lateral off the midsagittal plane. Brain tissue sensitivity comparable to human measurements appears achievable only for smaller animals, such as juvenile bottlenose dolphins or smaller species of cetaceans, such as porpoises, or with source-detector separations ≫100 mm in adult dolphins. CONCLUSIONS Brain measurements in juvenile or subadult dolphins, or smaller dolphin species, may be possible using specialized fNIRS devices that support optode separations of >100 mm. We speculate that many measurement repetitions will be required to overcome hemodynamic signals originating predominantly from the muscle layer above the skull. NIRS measurements of muscle tissue are ...

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    المصدر: Spoors , F , James , M A , Mendo , T , McKnight , J C , Bønnelycke , E-M S & Khan , N 2023 , ' Investigating clove oil and its derivatives as anaesthetic agents for decapod crustaceans to improve welfare commercially and at slaughter ' , Frontiers in Animal Science , vol. 4 , 1180977 . https://doi.org/10.3389/fanim.2023.1180977Test

    الوصف: Decapods have been recently classified as sentient beings in UK policy and therefore the establishment of humane methods for the live transportation and slaughter of commercially valuable shellfish as well as for decapods used in research is critical. Formerly overlooked, the use of anaesthetics provides a promising avenue for improving welfare standards for husbandry and slaughter for decapod crustaceans destined for human consumption or research. In particular, clove oil and its derivatives (eugenol and isoeugenol) have been trialled and recommended in literature as naturally-derived and effective, reversible anaesthetic compounds for a variety of decapods, including two commercially important British shellfish, brown crab ( Cancer pagurus ) and Norway lobster ( Nephrops norvegicus ). Further investigations should be undertaken to confirm the use of such anaesthetics is suitable for improving welfare standards in the British shellfish sector and in research to ensure that when the legislation changes, humane solutions are present.

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    المساهمون: Sea Mammal Research Unit University of St Andrews (SMRU), School of Biology University of St Andrews, University of St Andrews Scotland -University of St Andrews Scotland -Natural Environment Research Council (NERC), Duke University Marine Laboratory, Institut de Génomique Fonctionnelle (IGF), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), The University of Tokyo (UTokyo)

    المصدر: ISSN: 1664-042X ; Frontiers in Physiology ; https://hal.science/hal-04272456Test ; Frontiers in Physiology, 2023, 14, pp.1234432. ⟨10.3389/fphys.2023.1234432⟩.

    الوصف: International audience ; Introduction: The bottlenose dolphin (Tursiops truncatus) is an intermittent breather, where the breath begins with an exhalation followed by inhalation and an extended inter-breath interval ranging from 10 to 40 s. Breathing has been shown to alter both the instantaneous heart rate (if H) and stroke volume (iSV) in the bottlenose dolphin, with a transitory ventilatory tachycardia following the breath, and an exponential decrease to a stable if H around 40 beats • min-1 during the inter-breath period. As the total breath duration in the dolphin is around 1 s, it is not possible to assess the contribution of exhalation and inhalation to these changes in cardiac function during normal breathing. Methods: In the current study, we evaluated the if H response by separating expiration and inspiration of a breath, which allowed us to distinguish their respective contribution to the changes in if H. We studied 3 individual male bottlenose dolphins trained to hold their breath between the different respiratory phases (expiration and inhalation). Results: Our data show that inspiration causes an increase in if H, while expiration appears to result in a decrease in if H. Discussion: These data provide improved understanding of the cardiorespiratory coupling in dolphins, and show how both exhalation and inhalation alters if H.

    العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37811493; hal-04272456; https://hal.science/hal-04272456Test; https://hal.science/hal-04272456/documentTest; https://hal.science/hal-04272456/file/Fahlman%20et%20al-2023.pdfTest; PUBMED: 37811493; PUBMEDCENTRAL: PMC10558176