المؤلفون: Otaegui Irurueta, Imanol, Serra Creus, Bernat, Bellera Gotarda, Neus, Ojeda Ramos, Manuel Tamir, Carmona, Maria Angeles, Lidón Corbi, Rosa María, Bañeras, Jordi, Inserte Igual, Javier, Ferreira González, Ignacio, Martí Aguasca, Gerard, Valente, Filipa, Ruiz Meana, Marisol, miro casas, elisabet, Rodriguez-Sinovas, Antonio, García del Blanco, Bruno, Barrabés, José A., Rodríguez Palomares, Jose Fernando, Sambola Ayala, Antonia, Benito, Begoña, Consegal, Marta, Barba, Ignasi

المساهمون: Institut Català de la Salut, Consegal M, Benito B, Ruiz-Meana M, Inserte J, Rodríguez-Sinovas A Grup de Recerca de Malalties Cardiovasculars, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain. Barba I Grup de Recerca de Malalties Cardiovasculars, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain. Faculty of Medicine, University of Vic - Central University of Catalonia (UVicUCC), Vic, Spain. García Del Blanco B, Otaegui I, Rodríguez-Palomares JF, Martí G, Serra B, Bellera N, Ojeda-Ramos M, Valente F, Carmona MÁ, Miró-Casas E, Sambola A, Lidón RM, Bañeras J, Barrabés JA Grup de Recerca de Malalties Cardiovasculars, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain. Ferreira-González I Grup de Recerca de Malalties Cardiovasculars, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. Centro de Investigación Biomédica en Red (CIBER) de Epidemiología y Salud Pública, CIBERESP, Instituto de Salud Carlos III, Madrid, Spain, Vall d'Hebron Barcelona Hospital Campus

المصدر: Scientia

مصطلحات موضوعية: Infart de miocardi, Reperfusió (Fisiologia), DISEASES::Cardiovascular Diseases::Heart Diseases::Myocardial Ischemia::Myocardial Infarction, CHEMICALS AND DRUGS::Organic Chemicals::Carboxylic Acids::Acids, Acyclic::Dicarboxylic Acids::Succinates::Succinic Acid, ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Surgical Procedures, Operative::Cardiovascular Surgical Procedures::Reperfusion, ENFERMEDADES::enfermedades cardiovasculares::enfermedades cardíacas::isquemia miocárdica::infarto de miocardio, COMPUESTOS QUÍMICOS Y DROGAS::compuestos orgánicos::ácidos carboxílicos::ácidos acíclicos::ácidos dicarboxílicos::succinatos::ácido succínico, TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::intervenciones quirúrgicas::procedimientos quirúrgicos cardiovasculares::reperfusión

الوصف: Cardiovascular biology; Diagnostic markers; Prognostic markers ; Biología cardiovascular; Marcadores de diagnóstico; Marcadores pronósticos ; Biologia cardiovascular; Marcadors diagnòstics; Marcadors pronòstics ; Succinate is enhanced during initial reperfusion in blood from the coronary sinus in ST-segment elevation myocardial infarction (STEMI) patients and in pigs submitted to transient coronary occlusion. Succinate levels might have a prognostic value, as they may correlate with edema volume or myocardial infarct size. However, blood from the coronary sinus is not routinely obtained in the CathLab. As succinate might be also increased in peripheral blood, we aimed to investigate whether peripheral plasma concentrations of succinate and other metabolites obtained during coronary revascularization correlate with edema volume or infarct size in STEMI patients. Plasma samples were obtained from peripheral blood within the first 10 min of revascularization in 102 STEMI patients included in the COMBAT-MI trial (initial TIMI 1) and from 9 additional patients with restituted coronary blood flow (TIMI 2). Metabolite concentrations were analyzed by 1H-NMR. Succinate concentration averaged 0.069 ± 0.0073 mmol/L in patients with TIMI flow ≤ 1 and was significantly increased in those with TIMI 2 at admission (0.141 ± 0.058 mmol/L, p < 0.05). However, regression analysis did not detect any significant correlation between most metabolite concentrations and infarct size, extent of edema or other cardiac magnetic resonance (CMR) variables. In conclusion, spontaneous reperfusion in TIMI 2 patients associates with enhanced succinate levels in peripheral blood, suggesting that succinate release increases overtime following reperfusion. However, early plasma levels of succinate and other metabolites obtained from peripheral blood does not correlate with the degree of irreversible injury or area at risk in STEMI patients, and cannot be considered as predictors of CMR variables. Trial registration: Registered at ...

وصف الملف: application/pdf

العلاقة: Scientific Reports;13; https://doi.org/10.1038/s41598-023-34196-7Test; info:eu-repo/grantAgreement/ES/PE2017-2020/PI17%2F01397; Consegal M, Barba I, García del Blanco B, Otaegui I, Rodríguez-Palomares JF, Martí G, et al. Spontaneous reperfusion enhances succinate concentration in peripheral blood from stemi patients but its levels does not correlate with myocardial infarct size or area at risk. Sci Rep. 2023 Apr 27;13:6907.; https://hdl.handle.net/11351/9482Test

الإتاحة: https://doi.org/10.1038/s41598-023-34196-7Test
https://hdl.handle.net/11351/9482Test

المؤلفون: Tobías-Castillo, Pablo E, Oristrell, Gerard, Reyes-Juárez, José Luis, Martí-Aguasca, Gerard

المساهمون: Montalto, Claudio, Ahmed, Raheel, Akhtar, Waqas, Ali, Kashal, Crawford, Will

المصدر: European Heart Journal - Case Reports ; volume 7, issue 9 ; ISSN 2514-2119

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine

الوصف: Background Ascending aortic pseudoaneurysms (AAPs) are an unusual complication of cardiac or aortic surgery and are associated with a high risk of complications and mortality. Guidelines recommend surgical repair. There is few data concerning percutaneous occlusion of AAP. We present a case of syncope due to vascular and heart chamber compression by a large post-surgical AAP that was filled through a focal leak. Ascending aortic pseudoaneurysm was successfully occluded percutaneously. Case summary A 66-year-old man with a mechanical aortic prosthesis and a Dacron tube in the ascending aorta presented with syncope due to compression of the right atrium and superior vena cava by a large peritube collection. A computed tomography angiography (CTA) showed a large AAP that was filled through a small focal dehiscence of the tube proximal suture. Patient was dismissed for surgery due to high surgical risk. Then, AAP was successfully occluded percutaneously via a 6-French radial access and local anaesthesia. Discussion In patients with syncope and previous cardiac surgery, aortic complications should be ruled out. Although transthoracic echocardiography may be useful, CTA is the recommended diagnostic test for ruling out post-surgical AAP and allows the characterization of the number, localization, and size of the leaks. In selected patients with high surgical risk and favourable anatomic characteristics, a percutaneous closure could be indicated.

الإتاحة: https://doi.org/10.1093/ehjcr/ytad414Test
https://academic.oup.com/ehjcr/article-pdf/7/9/ytad414/51388260/ytad414.pdfTest

المؤلفون: Bianco, Lisa, Marti Aguasca, Gerard, Belahnech, Yassin, Betrián Blasco, Pedro

المصدر: Revista Española de Cardiología (English Edition) ; ISSN 1885-5857

مصطلحات موضوعية: General Medicine

الإتاحة: https://doi.org/10.1016/j.rec.2024.02.013Test
https://api.elsevier.com/content/article/PII:S1885585724000938?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1885585724000938?httpAccept=text/plainTest

المؤلفون: Cruz-Gonzalez, Ignacio, Torres Saura, Francisco, Trejo-Velasco, Blanca, Fernandez Diaz, Jose Antonio, Fajardo Molina, Ricardo, del Valle-Fernandez, Raquel, Martí Aguasca, Gerard

المساهمون: Institut Català de la Salut, Cruz-González I Cardiology Department, University Hospital of Salamanca, Institute of Biomedical Research of Salamanca, Spain. Biomedical Research Networking Center on Cardiovascular Diseases (CIBERCV), Madrid, Spain. Torres Saura F Interventional Cardiology Unit, University Hospital del Vinalopó, Elche, Spain. Trejo-Velasco B Cardiology Department, University Hospital of Salamanca, Institute of Biomedical Research of Salamanca, Spain. Fernández Díaz JA Interventional Cardiology Unit, University Hospital Puerta de Hierro, Madrid, Spain. Fajardo Molina R Cardiology Department, University Hospital Torrecárdenas, Almería, Spain. del Valle-Fernández R Cardiology Department, University Hospital Central de Asturias, Oviedo, Spain. Martí G Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain, Vall d'Hebron Barcelona Hospital Campus

المصدر: Scientia

مصطلحات موضوعية: Fibril·lació auricular, Malalties cerebrovasculars - Prevenció, Avaluació de resultats (Assistència sanitària), DISEASES::Cardiovascular Diseases::Heart Diseases::Arrhythmias, Cardiac::Atrial Fibrillation, ANATOMY::Cardiovascular System::Heart::Heart Atria::Atrial Appendage, DISEASES::Cardiovascular Diseases::Vascular Diseases::Cerebrovascular Disorders::Stroke, Other subheadings::Other subheadings::Other subheadings::/prevention & control, ENFERMEDADES::enfermedades cardiovasculares::enfermedades cardíacas::arritmias cardíacas::fibrilación atrial, ANATOMÍA::sistema cardiovascular::corazón::atrios cardíacos::apéndice atrial, ENFERMEDADES::enfermedades cardiovasculares::enfermedades vasculares::trastornos cerebrovasculares::accidente cerebrovascular, Otros calificadores::Otros calificadores::Otros calificadores::/prevención & control

الوصف: Left atrial appendage; Occlusion; Outcomes ; Apéndice auricular izquierdo; Oclusión; Resultados ; Apèndix auricular esquerre; Oclusió; Resultats ; Background The Watchman FLX is a device upgrade of the Watchman 2.5 that incorporates several design enhancements intended to simplify left atrial appendage occlusion (LAAO) and improve procedural outcomes. This study compares peri-procedural results of LAAO with Watchman FLX (Boston Scientific, Marlborough, Massachusetts) in centers with varying degrees of experience with the Watchman 2.5 and Watchman FLX. Methods Prospective, multicenter, “real-world” registry including consecutive patients undergoing LAAO with the Watchman FLX at 26 Spanish sites (FLX-SPA registry). Implanting centers were classified according to the center’s prior experience with the Watchman 2.5. A further division of centers according to whether or not they had performed ≤ 10 or > 10Watchman FLX implants was prespecified at the beginning of the study. Procedural outcomes of institutions stratified according to their experience with the Watchman 2.5 and FLX devices were compared. Results 359 patients [mean age 75.5 (SD8.1), CHA2DS2-VASc 4.4 (SD1.4), HAS-BLED 3.8(SD0.9)] were included. Global success rate was 98.6%, successful LAAO with the first selected device size was achieved in 95.5% patients and the device was implanted at first attempt in 78.6% cases. There were only 9(2.5%) major peri-procedural complications. No differences in efficacy or safety results according to the centeŕs previous experience with Watchman 2.5 and procedural volume with Watchman FLX existed. Conclusions The Watchman FLX attains high procedural success rates with complete LAA sealing in unselected, real-world patients, along with a low incidence of peri-procedural complications, regardless of operatoŕs experience with its previous device iteration or the number of Watchman FLX devices implanted.

وصف الملف: application/pdf

العلاقة: IJC Heart & Vasculature;38; https://doi.org/10.1016/j.ijcha.2021.100941Test; Cruz-González I, Torres Saura F, Trejo-Velasco B, Antonio Fernández Díaz J, Fajardo Molina R, del Valle-Fernández R, et al. Impact of operatoŕs experience on peri-procedural outcomes with Watchman FLX: Insights from the FLX-SPA registry. IJC Hear Vasc. 2022 Feb;38:100941.; https://hdl.handle.net/11351/8281Test; 000745640300002

الإتاحة: https://doi.org/10.1016/j.ijcha.2021.100941Test
https://hdl.handle.net/11351/8281Test

المؤلفون: Pijuan-Domenech, Antonia, Manso-García, Begoña, Gil-Jaurena, Juan Miguel, Noris Mora, Marta, García-Orta, Rocío, Cano, Óscar, Martí-Aguasca, Gerard, Lacuey, Gemma

المصدر: REC: CardioClinics ; volume 57, page S60-S64 ; ISSN 2605-1532

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine

الإتاحة: https://doi.org/10.1016/j.rccl.2021.10.009Test
https://api.elsevier.com/content/article/PII:S2605153221001266?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2605153221001266?httpAccept=text/plainTest

المؤلفون: Figueras-Coll, Marc, Sabaté-Rotés, Anna, Martí-Aguasca, Gerard, Roguera-Sopena, Marc, Betrián-Blasco, Pedro

المصدر: Anales de Pediatría (English Edition) ; volume 92, issue 2, page 102-104 ; ISSN 2341-2879

مصطلحات موضوعية: Management of Technology and Innovation

الإتاحة: https://doi.org/10.1016/j.anpede.2018.12.012Test
https://api.elsevier.com/content/article/PII:S2341287919302327?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2341287919302327?httpAccept=text/plainTest

المؤلفون: Figueras-Coll, Marc, Sabaté-Rotés, Anna, Martí-Aguasca, Gerard, Roguera-Sopena, Marc, Betrián-Blasco, Pedro

المصدر: Anales de Pediatría ; volume 92, issue 2, page 102-104 ; ISSN 1695-4033

مصطلحات موضوعية: Pediatrics, Perinatology and Child Health

الإتاحة: https://doi.org/10.1016/j.anpedi.2018.12.011Test
https://api.elsevier.com/content/article/PII:S1695403319300098?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1695403319300098?httpAccept=text/plainTest

المؤلفون: Figueras Coll, Marc, Fidalgo García, Andrea, Martí Aguasca, Gerard, Betrian Blasco, P.

المصدر: REC: Interventional Cardiology, ISSN 2604-7306, Vol. 5, Nº. 2, 2023, pags. 129-135

مصطلحات موضوعية: Cardiopatía congénita, Atresia pulmonar, Valvuloplastia con balón, Válvula pulmonar, Recién nacido, Congenital heart defect, Pulmonary atresia, Balloon valvuloplasty, Pulmonary valve, Newborn

الوصف: Introduction and objectives: Pulmonary atresia with intact ventricular septum (PA/IVS) is a rare but serious cyanotic congenital heart disease. Depending on the patient’s anatomy, different therapeutic strategies—surgical or trancatheter—can be planned. The objective of this study was to describe the results of transcatheter pulmonary valve perforation in patients with PA/IVS in a single tertiary center, and compare transjugular to transfemoral approach. The need for additional source of pulmonary flow (ductal stenting or systemic-to-pulmonary artery fistula) at follow-up was reviewed to identify possible risk factors associated with this reintervention. Methods: patients with PA/IVS referred for transcatheter pulmonary valve perforation as first-line therapy from February 2004 through May 2022 were included. Technical procedural details, total procedural and fluoroscopy times, and demographic and echocardiographic data were studied. Results: A total of 22 patients were included. Procedure was successful in 20 cases (91%). The rate of complications was 2/22 (9%). No deaths were reported. The transjugular and transfemoral approaches were equally safe and effective. The total median procedural (n = 20) and fluoroscopy times (n = 16), however, were shorter in the transjugular compared to the transfemoral approach (85 min vs 156 min, and 31 min vs 62 min, respectively), which reached statistical significance. At follow-up, 8/20 (40%) patients needed additional flow (4 ductal stenting, 4 systemic-to-pulmonary artery shunts). No significant risk factors regarding this reintervention were reported. Conclusions: Transcatheter mechanical pulmonary valve perforation may be feasible in expert hands and properly selected patients being an attractive alternative to surgery. In our own experience, transjugular approach seems to simplify the procedure, and reduces procedural and fluoroscopy times. ; Introducción y objetivos: La atresia pulmonar con septo íntegro (APSI) es una cardiopatía congénita cianosante infrecuente que ...

وصف الملف: application/pdf

العلاقة: (Revista) ISSN 2604-7276; (Revista) ISSN 2604-7306; https://dialnet.unirioja.es/servlet/oaiart?codigo=8930446Test

الإتاحة: https://dialnet.unirioja.es/servlet/oaiart?codigo=8930446Test

المؤلفون: de Oliveira-Cañedo, Elena, Andrés-Cordon, Joan F., Martí-Aguasca, Gerard, Vilalta, Victoria, Fernández-Nofrerías, Eduard

المصدر: JACC: Cardiovascular Interventions ; volume 16, issue 13, page 1690-1691 ; ISSN 1936-8798

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine

الإتاحة: https://doi.org/10.1016/j.jcin.2023.03.026Test
https://api.elsevier.com/content/article/PII:S1936879823006222?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1936879823006222?httpAccept=text/plainTest

المؤلفون: Maymí-Ballesteros, Manel, Uribarri, Aitor, Martí-Aguasca, Gerard

المصدر: Revista Española de Cardiología (English Edition) ; volume 76, issue 4, page 282 ; ISSN 1885-5857

مصطلحات موضوعية: General Medicine

الإتاحة: https://doi.org/10.1016/j.rec.2022.09.004Test
https://api.elsevier.com/content/article/PII:S1885585722002390?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1885585722002390?httpAccept=text/plainTest